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anti-Human CD44 Antikörper:
anti-Mouse (Murine) CD44 Antikörper:
anti-Rat (Rattus) CD44 Antikörper:
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Mouse (Murine) Monoclonal CD44 Primary Antibody für BR, IHC (fro) - ABIN1176866
Hathcock, Hirano, Murakami, Hodes: CD44 expression on activated B cells. Differential capacity for CD44-dependent binding to hyaluronic acid. in Journal of immunology (Baltimore, Md. : 1950) 1994
Show all 23 Pubmed References
Mouse (Murine) Monoclonal CD44 Primary Antibody für BR, CyTox - ABIN2689261
Bendelac: Mouse NK1+ T cells. in Current opinion in immunology 1995
Show all 23 Pubmed References
Mouse (Murine) Monoclonal CD44 Primary Antibody für FACS - ABIN2689265
Brocke, Piercy, Steinman, Weissman, Veromaa: Antibodies to CD44 and integrin alpha4, but not L-selectin, prevent central nervous system inflammation and experimental encephalomyelitis by blocking secondary leukocyte recruitment. in Proceedings of the National Academy of Sciences of the United States of America 1999
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Human Polyclonal CD44 Primary Antibody für IHC (p), WB - ABIN3043394
Cui, Qi, Guo, Qin, Gui, Cai: Rat bone marrow derived mesenchymal progenitor cells support mouse ES cell growth and germ-like cell differentiation. in Cell biology international 2009
Show all 17 Pubmed References
Mouse (Murine) Monoclonal CD44 Primary Antibody für BR, IHC (f) - ABIN1176842
Castro, Bono, Simon, Vargas, Rosemblatt: Spleen-derived stromal cells. Adhesion molecules expression and lymphocyte adhesion to reticular cells. in European journal of cell biology 1998
Show all 15 Pubmed References
Mouse (Murine) Monoclonal CD44 Primary Antibody für BR, IHC (f) - ABIN967622
Godfrey, Kennedy, Suda, Zlotnik: A developmental pathway involving four phenotypically and functionally distinct subsets of CD3-CD4-CD8- triple-negative adult mouse thymocytes defined by CD44 and CD25 expression. in Journal of immunology (Baltimore, Md. : 1950) 1993
Show all 16 Pubmed References
Mouse (Murine) Monoclonal CD44 Primary Antibody für IHC (f), IHC (fro) - ABIN2689263
Hyman, Lesley, Schulte, Trotter: Progenitor cells in the thymus: most thymus-homing progenitor cells in the adult mouse thymus bear Pgp-1 glycoprotein but not interleukin-2 receptor on their cell surface. in Cellular immunology 1986
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Human Monoclonal CD44 Primary Antibody für CyTOF, FACS - ABIN4900587
Draffin, McFarlane, Hill, Johnston, Waugh: CD44 potentiates the adherence of metastatic prostate and breast cancer cells to bone marrow endothelial cells. in Cancer research 2004
Show all 11 Pubmed References
Human Monoclonal CD44 Primary Antibody für CyTOF, FACS - ABIN4900724
Dingemans, Ramkema, Pals: CD44 is exposed to the extracellular matrix at invasive sites in basal cell carcinomas. in Laboratory investigation; a journal of technical methods and pathology 2002
Show all 10 Pubmed References
Human Monoclonal CD44 Primary Antibody für FACS, ICC - ABIN457344
Si-Tahar, Sitaraman, Shibahara, Madara: Negative regulation of epithelium-neutrophil interactions via activation of CD44. in American journal of physiology. Cell physiology 2001
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pERK1/2 is a regulator of CD44 expression, and increased CD44 expression leads to a pro-sclerotic and migratory parietal epithelial cell phenotype in focal segmental glomerulosclerosis.
MET signaling regulates intestinal homeostasis and regeneration, as well as adenoma formation. These activities of MET are promoted by the stem cell CD44 isoform CD44v4-10.
study demonstrates that CD44 plays a critical role in the regulation of experimental autoimmune encephalomyelitis through alterations in the gut microbiome profile and short-chain fatty acid production
CD44 variant isoform 9 emerges in response to injury and contributes to the regeneration of the gastric epithelium.
OA/GPNMB acts through ERK (zeige EPHB2 Antikörper) and AKT (zeige AKT1 Antikörper) signaling pathways in mesenchymal stem cells via CD44
These findings support the usefulness of the conditional Cd44 allele in unraveling essential physiological and pathological functions of CD44 isoforms.
CD44 role in the atrophic epidermis
CD44(high) type II cells likely represent a type II cell subpopulation important for constitutive regulation of alveolar homeostasis.
CD44V6 is part of a positive-feedback loop with TGFbeta1 (zeige TGFB1 Antikörper)/TGFbetaRI signaling that acts to increase NOX4 (zeige NOX4 Antikörper)/ROS (zeige ROS1 Antikörper) production, which is required for myofibroblast differentiation, myofibroblast differentiation, myofibroblast extracellular matrix production, myofibroblast invasion, and myofibroblast contractility.
HAS2 (zeige HAS2 Antikörper)-produced hyaluronan is required for CD44V6 and TGFbetaRI co-localization and subsequent CD44V6/ERK1 (zeige MAPK3 Antikörper)/EGR1 (zeige EGR1 Antikörper) signaling. These results demonstrate a novel positive-feedback loop that links the myofibroblast phenotype to TGFbeta1 (zeige TGFB1 Antikörper)-stimulated CD44V6/ERK (zeige EPHB2 Antikörper)/EGR1 (zeige EGR1 Antikörper) signaling.
Increased CD44s protein and posttranslational modification of CD44 with polylactosamine on macrophages from stage III could be involved in the cleaning up apoptotic granulosa cells
CD44 has a key role in oocyte maturation but not in cumulus expansion.
This study demonstrates that the CD14 (zeige CD14 Antikörper)-negative isolation yields an enhanced cell population SFB (zeige CEBPB Antikörper) that is more potent than MSCP (zeige SLC25A37 Antikörper) as a cell source for cartilage tissue engineering.
CD44 is expressed in the cumulus-oocyte complexes during cumulus expansion. The interaction between hyaluronan and CD44 is closely related to gap junctional communication of the cumulus-oocyte complexes during meiotic resumption.
The rates of CD44st and MMP2 (zeige MMP2 Antikörper) expression were higher in squamous cell carcinomas than in adenocarcinomas, were closely associated with lymph node metastasis and TNM (zeige ODZ1 Antikörper) stage, and affected patients' prognoses.
suggest that upregulation of NG2/CSPG4 (zeige MCSP Antikörper) rather than changes in CD44 or Ki-67 (zeige MKI67 Antikörper) expression is associated with low overall survival in glioblastoma multiforme patients, supporting NG2/CSPG4 (zeige MCSP Antikörper) as a potential prognostic marker in glioblastoma
Suggest that CD44-positivity might be a candidate tumor stem cell marker in intrahepatic cholangiocarcinoma and a prognostic indicator.
Mechanistically, CD44v interacts with and stabilizes xCT (zeige SLC7A11 Antikörper) and thereby promotes the uptake of cysteine for glutathione synthesis and stimulates side-population cell enrichment.
These tumor samples express CD44 protein at low rather than high levels. There is no correlation between CLDN3 (zeige CLDN3 Antikörper) gene expression and protein expression in these CPTAC samples; hence, the claudin-low subtype defined by gene expression is not the same group of tumors as that defined by low expression of CLDN3 (zeige CLDN3 Antikörper) protein.
this study shows that genkwadaphnin promotes leukocyte migration by increasing CD44 expression via PKD1 (zeige PKD1 Antikörper)/NF-kappaB (zeige NFKB1 Antikörper) signaling pathway
High CD44 expression is associated with high grade glioma.
CNS disease was associated with enhanced expression of cytoplasmic and membranous ITGA10 and nuclear PTEN (zeige PTEN Antikörper) (P < 0.0005, P = 0.002, P = 0.024, respectively). sCNSL presented decreased membranous CD44 and nuclear and cytoplasmic cadherin-11 expressions (P = 0.001, P = 0.006, P = 0.048, respectively). In PCNSL lactoferrin (zeige LTF Antikörper) expression was upregulated (P < 0.0005).
In clinical specimens of breast cancer, authors established that the expression of CD44s and HAS2 (zeige HAS2 Antikörper) was positively correlated. Results establish a positive feedback mechanism that sustains PI3K (zeige PIK3CA Antikörper)/Akt (zeige AKT1 Antikörper) signaling in tumor cells, further illuminating the nearly universal role of this pathway in cancer cell survival.
In regulation of tumour cells with high CD44 expression.
CD44 knock-down in bovine and human chondrocytes results in release of bound HYAL2 (zeige HYAL2 Antikörper).
release of the CD44 intracellular domain into the cytoplasm of cells such as chondrocytes exerts a competitive or dominant-negative effect on the function of full-length CD44.
CD44 fragmentation, consistent with a signature pattern reported for sequential metalloproteinase/gamma-secretase cleavage of CD44, is a common metabolic feature of chondrocytes that have undergone dedifferentiation in vitro
determined the effects of Mycobacterium-induced proliferation and apoptosis on CD25 (zeige IL2RA Antikörper), CD44, and CD62L (zeige SELL Antikörper) expression on peripheral blood T-cell subsets from M. bovis-infected cattle.
detection of CD44 in the bovine oviductal epithelium
Oligosaccharides of hyaluronan induce angiogenesis through distinct CD44 and RHAMM (zeige HMMR Antikörper)-mediated signalling pathways involving Cdc2 (zeige CDK1 Antikörper) and gamma-adducin (zeige ADD3 Antikörper).
The novel finding that TSP-1 (zeige THBS1 Antikörper)-induced migration is dependent on the CD44 receptor links 2 pathways thought to be disparate (ie, TSP-1 (zeige THBS1 Antikörper) and HyA (zeige KDM5D Antikörper)).
An important role for the Hyaluronan-CD44 signaling pathway in reproductive function and inflammation.
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.
, GP90 lymphocyte homing/adhesion receptor
, Hermes antigen
, cell surface glycoprotein CD44
, chondroitin sulfate proteoglycan 8
, extracellular matrix receptor III
, hematopoietic cell E- and L-selectin ligand
, heparan sulfate proteoglycan
, homing function and Indian blood group system
, hyaluronate receptor
, phagocytic glycoprotein 1
, hermes antigen
, lymphocyte antigen 24
, phagocytic glycoprotein I
, Cell surface glycoprotein CD44 (hyaluronate binding protein)
, CD44-like protein
, extracellular matrix receptor-III
, lymphocyte surface antigen precursor CD44
, CD44 molecule (Indian blood group) S homeolog
, hyaluronan receptor CD44