anti-Beclin 1 (BECN1) Antikörper

Auf finden Sie aktuell 438 Beclin 1, Autophagy Related (BECN1) Antikörper von 28 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Beclin 1 Kits (45) und Beclin 1 Proteine (19) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 524 Beclin 1 Produkte verfügbar.
4921513J16Rik, 5430417M23Rik, Atg6, Beclin-1, beclin1, becn1, VPS30, zgc:73097
Alle Antikörper anzeigen Gen GeneID UniProt
BECN1 8678 Q14457
BECN1 56208 O88597
BECN1 114558 Q91XJ1

Meistgesuchte Reaktivitäten zu anti-Beclin 1 (BECN1) Antikörper

anti-Human Beclin 1 Antikörper:

anti-Mouse (Murine) Beclin 1 Antikörper:

anti-Rat (Rattus) Beclin 1 Antikörper:

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Weitere Antikörper gegen Beclin 1 Interaktionspartner

Zebrafish Beclin 1, Autophagy Related (BECN1) Interaktionspartner

  1. Beclin1 plays an important role in vincristine-induced dopaminergic neurons toxicity.

Human Beclin 1, Autophagy Related (BECN1) Interaktionspartner

  1. Data suggest that BECN1 exhibits a helical region that transitions between packing (folding/unfolding) as part of either one of two conserved domains; packing of this helical region appears to have important implications for relative stability of autophagy-inactive and autophagy-active BECN1 complexes.

  2. downregulation of HOXC9 (zeige HOXC9 Antikörper) releases its transcriptional inhibition of DAPK1 (zeige DAPK1 Antikörper), resulting in the activation of the DAPK1 (zeige DAPK1 Antikörper)-Beclin1 pathway, which induces autophagy in glioblastoma cells

  3. ASPP2 (zeige TP53BP2 Antikörper) is a key regulator of BECN1-dependent autophagy.

  4. the polyQ domain enables wild-type ataxin 3 (zeige ATXN3 Antikörper) to interact with beclin 1, a key initiator of autophagy; this interaction allows the deubiquitinase activity of ataxin 3 (zeige ATXN3 Antikörper) to protect beclin 1 from proteasome-mediated degradation and thereby enables autophagy

  5. findings suggest that expression of cFLIPL regulates the basal interaction of Bcl-2 (zeige BCL2 Antikörper) with Beclin-1 and substantiates p53 (zeige TP53 Antikörper) dependent ubiquitination of Beclin-1 during autophagic stress to determine the fate of cell death or survival.

  6. Here, sequence analyses, structural modeling, mutagenesis combined with pull-down assays, X-ray crystal structure determination and small-angle X-ray scattering were used to investigate the Beclin 1-GAPR-1 interaction. changes in the structure of the equatorial groove combined with the improved dimerization of pentad mutant GAPR-1 are likely to abrogate binding to Beclin 1.

  7. Acetylated PGK1 (zeige PGK1 Antikörper) binds to and phosphorylates Beclin1 at S30 (zeige FAU Antikörper), leading to activation of the VPS34 (zeige PIK3C3 Antikörper)-Beclin1 complex to initiate autophagosomal formation.

  8. reactive oxygen species (ROS (zeige ROS1 Antikörper)) production was induced, which increased RelA (zeige NFkBP65 Antikörper) transcriptional activity and beclin 1 (BECN1) expression in oral cancer cells irradiated with LPL (zeige LCP1 Antikörper)

  9. Further data showed that reactive oxygen species-c-Jun (zeige JUN Antikörper) activation by HBx resulted in the release of beclin-1 from its association with beclin-2 to form a complex with VPS34 (zeige PIK3C3 Antikörper), thus enhancing autophagosome formation.

  10. Beclin1 interacts with both the N- and C-termini of LAPTM4B. Beclin1 competes with EGFR for LAPTM4B binding.

Mouse (Murine) Beclin 1, Autophagy Related (BECN1) Interaktionspartner

  1. Genetically disrupting BECN1-BCL2 (zeige BCL2 Antikörper) binding hyperactivates autophagy in vivo, which sequestrates amyloid oligomers and prevents Alzheimer's disease progression.

  2. Data show that 1-month of oral treatment with beta-asarone reduces AChE, Abeta42, APP (zeige APP Antikörper) and Beclin-1 levels and alleviates some behavioral impairments by inhibiting the autophagy via regulating the PI3K/Akt (zeige AKT1 Antikörper)/mTOR (zeige FRAP1 Antikörper) pathway in APP (zeige APP Antikörper)/PS1 (zeige PSEN1 Antikörper) transgenic mice. The results further support the exploration of beta-asarone as a possible disease-modifying agent for the treatment of Alzheimer's disease.

  3. identify FAK (zeige PTK2 Antikörper) as a novel negative regulator of Beclin1-mediated autophagy and indicate that this pathway can facilitate the promotion of compensatory hypertrophic growth

  4. The results not only demonstrate that BECN1 as a PI3K-III component is essential for cytokinesis, but also suggest that BECN1 is not associated with autophagy pathway in mouse oocytes.

  5. this study shows that knockdown of beclin1 enhances macrophage-associated (zeige CD163 Antikörper) phagocytosis and intracellular killing of Pseudomonas aeruginosa

  6. provide the novel evidence that GADD45A (zeige GADD45A Antikörper) inhibits autophagy via impairing the BECN1-PIK3C3 (zeige PIK3C3 Antikörper) complex formation

  7. in-vitro genetic depletion of beclin-1 in high glucose treated adult rat cardiomyocytes markedly inhibited the level of autophagy and subsequent apoptotic cell death.

  8. suggest that neuronal death induced by decreased beclin 1 levels may also be due to impaired trophic factor signaling

  9. FBG1 (zeige FBXO2 Antikörper) degrades A1AT (zeige SERPINA1 Antikörper)-Z through a Beclin1-dependent arm of autophagy.

  10. Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG (zeige UVRAG Antikörper)-VPS34 (zeige PIK3C3 Antikörper) complex.

Pig (Porcine) Beclin 1, Autophagy Related (BECN1) Interaktionspartner

  1. Data indicate that the expression of MAP1LC3A (zeige MAP1LC3A Antikörper), B and autophagy-associated genes (ATG5 (zeige ATG5 Antikörper), mTOR (zeige FRAP1 Antikörper), Beclin-1) was increased in normal pigs, while decreased in miniature pigs.

Beclin 1 (BECN1) Antigen-Profil

Beschreibung des Gens

Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration (Zhong et al., 2009

Alternative names and synonyms associated with Beclin 1 (BECN1)

  • beclin 1, autophagy related (BECN1) Antikörper
  • beclin 1, autophagy related (becn1) Antikörper
  • beclin 1 (atg6) Antikörper
  • beclin 1 protein (atg6) Antikörper
  • beclin-1 (CpipJ_CPIJ011087) Antikörper
  • beclin-1 (PTRG_07825) Antikörper
  • beclin-1 (SJAG_01876) Antikörper
  • Beclin-1 (becn1) Antikörper
  • beclin 1 (coiled-coil, myosin-like BCL2 interacting protein) (becn1) Antikörper
  • beclin 1, autophagy related (Becn1) Antikörper
  • beclin-1-like (LOC100352353) Antikörper
  • 4921513J16Rik Antikörper
  • 5430417M23Rik Antikörper
  • Atg6 Antikörper
  • Beclin-1 Antikörper
  • beclin1 Antikörper
  • becn1 Antikörper
  • VPS30 Antikörper
  • zgc:73097 Antikörper

Bezeichner auf Proteinebene für BECN1

beclin 1 (coiled-coil, myosin-like BCL2 interacting protein) , beclin-1 , beclin 1 , GRMZM2G092112 , beclin 1 proteinBeclin-1-like protein , Beclin-1 , myosin-like BCL2 interacting protein , ATG6 autophagy related 6 homolog , beclin 1 (coiled-coil, moesin-like BCL2 interacting protein) , beclin 1 (coiled-coil, moesin-like BCL2-interacting protein) , coiled-coil myosin-like BCL2-interacting protein , Bcl-2-interacting protein beclin , coiled-coil, myosin-like BCL2-interacting protein , beclin 1 (coiled-coil, myosin-like BCL2-interacting protein) , autophagy-related protein 6

454700 Pan troglodytes
619357 Xenopus (Silurana) tropicalis
653027 Takifugu rubripes
711649 Macaca mulatta
732797 Zea mays
6043853 Culex quinquefasciatus
6346099 Pyrenophora tritici-repentis Pt-1C-BFP
7048057 Schizosaccharomyces japonicus yFS275
100049387 Oryzias latipes
100136134 Oncorhynchus mykiss
100173145 Pongo abelii
100194789 Salmo salar
393846 Danio rerio
8678 Homo sapiens
56208 Mus musculus
444178 Xenopus laevis
420018 Gallus gallus
733576 Sus scrofa
527278 Bos taurus
114558 Rattus norvegicus
480513 Canis lupus familiaris
100721231 Cavia porcellus
100913170 Ovis aries
100352353 Oryctolagus cuniculus
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