GZMA Proteine (GZMA)

Bezeichnung:
Granzyme A (Granzyme 1, Cytotoxic T-Lymphocyte-Associated serine Esterase 3) Proteine (GZMA)
Auf www.antikoerper-online.de finden Sie aktuell 17 Granzyme A (Granzyme 1, Cytotoxic T-Lymphocyte-Associated serine Esterase 3) (GZMA) Proteine von 10 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen GZMA Antikörper (123) und GZMA Kits (30) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 178 GZMA Produkte verfügbar.
Synonyme:
AW494114, Ctla-3, CTLA3, GZMA, Hf, HFSP, SE1, TSP-1, TSP1
alle Proteine anzeigen Gen GeneID UniProt
GZMA 14938 P11032
Ratte GZMA GZMA 266708  
GZMA 3001 P12544

Weitere Synonyme anzeigen

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Am meisten referenzierte GZMA Proteine

  1. Human GZMA Protein expressed in HEK-293 - ABIN2666491 : Edwards, Kam, Powers, Trapani: The human cytotoxic T cell granule serine protease granzyme H has chymotrypsin-like (chymase) activity and is taken up into cytoplasmic vesicles reminiscent of granzyme B-containing endosomes. in The Journal of biological chemistry 1999 (PubMed)
    Zeige alle 6 Referenzen für 2666491

Weitere Proteine zu GZMA Interaktionspartnern

Mouse (Murine) Granzyme A (Granzyme 1, Cytotoxic T-Lymphocyte-Associated serine Esterase 3) (GZMA) Interaktionspartner

  1. this study shows that gzmA and gzmB partly regulate local inflammation during early pneumonia but eventually play an insignificant role during pneumosepsis by the common human pathogen Klebsiella pneumoniae

  2. Granzyme A does not have a crucial role in vivo in the protective response to tuberculosis.

  3. The results, in susceptible B6 mice for GzmB and in resistant 129/Sv mice for GzmA and/or the GzmB cluster, point to granzyme-mediated host defense regulation in the liver in experimental visceral leishmaniasis.

  4. Estrogen increases the extracellular expression and interleukin (IL)-12 (zeige IL12A Proteine)-induced activity of a critical member of serine protease (zeige F2 Proteine) family granzyme A.

  5. functional divergence between human and mouse granzyme A

  6. Regulated secretion of granzyme A and cytotoxic killing was enhanced and correlated with increased vesicle-associated membrane protein 7 (zeige VAMP7 Proteine) availability.

  7. GzmA deficiency in filarial infection is linked with reduced inflammation and a trend toward increased alternatively activated macrophages.

  8. granzyme A- and B-cluster deficiency delays the acute progression of pneumovirus disease by reducing alveolar injury.

  9. the genes for perforin (zeige PRF1 Proteine), the three major T cell granzymes (A-C) and IFN-gamma (zeige IFNG Proteine) are differentially expressed during primary activation of naive CD8 (zeige CD8A Proteine)(+) T cells, kinetically and at the single-cell level

  10. granzyme A and granzyme B have a similar potential to induce rapid perf-mediated apoptosis but that their individual contribution to the underlying intracellular process is dictated by the quality of the target cell

Human Granzyme A (Granzyme 1, Cytotoxic T-Lymphocyte-Associated serine Esterase 3) (GZMA) Interaktionspartner

  1. GzmA plays an unfavorable role in host defense during pneumococcal pneumonia by a mechanism that does not depend on natural killer cells.

  2. Carbamate pesticides significantly reduced the intracellular levels of perforin (zeige PRF1 Proteine), GrA (zeige NR3C1 Proteine), GrB, Gr3 (zeige PRLHR Proteine)/K, and GRN (zeige GRN Proteine) in NK-92CI cells.

  3. Our results suggest that granzyme A could be considered another biomarker of TB, that can be used, other than IFN-gamma (zeige IFNG Proteine), to discriminate between patients with active TB and LTBI subjects

  4. Delivered into parasite infected cells by granulysin (zeige GNLY Proteine) and perforin (zeige PRF1 Proteine), granzymes generate superoxide and inactivate oxidative defense enzymes to kill the parasite.

  5. Taken together, the authors verified that histone H3 (zeige HIST3H3 Proteine) is a real substrate for GzmA in vivo in the Raji cells treated by staurosporin.

  6. Results reveal enhanced intra- and extracellular expression of gzmA and B in patients with pulmonary TB, suggesting that gzms are part of the host response to tuberculosis.

  7. Levels of GZMA and ITGAE (zeige ITGAE Proteine) mRNAs in colon tissues can identify patients with UC who are most likely to benefit from etrolizumab; expression levels decrease with etrolizumab administration in biomarker(high) patients.

  8. GzmA and GzmB expressing cells in the airways and lung parenchyma was higher in subjects who died from asthma

  9. GZMA, GBP5 and CD64 (zeige FCGR1A Proteine) genes show promise as a rapid diagnostic markers separating tuberculosis from other pulmonary diseases.

  10. We herewith identify GZMA as critical effector molecule of human Treg function for gastrointestinal immune response in an experimental GvHD model.

GZMA Protein Überblick

Protein Überblick

Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells.

Alternative names and synonyms associated with GZMA

  • granzyme A (gzmA)
  • granzyme A (GZMA)
  • Granzyme A (graa)
  • granzyme A (Gzma)
  • granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) (GZMA)
  • AW494114 Protein
  • Ctla-3 Protein
  • CTLA3 Protein
  • GZMA Protein
  • Hf Protein
  • HFSP Protein
  • SE1 Protein
  • TSP-1 Protein
  • TSP1 Protein

Bezeichner auf Proteinebene für GZMA

granzyme A , Granzyme A , BLT esterase , H factor , Hanukah factor , autocrine thymic lymphoma granzyme-like serine protease , fragmentin-1 , serine esterase 1 , t cell-specific serine protease 1 , CTL tryptase , Granzyme A (Cytotoxic T-lymphocyte-associated serine esterase-3; Hanukah factor serine protease) , HF , cytotoxic T-lymphocyte proteinase 1 , h factor

GENE ID SPEZIES
407178 Bos taurus
100113480 Felis catus
100196008 Salmo salar
14938 Mus musculus
266708 Rattus norvegicus
3001 Homo sapiens
100526762 Sus scrofa
539093 Bos taurus
487207 Canis lupus familiaris
395108 Gallus gallus
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