anti-Caspase 4 (CASP4) Antikörper

anti-Caspase 4, Apoptosis-Related Cysteine Peptidase Antikörper (CASP4)
Auf finden Sie aktuell 263 Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) Antikörper von 29 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Caspase 4 Kits (54) und Caspase 4 Proteine (25) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 358 Caspase 4 Produkte verfügbar.
CASP1, CASP4, Casp11, CASP13, Caspl, ICE(rel)II, ICEREL-II, ICH-2, ich-3, Mih1/TX, TX
Alle Antikörper anzeigen Gen GeneID UniProt
CASP4 837 P49662
CASP4 12363 P70343
CASP4 114555  

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Meistgesuchte Reaktivitäten zu anti-Caspase 4 (CASP4) Antikörper

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anti-Human Caspase 4 Antikörper:

anti-Mouse (Murine) Caspase 4 Antikörper:

anti-Rat (Rattus) Caspase 4 Antikörper:

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Am meisten referenzierte anti-Caspase 4 Antikörper

  1. Human Monoclonal Caspase 4 Primary Antibody für ELISA, ICC - ABIN265762 : Kenneth, Younger, Hughes, Marcotte, Barker, Saunders, Duckett: An inactivating caspase 11 passenger mutation originating from the 129 murine strain in mice targeted for c-IAP1. in The Biochemical journal 2012 (PubMed)
    Zeige alle 21 Referenzen für 265762

  2. Human Polyclonal Caspase 4 Primary Antibody für IHC (p), WB - ABIN121890 : Cohen: Caspases: the executioners of apoptosis. in The Biochemical journal 1997 (PubMed)
    Zeige alle 4 Referenzen für 121890

  3. Human Polyclonal Caspase 4 Primary Antibody für IHC (p), WB - ABIN3043186 : Ji, Yan, Li, Lai, Liu: Therapeutic effects of intrathecal versus intravenous monosialoganglioside against bupivacaine-induced spinal neurotoxicity in rats. in Biomedicine & pharmacotherapy = Biome?decine & pharmacothe?rapie 2015 (PubMed)
    Zeige alle 2 Referenzen für 3043186

  4. Human Monoclonal Caspase 4 Primary Antibody für WB - ABIN967534 : Faucheu, Diu, Chan, Blanchet, Miossec, Hervé, Collard-Dutilleul, Gu, Aldape, Lippke: A novel human protease similar to the interleukin-1 beta converting enzyme induces apoptosis in transfected cells. in The EMBO journal 1995 (PubMed)
    Zeige alle 2 Referenzen für 967534

  5. Human Polyclonal Caspase 4 Primary Antibody für ELISA, WB - ABIN185284 : Munday, Vaillancourt, Ali, Casano, Miller, Molineaux, Yamin, Yu, Nicholson: Molecular cloning and pro-apoptotic activity of ICErelII and ICErelIII, members of the ICE/CED-3 family of cysteine proteases. in The Journal of biological chemistry 1995 (PubMed)

  6. Mouse (Murine) Polyclonal Caspase 4 Primary Antibody für WB - ABIN222879 : Huang, Xie, Qiao, Qiu, Huang, Li, Chen, Liu, Wang, Lin, Wang: Caspase-11 plays an essential role in methamphetamine-induced dopaminergic neuron apoptosis. in Toxicological sciences : an official journal of the Society of Toxicology 2015 (PubMed)

  7. Human Polyclonal Caspase 4 Primary Antibody für WB - ABIN222883 : Kim, Zhang, Hitomi, Lee, Mukherjee: Endoplasmic reticulum stress-induced caspase-4 activation mediates apoptosis and neurodegeneration in INCL. in Human molecular genetics 2006 (PubMed)

Weitere Antikörper gegen Caspase 4 Interaktionspartner

Human Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) Interaktionspartner

  1. Pathophysiological studies showed that the overexpression of the CASP4 gene was involved in the loss of proximal tubules and renal injury in nephropathic cystinosis patients. Considering kidney's key roles in sodium filtration and reabsorption CASP4 genes are involved in Blood Pressure regulation.

  2. We propose that microglial caspase-4 expression contributes to the cognitive impairments in Alzheimer's disease (AD), and that further study of caspase-4 will enhance our understanding of AD pathogenesis and may lead to novel therapeutic targets in AD.

  3. this study shows that activation of caspase-4 is mediated by interactions with endotoxin-rich membrane interfaces rather than by endotoxin monomers

  4. Specific activation of caspase-3 (zeige CASP3 Antikörper) and caspase-4 was found in proplatelets. Consistent with previous observations of caspase-4 autoactivation in response to endoplasmic reticulum (ER) stress, several ER stress marker proteins were expressed during proplatelet formation.

  5. apoptosis is induced by rhein traditional Chinese medicine via induction of endoplasmic reticulum stress, caspase-4 and intracellular calcium in primary human hepatic HL-7702 cells

  6. Caspase-4 and caspase-5 (zeige CASP5 Antikörper) mediate IL-1alpha and IL-1beta (zeige IL1B Antikörper) release from human monocytes after lipopolysaccharides stimulation.

  7. both caspase-4 and caspase-5 (zeige CASP5 Antikörper) are functionally important for appropriate responses to intracellular Gram-negative bacteria.

  8. caspase-4 activation alone is sufficient to induce pyroptosis, this process depends on the NLRP3 (zeige NLRP3 Antikörper) inflammasome activation to drive IL-1beta (zeige IL1B Antikörper) maturation.

  9. This study reveled that CASP4 having a central role in the bipolar disease and schizophrenia manifestation.

  10. NF-kappaB (zeige NFKB1 Antikörper) can mediate Fas (zeige FAS Antikörper)-induced apoptosis through caspase-4 protease

Mouse (Murine) Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) Interaktionspartner

  1. Caspase-11 targets cofilin (zeige CFL1 Antikörper) via the RhoA GTPase, whereas caspase-1 (zeige CASP1 Antikörper) engages the Slingshot phosphatase

  2. Hyperactive dendritic cells induce potent adaptive immune responses and are elicited by caspase-11, an enzyme that binds oxidized phospholipids and bacterial lipopolysaccharide.

  3. Caspase-1 (zeige CASP1 Antikörper)-activated IL-18 (zeige IL18 Antikörper) induces IFN-gamma (zeige IFNG Antikörper) to prime caspase-11 and rapidly clear Burkholderia thailandensis infection.

  4. These results argue that caspase-1 (zeige CASP1 Antikörper), -4 or -5 can be recruited to inflammasomes under specific circumstances, often leading to distinctly organized and localized complexes that may impact the functions of these proteases

  5. gasdermin D is essential for caspase-11-dependent pyroptosis and interleukin-1beta maturation

  6. But not in Casp11(-/-), Panx1 (zeige PANX1 Antikörper)(-/-), or P2x7 (zeige P2RX7 Antikörper)(-/-) mice.

  7. active caspase-11 leads to a drop of intracellular potassium levels, which is necessary to activate NLRP3 (zeige NLRP3 Antikörper).

  8. Data show that caspase-1 (zeige CASP1 Antikörper) but not caspase-11 was essential for the functional activities of the NLRC4 (zeige NLRC4 Antikörper) inflammasome.

  9. Data indicate that genetic ablation of caspase-1 (zeige CASP1 Antikörper) and -11 from cpdm (zeige SHARPIN Antikörper) mice significantly reduced skin inflammation in sharpin (zeige SHARPIN Antikörper)-deficient mice.

  10. These results suggest a role for other caspase-11 effector mechanisms such as pyroptosis in protection against intestinal inflammation.

Caspase 4 (CASP4) Antigen-Profil

Beschreibung des Gens

This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.

Alternative names and synonyms associated with Caspase 4 (CASP4)

  • caspase 4 (CASP4) Antikörper
  • caspase 11 (LOC100101589) Antikörper
  • caspase 4, apoptosis-related cysteine peptidase (CASP4) Antikörper
  • caspase 4, apoptosis-related cysteine peptidase (Casp4) Antikörper
  • caspase-4-like (LOC100359184) Antikörper
  • CASP1 Antikörper
  • CASP4 Antikörper
  • Casp11 Antikörper
  • CASP13 Antikörper
  • Caspl Antikörper
  • ICE(rel)II Antikörper
  • ICEREL-II Antikörper
  • ICH-2 Antikörper
  • ich-3 Antikörper
  • Mih1/TX Antikörper
  • TX Antikörper

Bezeichner auf Proteinebene für CASP4

caspase 4 , CASP-4 , ICE(rel)-II , apoptotic cysteine protease Mih1/TX , caspase 4, apoptosis-related cysteine protease , caspase-4 , protease ICH-2 , protease TX , CASP-11 , caspase 11, apoptosis-related cysteine peptidase , caspase 11, apoptosis-related cysteine protease , caspase-11 short form splicing , protease ICH-3 , caspase 11 , CASP-1 , ICE , IL-1 beta-converting enzyme , IL-1BC , caspase-1 , caspase-1/caspase-4 hybrid , interleukin-1 beta convertase , interleukin-1 beta-converting enzyme , p45 , CASP-13 , ERICE , caspase 13 , caspase-13 , evolutionary related interleukin-1-beta-converting enzyme

704864 Macaca mulatta
100101589 Oryctolagus cuniculus
837 Homo sapiens
12363 Mus musculus
114555 Rattus norvegicus
403724 Canis lupus familiaris
338039 Bos taurus
100359184 Oryctolagus cuniculus
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