BCL2L1 Proteine (BCL2L1)

Bezeichnung:
BCL2-Like 1 Proteine (BCL2L1)
Auf www.antikoerper-online.de finden Sie aktuell 17 BCL2-Like 1 (BCL2L1) Proteine von 9 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen BCL2L1 Antikörper (516) und BCL2L1 Kits (22) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 579 BCL2L1 Produkte verfügbar.
Synonyme:
Bcl(X)L, bcl-X, bcl-x(l), bcl-xl, BCL-XL/S, Bcl-Xs, Bcl2l, BCL2L1, Bclx, BCLXL, BCLXS, PPP1R52, xR11
alle Proteine anzeigen Gen GeneID UniProt
BCL2L1 60480  
BCL2L1 598 Q07817
BCL2L1 24888 P53563

Weitere Synonyme anzeigen

BCL2L1 Proteine (BCL2L1) nach Spezies

Wählen Sie die gewünschte Spezies

Am meisten referenzierte BCL2L1 Proteine

  1. Human BCL2L1 Protein expressed in Escherichia coli (E. coli) - ABIN2180640 : Terrano, Upreti, Chambers: Cyclin-dependent kinase 1-mediated Bcl-xL/Bcl-2 phosphorylation acts as a functional link coupling mitotic arrest and apoptosis. in Molecular and cellular biology 2010 (PubMed)

  2. Mouse (Murine) BCL2L1 Protein expressed in Escherichia coli (E. coli) - ABIN2007143 : Muchmore, Sattler, Liang, Meadows, Harlan, Yoon, Nettesheim, Chang, Thompson, Wong, Ng, Fesik: X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death. in Nature 1996 (PubMed)

Weitere Proteine zu BCL2L1 Interaktionspartnern

Mouse (Murine) BCL2-Like 1 (BCL2L1) Interaktionspartner

  1. Bcl-xL is a driver in colorectal tumorigenesis and cancer progression.

  2. These data show that Mcl-1 (zeige MCL1 Proteine) is dispensable for the regulation of apoptosis during infection with different large DNA viruses.Bcl-XL, on the other hand, can be important to maintain survival of virus-infected cells

  3. BCL-XL expression promotes survival of immature B cells, expression of BCL-2 (zeige BCL2 Proteine) is important for survival of mature B cells and long-lived plasma cells (PC), and expression of MCL-1 (zeige MCL1 Proteine) is important for survival throughout B-cell development.

  4. Bcl-xL deficiency induced apoptosis in a select population of differentiated neurons and led to severe neurobehavioral abnormalities.

  5. loss of PUMA (zeige BBC3 Proteine) had no impact on the loss of platelets caused by loss of BCL-XL. It therefore remains to be established whether other BH3-only (zeige BBC3 Proteine) proteins play a critical role in induction of apoptosis in platelets or whether their death is controlled solely by the interactions between BCL-XL with BAK (zeige BAK1 Proteine) and BAX (zeige BAX Proteine).

  6. MLF1 (zeige MLF1 Proteine) is negatively regulated by 14-3-3 (zeige YWHAQ Proteine) via binding to, and blocking, MLF1 (zeige MLF1 Proteine)'s Bcl-2 (zeige BCL2 Proteine) homology domain 3 and thereby preventing Bcl-XL from associating with MLF1 (zeige MLF1 Proteine).

  7. Genetic and pharmacological inhibition of BCL-W (zeige BCL2L2 Proteine) and BCL-XL causes directed elimination of senescent cells.

  8. Valproic acid sensitized TRAIL-resistant papillary thyroid carcinoma cells to apoptotic cell death through involvement of Nrf2 (zeige NFE2L2 Proteine) and Bcl-xL.

  9. The influence of chronic ethanol consumption on the expression of the Bdnf (zeige BDNF Proteine), Bax (zeige BAX Proteine), Bcl-xL, and CASP3 (zeige CASP3 Proteine) genes was studied in the brain structures of B6-1473C (C/C) and B6-1473G (G/G) mice that had been obtained on the base of the C57BL/6 strain.

  10. despite its role in Bax (zeige BAX Proteine) inhibition, Bcl-xL also primes mitochondria to permeabilization and cytochrome c (zeige CYCS Proteine) release.

Human BCL2-Like 1 (BCL2L1) Interaktionspartner

  1. Bcl-xL is a driver in colorectal tumorigenesis and cancer progression.

  2. These data show that Mcl-1 (zeige MCL1 Proteine) is dispensable for the regulation of apoptosis during infection with different large DNA viruses.Bcl-XL, on the other hand, can be important to maintain survival of virus-infected cells

  3. BC200 knockout suppresses tumor cell growth in vitro and in vivo by expression of the pro-apoptotic Bcl-xS isoform.

  4. Bcl-xL inhibits GAS-induced autophagy directly by suppressing autophagosome-lysosome fusion and indirectly by suppressing GAS internalization via interaction with Beclin 1 (zeige BECN1 Proteine)-UVRAG (zeige UVRAG Proteine).

  5. The combination of 2-deoxyglucose (2-DG) and ABT-199 initiated cell death through the reduction of myeloid cell leukemia sequence 1 protein (Mcl-1 (zeige MCL1 Proteine)) expression and c-Jun N-terminal kinase 1 (JNK1 (zeige MAPK8 Proteine)) activation and subsequent Bcl-xL protein degradation.

  6. Bcl-xL is an exosomal caspase-3 (zeige CASP3 Proteine) substrate and that this processing is required for the uptake of exosomes by recipient cells.

  7. dynamic Bcl-xL(S49) and (S62) phosphorylation/dephosphorylation cycles are important in the maintenance of chromosome integrity during mitosis in normal cells

  8. in addition to MCL-1 (zeige MCL1 Proteine), BCL-XL is heterogeneously expressed in HMCLs and patient samples. The expression profile of BCL-XL relative to BCL-2 (zeige BCL2 Proteine) and MCL-1 (zeige MCL1 Proteine) may be an important predictor of response to venetoclax sensitivity as a monotherapy and in combination with bortezomib.

  9. Mono treatment with lexatumumab was not sufficient to induce apoptosis in pancreatic cancer cells, whereas focal adhesion kinase inhibitor PF573228 significantly sensitized lexatumumab-induced apoptosis. Western blotting analysis revealed that lexatumumab and PF573228 combination treatment increased death receptor 5 (zeige TNFRSF10B Proteine) but decreased Bcl-xL expression.

  10. Reduced lifetimes of the donor were partially restored by coexpression of HIF-1alpha (zeige HIF1A Proteine) or Bcl-xL, binding proteins of IPAS (zeige HIF3A Proteine) in the nucleus and mitochondria, respectively.

Pig (Porcine) BCL2-Like 1 (BCL2L1) Interaktionspartner

  1. interleukin-6 (zeige IL6 Proteine), endothelin ET-1 (zeige EDN1 Proteine), and apoptotic Bak (zeige BAK1 Proteine) and Bcl-XL genes have roles in small bowel transplantation, in a swine model of ischemia and reperfusion injury

  2. Bcl-xL was significantly decreased in haploid parthenotes compared with the diploid parthenotes. These results suggest that the haploid state affects apoptosis-related gene expression which results in increased apoptosis

  3. CONCLUSION(S): (1) Apoptosis is involved in follicular atresia; (2) Bcl-2 (zeige BCL2 Proteine) is induced by warm ischemia; and (3) cryopreservation insult does not alter the apoptotic signals with short tissue preparation time.

  4. Bcl-Xl deamidation and methylation has a role in protein isoaspartate methyltransferase prevention of apoptosis induced by oxidative stress in endothelial cells

  5. Data show that cysteine significantly reduced the expression of pro-inflammatory cytokines, including TNF-alpha (zeige TNF Proteine), IL-6 (zeige IL6 Proteine), IL-12p40, IL-1beta (zeige IL1B Proteine), and resulted in increased expression of the apoptosis initiator caspase-8 (zeige CASP8 Proteine) and bcl2L1.

Cow (Bovine) BCL2-Like 1 (BCL2L1) Interaktionspartner

  1. amplification and characterization of partial regions of exons 2 and 3 of the bovine BCL2L1 gene

  2. Data show that Bcl-x(L) expression is increased in the pulmonary artery undergoing chronic pulmonary vascular remodeling.

Rabbit BCL2-Like 1 (BCL2L1) Interaktionspartner

  1. This study leads to conclude that BCLXL peak expression at the zygotic genome activation phase may be a requirement for embryo development

  2. In this study evidence is provided that exogenous PGF2alpha differentially modulates luteal expression of BCL2L1 transcripts and protein depending on luteal stage.

Xenopus laevis BCL2-Like 1 (BCL2L1) Interaktionspartner

  1. repression of radiation-induced apoptosis by overexpression of Bcl-xL during embryonic development depends upon the timing of its expression and post-translational events that enable the protein to become effective

BCL2L1 Protein Überblick

Protein Überblick

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator.

Alternative names and synonyms associated with BCL2L1

  • BCL2-like 1 (bcl2l1)
  • BCL2-like 1 (BCL2L1)
  • BCL2-like 1 (LOC100224900)
  • transgene insertion 2, Craig B Thompson (Tg(BCL2L1)2Cbt)
  • BCL2-like 1 (Bcl2l1)
  • Bcl2-like 1 (Bcl2l1)
  • Bcl(X)L Protein
  • bcl-X Protein
  • bcl-x(l) Protein
  • bcl-xl Protein
  • BCL-XL/S Protein
  • Bcl-Xs Protein
  • Bcl2l Protein
  • BCL2L1 Protein
  • Bclx Protein
  • BCLXL Protein
  • BCLXS Protein
  • PPP1R52 Protein
  • xR11 Protein

Bezeichner auf Proteinebene für BCL2-Like 1 Proteine (BCL2L1)

BCL2-like 1 , apoptosis regulator Bcl-X , bcl-2-like protein 1 , protein phosphatase 1, regulatory subunit 52 , B-cell leukemia/lymphoma x , anti-apoptosis regulatory protein , bcl2-L-1 , B cell lymphoma 2 like , B cell lymphoma like X , anti-apoptotic Bcl-xL , BCL2-like protein 1 , Bcl-X , BCLX protein , apoptosis regulator R11

GENE ID SPEZIES
447991 Xenopus (Silurana) tropicalis
458156 Pan troglodytes
100224900 Taeniopygia guttata
60480 Mus musculus
598 Homo sapiens
12048 Mus musculus
24888 Rattus norvegicus
397536 Sus scrofa
403618 Canis lupus familiaris
282152 Bos taurus
100008875 Oryctolagus cuniculus
493701 Felis catus
443061 Ovis aries
373954 Gallus gallus
398251 Xenopus laevis
Ausgewählte Anbieter für BCL2L1 Proteine (BCL2L1)
Haben Sie etwas anderes gesucht?