anti-AIFM1 (AIFM1) Antikörper

Auf www.antikoerper-online.de finden Sie aktuell 181 Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) Antikörper von 31 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen AIFM1 Proteine (15) und AIFM1 Kits (12) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 227 AIFM1 Produkte verfügbar.
Synonyme:
Aif, AIFM1, AIFsh2, CG7263, CMTX4, COWCK, COXPD6, DDBDRAFT_0187853, DDBDRAFT_0191137, DDB_0187853, DDB_0191137, DmAIF, Dmel\\CG7263, GB16024, Hq, mAIF, PCD8, Pdcd8, zgc:91994
Alle Antikörper anzeigen Gen GeneID UniProt
AIFM1 26926 Q9Z0X1
AIFM1 83533 Q9JM53
AIFM1 9131 O95831

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Weitere Antikörper gegen AIFM1 Interaktionspartner

Pig (Porcine) Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) Interaktionspartner

  1. Mitochondrial apoptosis-inducing factor was found to translocate to the nucleus during porcine epidemic diarrhea virus infection.

Fruit Fly (Drosophila melanogaster) Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) Interaktionspartner

  1. Drosophila Apoptosis-inducing factor (AIF) is a mitochondrial effector of cell death that plays roles in developmentally regulated cell death and normal mitochondrial function.

Cow (Bovine) Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) Interaktionspartner

  1. apoptosis-inducing factor(AIF) was expressed in luminal alveolar cells and in concert with a change in bax (zeige BAX Antikörper) protein to bcl-2 (zeige BCL2 Antikörper) protein ratio might contribute to signalling of a change in the dynamic balance of the cell population as lactation progresses(AIF)

  2. Mycobacterium bovis-induced macrophage cell death is caspase (zeige CASP3 Antikörper) independent with apoptosis-inducing factor participation.

Mouse (Murine) Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) Interaktionspartner

  1. X-ray irradiation induces apoptosis of mouse GC1 sperm cells via nuclear translocation of AIF.

  2. The first structure of a pathogenic AIF variant in complex with NAD+ is reported. The G307E mutation leads to wrong positioning of NAD+ adenylate moiety.

  3. AIF deficiency is a risk factor for the development of diabetic kidney disease.

  4. In conclusion, calpain was involved in oxygen glucose deprivation-induced RGC-5 necroptosis with the increased expression of its downstream molecule tAIF.

  5. The results identify new protein-protein interactions between AIF-Cx43 (zeige GJA1 Antikörper), ETFB (zeige ETFB Antikörper)-Cx43 (zeige GJA1 Antikörper) and AIF-ETFB (zeige ETFB Antikörper) as possible players in the regulation of the mitochondrial redox state.

  6. our findings suggest that MIA40 (zeige CHCHD4 Antikörper) reduction contributes to the effects of AIF deficiency on OXPHOS, as it may impact on the correct assembly and maintenance of the respiratory subunits.

  7. These results indicate that the adenylate moiety of NAD(+)/H is crucial for the association with AIF and for the subsequent structural reorganization of the complex, but not for protein dimerization.

  8. Taken together, these data suggest that AIF is likely to play a region-specific role in AD-related caspase (zeige CASP3 Antikörper)-independent PCD (zeige PCBD1 Antikörper), which is consistent with aging-associated mitochondrial impairment and oxidative stress.

  9. findings postulate that AIF depletion mediates a preconditioning effect protecting neuronal cells from subsequent glutamate (zeige GRIN1 Antikörper) toxicity through reduced levels of complex I protein

  10. AIF downregulation provides not only long-term overall neuroprotection after hypoxia-ischemia, but also protects neural progenitor cells, thereby rescuing hippocampal neurogenesis.

Human Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) Interaktionspartner

  1. Downregulation of AIF by hypoxia causes oxidative inactivation of the lipid phosphatase activity of phosphatase and tensin homolog (zeige PTEN Antikörper) on chromosome 10 (PTEN (zeige PTEN Antikörper)), with ensuing activation of Akt (zeige AKT1 Antikörper) kinase, phosphorylation of the Akt (zeige AKT1 Antikörper) substrate GSK-3beta (zeige GSK3b Antikörper) and activation of WNT (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) signaling in colon cancer cells.

  2. novel pathway for mda-7/IL-24 (zeige IL24 Antikörper)-induced caspase (zeige CASP3 Antikörper)-independent apoptosis in neuroblastoma (zeige ARHGEF16 Antikörper) cells mediated through modulation of AIF, ATM (zeige ATM Antikörper), and gamma-H2AX (zeige H2AFX Antikörper).

  3. Study defines the mechanism whereby AIF is allosterically modulated by charge-complex formation with NADH. Two distinct molecular pathways couple AIF's active site to dimerization and release of its regulatory C-loop insert with implications for AIF allosteric switching in cell survival and death.

  4. Whole exome sequencing indicated a single plausible candidate - the p.Asp237Gly variant in apoptosis inducing factor mitochondria associated 1 (AIFM1; chr. Xq26.1), and the p.Asp237Gly segregated with disease in two families.

  5. Only a drastic decrease in the expression level or/and redox activity of AIF tends to cause an early and severe neurodegeneration, whereas less pronounced changes in the AIF properties could lead to a broad range of slowly progressive neurological disorders.

  6. AIF translocation plays a role in influenza-virus-induced apoptosis.

  7. Copper induces the activation of apoptosis through casp3 (zeige CASP3 Antikörper)/casp8 (zeige CASP8 Antikörper)/casp9 (zeige CASP9 Antikörper)/AIF/TP53 (zeige TP53 Antikörper) signaling pathways. Suggest that apoptosis activation mechanism is dependent on the concentration, time of exposure to Cu and cell type.

  8. Estradiol inhibits oxidative stress-induced (zeige SQSTM1 Antikörper) accumulation of AIF in nucleolus and PARP1 (zeige PARP1 Antikörper)-dependent cell death via estrogen receptor alpha (zeige ESR1 Antikörper) in MCF-7 cells.

  9. AIF may participate in but not be dominant in the process of retinal pigment epithelium cell apoptosis induced by oxidative stress.

  10. Altogether these data indicate that AIF supports the growth and survival of metabolically defined pancreatic cancer cells and that this metabolic function may derive from a novel mechanism so far undocumented in other cancer types.

AIFM1 Antigen-Profil

Beschreibung des Gens

This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10.

Alternative names and synonyms associated with AIFM1

  • apoptosis-inducing factor, mitochondrion-associated, 1 (aifm1) Antikörper
  • apoptosis-inducing factor, mitochondrion-associated, 1 (AIFM1) Antikörper
  • Apoptosis inducing factor (AIF) Antikörper
  • apoptosis inducing factor (AIF) Antikörper
  • apoptosis inducing factor (aif) Antikörper
  • allograft inflammatory factor 1 (AIF1) Antikörper
  • apoptosis-inducing factor, mitochondrion-associated 1 (Aifm1) Antikörper
  • apoptosis-inducing factor, mitochondrion-associated 1 (aifm1) Antikörper
  • Aif Antikörper
  • AIFM1 Antikörper
  • AIFsh2 Antikörper
  • CG7263 Antikörper
  • CMTX4 Antikörper
  • COWCK Antikörper
  • COXPD6 Antikörper
  • DDBDRAFT_0187853 Antikörper
  • DDBDRAFT_0191137 Antikörper
  • DDB_0187853 Antikörper
  • DDB_0191137 Antikörper
  • DmAIF Antikörper
  • Dmel\\CG7263 Antikörper
  • GB16024 Antikörper
  • Hq Antikörper
  • mAIF Antikörper
  • PCD8 Antikörper
  • Pdcd8 Antikörper
  • zgc:91994 Antikörper

Bezeichner auf Proteinebene für AIFM1

programmed cell death 8 (apoptosis-inducing factor) , programmed cell death 8 , apoptosis-inducing factor, mitochondrion-associated, 1 , mammary apoptosis inducing factor , flavoprotein and apoptosis inductor , apoptosis-inducing factor 1, mitochondrial-like , AIF-PA , AIF-PB , AIF-PC , CG7263-PA , CG7263-PB , CG7263-PC , apoptosis inducing factor , AIF-1 , anti-inflammatory factor 1 , apoptosis-inducing factor 1, mitochondrial , harlequin , programmed cell death protein 8 , striatal apoptosis-inducing factor

GENE ID SPEZIES
549998 Xenopus (Silurana) tropicalis
768258 Felis catus
100054546 Equus caballus
100188912 Ovis aries
100387002 Callithrix jacchus
100471854 Ailuropoda melanoleuca
100524062 Sus scrofa
100562576 Anolis carolinensis
100605967 Nomascus leucogenys
100615914 Pan troglodytes
33390 Drosophila melanogaster
412212 Apis mellifera
8626532 Dictyostelium discoideum AX4
280989 Bos taurus
26926 Mus musculus
83533 Rattus norvegicus
373125 Danio rerio
9131 Homo sapiens
428688 Gallus gallus
481048 Canis lupus familiaris
535714 Bos taurus
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