anti-HCK (HCK) Antikörper

Bezeichnung:
anti-Hemopoietic Cell Kinase Antikörper (HCK)
Auf www.antikoerper-online.de finden Sie aktuell 146 Hemopoietic Cell Kinase (HCK) Antikörper von 19 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen HCK Proteine (16) und HCK Kits (8) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 183 HCK Produkte verfügbar.
Synonyme:
AI849071, Bmk, HCK, Hctk, JTK9, laloo, MGC107870, p56Hck, p59Hck, p61Hck

Meistgesuchte Reaktivitäten zu anti-HCK (HCK) Antikörper

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anti-Human HCK Antikörper:

anti-Mouse (Murine) HCK Antikörper:

anti-Rat (Rattus) HCK Antikörper:

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Am meisten referenzierte anti-HCK Antikörper

  1. Dog (Canine) Monoclonal HCK Primary Antibody für IF, IP - ABIN967877 : Baumgartner, Angelisová, Setterblad, Mooney, Werling, Horejsí, Langsley: Constitutive exclusion of Csk from Hck-positive membrane microdomains permits Src kinase-dependent proliferation of Theileria-transformed B lymphocytes. in Blood 2003 (PubMed)
    Zeige alle 5 Referenzen für 967877

  2. Human Polyclonal HCK Primary Antibody für EIA, WB - ABIN359984 : Komuro, Yokota, Yasuda, Iwamoto, Kagawa: CSF-induced and HIV-1-mediated distinct regulation of Hck and C/EBPbeta represent a heterogeneous susceptibility of monocyte-derived macrophages to M-tropic HIV-1 infection. in The Journal of experimental medicine 2003 (PubMed)
    Zeige alle 4 Referenzen für 359984

  3. Human Polyclonal HCK Primary Antibody für FACS, IHC (p) - ABIN652384 : Hassan, Suzu, Hiyoshi, Takahashi-Makise, Ueno, Agatsuma, Akari, Komano, Takebe, Motoyoshi, Okada: Dys-regulated activation of a Src tyroine kinase Hck at the Golgi disturbs N-glycosylation of a cytokine receptor Fms. in Journal of cellular physiology 2009 (PubMed)
    Zeige alle 3 Referenzen für 652384

  4. Human Polyclonal HCK Primary Antibody für IF, ELISA - ABIN1531606 : Deloukas, Matthews, Ashurst, Burton, Gilbert, Jones, Stavrides, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beard, Beare, Beasley, Bird, Blakey, Bridgeman, Brown, Buck, Burrill, Butler, Carder et al.: The DNA sequence and comparative analysis of human chromosome 20. ... in Nature 2002 (PubMed)
    Zeige alle 2 Referenzen für 1531606

  5. Human Polyclonal HCK Primary Antibody für WB - ABIN392099 : Stanglmaier, Warmuth, Kleinlein, Reis, Hallek: The interaction of the Bcr-Abl tyrosine kinase with the Src kinase Hck is mediated by multiple binding domains. in Leukemia 2003 (PubMed)
    Zeige alle 2 Referenzen für 392099

  6. Human Monoclonal HCK Primary Antibody für IHC, ELISA - ABIN969187 : Schnoor: What I learned in Europe.... in Environmental science & technology 2007 (PubMed)
    Zeige alle 2 Referenzen für 969187

Weitere Antikörper gegen HCK Interaktionspartner

Human Hemopoietic Cell Kinase (HCK) Interaktionspartner

  1. Lysophosphatidylcholines prime polymorphonuclear neutrophil through Hck-dependent activation of PKCdelta (zeige PKCd Antikörper), which stimulates PKCgamma (zeige PRKCG Antikörper), resulting in translocation of phosphorylated p47(phox).

  2. HCK represents a novel target for therapeutic development in MYD88 (zeige MYD88 Antikörper)-mutated Waldenstrom macroglobulinemia and activated-B cell diffuse large B-cell lymphoma, and possibly other diseases driven by mutated MYD88 (zeige MYD88 Antikörper).

  3. High HCK levels correlate with reduced survival of colorectal cancer patients and is associated with activated macrophages gene signature.

  4. three-dimensional (3D) QSAR pharmacophore models were generated for Hck based on experimentally known inhibitors. A best pharmacophore model, Hypo1, was developed with high correlation coefficient (0.975), Low RMS deviation (0.60) and large cost difference (49.31), containing three ring aromatic and one hydrophobic aliphatic feature

  5. we provide evidence for involvement of HCK and FGR (zeige FGR Antikörper) in FCRL4 (zeige FCRL4 Antikörper)-mediated immunoregulation and for the functional importance of posttranslational modifications of the FCRL4 (zeige FCRL4 Antikörper) molecule.

  6. Interaction with the Src (zeige SRC Antikörper) homology (SH3-SH2) region of the Hck structures the HIV-1 Nef dimer for kinase activation and effector recruitment.

  7. Interaction between Nef and Hck is important for Nef-dependent modulation of viral infectivity.

  8. Data indicate that combined treatment using SFK (LYN (zeige LYN Antikörper), HCK, or FGR (zeige FGR Antikörper)) and c-KIT (zeige KIT Antikörper) inhibitor dasatinib dasatinib and chemotherapy provides a novel approach to increasing p53 (zeige TP53 Antikörper) activity and enhancing targeting of acute myeloid leukemia (zeige BCL11A Antikörper) (AML (zeige RUNX1 Antikörper)) stem cells.

  9. The SRC (zeige SRC Antikörper) family tyrosine kinase (zeige TXK Antikörper) HCK and the ETS (zeige ETS1 Antikörper) family transcription factors SPIB (zeige SPIB Antikörper) and EHF (zeige EHF Antikörper) regulate transcytosis across a human follicle-associated epithelium model.

  10. This particular binding mode enables Hck SH3 to sense a specific non-canonical residue situated in the SH3 RT-loop of the kinase.

Mouse (Murine) Hemopoietic Cell Kinase (HCK) Interaktionspartner

  1. the Hck, Fgr (zeige FGR Antikörper) and Lyn (zeige LYN Antikörper) kinases are also necessary for amastigote uptake by macrophages. Src (zeige SRC Antikörper)-mediated Arg activation is required for efficient uptake.

  2. Hematopoietic Hck promotes tumorigenesis.

  3. Data suggest that Hck is a key mediator of renal fibrosis

  4. Data indicate that Src (zeige SRC Antikörper)-Family Kinases Hck and Fgr (zeige FGR Antikörper) regulate cytokine secretion by macrophages.

  5. Hck is not only progressively overexpressed in atherosclerosis, but it also controls critical molecular processes in monocyte influx, blood monocyte subset balance, macrophage accumulation, and the maintenance of atherosclerotic lesion stability.

  6. The Src (zeige SRC Antikörper) family kinases Hck, Fgr (zeige FGR Antikörper), and Lyn (zeige LYN Antikörper) are critical for the generation of the in vivo inflammatory environment without a direct role in leukocyte recruitment.

  7. tyrosine phosphorylation of WASP (zeige WASL Antikörper) by Hck is required for proper macrophage functions

  8. Hck is one of the very few effectors of preosteoclast recruitment described to date and thereby plays a critical role in bone remodeling.

  9. Despite possessing enhanced killing, alveolar macrophage Hck/Fgr (zeige FGR Antikörper)/Lyn (zeige LYN Antikörper)-deficient ("triple-knockout") mice do not demonstrate enhanced inflammatory responses to Pneumocystis murina.

  10. Taken together, PKR (zeige EIF2AK2 Antikörper) and Hck were critical for DON-induced ribosomal recruitment of p38 (zeige CRK Antikörper), its subsequent phosphorylation, and, ultimately, p38 (zeige CRK Antikörper)-driven proinflammatory cytokine expression.

Cow (Bovine) Hemopoietic Cell Kinase (HCK) Interaktionspartner

  1. A truncated, mRNA-encoded src-related tyrosine kinase (zeige FRK Antikörper) HCK could function as an adaptor protein or as a competitive inhibitor in spermiogenesis or mature sperm functions.

  2. the presence of mRNAs encoding for hck and hck-tr in testicular germ cells; hck-tr being translated during spermatogenesis and expressed on mature ejaculated bull spermatozoa.

HCK Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon.

Alternative names and synonyms associated with HCK

  • hemopoietic cell kinase (tklal-a) Antikörper
  • hemopoietic cell kinase (HCK) Antikörper
  • hemopoietic cell kinase (hck) Antikörper
  • hemopoietic cell kinase (Hck) Antikörper
  • AI849071 Antikörper
  • Bmk Antikörper
  • HCK Antikörper
  • Hctk Antikörper
  • JTK9 Antikörper
  • laloo Antikörper
  • MGC107870 Antikörper
  • p56Hck Antikörper
  • p59Hck Antikörper
  • p61Hck Antikörper

Bezeichner auf Proteinebene für HCK

hemopoietic cell kinase , non-receptor protein tyrosine kinase laloo , tyrosine-protein kinase HCK-like , hematopoietic cell kinase , p59-HCK/p60-HCK , tyrosine-protein kinase HCK , B cell/myeloid kinase , B-cell/myeloid kinase , p56-HCK/p59-HCK , hemopoietic cell tyrosine kinase , p56-HCK

GENE ID SPEZIES
373700 Xenopus laevis
458163 Pan troglodytes
485828 Canis lupus familiaris
548439 Xenopus (Silurana) tropicalis
100455620 Pongo abelii
100587780 Nomascus leucogenys
3055 Homo sapiens
15162 Mus musculus
25734 Rattus norvegicus
419280 Gallus gallus
280814 Bos taurus
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