anti-DDX58 (DDX58) Antikörper

anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 Antikörper (DDX58)
Auf finden Sie aktuell 179 DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) Antikörper von 26 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen DDX58 Proteine (12) und DDX58 Kits (9) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 206 DDX58 Produkte verfügbar.
6430573D20Rik, C330021E21, RHIV-1, RIG-1, RIG-I, RIGI, RLR-1
Alle Antikörper anzeigen Gen GeneID UniProt
DDX58 23586 O95786
DDX58 230073 Q6Q899
DDX58 297989  

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Meistgesuchte Reaktivitäten zu anti-DDX58 (DDX58) Antikörper

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anti-Human DDX58 Antikörper:

anti-Mouse (Murine) DDX58 Antikörper:

anti-Rat (Rattus) DDX58 Antikörper:

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Am meisten referenzierte anti-DDX58 Antikörper

  1. Human Polyclonal DDX58 Primary Antibody für WB - ABIN388602 : Bao, Liu, Shan, Li, Garofalo, Casola: Human metapneumovirus glycoprotein G inhibits innate immune responses. in PLoS pathogens 2008 (PubMed)
    Zeige alle 9 Referenzen für 388602

  2. Human Polyclonal DDX58 Primary Antibody für EIA, WB - ABIN357193 : Li, Chen, Kato, Gale, Lemon: Distinct poly(I-C) and virus-activated signaling pathways leading to interferon-beta production in hepatocytes. in The Journal of biological chemistry 2005 (PubMed)
    Zeige alle 5 Referenzen für 357193

  3. Human Polyclonal DDX58 Primary Antibody für EIA, WB - ABIN357195 : Breiman, Grandvaux, Lin, Ottone, Akira, Yoneyama, Fujita, Hiscott, Meurs: Inhibition of RIG-I-dependent signaling to the interferon pathway during hepatitis C virus expression and restoration of signaling by IKKepsilon. in Journal of virology 2005 (PubMed)
    Zeige alle 5 Referenzen für 357195

  4. Human Monoclonal DDX58 Primary Antibody für IP, IHC - ABIN1169336 : Gack, Nistal-Villán, Inn, García-Sastre, Jung: Phosphorylation-mediated negative regulation of RIG-I antiviral activity. in Journal of virology 2010 (PubMed)
    Zeige alle 4 Referenzen für 1169336

  5. Human Polyclonal DDX58 Primary Antibody für ELISA, IHC - ABIN4350536 : Zhu, Duan, Wang, Cao, Liu: TREM-1 activation modulates dsRNA induced antiviral immunity with specific enhancement of MAPK signaling and the RLRs and TLRs on macrophages. in Experimental cell research 2016 (PubMed)

  6. Horse (Equine) Polyclonal DDX58 Primary Antibody für WB - ABIN2775222 : Miyazaki, Kanto, Inoue, Itose, Miyatake, Sakakibara, Yakushijin, Kakita, Hiramatsu, Takehara, Kasahara, Hayashi: Impaired cytokine response in myeloid dendritic cells in chronic hepatitis C virus infection regardless of enhanced expression of Toll-like receptors and retinoic acid inducible gene-I. in Journal of medical virology 2008 (PubMed)

  7. Human Polyclonal DDX58 Primary Antibody für IHC (p), WB - ABIN4350540 : Seki, Yoshizumi, Tanaka, Ryo, Ishioka, Tsukagoshi, Kozawa, Okayama, Okabe-Kado, Goya, Kimura: Cytokine profiles, signalling pathways and effects of fluticasone propionate in respiratory syncytial virus-infected human foetal lung fibroblasts. in Cell biology international 2014 (PubMed)

  8. Human Monoclonal DDX58 Primary Antibody für IHC, IHC (p) - ABIN4350538 : Pei, Deng, Ye, Wang, Gou, Liu, Zhao, Liao, Yi, Chen: Absence of autophagy promotes apoptosis by modulating the ROS-dependent RLR signaling pathway in classical swine fever virus-infected cells. in Autophagy 2016 (PubMed)

Weitere Antikörper gegen DDX58 Interaktionspartner

Human DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) Interaktionspartner

  1. These data suggest that prior exposure to IFN-gamma (zeige IFNG Antikörper) may leave an epigenetic mark on the chromatin that enhances airway cells' ability to resist infection, possibly via epigenetic upregulation of RIG-I.

  2. findings show that RIG-I and MDA5 (zeige IFIH1 Antikörper) triggering by dengue virus leads to TH1 (zeige TH1L Antikörper) polarization, which is characterized by high levels of IFN-gamma (zeige IFNG Antikörper); identified RIG-I and MDA5 (zeige IFIH1 Antikörper) as critical players in innate and adaptive immune responses against Dengue virus

  3. Results identified a negative-feedback mechanism that targets RIG-I activity mediated by DAPK1 (zeige DAPK1 Antikörper). RIG-I-mediated antiviral signaling activates DAPK1 (zeige DAPK1 Antikörper) kinase activity and DAPK1 (zeige DAPK1 Antikörper) inactivates RIG-I RNA sensing by direct phosphorylation of RIG-I.

  4. Mechanistically, West Nile virus NS1 (zeige PTPN11 Antikörper) targets RIG-I and melanoma differentiation-associated gene 5 (MDA5 (zeige IFIH1 Antikörper)) by interacting with them and subsequently causing their degradation by the proteasome.

  5. RIG-I stimulates the cellular innate immunity against hepatitis E virus infections.

  6. dynamic sumoylation and desumoylation of MDA5 (zeige IFIH1 Antikörper) and RIG-I modulate efficient innate immunity to RNA virus and its timely termination.

  7. Taken together, the present study reveals that T80 phosphorylation of influenza A virus NS1 reduced virus replication through controlling RIG-I-mediated interferon production and viral ribonucleoprotein activity.

  8. results suggest that RNAs containing modified nucleotides interrupt signaling at early steps of the RIG-I-like innate immune activation pathway

  9. The authors found that in Sendai virus C protein deletion mutant-infected cells, Sendai virus defective interfering RNA also functioned as an exclusive RIG-I ligand.

  10. ArfGAP domain-containing protein 2 (ADAP2 (zeige ADAP2 Antikörper)) is identified as a key novel scaffolding protein that integrates different modules of the RIG-I pathway, located at distinct subcellular locations, and mediates cellular antiviral type I interferon (zeige IFNA Antikörper) production.

Mouse (Murine) DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) Interaktionspartner

  1. Collectively, these results uncover an independent functional contribution of the apo (zeige C9orf3 Antikörper)-Rig-I/Stat3 (zeige STAT3 Antikörper) interaction in the maintenance of Treg/Th17 cell balance.

  2. The RIG-I, as well as the adaptor protein mitochondrial antiviral signaling protein (zeige MAVS Antikörper), regulates NF-kappaB (zeige NFKB1 Antikörper)-mediated induction of adhesion molecules and proinflammatory cytokine expression in response to LPS (zeige TLR4 Antikörper).

  3. Data suggest that activation of either RIG-I/MAVS (zeige MAVS Antikörper) or STING pathways during acute intestinal tissue injury in mice resulted in IFN-I signaling that maintained gut (zeige GUSB Antikörper) epithelial barrier integrity and reduced GVHD severity.

  4. RIG-I subsequently localized to antiviral stress granules induced after viral replication complexes formation

  5. identifies DDX58 and MTHFSD as two TDP-43 (zeige TARDBP Antikörper) targets that are misregulated in amyotrophic lateral sclerosis. 1

  6. Data show that preconditioning with poly(I:C) alters toll (zeige TLR4 Antikörper)-like receptors (TLR) and RIG-I-like receptors (RLRs) responses in opposite directions.

  7. Cytosolic LMW FGF2 (zeige FGF2 Antikörper) functions as a negative regulator in RIG-I-mediated antiviral signaling.

  8. results indicate that Lyn (zeige LYN Antikörper) plays a positive regulatory role in RIG-I-mediated interferon (zeige IFNA Antikörper) expression as a downstream component of IPS-1 (zeige ISYNA1 Antikörper)

  9. In lung epithelial cells, retinoic acid-inducible gene-1 (zeige RARRES3 Antikörper) (RIG-I) was identified as the major RIG-I-like receptor required for RSV-induced protease expression via MAVS (zeige MAVS Antikörper).

  10. findings suggest that RIG-I directs a typical IFN-dependent antiviral response against an RNA virus capable of suppressing the RNAi response

Pig (Porcine) DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) Interaktionspartner

  1. Viral RNA polymerase components PB2, PB1, and PA directly target RIG-I.

  2. These data indicate that classical swine fever virus can be recognized by both RIG-I and MDA5 (zeige IFIH1 Antikörper) to initiate the RIG-I signaling pathway to trigger innate defenses against infection.

  3. DDX58 had two nonsynonymous SNPs in the helicase (zeige DNA2 Antikörper) domain.

DDX58 Antigen-Profil

Beschreibung des Gens

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of immune response.

Alternative names and synonyms associated with DDX58

  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 (DDX58) Antikörper
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 (Ddx58) Antikörper
  • 6430573D20Rik Antikörper
  • C330021E21 Antikörper
  • RHIV-1 Antikörper
  • RIG-1 Antikörper
  • RIG-I Antikörper
  • RIGI Antikörper
  • RLR-1 Antikörper

Bezeichner auf Proteinebene für DDX58

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide RIG-I , probable ATP-dependent RNA helicase DDX58 , putative ATP-dependent RNA helicase DDX58 , retinoic acid-inducible protein I , DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 , probable ATP-dependent RNA helicase DDX58-like , DEAD box protein 58 , DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide , RIG-1 , RIG-I-like receptor 1 , RNA helicase RIG-I , retinoic acid inducible gene I , retinoic acid-inducible gene 1 protein , retinoic acid-inducible gene I protein , DEAD-box protein 58 , DEAD/H box polypeptide RIG-I , retinoic acid-inducible gene-I , RNA helicase induced by virus

465035 Pan troglodytes
704638 Macaca mulatta
100067920 Equus caballus
100347707 Oryctolagus cuniculus
100408692 Callithrix jacchus
100443290 Pongo abelii
23586 Homo sapiens
230073 Mus musculus
297989 Rattus norvegicus
100686785 Canis lupus familiaris
396723 Sus scrofa
504760 Bos taurus
101107257 Ovis aries
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