anti-gamma-Glutamyl Carboxylase (GGCX) Antikörper

GGCX encodes an enzyme which catalyzes the posttranslational modification of vitamin K-dependent protein. Zusätzlich bieten wir Ihnen GGCX Proteine (5) und GGCX Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
GGCX 2677 P38435
GGCX 56316 Q9QYC7
GGCX 81716 O88496
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Top anti-GGCX Antikörper auf antikoerper-online.de

Showing 10 out of 65 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-GGCX Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>MCF7 cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB GGCX Antibody (Center) (ABIN655069) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB Formalin fixed and paraffin embedded human liver tissue reacted with GGCX Antibody (Center) followed by peroxidase conjugation of the secondary antibody and DAB staining. Western blot analysis of GGCX Antibody (Center) in 293 cell line lysates (35ug/lane). This demonstrates the GGCX antibody detected the GGCX protein (arrow). 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Ziege Unkonjugiert ELISA, IHC, WB Western Blot: GGCX Antibody [NBP1-51964] - Analysis of GGCX in Human Muscle lysate (35ug protein in RIPA buffer) using NBP1-51964 at 0.3 ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 2 bis 4 Tage
311,00 €
Details
Hund Ziege Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
357,50 €
Details
Human Ziege Unkonjugiert ELISA, WB 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
505,48 €
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Western Blot: GGCX Antibody [NBP2-16651] - Sample (30 ug of whole cell lysate) A: A431 B: HeLa C: HepG2 7. 5% SDS PAGE gel, diluted at 1:3000. Immunohistochemistry-Paraffin: GGCX Antibody [NBP2-16651] - Immunohistochemical analysis of paraffin-embedded HBL435 xenograft, using antibody at 1:500 dilution. 0.1 mL Anmelden zum Anzeigen 3 bis 6 Tage
341,00 €
Details
Human Kaninchen Unkonjugiert ELISA, WB 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
459,65 €
Details
Human Kaninchen Unkonjugiert WB GGCX antibody used at 1 ug/ml to detect target protein. 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
460,89 €
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GGCX Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-GGCX Antikörper

  1. Human Polyclonal GGCX Primary Antibody für ELISA, IHC - ABIN4314074 : Li, Grange, Armstrong, Whelan, Hurley, Rishavy, Hallgren, Berkner, Schurgers, Jiang, Uitto: Mutations in the GGCX and ABCC6 genes in a family with pseudoxanthoma elasticum-like phenotypes. in The Journal of investigative dermatology 2009 (PubMed)

Weitere Antikörper gegen GGCX Interaktionspartner

Human gamma-Glutamyl Carboxylase (GGCX) Interaktionspartner

  1. impact of CYP4F2 (zeige CYP4F2 Antikörper), ABCB1 (zeige ABCB1 Antikörper), and GGCX polymorphisms on bleeding episodes associated with acenocoumarol in Russian patients with atrial fibrillation

  2. this systematic review suggests that there indeed may be genotype-phenotype correlations for GGCX-related phenotypes, which can guide patient counseling and management.

  3. 529 adults (n = 325 European-Americans, 204 Egyptians) on a stable warfarin dose were genotyped for GGCX rs12714145 and rs10654848, FPGS (zeige FPGS Antikörper) rs7856096, and STX1B (zeige STX1B Antikörper) rs4889606.

  4. GGCX c.2084+45G polymorphisms has a moderate effect on VKAs dose requirements in Slavic population from Central-Eastern Europe.

  5. Detected are ten mutations in the gamma-glutamyl carboxylase gene in patients with hereditary deficiency of vitamin K-dependent coagulation factors.

  6. The allele frequency for GGCX 12970 C > G is 1.43 in north Indians and did not have a significant bearing on the maintenance dose of acenocoumarol oral anticoagulant in cardiac valve replacement patients.

  7. GGCX mutation found in families with pseudoxanthoma elasticum with retinitis pigmentosa and cutis laxa.

  8. These findings indicate that individuals carrying the CYP2C19 (zeige CYP2C19 Antikörper) rs3814637CC or CYP2C9 (zeige CYP2C9 Antikörper) rs1057910AA or GGCX rs699664AA genotype needed higher warfarin doses in the Chinese population.

  9. In atrial fibrillation population in Xinjiang, patients with CT and TT genotypes in the gamma-glutamyl carboxylase gene rs259251 loci required significantly higher warfarin dose than those with CC genotype.

  10. evaluation of urinary Gla (zeige NAT8 Antikörper) excretion in relation with apo E (zeige APOE Antikörper) genotype

Mouse (Murine) gamma-Glutamyl Carboxylase (GGCX) Interaktionspartner

  1. GGCX in osteoblasts functions to prevent abnormal mineralization in bone formation.

  2. findings suggest that GGCX expressed in osteoblasts is critical for the maintenance of blood glucose and WAT

  3. OCN is gamma-carboxylated by the gamma-carboxylase (GGCX) on three glutamic acid residues, a cellular process requiring reduction of vitamin K by a second enzyme, VKORC1 (zeige VKORC1 Antikörper).

  4. Ggcx(Deltaliver/Deltaliver) mice displayed bleeding diathesis.

  5. Effect of vitamin K-dependent protein precursor propeptide, vitamin K hydroquinone, and glutamate (zeige GRIN1 Antikörper) substrate binding on the structure and function of {gamma}-glutamyl carboxylase.

  6. These findings suggest a role for both the GGCX gene and the genetic background as well as dietary factors in modulating the phenotypic severity of Pseudoxanthoma elasticum caused by loss-of-function mutations in ABCC6 (zeige ABCC6 Antikörper).

  7. Analysis of a Ggcx(+/-) intercross revealed a partial developmental block with only 50% of expected Ggcx(-/-) offspring surviving to term, with the latter animals dying uniformly at birth of massive intra-abdominal hemorrhage

GGCX Antigen-Profil

Protein Überblick

This gene encodes an enzyme which catalyzes the posttranslational modification of vitamin K-dependent protein. Many of these vitamin K-dependent proteins are involved in coagulation so the function of the encoded enzyme is essential for hemostasis. Mutations in this gene are associated with vitamin K-dependent coagulation defect and PXE-like disorder with multiple coagulation factor deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit GGCX

  • gamma-glutamyl carboxylase (GGCX) Antikörper
  • gamma-glutamyl carboxylase (ggcx) Antikörper
  • gamma-glutamyl carboxylase (GC) Antikörper
  • gamma-glutamyl carboxylase (sce5891) Antikörper
  • gamma-glutamyl carboxylase (Ggcx) Antikörper
  • cb751 Antikörper
  • CG13927 Antikörper
  • dgammaC Antikörper
  • dGC Antikörper
  • Dmel\\CG13927 Antikörper
  • gammaC Antikörper
  • GGC Antikörper
  • ggcx Antikörper
  • si:ch1073-230p18.3 Antikörper
  • VKCFD1 Antikörper
  • zgc:158736 Antikörper

Bezeichner auf Proteinebene für GGCX

gamma-glutamyl carboxylase , vitamin K-dependent gamma-carboxylase , peptidyl-glutamate 4-carboxylase , vitamin K gamma glutamyl carboxylase , CG13927-PA , CG13927-PB , GC-PA , GC-PB , gamma-glutamyl-carboxylase , gamma glutamyl carboxylase

GENE ID SPEZIES
459364 Pan troglodytes
557240 Danio rerio
695628 Macaca mulatta
780874 Ciona intestinalis
100144666 Xenopus (Silurana) tropicalis
100171564 Pongo abelii
38194 Drosophila melanogaster
5810488 Sorangium cellulosum So ce56
444473 Xenopus laevis
2677 Homo sapiens
281190 Bos taurus
56316 Mus musculus
81716 Rattus norvegicus
475769 Canis lupus familiaris
443129 Ovis aries
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