Zinc Finger Protein 36, C3H Type, Homolog (Mouse) Proteine (ZFP36)

mRNA-binding protein involved in post-transcriptional regulation of AU-rich element (ARE)-containing mRNAs. Zusätzlich bieten wir Ihnen ZFP36 Antikörper (78) und ZFP36 Kits (9) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Maus ZFP36 ZFP36 67150 Q99MB7
ZFP36 7538 P26651
Ratte ZFP36 ZFP36 79426 P47973
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Showing 3 out of 3 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage

ZFP36 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,

Am meisten referenzierte ZFP36 Proteine

  1. Human ZFP36 Protein expressed in Wheat germ - ABIN1325745 : McDermott, Ellis, Bou-Gharios, Clegg, Tew: RNA binding proteins regulate anabolic and catabolic gene expression in chondrocytes. in Osteoarthritis and cartilage 2016 (PubMed)

Weitere Proteine zu Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36) Interaktionspartnern

Mouse (Murine) Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36) Interaktionspartner

  1. Posttranscriptional gene regulation by TTP schedules the termination of the antimicrobial engagement of neutrophils.

  2. the gain-of-function mutation of TTP impairs IL-10 (zeige IL10 Proteine)-mediated negative feedback control of macrophage function in vitro.

  3. Studies indicate that mice lacking tristetraprolin (TTP) developed a spontaneous and pervasive inflammatory syndrome.

  4. The data demonstrate that cigarette smoke exposure reduces TTP expression and impairs TTP function, resulting in significantly increased TNF-alpha (zeige TNF Proteine) mRNA stability and excessive TNF-alpha (zeige TNF Proteine) expression in alveolar macrophages and epithelial cells.

  5. study uncovers a role of TTP as a suppressor of feedback inhibitors of inflammation and highlights the importance of fine-tuned TTP activity-regulation by MK2 (zeige KCNA2 Proteine) in order to control the pro-inflammatory response

  6. TTP is not involved in LPS (zeige TLR4 Proteine)-mediated destabilization of PLCbeta-2 mRNA in macrophages

  7. Zinc Finger Protein 36 (zeige ZKSCAN1 Proteine) deficiency has profound effects on the splenic transcriptome.

  8. Mouse LARP4 is regul (zeige LARP4 Proteine)ated by TNF-alpha in a TT (zeige TNF Proteine)P-dependent manner.

  9. Regulation of mRNAs by tristetraprolin appears to function as one of several critical post-transcriptional regulatory mechanisms controlling satellite cell homeostasis.

  10. Tristetraprolin limits inflammatory cytokine production in tumor-associated macrophages in an mRNA decay-independent manner.

Human Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36) Interaktionspartner

  1. Because TTP (zeige ADAMTS13 Proteine) also represses IL-1beta (zeige IL1B Proteine) expression, it is a dual inhibitor of the IL-1beta (zeige IL1B Proteine) system, regulating expression of the cytokine and the upstream controller NLRP3 (zeige NLRP3 Proteine)

  2. Data show that the synthetic liver X receptors (LXRs) agonist T0901317 promoted cytokines IL-1beta (zeige IL1B Proteine), IL-6 (zeige IL6 Proteine) and TNFalpha (zeige TNF Proteine) mRNA degradation, destabilized TNFalpha (zeige TNF Proteine) mRNA through its 3'-untranslated region, and increased the expression of tristetraprolin (TTP).

  3. TTP (zeige ADAMTS13 Proteine) was demonstrated to destabilize the VEGF (zeige VEGFA Proteine) mRNA in ARPE-19 cells under hypoxic conditions. Furthermore, CM from TTP (zeige ADAMTS13 Proteine)-overexpressing ARPE-19 cells suppressed tube formation in HUVECs.

  4. this study shows that TTP (zeige ADAMTS13 Proteine) is down-regulated in glioma tissue samples and cell lines, and is associated with diminished survival in glioma patients

  5. TTP (zeige ADAMTS13 Proteine) inhibited the proliferation, migration, and invasion of gastric cancer cell lines through regulation of IL-33 (zeige IL33 Proteine).

  6. Results suggest that ZFP36 proteins might control reepithelialization and angiogenesis in the skin in a multimodal manner.

  7. Our data offer the convincing evidence for the first time that the aberrant expressions of ZFP36 and SOCS3 (zeige SOCS3 Proteine) may be involved into the progression and patients' prognosis of prostate cancer

  8. Low TTP (zeige ADAMTS13 Proteine) expression is associated with epithelial-mesenchymal transition in cancer.

  9. PP2A (zeige PPP2R4 Proteine) activators boost the anti-inflammatory function of TTP (zeige ADAMTS13 Proteine) and have implications for future pharmacotherapeutic strategies to combat inflammation in respiratory disease.

  10. The mRNA destabilizing activity of TTP (zeige ADAMTS13 Proteine) was increased when the partially disordered RNA binding domain (RBD (zeige CACNA1D Proteine)) of TTP (zeige ADAMTS13 Proteine) was replaced with the fully structured RBD (zeige CACNA1D Proteine) of TIS11d (zeige ZFP36L2 Proteine), indicating that differences in the folded state of the RBD (zeige CACNA1D Proteine) affect the activity of the proteins in the cell.

Pig (Porcine) Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36) Interaktionspartner

  1. direct interaction between TTP protein and porcine TNF-alpha (zeige TNF Proteine) mRNA ARE probe

ZFP36 Protein Überblick

Protein Überblick

mRNA-binding protein involved in post-transcriptional regulation of AU-rich element (ARE)-containing mRNAs. Acts by specifically binding ARE-containing mRNAs and promoting their degradation. Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF).

Genbezeichner und Symbole assoziert mit ZFP36

  • tristetraproline (EDI_287240)
  • Tristetraproline (Bm1_42085)
  • tristetraproline (LOAG_03119)
  • similar to Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth (ZFP36)
  • zinc finger protein 36, C3H type, homolog (mouse) (ZFP36)
  • ZFP36 ring finger protein (zfp36)
  • ring finger protein 141 (Rnf141)
  • ZFP36 ring finger protein (ZFP36)
  • zinc finger protein 36 (Zfp36)
  • 2610110L04Rik Protein
  • AA792898 Protein
  • AU022812 Protein
  • c3h-1 Protein
  • G0S24 Protein
  • Gos24 Protein
  • Nup475 Protein
  • RNF162A Protein
  • Tis11 Protein
  • TIS11D Protein
  • TISII Protein
  • Ttp Protein
  • Zfp-36 Protein
  • ZFP36 Protein
  • ZNF230 Protein

Bezeichner auf Proteinebene für ZFP36

tristetraproline , Tristetraproline , similar to Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth , zinc finger protein 36, C3H type, homolog (mouse) , tristetraprolin , zinc finger protein 36, C3H type, homolog , RING finger protein 141 , zinc finger protein 230 , CCCH zinc finger protein C3H-1 , G0/G1 switch regulatory protein 24 , growth factor-inducible nuclear protein NUP475 , zinc finger protein 36 homolog , zinc finger protein, C3H type, 36 homolog , TTP , zfp-36 , TPA-induced sequence 11 , CCCH (CX8CX5CX3H) zinc finger domain RNA-binding protein , TIS11 , zinc finger protein homologous to Zfp-36 in mouse , TNF alpha inhibitor , Tax interacting protein

5879635 Entamoeba dispar SAW760
6103302 Brugia malayi
9940506 Loa loa
698280 Macaca mulatta
736203 Pan troglodytes
100127733 Xenopus (Silurana) tropicalis
67150 Mus musculus
398102 Xenopus laevis
7538 Homo sapiens
79426 Rattus norvegicus
22695 Mus musculus
484510 Canis lupus familiaris
100316849 Sus scrofa
282127 Bos taurus
443283 Ovis aries
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