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SH3GL1 encodes a member of the endophilin family of Src homology 3 domain-containing proteins. Zusätzlich bieten wir Ihnen SH3GL1 Kits (10) und SH3GL1 Proteine (9) und viele weitere Produktgruppen zu diesem Protein an.
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Mammalian Monoclonal SH3GL1 Primary Antibody für ISt, IHC - ABIN1304949
Micheva, Smith: Array tomography: a new tool for imaging the molecular architecture and ultrastructure of neural circuits. in Neuron 2007
Show all 3 Pubmed References
Endophilin-A2 was identified as a novel molecule regulating macrophage-derived foam cell formation by mechanisms attributable to clathrin-mediated endocytosis and beyond clathrin-mediated endocytosis
inhibition of SH3GL1 reverses multidrug resistance through declining P-glycoprotein expression via the EGFR (zeige EGFR Antikörper)/ERK (zeige EPHB2 Antikörper)/AP-1 (zeige FOSB Antikörper) pathway.
results establish a novel function of endoA2 in clathrin-independent endocytosis
these data suggest that EEN may play a pivotal role in excessive cell proliferation and insufficient cell apoptosis of bone marrow plasma cells in multiple myeloma.
MIR218 functions as a tumor suppressor by regulating SH3GL1 expression in medulloblastoma cancer cells.
SH3GL1 may be involved in the oncogenic process of gliomas and effectively elicit an autologous antibody response in low-grade gliomas.
Two endophilin A2 mutants, E264A and E264R, have different effects on how endophilin interacts with other proteins, such as dynamin (zeige DNM1 Antikörper) or beta1-adrenergic receptors.
Idiopathic scoliosis is a multifactorial genetic disease and SH3GL1 may be one of the pathogenic genes for this disease.
SH3GL1 is possibly one of the disease associated genes of adolescent idiopathic scoliosis.
new mechanism for MLL (zeige MLL Antikörper)-EEN-mediated leukemogenesis in which MLL (zeige MLL Antikörper)-EEN interferes with the Ras-suppressing activities of EBP (zeige EBP Antikörper) through direct interaction.
This study provides a new mechanism by which endophilin A2 regulates ClC-3 (zeige CLCN3 Antikörper) channel activity, and sheds light on how ClC-3 (zeige CLCN3 Antikörper) is transported to cell membranes to play its critical role as a chloride channel (zeige CLCA1 Antikörper) in VSMCs function
Mutation in the FAK (zeige PTK2 Antikörper) gene disrupted the function of FAK (zeige PTK2 Antikörper) scaffolding to mediate endophilin A2 phosphorylation at Tyr (zeige TYR Antikörper)-315 by Src (zeige SRC Antikörper), leading to the decreased surface expression of MT1-MMP (zeige MMP14 Antikörper).
these results demonstrate that MNSFbeta (zeige FAU Antikörper)/endophilin II inhibits the signal pathway upstream of IKK (zeige CHUK Antikörper) activation, but not downstream of TLR2 (zeige TLR2 Antikörper) signaling.
Further analysis based on antibody staining of central and peripheral nerves revealed beta-adducin (zeige ADD2 Antikörper), septin 2 (zeige SEPT2 Antikörper), and sh3p8 as putative paranodal proteins.
Mll (zeige MLL Antikörper)(Een/+) chimeric mice developed leukaemia displaying enlarged livers, spleens, thymuses and lymph nodes owing to infiltration of Mll (zeige MLL Antikörper)(Een/+)-expressing leukemic cells
post-translational modification of endophilin II by MNSFbeta (zeige FAU Antikörper) might be implicated in phagocytosis by macrophages.
This gene encodes a member of the endophilin family of Src homology 3 domain-containing proteins. The encoded protein is involved in endocytosis and may also play a role in the cell cycle. Overexpression of this gene may play a role in leukemogenesis, and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the myeloid-lymphoid leukemia protein. Pseudogenes of this gene are located on the long arm of chromosomes 11 and 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
SH3-domain GRB2-like 1
, EEN fusion partner of MLL
, SH3 domain protein 2B
, SH3 domain-containing GRB2-like protein 1
, SH3-containing Grb-2-like 1 protein
, extra 11-19 leukemia fusion
, extra eleven-nineteen leukemia fusion gene protein
, endophilin II
, SH3 domain-containing GRB2-like protein 2