anti-Ring Finger Protein 2 (RNF2) Antikörper

Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. Zusätzlich bieten wir Ihnen RNF2 Proteine (7) und RNF2 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
RNF2 6045 Q99496
RNF2 19821 Q9CQJ4
RNF2 304850 Q4KLY4
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Top anti-RNF2 Antikörper auf

Showing 10 out of 64 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-RNF2 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Daudi cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-RNF2 Antibody Titration: </b>1.25ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
288,68 €
Human Maus Unkonjugiert WB Western Blot analysis of RNF2 expression in transfected 293T cell line by RNF2 monoclonal antibody (M01), clone 6C2. Lane 1: RNF2 transfected lysate(37.7 KDa). Lane 2: Non-transfected lysate. Western blot analysis of RNF2 over-expressed 293 cell line, cotransfected with RNF2 Validated Chimera RNAi used as specificity and loading control. 0.1 mg Anmelden zum Anzeigen 12 bis 16 Tage
454,76 €
Hamster Maus Unkonjugiert IP, WB 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
484,00 €
Human Ziege Unkonjugiert ELISA, WB ABIN184925 staining (0.5 µg/ml) of K562 lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Anmelden zum Anzeigen 3 bis 4 Tage
349,82 €
Human Maus Unkonjugiert WB RNF2 monoclonal antibody (M14), clone 2B4. Western Blot analysis of RNF2 expression in A-549. 0.1 mg Anmelden zum Anzeigen 12 bis 16 Tage
454,76 €
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of RING2/RING1B/RNF2 expression in rat brain extract (lane 1), and HELA whole cell lysates (lane 2). RING2/RING1B/RNF2 at 38KD was detected using rabbit anti- RING2/RING1B/RNF2 Antigen Affinity purified polyclonal antibody at0.5 μg/mL. The blot was developed using chemiluminescence (ECL) method RING2/RING1B/RNF2 was detected in paraffin-embedded sections of human mammary cancer tissues using rabbit anti- RING2/RING1B/RNF2 Antigen Affinity purified polyclonal antibody at 1 μg/mL. The immunohistochemical section was developed using SABC method 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
298,57 €
Huhn Ziege Unkonjugiert EIA, IF, IHC (p), WB   0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
495,00 €
Human Kaninchen Unkonjugiert IHC, IHC (p), IP, WB Western Blot: RNF2 Antibody [NBP1-49966] - Detection of Human and Mouse RNF2 by Western Blot (h&m) and Immunoprecipitation (h). Samples: Whole cell lysate from K562 (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded), 293T (T; 50 mcg), and mouse NIH3T3 (M; 50 mcg) cells. Antibodies: Affinity purified rabbit anti-RNF2 antibody used for WB at 0.1 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate. RNF2 was also immunoprecipitated by rabbit anti-RNF2 antibody, which recognizes a downstream epitope. For blotting immunoprecipitated RNF2 was used. Detection: Chemiluminescence with exposure times of 30 seconds (A and B). Immunohistochemistry-Paraffin: RNF2 Antibody [NBP1-49966] - Human prostate carcinoma. Antibody used at a dilution of 1:1,000. 100 μL Anmelden zum Anzeigen 2 bis 4 Tage
371,00 €
Human Maus Unkonjugiert ChIPSeq, ChIP, ICC, IF, IP, WB Ring1B antibody (mAb) tested by ChIP-chip. ChIP was performed using the ChIP-IT® High Sensitivity Kit (Cat. No. 53040) with chromatin from 4.5 million human embryonic stem cells and 4 µl of antibody. ChIP DNA was amplified by WGA, labeled and hybridized to a human tiling array. The two images show regions of strong binding on chromosomes 2 and 9. 100 μg Anmelden zum Anzeigen 1 bis 3 Tage
508,33 €

RNF2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human ,
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Mouse (Murine)
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Rat (Rattus)

Am meisten referenzierte anti-RNF2 Antikörper

  1. Human Monoclonal RNF2 Primary Antibody für ChIPSeq, ChIP - ABIN2668629 : Basu, Wilkinson, Colavita, Fennelly, Atchison: YY1 DNA binding and interaction with YAF2 is essential for Polycomb recruitment. in Nucleic acids research 2014 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal RNF2 Primary Antibody für RNAi, ELISA - ABIN562662 : Ohtsubo, Yasunaga, Ohno, Tsumura, Okada, Ishikawa, Shirao, Kikuchi, Nishitani, Kobayashi, Takihara: Polycomb-group complex 1 acts as an E3 ubiquitin ligase for Geminin to sustain hematopoietic stem cell activity. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal RNF2 Primary Antibody für IHC, IHC (p) - ABIN4350772 : Holdt, Hoffmann, Sass, Langenberger, Scholz, Krohn, Finstermeier, Stahringer, Wilfert, Beutner, Gielen, Schuler, Gäbel, Bergert, Bechmann, Stadler, Thiery, Teupser: Alu elements in ANRIL non-coding RNA at chromosome 9p21 modulate atherogenic cell functions through trans-regulation of gene networks. in PLoS genetics 2013 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal RNF2 Primary Antibody für ELISA, WB - ABIN268569 : Tuckfield, Clouston, Wilanowski, Zhao, Cunningham, Jane: Binding of the RING polycomb proteins to specific target genes in complex with the grainyhead-like family of developmental transcription factors. in Molecular and cellular biology 2002 (PubMed)

Weitere Antikörper gegen RNF2 Interaktionspartner

Zebrafish Ring Finger Protein 2 (RNF2) Interaktionspartner

  1. The polycomb group protein (zeige CBX4 Antikörper) ring1b/rnf2 is specifically required for craniofacial development.

  2. These results reveal that, in the absence of functional Ring1b, fin bud cells fail to execute the pectoral fin developmental program.

Human Ring Finger Protein 2 (RNF2) Interaktionspartner

  1. Study detected RNF2 expression to be overexpressed in esophageal carcinoma cell lines and was associated with the poor prognosis of esophageal carcinoma patients. Data also reflect its important role in the growth of esophageal carcinoma cells by shRNA silencing of RNF2 expression.

  2. overexpression of RNF2, as examined by immunohistochemical analysis, might serve as a novel prognostic biomarker and potential therapeutic target for urothelial carcinoma of the bladder patients.

  3. Our findings support the notion that epigenetic regulators, such as RNF2, directly and functionally control powerful gene networks that are vital in multiple cancer processes.

  4. O-GlcNAc (zeige OGT Antikörper) modifies and regulates an essential epigenetic tool, RING1B, which may contribute to human embryonic stem cells pluripotency maintenance and differentiation.

  5. The enzymatic activity of BMI1 (zeige BMI1 Antikörper) and RING1B were evaluated and compared.

  6. Bmi1 (zeige BMI1 Antikörper) and possibly RNF2 may be attractive biomarkers of gemcitabine resistance in the context of RRM1 (zeige RRM1 Antikörper) expression.

  7. combinatorial silencing along with Ezh2 (zeige EZH2 Antikörper) depleted epigenetically modified H2- and H3-histones and inhibited pancreatic cancer cell growth in vitro and in vivo (xenograft model)

  8. BAP1 deficiency causes increased expression of FoxK2 (zeige FOXK2 Antikörper) target genes in a Ring1B-Bmi1 (zeige BMI1 Antikörper)-dependent manner

  9. Authors describe a critical role for the polycomb group protein Ring1b in nonhomologous end-joining (NHEJ)-mediated end-to-end chromosome fusions.

  10. we identify p63 (zeige RPE65 Antikörper) as a target of Ring1B to regulate Fak (zeige PTK2 Antikörper) expression in breast cancer epithelial cells

Mouse (Murine) Ring Finger Protein 2 (RNF2) Interaktionspartner

  1. the ability of RING1B, a core component of PRC1 (zeige PRC1 Antikörper), to ubiquitinate histone H2A is dispensable for early mouse embryonic development and much of the gene repression activity of PRC1 (zeige PRC1 Antikörper)

  2. RNF2 associates with AMBRA1 (zeige AMBRA1 Antikörper) to act as an E3 ligase to ubiquitinate AMBRA1 (zeige AMBRA1 Antikörper) via K48 linkage.

  3. The polycomb (zeige CBX2 Antikörper) component Ring1B regulates the timed termination of Fezf2 (zeige FEZF2 Antikörper) expression and thus subcerebral projection neuron production during mouse neocortical development.

  4. Expansion of hepatic stem/progenitor cells requires Ring1B-mediated epigenetic silencing of Cdkn1a (zeige CDKN1A Antikörper) and Cdkn2a (zeige CDKN2A Antikörper), demonstrating that Ring1B simultaneously regulates multiple CDKIs in tissue stem/progenitor cells.

  5. Af9 (zeige MLLT3 Antikörper) mediates site-selective physical and functional recruitment of Rnf2 to the alpha-ENaC (zeige SCNN1A Antikörper) promoter to constrain basal alpha-ENaC (zeige SCNN1A Antikörper) transcription in collecting duct cells.

  6. Ring1b mediates Meis2 (zeige MEIS2 Antikörper) promoter and midbrain-specific enhancer association.

  7. Aurora B (zeige AURKC Antikörper) and Ring1B co-occupy active promoters in resting lymphocytes.

  8. Fbxl10 (zeige KDM2B Antikörper) has a key role in regulating Ring1B recruitment to its target genes and H2AK119 ubiquitylation in embryonic stem cells.

  9. identification of gene-dosage-dependent roles in primordial germ cell development for Ring1 (zeige RING1 Antikörper) and Rnf2, two central components of the Polycomb (zeige CBX2 Antikörper) repressive complex 1 (PRC1 (zeige PRC1 Antikörper))

  10. Ring1b inactivation in differentiated islet beta cells (Ring1b(betaKO)) did not cause derepression, even after multiple rounds of cell division, suggesting a role for Ring1b in the establishment but not the maintenance of repression

RNF2 Antigen-Profil

Protein Überblick

Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.

Genbezeichner und Symbole assoziert mit RNF2

  • ring finger protein 2 (rnf2) Antikörper
  • ring finger protein 2 (RNF2) Antikörper
  • ring finger protein 2 (Rnf2) Antikörper
  • AI326319 Antikörper
  • AI450156 Antikörper
  • AU019207 Antikörper
  • bap-1 Antikörper
  • bap1 Antikörper
  • ding Antikörper
  • fa19h05 Antikörper
  • hipi3 Antikörper
  • Ring1B Antikörper
  • ring2 Antikörper
  • wu:fa19h05 Antikörper
  • wz4556 Antikörper

Bezeichner auf Proteinebene für RNF2

E3 ubiquitin-protein ligase RING2 , ring finger protein 1b , wz4566 , RING finger protein 1B , HIP2-interacting protein 3 , RING finger protein BAP-1 , huntingtin-interacting protein 2-interacting protein 3 , protein DinG , RING1b

327035 Danio rerio
424452 Gallus gallus
457581 Pan troglodytes
100174504 Pongo abelii
6045 Homo sapiens
480042 Canis lupus familiaris
540090 Bos taurus
19821 Mus musculus
304850 Rattus norvegicus
100127274 Xenopus laevis
Ausgewählte Anbieter für anti-RNF2 (RNF2) Antikörper
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