anti-Neutrophil Cytosolic Factor 2 (NCF2) Antikörper

NCF2 encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. Zusätzlich bieten wir Ihnen NCF2 Proteine (12) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
NCF2 4688 P19878
NCF2 17970 O70145
NCF2 364018 A7E3N2
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Top anti-NCF2 Antikörper auf

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Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Maus Unkonjugiert IF, WB Western blot analysis of p67 [phox] on a EB1 cell lysate (Human B lymphoblast, Burkitt's lymphoma, ATCC HTB-60). Lane 1: 1:500, lane 2: 1:1000, lane 3: 1:2000 dilution of the mouse anti-p67 [phox] antibody. Immunofluorescence staining of C3H/10T1/2 cells (Mouse embryonic fibroblasts, ATCC CCL-226). 50 μg Anmelden zum Anzeigen 2 bis 4 Tage
146,73 €
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-NCF2 Antibody Titration: 1.0 ug/ml Positive Control: MCF7 Whole Cell 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunofluorescence: p67phox/NOXA2 Antibody [NBP1-82542] - Immunofluorescent staining of human cell line A-431 shows positivity in cytoplasm. Western Blot: p67phox/NOXA2 Antibody [NBP1-82542] - Lane 1: Marker [kDa] 229, 112, 84, 48, 32, 27, 17.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp.Lane 4: Human plasma (IgG/HSA depleted) 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Human Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
Human Kaninchen Unkonjugiert IHC (p), WB Human Spleen, Neutrophils (formalin-fixed, paraffin-embedded) stained with NCF2 antibody ABIN305776 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
801,43 €
Human Kaninchen Unkonjugiert ICC, IF, IHC, IP, WB Immunohistochemistry of paraffin-embedded mouse heart using NCF2 antibody at dilution of 1:100 (400x lens). 100 μL Anmelden zum Anzeigen 12 Days
261,90 €
Human Kaninchen Unkonjugiert ICC, IHC, IP, WB 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
299,05 €
Maus Kaninchen Unkonjugiert IHC, WB Immunofluorescence analysis of HeLa cell using NCF2 antibody. Blue: DAPI for nuclear staining. 100 μL Anmelden zum Anzeigen 11 bis 13 Tage
282,86 €
Maus Kaninchen Unkonjugiert ICC, IHC, IP, WB 100 μg Anmelden zum Anzeigen 11 bis 15 Tage
308,57 €
Human Kaninchen Unkonjugiert IC, IF, IP, IHC, WB Immunofluorescent analysis of p67 phox staining in Hela cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibo Immunohistochemical analysis of p67 phox staining in mouse heart formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with th 200 μL Anmelden zum Anzeigen 11 bis 13 Tage
464,29 €

NCF2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-NCF2 Antikörper

  1. Human Monoclonal NCF2 Primary Antibody für IF, WB - ABIN968245 : Ago, Nunoi, Ito, Sumimoto: Mechanism for phosphorylation-induced activation of the phagocyte NADPH oxidase protein p47(phox). Triple replacement of serines 303, 304, and 328 with aspartates disrupts the SH3 domain-mediated intramolecular interaction in p47(phox), thereby activating in The Journal of biological chemistry 1999 (PubMed)
    Zeige alle 5 Referenzen für 968245

  2. Human Polyclonal NCF2 Primary Antibody für ICC, IF - ABIN4343179 : Lomnytska, Becker, Bodin, Olsson, Hellman, Hellström, Mints, Hellman, Auer, Andersson: Differential expression of ANXA6, HSP27, PRDX2, NCF2, and TPM4 during uterine cervix carcinogenesis: diagnostic and prognostic value. in British journal of cancer 2011 (PubMed)

Weitere Antikörper gegen NCF2 Interaktionspartner

Pig (Porcine) Neutrophil Cytosolic Factor 2 (NCF2) Interaktionspartner

  1. analysis of NCF2, BCKDHB (zeige BCKDHB Antikörper) and BCKDHA (zeige BCKDHA Antikörper) in pig

Human Neutrophil Cytosolic Factor 2 (NCF2) Interaktionspartner

  1. Phosphoinositol 3-phosphate regulates reactive oxygen species production by maintaining p40phox (zeige NCF4 Antikörper) and p67phox at the phagosomal membrane.

  2. TLR4 (zeige TLR4 Antikörper)- and TLR2 (zeige TLR2 Antikörper)-induced IRAK (zeige IRAK1 Antikörper)-ERK (zeige EPHB2 Antikörper) pathway cross-talks with p67phox-Nox-2 (zeige CYBB Antikörper) for reactive oxygen species generation, thus regulating IL-1beta (zeige IL1B Antikörper) transcription and processing in monocytic cells.

  3. Skeletal muscle protein expression of the NADPH oxidase (zeige NOX1 Antikörper) subunits p22(phox (zeige CYBA Antikörper)), p47(phox), and p67(phox) was increased in obese relative to lean subjects, where p22(phox (zeige CYBA Antikörper)) and p67(phox) expression was attenuated by exercise training in obese subjects.

  4. A novel homozygous mutation in NCF2.

  5. results reveal an essential role for the Cys (zeige DNAJC5 Antikörper)-Gly-Cys (zeige DNAJC5 Antikörper) triad in Nox2 (zeige CYBB Antikörper) in binding p67(phox), seconded by an additional binding region, comprising residues C terminal to Cys (zeige DNAJC5 Antikörper)-Gly-Cys (zeige DNAJC5 Antikörper). The 2 regions interact with distinct partner sites in p67(phox).

  6. This model assigns a central role to Arg-395 in the structure and stability of the quaternary NCF2/NCF4 (zeige NCF4 Antikörper)/VAV1 (zeige VAV1 Antikörper)/RAC1 NADPH oxidase (zeige NOX1 Antikörper) complex.

  7. Data indicate that arachidonic acid induces the direct interaction of Rac (zeige AKT1 Antikörper)-GTP (zeige AK3 Antikörper)-bound p67(phox) with the C-terminal cytosolic region of phagocyte NADPH oxidase (zeige NOX1 Antikörper) Nox2 (zeige CYBB Antikörper).

  8. Four novel mutations in the NCF1 (zeige NCF1 Antikörper), NCF2, and CYBB (zeige CYBB Antikörper) genees have been identified in chronic granulomatous disease patients in Morocco.

  9. Results not only establish allelic heterogeneity within NCF2 associated with SLE, but also emphasize the utility of multi-ethnic cohorts to identify predisposing variants explaining additional phenotypic variance of complex diseases like SLE.

  10. NCF2 in Asian populations shows a pattern of diversity characterized by a differentiated haplotype structure.

Mouse (Murine) Neutrophil Cytosolic Factor 2 (NCF2) Interaktionspartner

  1. Just as patients with chronic granulomatous disease who lack NADPH oxidase (zeige NOX1 Antikörper) rarely develop SLE, NCF-2-null mice on a nonautoimmune background were susceptible to a chronic granulomatous disease-like opportunistic infection but did not develop lupus. In contrast, on a lupus-prone background, even haploinsufficiency of NCF-2 accelerated the development of full-blown lupus disease.

  2. p67(phox) binds to phosphoPrdx6 and inhibits its PLA2 (zeige PLA2G2A Antikörper) activity, an interaction that could function to terminate the PLA2 (zeige PLA2G2A Antikörper)-mediated NOX2 (zeige CYBB Antikörper) activation signal.

  3. The results of this study suggested that repeated stress promotes depressive behavior through the upregulation of NADPH (zeige FDXR Antikörper) oxidasesubunit (67kDa (zeige RPSA Antikörper)) and the resultant metabolic oxidative stress.

  4. Data suggest that a cytosolic source of reactive oxygen species, probably p67(phox) subunit of cardiac NADPH oxidase 2 (NOX2 (zeige CYBB Antikörper)), may contribute to the hypertrophic phenotype in glucose transporter 4 gene (GLUT4 (zeige SLC2A4 Antikörper)-/-) mice.

  5. This report evaluates neutrophil cytosolic factor 2 (Ncf2) as a candidate Salmonella susceptibility gene for Ity3.

  6. This study demonstrates the involvement of ROS (zeige ROS1 Antikörper) from NADPH oxidase (zeige NOX1 Antikörper) in mediating paraquat cytotoxicity in BV-2 microglial cells and this process is mediated through PKCdelta (zeige PKCd Antikörper)- and ERK (zeige EPHB2 Antikörper)-dependent pathways.

NCF2 Antigen-Profil

Protein Überblick

This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms.

Genbezeichner und Symbole assoziert mit NCF2

  • neutrophil cytosolic factor 2 (NCF2) Antikörper
  • neutrophil cytosolic factor 2 (ncf2) Antikörper
  • neutrophil cytosolic factor 2 (p67phox) Antikörper
  • neutrophil cytosol factor 2 (VDBG_06643) Antikörper
  • neutrophil cytosolic factor 2 (PGTG_05816) Antikörper
  • neutrophil cytosolic factor 2 (LOC100136240) Antikörper
  • neutrophil cytosolic factor 2 (Ncf2) Antikörper
  • MGC81877 Antikörper
  • Ncf-2 Antikörper
  • NOXA2 Antikörper
  • P67-PHOX Antikörper
  • P67PHOX Antikörper
  • zgc:158405 Antikörper

Bezeichner auf Proteinebene für NCF2

neutrophil cytosolic factor 2 (65kDa, chronic granulomatous disease, autosomal 2) , neutrophil cytosolic factor 2 , neutrophil cytosol factor 2 , predicted neutrophil cytosolic factor 2 , p67phox , p67-phox , NADPH oxidase cytosolic protein p67phox , NADPH oxidase cytosolic protein , 67 kDa neutrophil oxidase factor , NADPH oxidase activator 2 , chronic granulomatous disease, autosomal 2 , neutrophil NADPH oxidase factor 2 , neutrophil cytosolic factor 2 (65kD, chronic granulomatous disease, autosomal 2) , NADPH oxidase subunit (67 kD) , NADPH oxidase subunit (67kDa) , NCF-2

424445 Gallus gallus
444487 Xenopus laevis
457573 Pan troglodytes
480036 Canis lupus familiaris
562473 Danio rerio
619224 Ciona intestinalis
619367 Xenopus (Silurana) tropicalis
9537124 Verticillium alfalfae VaMs.102
10531323 Puccinia graminis f. sp. tritici CRL 75-36-700-3
100008802 Oryctolagus cuniculus
100136240 Oncorhynchus mykiss
100142665 Sus scrofa
100174692 Pongo abelii
100270811 Salmo salar
4688 Homo sapiens
17970 Mus musculus
364018 Rattus norvegicus
281346 Bos taurus
Ausgewählte Anbieter für anti-NCF2 (NCF2) Antikörper
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