Doublecortin-Like Kinase 1 (DCLK1) ELISA Kits

DCLK1 encodes a member of the protein kinase superfamily and the doublecortin family. Zusätzlich bieten wir Ihnen DCLK1 Antikörper (116) und DCLK1 Proteine (17) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
DCLK1 9201 O15075
DCLK1 13175 Q9JLM8
DCLK1 83825 O08875
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Top DCLK1 ELISA Kits auf

Showing 8 out of 24 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Maus 0.059 ng/mL 0.15-10 ng/mL 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
Human 0.053 ng/mL 0.156-10 ng/mL 96 Tests Anmelden zum Anzeigen 15 bis 17 Tage
Meerschweinchen 0.094 ng/mL 0.156-10 ng/mL   96 Tests Anmelden zum Anzeigen 12 bis 14 Tage
Schwein 0.094 ng/mL 0.156-10 ng/mL   96 Tests Anmelden zum Anzeigen 12 bis 14 Tage
Kaninchen 37.5 pg/mL 62.5-4000 pg/mL   96 Tests Anmelden zum Anzeigen 12 bis 14 Tage
Huhn 0.094 ng/mL 0.156-10 ng/mL   96 Tests Anmelden zum Anzeigen 12 bis 14 Tage
Affe 0.094 ng/mL 0.156-10 ng/mL   96 Tests Anmelden zum Anzeigen 12 bis 14 Tage
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage

Am meisten referenzierte DCLK1 ELISA Kits

  1. Mouse (Murine) DCLK1 ELISA Kit für Sandwich ELISA - ABIN428382 : Qu, Johnson, Chandrakesan, Weygant, May, Aiello, Rhim, Zhao, Zheng, Lightfoot, Pant, Irvan, Postier, Hocker, Hanas, Ali, Sureban, An, Schlosser, Stanger, Houchen: Doublecortin-like kinase 1 is elevated serologically in pancreatic ductal adenocarcinoma and widely expressed on circulating tumor cells. in PLoS ONE 2015 (PubMed)

Weitere ELISA Kits für DCLK1 Interaktionspartner

Zebrafish Doublecortin-Like Kinase 1 (DCLK1) Interaktionspartner

  1. These results suggest that both the kinase domain and the Ser (zeige SIGLEC1 ELISA Kits)/Pro-rich domain are involved in regulating the microtubule-binding activity of doublecortin (zeige DCX ELISA Kits)-like protein kinase (zeige TGFB3 ELISA Kits) (DCLK (zeige DCLK2 ELISA Kits)).

  2. DCLK (zeige DCLK2 ELISA Kits) mediates its neuronal functions through phosphorylation of physiological substrates such as synapsin II (zeige SYN2 ELISA Kits)

  3. Gene knockdown studies of zDCLK (zeige DCLK2 ELISA Kits) suggest that zDCLK (zeige DCLK2 ELISA Kits) may play crucial roles in the central nervous systems during the early stage of embryogenesis.

Human Doublecortin-Like Kinase 1 (DCLK1) Interaktionspartner

  1. Generated a (doublecortin like kinase 1) DCLK1-S-specific polyclonal antibody (S-isoform specific), and studied its use in screening of colon cancer after colonoscopy.

  2. DCLK1 expression was observed in tumor cells in patients with pathological stage I non-small cell lung cancer (NSCLC)and was correlated with adverse prognosis, especially in patients with adenocarcinoma. DCLK1 may be a potential new therapeutic target

  3. Biochemical and structural characterization of DCLK1 allowed for the mapping of cancer-causing mutations within the kinase domain.

  4. Our results indicate that Dclk1 is essential in advancing intestinal tumorigenesis. Knocking down Dclk1 decreases tumor stemness and progression and is thus predicted to regulate pro-survival signaling and tumor cell pluripotency.

  5. The univariate and multivariate analyses suggested DCAMKL1 protein overexpression was an unfavorable prognostic factor in bladder cancer patients. In conclusion, DCAMKL1 is an independent poor prognostic factor for bladder cancer patients.

  6. DCLK1 induction and its overexpression following hepatic injury are likely to contribute to tumorigenesis including maintenance and dissemination of tumor cells in circulation.

  7. first evidence for the suppressive activity of miR (zeige MLXIP ELISA Kits)-613 in hepatocellular carcinoma, which is causally linked to targeting of DCLK1

  8. MSX1 (zeige MSX1 ELISA Kits) and DCLK1 might be used in colorectal cancer detection or as target of cancer therapies.

  9. Increased expression of stromal DCLK1 was detected in endometriotic tissue compared to endometriosis patient endometrium. Stromal expression of DCLK1 was increased in endometrium of endometriosis patients compared to controls.

  10. DCLK1 up-regulation may play a contributory role in colorectal cancer metastasis and poor prognosis via activation of EMT (zeige ITK ELISA Kits). DCLK1 may serve as an independent predictor for CRC (zeige CALR ELISA Kits) prognosis.

Mouse (Murine) Doublecortin-Like Kinase 1 (DCLK1) Interaktionspartner

  1. Dclk1 contributes functionally to the pathogenesis of pancreatic cancer; Dclk1 marks quiescent pancreatic progenitors that are candidates for the origin of pancreatic cancer

  2. loss of parietal cells leads to the reversible emergence of a novel Dclk1-expressing sensory cell population in the gastric mucosa.

  3. Dclk1 plays an important role in regulating colonic inflammatory response and colonic epithelial integrity

  4. Dclk1 promotes axonal regeneration, neuronal survival, and growth core reformation via microtubule stabilization, prevention of F-actin destabilization and synergy with mTOR (zeige FRAP1 ELISA Kits).

  5. Dclk1 is critically involved in facilitating intestinal tumorigenesis by enhancing pluripotency and EMT (zeige ITK ELISA Kits) factors in Apc (zeige APC ELISA Kits) mutant intestinal tumors and it also provides a potential therapeutic target for the treatment of colorectal cancer.

  6. Dclk1 plays a functional role critical in the epithelial restorative response.

  7. DCLK1 regulates pluripotency and angiogenic factors via microRNA-dependent mechanisms in pancreatic cancer.

  8. These results suggest that crypt epithelial cell Dclk1 expression can be used as one potential marker to evaluate the early survival of intestinal stem cells following severe radiation injury.

  9. Pancreatic neoplasms in mice contain morphologically and functionally distinct subpopulations, expressing DCLK1, that have cancer stem cell-like properties.

  10. DCAMKL1 represses osteoblast activation by antagonizing Runx2 (zeige RUNX2 ELISA Kits), the master transcription factor in osteoblasts.

DCLK1 Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. The encoded protein is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis. This gene is up-regulated by brain-derived neurotrophic factor and associated with memory and general cognitive abilities. Multiple transcript variants generated by two alternative promoter usage and alternative splicing have been reported, but the full-length nature and biological validity of some variants have not been defined. These variants encode different isoforms, which are differentially expressed and have different kinase activities.

Genbezeichner und Symbole assoziert mit DCLK1

  • doublecortin-like kinase 1 (DCLK1) Antikörper
  • doublecortin-like kinase 1a (dclk1a) Antikörper
  • doublecortin-like kinase 2 (dclk2) Antikörper
  • doublecortin-like kinase 1 (Dclk1) Antikörper
  • 1700113D08Rik Antikörper
  • 2810480F11Rik Antikörper
  • AI836758 Antikörper
  • Ania4 Antikörper
  • CL1 Antikörper
  • Click-I Antikörper
  • CLICK1 Antikörper
  • Cpg16 Antikörper
  • Dcamkl1 Antikörper
  • DCDC3A Antikörper
  • Dcl Antikörper
  • Dclk Antikörper
  • dclk1 Antikörper
  • MGC145348 Antikörper
  • mKIAA0369 Antikörper
  • wu:fc51f11 Antikörper
  • zgc:153709 Antikörper

Bezeichner auf Proteinebene für DCLK1

doublecortin-like kinase 1 , doublecortin and CaM kinase-like 1 , doublecortin and calcium/calmodulin-dependent protein kinase-like 1 , serine/threonine-protein kinase DCLK1 , doublecortin-like kinase 2 , serine/threonine-protein kinase DCLK1-like , doublecortin domain-containing protein 3A , doublecortin-like and CAM kinase-like 1 , CLICK-I beta , double cortin and calcium/calmodulin-dependent protein kinase-like 1

467259 Pan troglodytes
477304 Canis lupus familiaris
558997 Danio rerio
587664 Strongylocentrotus purpuratus
613449 Bos taurus
733926 Xenopus (Silurana) tropicalis
100401876 Callithrix jacchus
100484701 Ailuropoda melanoleuca
100062396 Equus caballus
100080521 Ornithorhynchus anatinus
100443787 Pongo abelii
100539645 Meleagris gallopavo
100607261 Nomascus leucogenys
9201 Homo sapiens
13175 Mus musculus
83825 Rattus norvegicus
100521679 Sus scrofa
418903 Gallus gallus
100725335 Cavia porcellus
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