anti-Collagen, Type VIII, alpha 2 (COL8a2) Antikörper

COL8a2 encodes the alpha 2 chain of type VIII collagen. Zusätzlich bieten wir Ihnen COL8a2 Proteine (9) und COL8a2 Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
COL8a2 1296 P25067
COL8a2 329941 P25318
COL8a2 313592  
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Top anti-COL8a2 Antikörper auf antikoerper-online.de

Showing 10 out of 48 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-COL8A2 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: A549 cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
Details
Human Kaninchen Unkonjugiert IF, IHC (p), WB COL8A2 Antibody (C-term) (ABIN655804) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert EIA, IF, IHC (p), WB   0.4 mL Anmelden zum Anzeigen 8 bis 11 Tage
357,50 €
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Rind (Kuh) Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
Details
Human Maus Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 11 bis 14 Tage
635,55 €
Details
Human Kaninchen Unkonjugiert ELISA, IF, IHC, WB   200 μL Anmelden zum Anzeigen 11 bis 14 Tage
941,11 €
Details
Human Kaninchen Unkonjugiert ICC, IHC, IP, WB 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
333,33 €
Details
Human Kaninchen Unkonjugiert WB Western Blot: COL8A2 Antibody [NBP1-79786] - A549 cell lysate, concentration 0.2-1 ug/ml. 100 μL Anmelden zum Anzeigen 3 bis 6 Tage
341,00 €
Details

COL8a2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-COL8a2 Antikörper

  1. Human Polyclonal COL8a2 Primary Antibody für IF, IHC (p) - ABIN655804 : Okumura, Minamiyama, Ho, Kay, Kawasaki, Tourtas, Schlötzer-Schrehardt, Kruse, Young, Quantock, Kinoshita, Koizumi: Involvement of ZEB1 and Snail1 in excessive production of extracellular matrix in Fuchs endothelial corneal dystrophy. in Laboratory investigation; a journal of technical methods and pathology 2015 (PubMed)

  2. Human Polyclonal COL8a2 Primary Antibody für WB - ABIN611143 : De Zeeuw, Hoogenraad, Goedknegt, Hertzberg, Neubauer, Grosveld, Galjart: CLIP-115, a novel brain-specific cytoplasmic linker protein, mediates the localization of dendritic lamellar bodies. in Neuron 1998 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen COL8a2 Interaktionspartner

Human Collagen, Type VIII, alpha 2 (COL8a2) Interaktionspartner

  1. Analysis of SLC4A11 (zeige SLC4A11 Antikörper), ZEB1 (zeige ZEB1 Antikörper), LOXHD1, COL8A2 and TCF4 (zeige TCF4 Antikörper) gene sequences in a multi-generational family with late-onset Fuchs corneal dystrophy found no evidence for found polymorophisms causing the disease in this specific pedigree.

  2. Peripheral, anterior microcystic corneal edema represents a characteristic aspect of the phenotype associated with the p.(Leu450Trp) substitution in COL8A2, in at least 2 of 3 known affected families worldwide.

  3. No mutations were identified in COL8A2, in neither the late-onset cohort nor the early-onset family, suggesting genetic heterogeneity in this Late-onset Fuchs endothelial corneal dystrophy (FECD) family.

  4. mutations in the COL8A2 gene do not contribute to all cases of early-onset early-onset Fuchs' endothelial corneal dystrophy .

  5. Variation in the COL8A2, SLC4A11 (zeige SLC4A11 Antikörper), and ZEB1 (zeige ZEB1 Antikörper) genes is present in only a small fraction of African American cases and as such does not appear to significantly contribute to the genetic risk of Fuchs endothelial corneal dystrophy.

  6. Esophageal transcript profiling identified a distinct subset of genes, including COL8A2, in patients with Eosionophilic esophagitis and inherited connective tissue disorders.

  7. Association of central corneal thickness with TCF4 (zeige TCF4 Antikörper) was also significant (p = 6.1x10(-7)), but was abolished with adjustment for FECD grade (p = 0.92).

  8. Single nucleotide polymorphisms in COL8A2 gene is not associated with central corneal thickness in glaucoma.

  9. Report cellular model in which collagen VIII (zeige COX8A Antikörper) mutations, which clinically result in Fuchs' dystrophy, are associated with abnormal cellular accumulation of collagen VIII (zeige COX8A Antikörper).

  10. The purpose of this study is to evaluate COL8A1 (zeige COL8A1 Antikörper) and COL8A2 as candidate genes for thin central corneal thickness in human primary open angle glaucoma patients.

Mouse (Murine) Collagen, Type VIII, alpha 2 (COL8a2) Interaktionspartner

  1. Overexpression of the Col8a2 gene in mouse and human Fuchs endothelial corneal dystrophy endothelial cells suggested a role for altered autophagy in this disease.

  2. in contrast to diabetic wild-type mice EMT (zeige ITK Antikörper)-like changes were attenuated in diabetic Col8alpha1/alpha2-KO mice, indicating that collagen VIII (zeige COX8A Antikörper) may be 1 of the major inducers of epithelial-to-mesenchymal transition-like changes in kidneys of diabetic wild-type mice

  3. study confirms the Q455K substitution in the COL8A2 gene as being sufficient to cause FECD in the first mouse model of this disease and supports the role of the UPR and UPR-associated apoptosis in the pathogenesis of FECD caused by COL8A2 mutations

  4. Type VIII (zeige COX8A Antikörper) collagen significantly modulates the effect of TGF-beta1 (zeige TGFB1 Antikörper) on mesangial cells and may therefore play a role in the pathogenesis of diabetic nephropathy.

  5. Smooth muscle cells can modify the matrix microenvironment by producing type VIII (zeige COX8A Antikörper) collagen, using it to overlay type I collagen, and generating a substrate favorable for migration

  6. Lack of type VIII (zeige COX8A Antikörper) collagen confers renoprotection in diabetic nephropathy in a knockout mouse model.

  7. The mouse mutant Aca23 described here offers the first point mutation of the Col8a2 gene and suggests that a functional collagen VIII (zeige COX8A Antikörper) alpha2 gene is essential for the correct assembly of the Descemet's membrane and for corneal stability.

COL8a2 Antigen-Profil

Protein Überblick

This gene encodes the alpha 2 chain of type VIII collagen. The protein is a major component of the basement membrane of the corneal endothelium and forms homo- or heterotrimers with alpha 1 (VIII) type collagens. Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2.

Genbezeichner und Symbole assoziert mit COL8a2

  • collagen, type VIII, alpha 2 (COL8A2) Antikörper
  • collagen, type VIII, alpha 2 (Col8a2) Antikörper
  • AI429819 Antikörper
  • FECD Antikörper
  • FECD1 Antikörper
  • PPCD Antikörper
  • PPCD2 Antikörper

Bezeichner auf Proteinebene für COL8a2

collagen, type VIII, alpha 2 , collagen alpha-2(VIII) chain , collagen VIII, alpha-2 polypeptide , collagen type VIII alpha 2 , dJ665N4.1 (collagen type VIII alpha 2) , endothelial collagen , procollagen type VIII alpha 2 , procollagen, type VIII, alpha 2

GENE ID SPEZIES
428221 Gallus gallus
539415 Bos taurus
747856 Pan troglodytes
1296 Homo sapiens
329941 Mus musculus
313592 Rattus norvegicus
Ausgewählte Anbieter für anti-COL8a2 (COL8a2) Antikörper
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