Apolipoprotein B Proteine (APOB)

APOB product is the main apolipoprotein of chylomicrons and low density lipoproteins. Zusätzlich bieten wir Ihnen APOB Antikörper (354) und APOB Kits (121) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
APOB 338 P04114
APOB 54225 Q7TMA5
APOB 238055  
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Showing 10 out of 19 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Escherichia coli (E. coli) Wildschwein His tag,GST tag 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
640,00 €
Details
HOST_Human Human Unkonjugiert 500 μg Anmelden zum Anzeigen 6 bis 8 Tage
302,65 €
Details
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
380,95 €
Details
HOST_Escherichia coli (E. coli) Ratte His tag 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
426,67 €
Details
HOST_Escherichia coli (E. coli) Maus His tag 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
579,05 €
Details
Hefe Kaninchen His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.201,74 €
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Hefe Huhn His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
3.057,30 €
Details
HOST_Human Human Unkonjugiert   500 μg Anmelden zum Anzeigen 10 bis 13 Tage
209,87 €
Details
HOST_Human Human Unkonjugiert   0.5 mg Anmelden zum Anzeigen 2 bis 4 Tage
273,43 €
Details

APOB Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
,
Rat (Rattus)

Mouse (Murine)

Weitere Proteine zu Apolipoprotein B (APOB) Interaktionspartnern

Human Apolipoprotein B (APOB) Interaktionspartner

  1. male gender, ageing in women and menopause were associated with increased apoB concentrations.

  2. Data provide no evidence supporting an association between the APOB R3527Q variant and type 2 diabetes or glycemia.

  3. Levels of lipoprotein (a) [Lp(a (zeige APOA Proteine))], a complex between an LDL-like lipid moiety containing one copy of apoB, and apo(a (zeige APOA Proteine)), a plasminogen (zeige PLG Proteine)-derived carbohydrate-rich hydrophilic protein, are primarily genetically rIncreasing evidence suggests that age, sex, and hormonal impact may have a modest modulatory influence on Lp(a (zeige APOA Proteine)) levels. Among clinical conditions, Lp(a (zeige APOA Proteine)) levels are reported to be affected by kidney and liver diseases.

  4. Data suggest that amphipathic beta-strands in 200 N-terminal residues of beta1 domain of APOB are required for secretion of lipid-rich or lipid-poor particles; residues 300-700 or 1050-1500 of beta1 domain appear to be required for secretion of lipid-rich particles; MTTP (zeige MTTP Proteine) is required for secretion of intact APOB but not of truncated APOB. (APOB = apolipoprotein B; MTTP (zeige MTTP Proteine) = microsomal triglyceride transfer protein (zeige MTTP Proteine))

  5. Basal apoB secretion by BeWo cells supports the concept of basal lipoprotein particle secretion by placental syncytiotrophoblast.

  6. ApoB EcoRI confers a moderate risk for coronary heart disease and the E(-) allele at this locus might be a susceptibility allele for the development of disease (Meta-Analysis)

  7. APOB single nucleotide polymorphism and it's association with LDL cholesterol level and risk of coronary heart disease in Pakistani population

  8. Autoantibodies to oxidized lipoproteins and immune complexes with apoB-100 lipoproteins vary significantly by sex, age, and ethnicity. Higher baseline IgG MDA-LDL titers independently associate with new major adverse cardiovascular events.

  9. miR (zeige MLXIP Proteine)-548p regulates apoB secretion by targeting its mRNA degradation.

  10. Adolescent girls with obesity and polycystic ovary syndrome have elevated fasting and postprandial plasma triglycerides and ApoB-lipoprotein remnants.

Cow (Bovine) Apolipoprotein B (APOB) Interaktionspartner

  1. Beyond malabsorption of dietary lipids, deleterious effects of apolipoprotein B deficiency on hepatic lipid metabolism, steroid biosynthesis, and cell membrane function can be expected, which may result in unspecific symptoms of reduced fertility, growth, and health.

  2. Cholesterol deficiency results from a 1.3kbp insertion of an endogenous retrovirus (ERV2-1-LTR_BT) into exon 5 of the APOB gene at BTA11:77,959kb. The insertion is flanked by 6bp target site duplications as described for insertions mediated by retroviral integrases.

  3. A transposable element insertion in APOB causes cholesterol deficiency in Holstein cattle

  4. Nonesterified fatty acids significantly inhibit the expression of ApoB100, ApoE (zeige APOE Proteine), MTP (zeige MTTP Proteine), and LDLR (zeige LDLR Proteine), thereby decreasing the synthesis and assembly of VLDL and inducing TG accumulation in bovine hepatocytes.

  5. after calving the apolipoprotein B(100) mRNA synthesis was lower, whereas microsomal triglyceride transfer protein (MTP (zeige MTTP Proteine)) and apolipoprotein E (zeige APOE Proteine) messenger RNA abundance were higher in the liver.

Mouse (Murine) Apolipoprotein B (APOB) Interaktionspartner

  1. We carried out our experiment in mice deficient in the low density lipoprotein (LDL) receptor (zeige LDLR Proteine) and expressing only ApoB100 molecule (ApoB - LDLr (zeige LDLR Proteine)) where the development of atherosclerosis is known to closely mimic human atherosclerosis

  2. The effect of hypercholesterolemia induced immune response and inflammation on progression of atherosclerosis in ApoB(tm25gy) LDLr (zeige LDLR Proteine)(tm1Her) mice, expressing only ApoB100 and deficient in the low density lipoprotein receptor (zeige LDLR Proteine).

  3. ApoB-containing lipoproteins contribute to augmentation of AngII-induced abdominal aortic aneurysms in male mice.

  4. Immunization with human apolipoprotein B100 (ApoB) resulted in four-fold increased accumulation of effector T cells in ApoB-containing matrigel

  5. PCSK9 (zeige PCSK9 Proteine) markedly increases intestinal triglyceride-rich apoB production through mechanisms mediated in part by transcriptional effects on apoB.

  6. Mice that produce apoB100 in the RPE (zeige RPE Proteine) and liver secrete lipoproteins into Bruch's membrane, but not to the extent that distinct features of AMD (zeige AMD1 Proteine) develop

  7. The aim of this study was to characterize the ocular morphology of low-density lipoprotein receptor-deficient apolipoprotein B-100-only mice, with IGF-II overexpression.

  8. Our data establish the role of APOB gene in severe gut (zeige GUSB Proteine) dysmotility.

  9. Cardiac lipotoxicity may originate from direct inhibition of myocardial ApoB lipoprotein and subsequent decreased lipid export, caused by supraphysiological levels of catecholamines.

  10. ApoB-100 transgenic animals present i) elevated serum and cerebral levels of triglycerides and ApoB-100, ii) increased cerebral tau phosphorylation at phosphosites Ser (zeige SIGLEC1 Proteine)(199), Ser (zeige SIGLEC1 Proteine)(199/202), Ser (zeige SIGLEC1 Proteine)(396) and Ser (zeige SIGLEC1 Proteine)(404).

Pig (Porcine) Apolipoprotein B (APOB) Interaktionspartner

  1. found association between genotypes for LDLR (zeige LDLR Proteine) and APOB polymorphisms and serum lipid levels, but none of them seem to be the causal mutation but probably represent closely linked polymorphisms

APOB Protein Überblick

Protein Überblick

This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels.

Genbezeichner und Symbole assoziert mit Apolipoprotein B Proteine (APOB)

  • apolipoprotein B (APOB)
  • apolipoprotein B (Apob)
  • apolipoprotein B (including Ag(x) antigen) (APOB)
  • Ac1-060 Protein
  • AI315052 Protein
  • APOB Protein
  • ApoB(100) Protein
  • apob-48 Protein
  • APOB-100 Protein
  • Apo B-100 Protein
  • FLDB Protein
  • LDLCQ4 Protein

Bezeichner auf Proteinebene für Apolipoprotein B Proteine (APOB)

apo B-100 , apoB-100 , apoB-48 , apolipoprotein B (including Ag(x) antigen) , apolipoprotein B-100 , apolipoprotein B48 , mutant Apo B 100 , apolipoprotein B PI , apolipoprotein B-48 , apolipoprotein B

GENE ID SPEZIES
338 Homo sapiens
54225 Rattus norvegicus
238055 Mus musculus
494004 Bos taurus
702937 Macaca mulatta
100009101 Oryctolagus cuniculus
100523371 Sus scrofa
396535 Gallus gallus
100725937 Cavia porcellus
475680 Canis lupus familiaris
101107590 Ovis aries
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