Apolipoprotein B Proteine (APOB)

APOB product is the main apolipoprotein of chylomicrons and low density lipoproteins. Zusätzlich bieten wir Ihnen APOB Antikörper (360) und APOB Kits (135) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
APOB 338 P04114
APOB 54225 Q7TMA5
APOB 238055  
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Showing 10 out of 18 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Wildschwein His tag,GST tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
Human Human Unkonjugiert 500 μg Anmelden zum Anzeigen 2 bis 3 Tage
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
Escherichia coli (E. coli) Ratte His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
Escherichia coli (E. coli) Maus His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
Hefe Kaninchen His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
Hefe Huhn His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
Human Human Unkonjugiert Gel Scan of Apolipoprotein B, Human Plasma  This information is representative of the product ART prepares, but is not lot specific. 500 μg Anmelden zum Anzeigen 3 bis 4 Tage
Human Human Unkonjugiert   500 μg Anmelden zum Anzeigen 6 bis 8 Tage

APOB Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
Rat (Rattus)

Mouse (Murine)

Weitere Proteine zu Apolipoprotein B (APOB) Interaktionspartnern

Human Apolipoprotein B (APOB) Interaktionspartner

  1. that apos involved in TG metabolism such as apoC2 (zeige APOC2 Proteine), C3, E, and A4 (micromolar concentration), and apoB48 and apoA5 (zeige APOA5 Proteine) (single-digit nanomolar concentration) can be quantified from a single digestion mixture.

  2. These findings indicate that maternal apo (zeige C9orf3 Proteine) B levels are significantly associated with apo (zeige C9orf3 Proteine) B levels in their pre-school age children, adjusted for confounding variables. Furthermore, the mother-child correlations in apo (zeige C9orf3 Proteine) B levels were independent of mother-child adiposity. Measurement of apo (zeige C9orf3 Proteine) B levels in mothers may identify both high-risk children and mothers who may benefit from intervention.

  3. Individuals with apoB higher than predicted by non-HDL (zeige HSD11B1 Proteine)-C had significantly higher levels of PAI-1 (zeige SERPINE1 Proteine), which may contribute to the increased risk of future atherothrombotic events

  4. analysis of five likely pathogenic heterozygous rare variants that include four novel nonsense mutations in APOB (p.Gln845*, p.Gln2571*, p.Cys2933* and p.Ser3718*) and a rare variant in PCSK9 (zeige PCSK9 Proteine) (Minor Allele Frequency <0.1%).

  5. The impact of smoking on the levels of apolipoprotein B (APOB) was evaluated by analyzing data from NHANES for the years 2007-2012 for US adolescents aged 12-19 years and adults aged greater than or eqult to 20 years. The study found that smoking did not influence the observed levels of APOB for either adolescents or adults.

  6. Identify LDLR (zeige LDLR Proteine), APOB and PCSK9 (zeige PCSK9 Proteine) novel mutations causing familial hypercholesterolemia in the central south region of China.

  7. Rare variants of APOB or PCSK9 (zeige PCSK9 Proteine) were identified in nine of the 22 study patients with extremely low LDL-C levels

  8. Eicosapentaenoic acid has direct antioxidant benefits in various apoB-containing subfractions.

  9. Association of plasma apoB with IR in obese subjects is dependent on gynoid WAT dysfunction

  10. Serum ApoB was not significantly different between term SGA newborns and control term newborns.

Mouse (Murine) Apolipoprotein B (APOB) Interaktionspartner

  1. enhanced VLDL TG secretion in the absence of hepatocyte ABCA1 (zeige ABCA1 Proteine) is due to altered intracellular trafficking of apolipoprotein B (apoB), resulting in augmented TG addition to nascent VLDL.

  2. We carried out our experiment in mice deficient in the low density lipoprotein (LDL) receptor (zeige LDLR Proteine) and expressing only ApoB100 molecule (ApoB - LDLr (zeige LDLR Proteine)) where the development of atherosclerosis is known to closely mimic human atherosclerosis

  3. The effect of hypercholesterolemia induced immune response and inflammation on progression of atherosclerosis in ApoB(tm25gy) LDLr (zeige LDLR Proteine)(tm1Her) mice, expressing only ApoB100 and deficient in the low density lipoprotein receptor (zeige LDLR Proteine).

  4. ApoB-containing lipoproteins contribute to augmentation of AngII-induced abdominal aortic aneurysms in male mice.

  5. Immunization with human apolipoprotein B100 (ApoB) resulted in four-fold increased accumulation of effector T cells in ApoB-containing matrigel

  6. PCSK9 (zeige PCSK9 Proteine) markedly increases intestinal triglyceride-rich apoB production through mechanisms mediated in part by transcriptional effects on apoB.

  7. Mice that produce apoB100 in the RPE (zeige RPE Proteine) and liver secrete lipoproteins into Bruch's membrane, but not to the extent that distinct features of AMD (zeige AMD1 Proteine) develop

  8. The aim of this study was to characterize the ocular morphology of low-density lipoprotein receptor-deficient apolipoprotein B-100-only mice, with IGF-II overexpression.

  9. Our data establish the role of APOB gene in severe gut (zeige GUSB Proteine) dysmotility.

  10. Cardiac lipotoxicity may originate from direct inhibition of myocardial ApoB lipoprotein and subsequent decreased lipid export, caused by supraphysiological levels of catecholamines.

Cow (Bovine) Apolipoprotein B (APOB) Interaktionspartner

  1. Beyond malabsorption of dietary lipids, deleterious effects of apolipoprotein B deficiency on hepatic lipid metabolism, steroid biosynthesis, and cell membrane function can be expected, which may result in unspecific symptoms of reduced fertility, growth, and health.

  2. Cholesterol deficiency results from a 1.3kbp insertion of an endogenous retrovirus (ERV2-1-LTR_BT) into exon 5 of the APOB gene at BTA11:77,959kb. The insertion is flanked by 6bp target site duplications as described for insertions mediated by retroviral integrases.

  3. A transposable element insertion in APOB causes cholesterol deficiency in Holstein cattle

  4. Nonesterified fatty acids significantly inhibit the expression of ApoB100, ApoE (zeige APOE Proteine), MTP (zeige MTTP Proteine), and LDLR (zeige LDLR Proteine), thereby decreasing the synthesis and assembly of VLDL and inducing TG accumulation in bovine hepatocytes.

  5. after calving the apolipoprotein B(100) mRNA synthesis was lower, whereas microsomal triglyceride transfer protein (MTP (zeige MTTP Proteine)) and apolipoprotein E (zeige APOE Proteine) messenger RNA abundance were higher in the liver.

Pig (Porcine) Apolipoprotein B (APOB) Interaktionspartner

  1. found association between genotypes for LDLR (zeige LDLR Proteine) and APOB polymorphisms and serum lipid levels, but none of them seem to be the causal mutation but probably represent closely linked polymorphisms

APOB Protein Überblick

Protein Überblick

This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels.

Genbezeichner und Symbole assoziert mit Apolipoprotein B Proteine (APOB)

  • apolipoprotein B (APOB)
  • apolipoprotein B (Apob)
  • Ac1-060 Protein
  • AI315052 Protein
  • APOB Protein
  • ApoB(100) Protein
  • apob-48 Protein
  • APOB-100 Protein
  • Apo B-100 Protein
  • FLDB Protein
  • LDLCQ4 Protein

Bezeichner auf Proteinebene für Apolipoprotein B Proteine (APOB)

apo B-100 , apoB-100 , apoB-48 , apolipoprotein B (including Ag(x) antigen) , apolipoprotein B-100 , apolipoprotein B48 , mutant Apo B 100 , apolipoprotein B PI , apolipoprotein B-48 , apolipoprotein B

338 Homo sapiens
54225 Rattus norvegicus
238055 Mus musculus
494004 Bos taurus
702937 Macaca mulatta
100009101 Oryctolagus cuniculus
100523371 Sus scrofa
396535 Gallus gallus
100725937 Cavia porcellus
475680 Canis lupus familiaris
101107590 Ovis aries
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