SMAD, Mothers Against DPP Homolog 3 ELISA Kits (SMAD3)
Auf finden Sie aktuell 57 SMAD, Mothers Against DPP Homolog 3 (SMAD3) ELISA Kits von 15 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen SMAD3 Antikörper (515) und SMAD3 Proteine (27) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 642 SMAD3 Produkte verfügbar.
AU022421, HSPC193, HsT17436, JV15-2, LDS1C, LDS3, mad3, Madh3, madh3-A, madh3a, Smad 3, smad3, wu:fa99e03, XenMLP, Xmad3, XSmad3

Weitere ELISA Kits für SMAD3 Interaktionspartner

Zebrafish SMAD, Mothers Against DPP Homolog 3 (SMAD3) Interaktionspartner

  1. Data suggest that Clock1a (zeige CLOCK ELISA Kits) coordinates mesoderm development and primitive hematopoiesis in embryos by up-regulating Nodal-Smad3 signaling; Clock1a (zeige CLOCK ELISA Kits) alterations produce embryonic defects with shortened body length, lack of ventral tail fin, or partial defect of the eyes; Clock1a (zeige CLOCK ELISA Kits) activates Smad3a promoter via its E-box1 element. (Clock1a (zeige CLOCK ELISA Kits) = clock circadian regulator (zeige CLOCK ELISA Kits) a; Nodal = nodal modulator 1 (zeige NOMO1 ELISA Kits); Smad3a = SMAD (zeige SMAD1 ELISA Kits) family member 3a)

  2. Smad3 is mainly active in post-mitotic, non-proliferating cells with a role in TGF-beta (zeige TGFB1 ELISA Kits) control of zebrafish spinal cord development

  3. Nodal signaling and mesendoderm induction depend on Smad2 (zeige SMAD2 ELISA Kits)/3 and suggest that transforming growth factor-beta signals other than Nodal also contribute to Smad2 (zeige SMAD2 ELISA Kits)/3 signaling and embryonic patterning.

  4. although the role of Smad (zeige SMAD1 ELISA Kits) proteins in mediating Nodal signaling is well-documented, the functional characterization of Ttrap (zeige TDP2 ELISA Kits) provides insight into a novel Smad (zeige SMAD1 ELISA Kits) partner that plays an essential role in the fine-tuning of this signal transduction cascade

  5. Smad2 (zeige SMAD2 ELISA Kits)/3 activities play important roles not only in mesendodermal development but also in neural development during early vertebrate embryogenesis

Rabbit SMAD, Mothers Against DPP Homolog 3 (SMAD3) Interaktionspartner

  1. Data indicate that cardiac contractility modulation (CCM) therapy exerted protective effects against myocardial fibrosis potentially by inhibiting TGF-beta1 (zeige TGFB1 ELISA Kits)/Smad3 signaling pathway in chronic heart failure .

  2. study suggested that TGF-beta1/Smad3/smad7 is a major pathway which plays an important role in the regulation of the IUA and specific inhibitor of Smad3 (SIS3) may provide a new therapeutic strategy for IUA.

Human SMAD, Mothers Against DPP Homolog 3 (SMAD3) Interaktionspartner

  1. stablish PPM1A (zeige PPM1A ELISA Kits) as a novel repressor of the SMAD3 pathway in renal fibrosis

  2. Methylation in SMAD3 was selectively increased in asthmatic children of asthmatic mothers and was associated with childhood asthma risk

  3. a direct crosstalk between the STAT3 (zeige STAT3 ELISA Kits) and Smad3 signaling pathways that may contribute to tumor development and inflammation.

  4. It is reported here that TGF-beta (zeige TGFB1 ELISA Kits) directly regulates alternative splicing of cancer stem cell marker CD44 (zeige CD44 ELISA Kits) through a phosphorylated threonine179 of SMAD3-mediated interaction with RNA-binding protein (zeige PTBP1 ELISA Kits) PCBP1 (zeige PCBP1 ELISA Kits).

  5. Bcl-3 (zeige BCL3 ELISA Kits) knockdown enhanced the degradation of Smad3 but not Smad2 (zeige SMAD2 ELISA Kits) following TGFbeta (zeige TGFB1 ELISA Kits) treatment.

  6. miR (zeige MLXIP ELISA Kits)-206 and miR (zeige MLXIP ELISA Kits)-140, as tumor suppressors, induced lung adenocarcinoma cell death and inhibited cell proliferation by modifying oncogenic TRIB2 (zeige TRIB2 ELISA Kits) promoter activity through p-Smad3.

  7. These studies support previously unrecognized, cooperative interaction between the CCN1 (zeige CCNA2 ELISA Kits) matricellular protein and canonical TGF-beta1 (zeige TGFB1 ELISA Kits)/SMAD3 signaling that promotes lung fibrosis.

  8. c-Abl (zeige ABL1 ELISA Kits) promotes TGF-beta (zeige TGFB1 ELISA Kits)-induced SKIP/Smad3 interaction.

  9. Substance P (zeige TAC1 ELISA Kits) can promote hepatic stem cell proliferation and induce HSC (zeige FUT1 ELISA Kits) activation via the TGF-beta1 (zeige TGFB1 ELISA Kits)/Smad3 signaling pathway.

  10. High SMAD3 expression is associated with increased lung adenocarcinoma.

Xenopus laevis SMAD, Mothers Against DPP Homolog 3 (SMAD3) Interaktionspartner

  1. E2a (zeige TCF3 ELISA Kits) is necessary to drive transcription of Smad2 (zeige SMAD2 ELISA Kits)/3 target genes, including critical regulators of dorsal cell fate and morphogenesis

Pig (Porcine) SMAD, Mothers Against DPP Homolog 3 (SMAD3) Interaktionspartner

  1. Activin A (zeige INHBA ELISA Kits) and overexpression of SMAD2 (zeige SMAD2 ELISA Kits)/3 significantly promoted expressions of porcine NANOG (zeige NANOG ELISA Kits) and OCT4 (zeige POU5F1 ELISA Kits),maintaining induced pluripotent stem cell self-renewal through up-regulation of Nanog (zeige NANOG ELISA Kits)/OCT4 (zeige POU5F1 ELISA Kits) expression.

  2. Smad3 regulate the activity and stability of myocardin (zeige MYOCD ELISA Kits)-related transcription factor during epithelial-myofibroblast transition

  3. SP1 (zeige SP1 ELISA Kits) and SMAD3 are required for high glucose-induced p21(WAF1 (zeige CDKN1A ELISA Kits)) gene transcription in LLC-PK1 (zeige PKLR ELISA Kits) cells.

Mouse (Murine) SMAD, Mothers Against DPP Homolog 3 (SMAD3) Interaktionspartner

  1. Data suggest that Gas5 suppresses Tgfb1 (zeige TGFB1 ELISA Kits)/Smad3 signaling in vascular smooth muscle cell differentiation from mesenchymal progenitor cells; Gas5 competitively binds Smad3 via multiple RNA Smad (zeige SMAD1 ELISA Kits)-binding elements. (Gas5 = growth arrest-specific 5 long non-coding RNA; Tgfb1 (zeige TGFB1 ELISA Kits) = transforming growth factor beta 1 (zeige TGFB1 ELISA Kits); Smad3 = MAD homolog 3 protein)

  2. point mutant that was unable to bind pSMAD3 proved ineffective. These findings indicate that specifically targeting pSMAD3 can ameliorate both the direct and indirect fibroproliferative actions of TGF-beta (zeige TGFB1 ELISA Kits).

  3. Soluble epoxide hydrolase (zeige EPHX2 ELISA Kits) inhibitor AUDA decreases bleomycin-induced pulmonary toxicity in mice by inhibiting the p38 (zeige CRK ELISA Kits)/Smad3 signaling pathway.

  4. A critical role for the Smad3-c-Jun (zeige JUN ELISA Kits) pathway in the regulation of Fstl1 (zeige FSTL1 ELISA Kits).

  5. Mirtazapine suppressed 5-HT (zeige DDC ELISA Kits)-mediated TGF-beta1 (zeige TGFB1 ELISA Kits)/Smad3 and ERK1/2 (zeige MAPK1/3 ELISA Kits) signaling pathways as well as oxidative stress that contribute to the progression of liver fibrosis.

  6. These results suggest that Nedd9 (zeige NEDD9 ELISA Kits) is a Smad2 (zeige SMAD2 ELISA Kits)/3 target gene implicated in RANKL (zeige TNFSF11 ELISA Kits)-induced osteoclastogenesis.

  7. These results suggested that TGF-beta1 (zeige TGFB1 ELISA Kits)/Smad3 signaling was activated during CCl4 (zeige CCL4 ELISA Kits)-induced acute liver injury in mice, and Smad3 overexpression aggravated acute liver injury by promoting inflammatory cells infiltration, inflammatory cytokines release and hepatocytes apoptosis.

  8. gonadotropin-releasing hormone receptor (zeige GNRHR ELISA Kits) mRNA levels were significantly elevated in knock-outs in both sexes. Interestingly, luteinizing hormone production was altered in a sex-specific fashion. Overall, our analyses demonstrate that SMAD3 is required for FSH (zeige BRD2 ELISA Kits) synthesis in vivo

  9. Evaluated the effects of the loss of Smad3 on the development of experimental argon laser-induced choroidal neovascularization (CNV). The size of the CNV induced was significantly smaller in KO mice as compared with WT mice at day 14.

  10. hese studies revealed that Smad2 (zeige SMAD2 ELISA Kits) plays an essential role in the development of the growth plate, that both Smads 2 and 3 inhibit Ihh (zeige IHH ELISA Kits) expression in the neonatal growth plate, and suggested they accomplish this by binding to distinct SBEs, mediating assembly of distinct repressive complexes.

Cow (Bovine) SMAD, Mothers Against DPP Homolog 3 (SMAD3) Interaktionspartner

  1. the present work provides evidence supporting a functional role of SMAD2 (zeige SMAD2 ELISA Kits)/3 in bovine early embryogenesis

  2. Mechanical compression not only with physiological but also with excessive stress can activate Smad2 (zeige SMAD2 ELISA Kits)/3P signaling, which is known to be protective for articular cartilage and to block chondrocyte terminal differentiation.

  3. a detailed computational model for TGF-beta (zeige TGFB1 ELISA Kits) signalling that incorporates elements of previous models together with crosstalking between Smad1 (zeige SMAD1 ELISA Kits)/5/8 and Smad2 (zeige SMAD2 ELISA Kits)/3 channels through a negative feedback loop dependent on Smad7 (zeige SMAD7 ELISA Kits).

SMAD3 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.

Alternative names and synonyms associated with SMAD3

  • SMAD family member 3 (SMAD3) Elisa Kit
  • MAD homolog 3a (Drosophila) (smad3a) Elisa Kit
  • mothers against decapentaplegic homolog 3 (LOC100346303) Elisa Kit
  • SMAD family member 3 (smad3) Elisa Kit
  • SMAD family member 3 (Smad3) Elisa Kit
  • AU022421 Elisa Kit
  • HSPC193 Elisa Kit
  • HsT17436 Elisa Kit
  • JV15-2 Elisa Kit
  • LDS1C Elisa Kit
  • LDS3 Elisa Kit
  • mad3 Elisa Kit
  • Madh3 Elisa Kit
  • madh3-A Elisa Kit
  • madh3a Elisa Kit
  • Smad 3 Elisa Kit
  • smad3 Elisa Kit
  • wu:fa99e03 Elisa Kit
  • XenMLP Elisa Kit
  • Xmad3 Elisa Kit
  • XSmad3 Elisa Kit

Bezeichner auf Proteinebene für SMAD3

MAD homolog 3 , MAD homolog 3a , MAD, mothers against decapentaplegic homolog 3 , SMA- and MAD-related protein 3 , SMAD, mothers against DPP homolog 3 , hMAD-3 , hSMAD3 , mad homolog JV15-2 , mad protein homolog , mad3 , mothers against DPP homolog 3 , mothers against decapentaplegic homolog 3 , SMAD 3 , TGF beta response effector Smad3 , TGF-beta response effector Smad3 , Smad 3 , mMad3 , MAD (mothers against decapentaplegic, Drosophila) homolog 3 , SMAD family member 3

100033845 Equus caballus
58092 Danio rerio
100346303 Oryctolagus cuniculus
4088 Homo sapiens
378633 Xenopus laevis
395132 Gallus gallus
610902 Canis lupus familiaris
397260 Sus scrofa
17127 Mus musculus
25631 Rattus norvegicus
515125 Bos taurus
100731807 Cavia porcellus
443169 Ovis aries
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