beta-Transducin Repeat Containing ELISA Kits (BTRC)
Auf finden Sie aktuell 14 beta-Transducin Repeat Containing (BTRC) ELISA Kits von 2 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen BTRC Antikörper (49) und BTRC Proteine (3) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 69 BTRC Produkte verfügbar.
b-TrCP, BETA-TRCP, Beta-Trcp1, betaTrCP, btrc, btrc-a, bTrCP, bTrCP1, Fbw1a, FBXW1, FBXW1A, FWD1, HOS, mKIAA4123, Slimb

Weitere ELISA Kits für BTRC Interaktionspartner

Xenopus laevis beta-Transducin Repeat Containing (BTRC) Interaktionspartner

  1. Strong ERK (zeige MAPK1 ELISA Kits) activation can target Cdc25A (zeige CDC25A ELISA Kits) for degradation in a manner similar to, but independent of, Chk1 (zeige CHEK1 ELISA Kits) for cell cycle arrest.

Human beta-Transducin Repeat Containing (BTRC) Interaktionspartner

  1. It demonstrates that degradation of Lipin-1 (zeige LPIN1 ELISA Kits) is regulated by BTRC in the cytoplasm and on membranes

  2. we identified two independent SNPs (i.e., WNT2B (zeige WNT2B ELISA Kits) rs1175649 G>T and BTRC rs61873997 G>A) that showed a predictive role in CM-specific survival, with an effect-allele-attributed hazards ratio (adjusted hazards ratio) of 1.99 (95% confidence interval = 1.41-2.81, P = 8.10 x 10(-5)) and 0.61 (0.46-0.80, 3.12x10(-4)), respectively.

  3. It has been proposed that CENP-W (zeige CENPW ELISA Kits) may function as a booster of beta-TrCP1 nuclear import to increase the oncogenicity of beta-TrCP1.

  4. oncogenic effect of miR (zeige MLXIP ELISA Kits)-182 and its reversal by beta-TrCP2 were confirmed in vivo This study suggests that beta-TrCP and miR (zeige MLXIP ELISA Kits)-182 may be possible biomarkers and targets for early detection and treatment of pancreatic cancer

  5. Beta-TrCP controls ubiquitination and degradation of liver-enriched transcription factor CREB-H (zeige CREB3L3 ELISA Kits).

  6. Phosphorylated VEGFR-2 (zeige KDR ELISA Kits) was reduced by hyperglycemia while total VEGFR-2 (zeige KDR ELISA Kits) was almost unaltered. However, VEGFR-2 (zeige KDR ELISA Kits) was reduced when directly exposed to reactive oxygen species, with resultant co-location of beta-TrCP and VEGFR-2 (zeige KDR ELISA Kits).

  7. Low GAS7C increases cancer cell motility by promoting N-WASP (zeige WASL ELISA Kits)/FAK (zeige PTK2 ELISA Kits)/F-actin cytoskeleton dynamics. It also enhances beta-catenin (zeige CTNNB1 ELISA Kits) stability via hnRNP U (zeige HNRNPU ELISA Kits)/beta-TrCP complex formation.

  8. EBV-miR (zeige MLXIP ELISA Kits)-BART10-3p facilitated epithelial-mesenchymal transition and promotes metastasis of nasopharyngeal carcinoma by targeting BTRC.

  9. beta-TrCP1/FWD1 dominant negative mutant has a role in reducing myeloma cell growth

  10. This study showed SCF (zeige KITLG ELISA Kits)(beta-TRCP) earmarks Set8 (zeige SETD8 ELISA Kits) for ubiquitination and degradation in a casein kinase I (zeige CSNK1D ELISA Kits)-dependent manner, which is activated by DNA-damaging agents.

Mouse (Murine) beta-Transducin Repeat Containing (BTRC) Interaktionspartner

  1. betaTrCP levels are correlated with imiquimod-induced skin lesion.

  2. beta-TrCP1/FWD1 dominant negative mutant has a role in reducing myeloma cell growth

  3. Erbin (zeige ERBB2IP ELISA Kits) as a novel substrate of SAG (zeige RNF7 ELISA Kits)-betaTrCP E3 ligase.

  4. these results clearly suggest that both beta-TrCP- and Hrd1 (zeige SYVN1 ELISA Kits)-dependent degradation mechanisms regulate the transcriptional activity of Nrf1 (zeige NRF1 ELISA Kits) to maintain cellular homeostasis.

  5. beta-TrCP may be an essential player in UVB induced responses in skin

  6. Glycogen synthase kinase 3 (zeige GSK3a ELISA Kits) phosphorylates a group of Ser (zeige SIGLEC1 ELISA Kits) residues in the Neh6 domain of mouse Nrf2 (zeige NFE2L2 ELISA Kits) that overlap with an SCF (zeige KITLG ELISA Kits)/beta-TrCP destruction motif (DSGIS, residues 334 to 338) and promotes its degradation in a Keap1 (zeige KEAP1 ELISA Kits)-independent manner.

  7. LPS (zeige TLR4 ELISA Kits) appears to destabilize the LPCAT1 (zeige LPCAT1 ELISA Kits) protein by GSK-3beta (zeige GSK3b ELISA Kits)-mediated phosphorylation within a canonical phosphodegron for beta-TrCP docking and site-specific ubiquitination.

  8. the two beta-TrCP paralogs have a nonredundant role in spermatogenesis

  9. anti-inflammatory effects of H(2)O(2) may result from its ability to decrease ubiquitination as well as subsequent degradation of I kappaB alpha through inhibiting the association between I kappaB alpha and SCF (zeige KITLG ELISA Kits)(beta-TrCP)

  10. BMP-2 (zeige BMP2 ELISA Kits) modulates beta-catenin (zeige CTNNB1 ELISA Kits) signaling through stimulation of Lrp5 (zeige LRP5 ELISA Kits) expression and inhibition of beta-TrCP expression in osteoblasts

BTRC Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class\; in addition to an F-box, this protein contains multiple WD-40 repeats. The encoded protein mediates degradation of CD4 via its interaction with HIV-1 Vpu. It has also been shown to ubiquitinate phosphorylated NFKBIA (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha), targeting it for degradation and thus activating nuclear factor kappa-B. Alternatively spliced transcript variants have been described. A related pseudogene exists in chromosome 6.

Alternative names and synonyms associated with BTRC

  • beta-transducin repeat containing (BTRC) Elisa Kit
  • beta-transducin repeat containing E3 ubiquitin protein ligase (BTRC) Elisa Kit
  • beta-transducin repeat containing E3 ubiquitin protein ligase (btrc) Elisa Kit
  • beta-transducin repeat containing (btrc) Elisa Kit
  • beta-transducin repeat containing E3 ubiquitin protein ligase (Btrc) Elisa Kit
  • beta-transducin repeat containing protein (Btrc) Elisa Kit
  • b-TrCP Elisa Kit
  • BETA-TRCP Elisa Kit
  • Beta-Trcp1 Elisa Kit
  • betaTrCP Elisa Kit
  • btrc Elisa Kit
  • btrc-a Elisa Kit
  • bTrCP Elisa Kit
  • bTrCP1 Elisa Kit
  • Fbw1a Elisa Kit
  • FBXW1 Elisa Kit
  • FBXW1A Elisa Kit
  • FWD1 Elisa Kit
  • HOS Elisa Kit
  • mKIAA4123 Elisa Kit
  • Slimb Elisa Kit

Bezeichner auf Proteinebene für BTRC

beta-transducin repeat containing , beta-transducin repeat containing protein , F-box/WD repeat-containing protein 1A , f-box/WD repeat-containing protein 1A-like , E3RSIkappaB , F-box and WD repeats protein beta-TrCP , F-box and WD-repeat protein 1B , beta-TrCP1 , epididymis tissue protein Li 2a , pIkappaBalpha-E3 receptor subunit , beta-TrCP , beta-transducin repeat-containing protein , SCF b-TRCP , beta-TrCP protein E3RS-IkappaB , mE3RS-IkappaB , pIkappaB-E3 receptor subunit , ubiquitin ligase FWD1

423854 Gallus gallus
450685 Pan troglodytes
486851 Canis lupus familiaris
534072 Bos taurus
549140 Xenopus (Silurana) tropicalis
100171847 Pongo abelii
100337561 Xenopus laevis
100470916 Ailuropoda melanoleuca
100157842 Sus scrofa
100634006 Amphimedon queenslandica
8945 Homo sapiens
361765 Rattus norvegicus
394362 Xenopus laevis
100350519 Oryctolagus cuniculus
100730107 Cavia porcellus
101101939 Ovis aries
12234 Mus musculus
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