CAMK2A Proteine (CAMK2A)

Bezeichnung:
Calcium/calmodulin-Dependent Protein Kinase II alpha Proteine (CAMK2A)
Auf www.antikoerper-online.de finden Sie aktuell 11 Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) Proteine von 6 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen CAMK2A Antikörper (189) und CAMK2A Kits (22) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 233 CAMK2A Produkte verfügbar.
Synonyme:
camk2, camk2b, CAMKA, CaMKII, mKIAA0968, PK2CDD, PKCCD, R74975, zgc:112538, zgc:123320
alle Proteine anzeigen Gen GeneID UniProt
CAMK2A 815 Q9UQM7
CAMK2A 12322 P11798
CAMK2A 25400 P11275

Weitere Synonyme anzeigen

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Am meisten referenzierte CAMK2A Proteine

  1. Human CAMK2A Protein expressed in Baculovirus infected Insect Cells - ABIN2003179 : Schmutz, Martin, Terry, Couronne, Grimwood, Lowry, Gordon, Scott, Xie, Huang, Hellsten, Tran-Gyamfi, She, Prabhakar, Aerts, Altherr, Bajorek, Black, Branscomb, Caoile, Challacombe, Chan, Denys et al.: The DNA sequence and comparative analysis of human chromosome 5. ... in Nature 2004 (PubMed)
    Zeige alle 3 Referenzen für 2003179

Weitere Proteine zu CAMK2A Interaktionspartnern

Xenopus laevis Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) Interaktionspartner

  1. These findings uncover a direct mechanism of CaMKII (zeige CAMK2G Proteine) regulation by metabolism and further highlight the importance of metabolism in preserving oocyte viability.

  2. analysis of metabolic regulation of CaMKII (zeige CAMK2G Proteine) protein and caspases in Xenopus laevis egg extracts

  3. Characterization of a central Ca2 (zeige CA2 Proteine)+/calmodulin (zeige Calm2 Proteine)-dependent protein kinase (zeige CSNK1D Proteine) IIalpha/beta binding domain in densin that selectively modulates glutamate (zeige GRIN2A Proteine) receptor subunit phosphorylation.

Human Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) Interaktionspartner

  1. This study demonstrate that this ASD (zeige ARSD Proteine)-linked de novo CAMK2A mutation disrupts multiple CaMKII (zeige CAMK2G Proteine) functions, induces synaptic deficits, and causes ASD (zeige ARSD Proteine)-related behavioral alterations.

  2. CaMKII (zeige CAMK2G Proteine)-mediated recruitment and upregulation of CYLD (zeige CYLD Proteine) is expected to remove K63-linked polyubiquitins and facilitate proteasomal degradation at the postsynaptic density.

  3. CAMK2A SNPs were associated with Alzheimer disease and mild cognitive impairment. AG genotype at the CAMK2A-rs3822606 was associated with AD risk.

  4. CaMKII (zeige CAMK2G Proteine) phosphorylates SCN5A (zeige SCN5A Proteine) in vitro on 23 novel serine sites as was identified by mass spectrometry; reduced S516 phosphorylation has been found in human heart failure.

  5. Ca2+/calmodulin-dependent protein kinase-II (CaMKII) has a key role in the plasticity of glutamatergic synapses of the brain.

  6. we describe for the first time, two patients with MFD (zeige SCYL1 Proteine) and ID and for whom a deletion encompassing TCOF1 (zeige TCOF1 Proteine) and CAMK2A has been identified

  7. a novel regulation of CaMKII (zeige CAMK2G Proteine) by another second messenger system and indicate its involvement in excitotoxic neuronal cell death.

  8. Overexpression of a T253D phosphomimic form of calcium/calmodulin-dependent protein kinase type II subunit alpha significantly decreases proliferation, and cells accumulate in mitosis, specifically in metaphase.

  9. results suggest that the CAMK2A gene may influence spatial and non-SWM performance in humans without any corresponding gross changes in frontal cortex or hippocampal anatomy.

  10. found seven significant associations between CAMK2A SNPs and alcohol dependence, one of which in an autophosphorylation-related area of the gene.

Mouse (Murine) Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) Interaktionspartner

  1. Destabilization of PGC1a is attributable to decreased p38 MAPK (zeige MAPK14 Proteine) activation via diminished CaMKII (zeige CAMK2G Proteine) signaling. Thus, we elucidate a pathway downstream of Ca(2 (zeige CA2 Proteine)+)-mediated CaMKII (zeige CAMK2G Proteine) activation that is dysfunctional in C3KO(Capn3 (zeige CAPN3 Proteine) knock-out mice ) mice, leading to reduced transcription of genes involved in muscle adaptation

  2. In young mice, 30% of adult CaMKIIalpha expression is sufficient for normal long-term potentiation in the hippocampus and cerebral cortex.

  3. Findings demonstrate that Thr286 phosphorylation of CaMKII (zeige CAMK2G Proteine) plays an important role in induction of long-term potentiation (LTP (zeige SCP2 Proteine)) by integrating Ca(2 (zeige CA2 Proteine)+) signals, and it greatly promotes, but is dispensable for, the activation of CaMKII (zeige CAMK2G Proteine) and LTP (zeige SCP2 Proteine).

  4. The present study demonstrates, for the first time, that ROS (zeige ROS1 Proteine)-dependent activation of CaMKII (zeige CAMK2G Proteine) mediates altered Ca2 (zeige CA2 Proteine)+ handling and contractile dysfunction observed in the setting of sepsis.

  5. Thus, taken into consideration the mechanism that controls the upregulation of maturation genes involved in synaptic formation, these results indicate that Etv1 (zeige ETV1 Proteine) orchestrates the activity-dependent regulation of both maturation and immaturation genes in developing granule cells and plays a key role in specifying the identity of mature granule cells in the cerebellum.

  6. Pharmacological and genetic studies using CaMKII (zeige CAMK2G Proteine) antagonists and genetically modified [alpha]-CaMKII (zeige CAMK2G Proteine) mice have shown that blockade or reduction of CaMKII (zeige CAMK2G Proteine) reduces nicotine reward

  7. The study shows advanced glycation end products (AGEs) resulted from ribosylation activate calcium-/calmodulin-dependent protein kinase type II (CaMKII (zeige CAMK2G Proteine)), a key kinase responsible for Tau hyperphosphorylation.

  8. HDAC2 (zeige HDAC2 Proteine) may regulate the expression of immediate early (zeige JUN Proteine) genes, in part, by prolonging the actions of pCREB in the mouse nucleus accumbens.

  9. The results suggest that CaMKII (zeige CAMK2G Proteine)-dependent TnI (zeige TNNI2 Proteine) phosphorylation is involved in FDMCD and the consequent FDAR and that CaMKII (zeige CAMK2G Proteine) inhibition removes this mechanism and thus induces diastolic dysfunction.

  10. Results indicate that alpha-Ca(2+)/calmodulin-dependent protein kinase II overexpression in the forebrain impairs behavioral flexibility and NMDAR (zeige GRIN1 Proteine)-dependent long-term depression in the medial prefrontal cortex.

Rabbit Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) Interaktionspartner

  1. We conclude that ouabain, even at low concentrations (0.5-8.0 mum), can increase INaL and reverse INCX , and these effects may contribute to the effect of the glycoside to increase Ca(2 (zeige CA2 Proteine)+) transients and contractility.

  2. Data indicate that nitric oxide directly affects Ca-calmodulin (zeige CALM Proteine)-dependent protein kinase (zeige CDK7 Proteine) (CaMKII (zeige CAMK2G Proteine)) to sustain its activity leading to the increase in sarcoplasmic reticulum calcium leak.

  3. Data indicate that the CaMKII (zeige CAMK2G Proteine) inhibitor, KN-93, can inhibit early afterdepolarizations (EADs), resulting in the suppression of torsades de pointes (TDP) induced by long-QT (LQT (zeige ARFGAP1 Proteine)) syndrome without affecting transmural dispersion of repolarization (TDR).

  4. CaMKII (zeige CAMK2G Proteine) signaling, a crucial element of normal automaticity in rabbit sinoatrial node cells (SANC), is also involved in SANC bioenergetics.

CAMK2A Protein Überblick

Protein Überblick

The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene.

Alternative names and synonyms associated with CAMK2A

  • calcium/calmodulin-dependent protein kinase II alpha (CAMK2A)
  • calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha (camk2a)
  • calcium/calmodulin-dependent protein kinase II alpha (Camk2a)
  • camk2 Protein
  • camk2b Protein
  • CAMKA Protein
  • CaMKII Protein
  • mKIAA0968 Protein
  • PK2CDD Protein
  • PKCCD Protein
  • R74975 Protein
  • zgc:112538 Protein
  • zgc:123320 Protein

Bezeichner auf Proteinebene für CAMK2A

calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha , calcium/calmodulin-dependent protein kinase II beta , calmodulin dependent protein kinase II beta subunit , calcium/calmodulin-dependent protein kinase II alpha , calcium/calmodulin-dependent protein kinase type II subunit alpha , camk2a1 , CaM kinase II alpha subunit , CaM-kinase II alpha chain , CaMK-II alpha subunit , CaMKIINalpha , caM kinase II subunit alpha , caMK-II subunit alpha , calcium/calmodulin-dependent protein kinase II alpha-B subunit , calcium/calmodulin-dependent protein kinase type II alpha chain , CaMK II , alpha-CaMKII , Ca2+/calmodulin-dependent protein kinase II alpha , alpha CaM kinase II , caM-kinase II alpha chain , calcium/calmodulin-dependent protein kinase II alpha subunit , calcium/calmodulin-dependent protein kinase type II alpha , Calcium/calmodulin-dependent protein kinase type II alpha chain , calcium/calmodulin-dependent protein kinase IIA

GENE ID SPEZIES
462189 Pan troglodytes
399284 Xenopus laevis
550436 Danio rerio
815 Homo sapiens
12322 Mus musculus
25400 Rattus norvegicus
374175 Gallus gallus
530719 Bos taurus
612941 Canis lupus familiaris
100341507 Oryctolagus cuniculus
100727059 Cavia porcellus
100172212 Pongo abelii
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