Podocalyxin-Like Proteine (PODXL)

Bezeichnung:
Podocalyxin-Like Proteine (PODXL)
Auf www.antikoerper-online.de finden Sie aktuell 32 Podocalyxin-Like (PODXL) Proteine von 8 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Podocalyxin-Like Antikörper (349) und Podocalyxin-Like Kits (48) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 436 Podocalyxin-Like Produkte verfügbar.
Synonyme:
AW121214, cPCLP1, fc18d02, Gp135, Gp200, Ly102, MEP21, PC, PCLP, PCLP-1, PCLP1, podocalyxin, Podxl, wu:fc18d02
alle Proteine anzeigen Gen GeneID UniProt
PODXL 5420 O00592
PODXL 27205 Q9R0M4
PODXL 192181 Q9WTQ2

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Weitere Proteine zu Podocalyxin-Like Interaktionspartnern

Human Podocalyxin-Like (PODXL) Interaktionspartner

  1. PODXL enhances motility and invasiveness through an increase in gelsolin-actin interactions in cell protrusions.

  2. Results identify an anti-metastatic miRNA, miR (zeige MLXIP Proteine)-5100, that decreases the metastatic ability of pancreatic cancer partially by suppressing expression of PODXL.

  3. Results indicate that urinary podocalyxin is not only an early marker but also a treatment target for diabetic nephropathy (DN).

  4. Obese subjects showed evidence of renal alteration through the detection of a higher number of urinary podocalyxin positive cells.

  5. Data show that both mucin16 (MUC16 (zeige MUC16 Proteine)) and podocalyxin (PODXL)-E-selectin (zeige SELE Proteine)-mediated interactions are mechanically stronger than like L-selectin (zeige SELL Proteine) interactions at the single-molecule level.

  6. In gastric cancer, PODXL expression by the polyclonal antibody HPA2110 is an independent marker of poor prognosis.

  7. PCX (zeige PC Proteine) promotes cisplatin chemoresistance in osteosarcoma cells through a PI3Kdependent mechanism.

  8. EZR (zeige EZR Proteine), CLIC5 (zeige CLIC5 Proteine) and PODXL are overexpressed in hepatocellular carcinoma and may have a role in cell migration and invasiveness

  9. PODXL up-regulates the expression level of Bmi1 (zeige BMI1 Proteine) in OTSCC cells.

  10. podocalyxin to be an independent factor for poor prognosis in PDAC. To our knowledge, this is the first such report of its prognostic value.

Mouse (Murine) Podocalyxin-Like (PODXL) Interaktionspartner

  1. Podxl-overexpression in neural stem/progenitor cells leads to an up-regulation of Annexin A2 (zeige ANXA2 Proteine).

  2. when endogenous podocalyxin was removed from highly metastatic 4T1 mammary tumor cells there was a decrease in collective invasion . Podocalyxin is a tumor cell-intrinsic regulator of experimental collective tumor cell invasion and tumor budding.

  3. Podocalyxin has a role in glioblastoma multiforme cell invasion and proliferation via beta-catenin (zeige CTNNB1 Proteine) signaling

  4. Loss of podocalyxin from the lung vasculature results in changes to the lung structure and function including increased lung volume when inflated under constant pressure (25 cm H2O) and changes to the matrix composition.

  5. CTGF is an important mediator of high glucose-induced podocyte damage and decreases the protein level of podocalyxin by the ERK1/2 pathway.

  6. platelet Podxl is involved in the control of hemostasis acting as a platelet co-stimulator, likely due to its pro-adhesive properties

  7. Full-length recombinant murine podocalyxin recruits NHERF-1 (zeige SLC9A3R1 Proteine) to the apical domain. Ectopic expression in human & canine epithelial cells leads to microvilli formation on an apical domain extending laterally to the junctional complexes.

  8. Podocalyxin plays multiple roles in neural development

  9. PODXL may act as a costimulator of agonists in the activation of platelets and formation of a stable thrombus.

  10. Data show that in podocalyxin-deficient mice, the thickness of the main carotid artery is significantly increased, and there is an increased number of choroidal capillaries lining the ventricular spaces.

Podocalyxin-Like (PODXL) Protein Überblick

Protein Überblick

This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.

Alternative names and synonyms associated with Podocalyxin-Like (PODXL)

  • podocalyxin-like (PODXL)
  • si:dkey-146n1.1 (si:dkey-146n1.1)
  • podocalyxin-like (LOC100614602)
  • podocalyxin-like (Podxl)
  • podocalyxin-like (LOC100512201)
  • podocalyxin-like protein 1 (PCLP1)
  • AW121214 Protein
  • cPCLP1 Protein
  • fc18d02 Protein
  • Gp135 Protein
  • Gp200 Protein
  • Ly102 Protein
  • MEP21 Protein
  • PC Protein
  • PCLP Protein
  • PCLP-1 Protein
  • PCLP1 Protein
  • podocalyxin Protein
  • Podxl Protein
  • wu:fc18d02 Protein

Bezeichner auf Proteinebene für Podocalyxin-Like Proteine (PODXL)

podocalyxin-like , podocalyxin-like protein 1-like , GCTM-2 antigen , podocalyxin , podocalyxin-like protein 1 , PC-like protein 1 , Podocalyxin-like protein 1 , thrombomucin

GENE ID SPEZIES
472604 Pan troglodytes
563365 Danio rerio
100462597 Pongo abelii
100614602 Pan troglodytes
5420 Homo sapiens
27205 Mus musculus
192181 Rattus norvegicus
482252 Canis lupus familiaris
100727578 Cavia porcellus
395755 Gallus gallus
616366 Bos taurus
101106679 Ovis aries
100512201 Sus scrofa
100009552 Oryctolagus cuniculus
Ausgewählte Anbieter für Podocalyxin-Like Proteine (PODXL)
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