TNFAIP3 Proteine (TNFAIP3)

Bezeichnung:
Tumor Necrosis Factor, alpha-Induced Protein 3 Proteine (TNFAIP3)
Auf www.antikoerper-online.de finden Sie aktuell 9 Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) Proteine von 5 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TNFAIP3 Antikörper (92) und TNFAIP3 Kits (9) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 116 TNFAIP3 Produkte verfügbar.
Synonyme:
A20, MGC82339, OTUD7C, TNFA1P2, TNFAIP3, Tnfip3
alle Proteine anzeigen Gen GeneID UniProt
TNFAIP3 7128 P21580
TNFAIP3 21929 Q60769
TNFAIP3 683206  

Weitere Synonyme anzeigen

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Weitere Proteine zu TNFAIP3 Interaktionspartnern

Human Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) Interaktionspartner

  1. this meta-analysis confirms that TNFAIP3 gene polymorphisms may play important roles in the pathogenesis of Rheumatoid arthritis

  2. Report a significant association between the biased usage of IGHV4-34 (binds to the carbohydrate I/i antigens) and inactivating mutation of TNFAIP3 [encoding a global negative regulator of the canonical nuclear factor-kappaB (NF-kappaB (zeige NFKB1 Proteine)) pathway] in ocular adnexal MALT lymphomas.

  3. TNFAIP3 rs10499194 T allele and CT genotype were associated with an increased risk for AIH-1 (zeige AMELX Proteine)

  4. Haploinsufficiency of TNFAIP3 (A20) by a germline heterozygous mutation leads to the autoimmune lymphoproliferative syndrome (ALPS) phenotype.

  5. These results suggested that A20 is involved in regulating intracerebral hemorrhage-induced inflammatory injury in both the central and peripheral system

  6. In targeted sequencing, a disruptive mutation of TNFAIP3 was the most common alteration (54%), followed by mutations of TBL1XR1 (zeige TBL1XR1 Proteine) (18%) and cAMP response element binding proteins (CREBBP (zeige CREBBP Proteine)) (17%).

  7. the DNA fragment containing the associated SNPs interacts through chromatin looping not only with TNFAIP3, but also with IL20RA (zeige IL20RA Proteine), located 680 kb upstream.

  8. The findings suggest that TNFAIP3 protein may be an independent prognostic marker for poor survival, and a promising target for esophageal squamous cell carcinoma therapy.

  9. Study demonstrates that the rs7749323 in the TNFAIP3 gene is strongly associated with the late onset myasthenia gravis(with positive AChR Ab but without thymoma).

  10. Influenza a virus NS1 (zeige PTPN11 Proteine) has a role in inducing A20 contributes to viral replication by suppressing interferon (zeige IFNA Proteine)-induced antiviral response

Mouse (Murine) Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) Interaktionspartner

  1. These results suggested that A20 is involved in regulating intracerebral hemorrhage-induced inflammatory injury in both the central and peripheral system

  2. the ubiquitin-modifying enzyme TNFAIP3/A20, an upstream regulator of T cell receptor (TCR) signaling in T cells, is an essential cell-intrinsic regulator of Natural killer T differentiation.

  3. these data reveal a crucial role of A20 in regulating the immunomodulatory activities of mesenchymal stem cells.

  4. Therefore, A20 acts as a novel endogenous regulator of STAT1 (zeige STAT1 Proteine) that prevents onset of enthesitis.

  5. This study demonstrated that miR (zeige MLXIP Proteine)-136-5p affected the expression of A20 in IL-17 (zeige IL17A Proteine)-stimulated astrocytes.

  6. Our data suggest that NAOs have a beneficial preventive effect in septic shock correlated with the enhancement of IL-10 (zeige IL10 Proteine) via the induction of A20 and COX-2.

  7. Forced expression of A20 resulted in decreased expression of key markers of lipogenesis and adipogenesis, such as sterol regulatory element binding protein (zeige CNBP Proteine) 1c (SREBP-1c (zeige SREBF1 Proteine)) and adipogenesis (aP2 (zeige TFAP2A Proteine)), leading to less lipids accumulation in differentiated 3T3-L1 cells

  8. these results suggest that Mycobacterium fortuitum-induced activation of host proinflammatory responses is negatively regulated through TLR2-dependent A20 expression.

  9. knockdown of A20 in tumor site inhibited tumor growth at least through inducing the apoptosis of MDSCs. A20 might be a potential target in anticancer therapy.

  10. MiR (zeige MLXIP Proteine)-221 directly targets A20, a master regulator of NF-kappaB (zeige NFKB1 Proteine) and MAPK (zeige MAPK1 Proteine) signaling, and thus represses inflammatory signaling. Restoration of A20 in macrophages abolished the stimulatory effect of miR (zeige MLXIP Proteine)-221 on production of proinflammatory cytokines.

Cow (Bovine) Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) Interaktionspartner

  1. Data show the characterization and deduced amino acid sequence analysis for A20 gene which expression increases in MDBK cells infected by BVDV-1. Also, regulatory regions for NF-kappaB (zeige NFKB1 Proteine) and Sp-1 (zeige SP1 Proteine) additionally to an ARE element for mRNA stability were detected

TNFAIP3 Protein Überblick

Protein Überblick

This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene.

Alternative names and synonyms associated with TNFAIP3

  • tumor necrosis factor, alpha-induced protein 3 (TNFAIP3)
  • tumor necrosis factor, alpha-induced protein 3 (tnfaip3)
  • tumor necrosis factor, alpha-induced protein 3 (Tnfaip3)
  • A20 Protein
  • MGC82339 Protein
  • OTUD7C Protein
  • TNFA1P2 Protein
  • TNFAIP3 Protein
  • Tnfip3 Protein

Bezeichner auf Proteinebene für TNFAIP3

tumor necrosis factor, alpha-induced protein 3 , OTU domain-containing protein 7C , TNF alpha-induced protein 3 , putative DNA-binding protein A20 , tumor necrosis factor alpha-induced protein 3 , tumor necrosis factor inducible protein A20 , zinc finger protein A20 , tumor necrosis factor induced protein 3

GENE ID SPEZIES
100073197 Equus caballus
421684 Gallus gallus
446998 Xenopus laevis
472136 Pan troglodytes
7128 Homo sapiens
21929 Mus musculus
683206 Rattus norvegicus
484006 Canis lupus familiaris
100622156 Sus scrofa
508105 Bos taurus
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