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Thyroglobulin Proteine (TG)

Bezeichnung:
Thyroglobulin Proteine (TG)
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Synonyme:
AITD3, cb717, cog, TG, Tgn
alle Proteine anzeigen Gen GeneID UniProt
TG 7038 P01266
TG 21819 O08710
Ratte TG TG 24826  

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Am meisten referenzierte Thyroglobulin Proteine

  1. Human Thyroglobulin Protein expressed in Human - ABIN934700 : Brorson, Reinholt: The intensity of immunogold labeling of deplasticized acrylic sections compared to deplasticized epoxy sections-Theoretical deductions and experimental data. in Micron (Oxford, England : 1993) 2008 (PubMed)

Weitere Proteine zu Thyroglobulin Interaktionspartnern

Zebrafish Thyroglobulin (TG) Interaktionspartner

Human Thyroglobulin (TG) Interaktionspartner

  1. Mutations in Thyroglobulin gene is associated with metastasis in Thyroid Cancer.

  2. Mutations in the genes for thyroglobulin and thyroid peroxidase (zeige TPO Proteine) cause thyroid dyshormonogenesis and autosomal-recessive intellectual disability

  3. Patients with low-and intermediate-risk differentiated thyroid carcinoma could be considered cured when their serum thyroglobulin levels were changed 6-12 months after thyroid ablation.

  4. The system is characterized by a very high sensitivity and specificity allowing the ex-vivo detection of sub ng/ml concentrations of human Thyroglobulin from needle washouts of fine-needle aspiration biopsies of thyroid nodule from different patients.

  5. High Thyroglobulin Levels are associated with recurrence in Thyroid Carcinoma.

  6. +49A/G and CT60 polymorphism of CTLA4 (zeige CTLA4 Proteine) and E33 (zeige NDUFAF3 Proteine) polymorphism of TG may be genetic risk factors for autoimmune hypothyroidism susceptibility.

  7. A prominent transient early increase in thyroglobulin levels was found in thyroid cancer patients post-radioiodine ablation.

  8. The mean and median of thyroglobulin were calculated in these subgroups. Tg concentrations were dependent on gender/

  9. Results from a Vietnamese family with goiter and hypothyroidism identified 2 novel mutations in thyroglobulin gene resulting in the abolition of the authentic splice donor sites.

  10. Data suggest serum TG level (low but measurable following stimulation with recombinant thyroid stimulating hormone or withdrawal of thyroid hormone (zeige PTH Proteine)) is predictive of incomplete response to surgery/radioiodine therapy in differentiated thyroid cancer.

Mouse (Murine) Thyroglobulin (TG) Interaktionspartner

  1. Final acquisition of secretory competence includes conformational maturation in the interval between linker and hinge segments of region I of thyroglobulin.

  2. The results showed that thyroglobulin message or protein is not expressed in placenta, decidua, or ovary in any stages of pregnancy.

  3. Findings demonstrate a novel aspect of murine and human thyroid autoimmunity, namely breaking B cell self-tolerance occurs first for Tg and subsequently for TPO (zeige THPO Proteine).

  4. These results indicate that Runx2 (zeige RUNX2 Proteine) deficiency in mice causes decreased Tg expression and a novel type of hypothyroidism.

  5. Five novel autoimmune thyroiditis-causing T cell epitopes of thyroglobulin (Tgn) have been delineated and mapped with an algorithm that predicts Tgn immunopathogenic peptides containing I-A(k)-binding motifs.

  6. iodotyrosyl formation in normal thyroglobulin confers pathogenic potential to certain peptides that may otherwise remain innocuous and undetectable by conventional mapping methods

  7. Tg could initiate glomerular injury by reproducing the actions of TGF-beta1 (zeige TGFB1 Proteine) in the mesangial cell.

Cow (Bovine) Thyroglobulin (TG) Interaktionspartner

  1. Solution studies, size exclusion chromatography, dynamic light scattering and analytical ultracentrifugation, demonstrated the size changes of thyroglobulin oligomers after nitric oxide treatment.

  2. The genetic effects of thyroglobulin and casein alpha s1 (zeige CSN1S1 Proteine) alpha in the body fat distribution of cattle are reported.

  3. Localization of thyrotropin receptor (zeige TSHR Proteine) and thyroglobulin in the bovine corpus luteum.

  4. Atrial natriuretic peptide (zeige NPPA Proteine) inhibits iodide uptake and thyroglobulin messenger ribonucleic acid expression in cultured bovine thyroid follicles.

  5. Markers at the thyroglobulin gene may be a useful predictor of marbling performance for producers raising Wagyu-based cattle; the SNP reported in the thyroglobulin gene was associated with marbling score in cattle with Wagyu inheritance

  6. Single nucleotide polymorphism of thyroglobulin gene is associated with fat deposition.

  7. we have demonstrated for the first time that thyroglobulin possesses proliferative effect on thyroid epithelial cells in addition to being the precursor of the thyroid hormones.

Thyroglobulin (TG) Protein Überblick

Protein Überblick

Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis.

Alternative names and synonyms associated with Thyroglobulin (TG)

  • thyroglobulin (TG)
  • thyroglobulin (tg)
  • thyroglobulin (Tg)
  • thyroglobulin (LOC100339135)
  • AITD3 Protein
  • cb717 Protein
  • cog Protein
  • TG Protein
  • Tgn Protein

Bezeichner auf Proteinebene für Thyroglobulin Proteine (TG)

thyroglobulin , thyroglobulin-like , congenital goiter , hereditary goitre

GENE ID SPEZIES
464407 Pan troglodytes
567631 Danio rerio
701526 Macaca mulatta
701756 Macaca mulatta
100405204 Callithrix jacchus
100434297 Pongo abelii
100582771 Nomascus leucogenys
100618718 Monodelphis domestica
7038 Homo sapiens
482047 Canis lupus familiaris
21819 Mus musculus
24826 Rattus norvegicus
280706 Bos taurus
101088550 Felis catus
100156471 Sus scrofa
100750237 Capra hircus
100721233 Cavia porcellus
100857838 Gallus gallus
101122868 Ovis aries
100339135 Oryctolagus cuniculus
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