Ligase I, DNA, ATP-Dependent ELISA Kits (LIG1)
Auf finden Sie aktuell 7 Ligase I, DNA, ATP-Dependent (LIG1) ELISA Kits von 5 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen LIG1 Antikörper (142) und LIG1 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 165 LIG1 Produkte verfügbar.
AL033288, ATLIG1, DNA ligase 1, lig1, LigI, T6D22.23, wu:fc54a11

LIG1 (LIG1) ELISA Kits nach Reaktivitäten

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Weitere ELISA Kits für LIG1 Interaktionspartner

Arabidopsis thaliana Ligase I, DNA, ATP-Dependent (LIG1) Interaktionspartner

  1. The AtLIG1 is an important component of the active DNA demethylation machinery.

  2. LIG1 is required for both single-nucleotide or long-patch base excision repair.

  3. In the study, we show that loss-of-function of the major DNA LIGASE I (AtLIG1) in Arabidopsis thaliana causes maternal effects in the endosperm, which is the seed tissue that nurtures embryo development.

  4. Nuclear or mitochondrial targeting of LIG1 is accomplished through an evolutionarily conserved translation initiation mechanism. [AtLIG1]

  5. DNA ligase 1 functions in both DNA replication and in repair of both ss and dsDNA strand breaks.

Human Ligase I, DNA, ATP-Dependent (LIG1) Interaktionspartner

  1. A histone H3K9-like mimic within LIG1 is methylated by G9a (zeige EHMT2 ELISA Kits) and GLP (zeige RCBTB1 ELISA Kits) and avidly binds UHRF1 (zeige UHRF1 ELISA Kits). Interaction with methylated LIG1 promotes the recruitment of UHRF1 (zeige UHRF1 ELISA Kits) to DNA replication sites and is required for DNA methylation (zeige HELLS ELISA Kits) maintenance.

  2. The rs156641 polymorphism of DNA ligase 1 (LIG1) was significantly associated with lung cancer risk, whereas no association was found between rs3730931/rs439132/rs20579 polymorphisms and lung cancer.

  3. Data suggest that DNA ligase I (LigI)-deficient 46BR.1G1 cells represent a model to investigate the biological effects of sub-lethal levels of DNA insults.

  4. The LIG1 CC genotype was associated with susceptibility to non-small cell lung cancer, and the AA genotype demonstrated increased radiosensitivity compared to the AC and CC genotypes.

  5. Ppolymorphisms in LIG1 affect its expression and may therefore change its function.

  6. there is no association between LIGI polymorphisms and cervical cancer risk. However, they may be playing an important role in modulating the risk of cervical adenocarcinoma in North Indian women

  7. DNA ligase I also interacts with replication factor C, the factor that loads the PCNA (zeige PCNA ELISA Kits) trimeric ring onto DNA.

  8. Data indicate that Ku70 (zeige XRCC6 ELISA Kits)/Ku80 (zeige XRCC5 ELISA Kits) facilitates the cooperative binding of multiple XRCC4 (zeige XRCC4 ELISA Kits)/Ligase IV (XL) and XLF (zeige NHEJ1 ELISA Kits) molecules to DNA.

  9. Single nucleotide polymorphisms in LIG1 are associated with myelodysplastic syndromes.

  10. phosphorylation of serine 51 on hLigI plays a critical role in regulating the interaction between hLigI and RFC (zeige RFC1 ELISA Kits), which is required for efficient DNA replication and repair.

Mouse (Murine) Ligase I, DNA, ATP-Dependent (LIG1) Interaktionspartner

  1. Increased presynaptic glutamate (zeige GRIN1 ELISA Kits) release is a key early event resulting from Lgi1 (zeige LGI1 ELISA Kits)-deficiency, which likely contributes to epileptogenesis.

  2. Lig1 (zeige Lrig1 ELISA Kits) is not absolutely required for cellular DNA replication and repair in Lig1 (zeige Lrig1 ELISA Kits)-null cell line.

  3. LigI has a highly specific role in CTG repeat maintenance in the maternal germline, involved in mediating CTG expansions and in the avoidance of maternal CTG contractions.

  4. DNA ligase I null mouse cells show normal DNA repair activity but altered DNA replication and reduced genome stability.

LIG1 Antigen-Profil

Beschreibung des Gens

LIG1 encodes DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in LIG1 that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents.

Alternative names and synonyms associated with LIG1

  • ligase I, DNA, ATP-dependent (LIG1) Elisa Kit
  • DNA ligase 1 (PB000674.02.0) Elisa Kit
  • DNA ligase 1 (PTRG_06243) Elisa Kit
  • DNA ligase 1 (PKH_140260) Elisa Kit
  • DNA ligase 1 (LIG1) Elisa Kit
  • ligase I, DNA, ATP-dependent (lig1) Elisa Kit
  • ligase I, DNA, ATP-dependent (Lig1) Elisa Kit
  • Protein LIG-1 (lig-1) Elisa Kit
  • si:dkeyp-35b8.5 (si:dkeyp-35b8.5) Elisa Kit
  • AL033288 Elisa Kit
  • ATLIG1 Elisa Kit
  • DNA ligase 1 Elisa Kit
  • lig1 Elisa Kit
  • LigI Elisa Kit
  • T6D22.23 Elisa Kit
  • wu:fc54a11 Elisa Kit

Bezeichner auf Proteinebene für LIG1

DNA ligase 1 , polydeoxyribonucleotide synthase [ATP] 1 , DNA ligase (ATP) 1 , DNA ligase I , LIG1, ligase I, DNA, ATP-dependent

100053186 Equus caballus
3425646 Plasmodium berghei ANKA
6344500 Pyrenophora tritici-repentis Pt-1C-BFP
7323359 Plasmodium knowlesi strain H
837333 Arabidopsis thaliana
3978 Homo sapiens
100124507 Bos taurus
397978 Xenopus laevis
100686967 Canis lupus familiaris
16881 Mus musculus
81513 Rattus norvegicus
100520434 Sus scrofa
179502 Caenorhabditis elegans
556995 Danio rerio
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