anti-LIG1 (LIG1) Antikörper

anti-Ligase I, DNA, ATP-Dependent Antikörper (LIG1)
Auf finden Sie aktuell 142 Ligase I, DNA, ATP-Dependent (LIG1) Antikörper von 19 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen LIG1 Kits (7) und LIG1 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 165 LIG1 Produkte verfügbar.
AL033288, ATLIG1, DNA ligase 1, lig1, LigI, T6D22.23, wu:fc54a11

Meistgesuchte Reaktivitäten zu anti-LIG1 (LIG1) Antikörper

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anti-Human LIG1 Antikörper:

anti-Mouse (Murine) LIG1 Antikörper:

anti-Rat (Rattus) LIG1 Antikörper:

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Am meisten referenzierte anti-LIG1 Antikörper

  1. Human Monoclonal LIG1 Primary Antibody für ICC, IF - ABIN4305490 : Wang, Lindsey-Boltz, Sancar, Bambara: Mechanism of stimulation of human DNA ligase I by the Rad9-rad1-Hus1 checkpoint complex. in The Journal of biological chemistry 2006 (PubMed)
    Zeige alle 23 Referenzen für 4305490

  2. Human Polyclonal LIG1 Primary Antibody für EIA, WB - ABIN951930 : Arora, Lindgren, Basu, Nagaraj, Gross, Weisdorf, Thyagarajan: Polymorphisms in the base excision repair pathway and graft-versus-host disease. in Leukemia 2010 (PubMed)
    Zeige alle 4 Referenzen für 951930

  3. Cow (Bovine) Monoclonal LIG1 Primary Antibody für ELISA, IHC - ABIN4305494 : Liang, Deng, Nguyen, Zhao, Maulion, Shao, Tischfield: Human DNA ligases I and III, but not ligase IV, are required for microhomology-mediated end joining of DNA double-strand breaks. in Nucleic acids research 2008 (PubMed)

  4. Human Polyclonal LIG1 Primary Antibody für ELISA, WB - ABIN4305493 : Ferrari, Rossi, Arosio, Vindigni, Biamonti, Montecucco: Cell cycle-dependent phosphorylation of human DNA ligase I at the cyclin-dependent kinase sites. in The Journal of biological chemistry 2003 (PubMed)

  5. Human Polyclonal LIG1 Primary Antibody für WB - ABIN658750 : Guillem, Cervantes, Martínez, Alvarez-Larrán, Collado, Camós, Sureda, Maffioli, Marugán, Hernández-Boluda: XPC genetic polymorphisms correlate with the response to imatinib treatment in patients with chronic phase chronic myeloid leukemia. in American journal of hematology 2010 (PubMed)

Weitere Antikörper gegen LIG1 Interaktionspartner

Arabidopsis thaliana Ligase I, DNA, ATP-Dependent (LIG1) Interaktionspartner

  1. The AtLIG1 is an important component of the active DNA demethylation machinery.

  2. LIG1 is required for both single-nucleotide or long-patch base excision repair.

  3. In the study, we show that loss-of-function of the major DNA LIGASE I (AtLIG1) in Arabidopsis thaliana causes maternal effects in the endosperm, which is the seed tissue that nurtures embryo development.

  4. Nuclear or mitochondrial targeting of LIG1 is accomplished through an evolutionarily conserved translation initiation mechanism. [AtLIG1]

  5. DNA ligase 1 functions in both DNA replication and in repair of both ss and dsDNA strand breaks.

Human Ligase I, DNA, ATP-Dependent (LIG1) Interaktionspartner

  1. A histone H3K9-like mimic within LIG1 is methylated by G9a (zeige EHMT2 Antikörper) and GLP (zeige RCBTB1 Antikörper) and avidly binds UHRF1 (zeige UHRF1 Antikörper). Interaction with methylated LIG1 promotes the recruitment of UHRF1 (zeige UHRF1 Antikörper) to DNA replication sites and is required for DNA methylation (zeige HELLS Antikörper) maintenance.

  2. The rs156641 polymorphism of DNA ligase 1 (LIG1) was significantly associated with lung cancer risk, whereas no association was found between rs3730931/rs439132/rs20579 polymorphisms and lung cancer.

  3. Data suggest that DNA ligase I (LigI)-deficient 46BR.1G1 cells represent a model to investigate the biological effects of sub-lethal levels of DNA insults.

  4. The LIG1 CC genotype was associated with susceptibility to non-small cell lung cancer, and the AA genotype demonstrated increased radiosensitivity compared to the AC and CC genotypes.

  5. Ppolymorphisms in LIG1 affect its expression and may therefore change its function.

  6. there is no association between LIGI polymorphisms and cervical cancer risk. However, they may be playing an important role in modulating the risk of cervical adenocarcinoma in North Indian women

  7. DNA ligase I also interacts with replication factor C, the factor that loads the PCNA (zeige PCNA Antikörper) trimeric ring onto DNA.

  8. Data indicate that Ku70 (zeige XRCC6 Antikörper)/Ku80 (zeige XRCC5 Antikörper) facilitates the cooperative binding of multiple XRCC4 (zeige XRCC4 Antikörper)/Ligase IV (XL) and XLF (zeige NHEJ1 Antikörper) molecules to DNA.

  9. Single nucleotide polymorphisms in LIG1 are associated with myelodysplastic syndromes.

  10. phosphorylation of serine 51 on hLigI plays a critical role in regulating the interaction between hLigI and RFC (zeige RFC1 Antikörper), which is required for efficient DNA replication and repair.

Mouse (Murine) Ligase I, DNA, ATP-Dependent (LIG1) Interaktionspartner

  1. Increased presynaptic glutamate (zeige GRIN1 Antikörper) release is a key early event resulting from Lgi1 (zeige LGI1 Antikörper)-deficiency, which likely contributes to epileptogenesis.

  2. Lig1 (zeige Lrig1 Antikörper) is not absolutely required for cellular DNA replication and repair in Lig1 (zeige Lrig1 Antikörper)-null cell line.

  3. LigI has a highly specific role in CTG repeat maintenance in the maternal germline, involved in mediating CTG expansions and in the avoidance of maternal CTG contractions.

  4. DNA ligase I null mouse cells show normal DNA repair activity but altered DNA replication and reduced genome stability.

LIG1 Antigen-Profil

Beschreibung des Gens

LIG1 encodes DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in LIG1 that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents.

Alternative names and synonyms associated with LIG1

  • ligase I, DNA, ATP-dependent (LIG1) Antikörper
  • DNA ligase 1 (PB000674.02.0) Antikörper
  • DNA ligase 1 (PTRG_06243) Antikörper
  • DNA ligase 1 (PKH_140260) Antikörper
  • DNA ligase 1 (LIG1) Antikörper
  • ligase I, DNA, ATP-dependent (lig1) Antikörper
  • ligase I, DNA, ATP-dependent (Lig1) Antikörper
  • Protein LIG-1 (lig-1) Antikörper
  • si:dkeyp-35b8.5 (si:dkeyp-35b8.5) Antikörper
  • AL033288 Antikörper
  • ATLIG1 Antikörper
  • DNA ligase 1 Antikörper
  • lig1 Antikörper
  • LigI Antikörper
  • T6D22.23 Antikörper
  • wu:fc54a11 Antikörper

Bezeichner auf Proteinebene für LIG1

DNA ligase 1 , polydeoxyribonucleotide synthase [ATP] 1 , DNA ligase (ATP) 1 , DNA ligase I , LIG1, ligase I, DNA, ATP-dependent

100053186 Equus caballus
3425646 Plasmodium berghei ANKA
6344500 Pyrenophora tritici-repentis Pt-1C-BFP
7323359 Plasmodium knowlesi strain H
837333 Arabidopsis thaliana
3978 Homo sapiens
100124507 Bos taurus
397978 Xenopus laevis
100686967 Canis lupus familiaris
16881 Mus musculus
81513 Rattus norvegicus
100520434 Sus scrofa
179502 Caenorhabditis elegans
556995 Danio rerio
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