Phosphotylinosital 3 Kinase Proteine (PI3K)

Phosphotylinosital 3 Kinase Proteine (PI3K)
Auf finden Sie aktuell 4 Phosphotylinosital 3 Kinase (PI3K) Proteine von 3 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Phosphotylinosital 3 Kinase Kits (21) und Phosphotylinosital 3 Kinase Antikörper (3) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 29 Phosphotylinosital 3 Kinase Produkte verfügbar.
AA414921, C530050K14, p50alpha, p55alpha, p85alpha, PI3K
alle Proteine anzeigen Gen GeneID UniProt
Maus PI3K PI3K 18708 P26450

Weitere Synonyme anzeigen

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Weitere Proteine zu Phosphotylinosital 3 Kinase Interaktionspartnern

Mouse (Murine) Phosphotylinosital 3 Kinase (PI3K) Interaktionspartner

  1. insulin (zeige INS Proteine) and aPC (zeige APC Proteine) converge on a common spliced-X-box binding protein-1 (zeige XBP1 Proteine) (sXBP1) signaling pathway to maintain endoplasmic reticulum (ER) homeostasis.

  2. Data demonstrated a novel role of Pik3r1 that was independent of the regulatory function of phosphoinositide 3-kinase in mediating the metabolic action of glucocorticoids. Glucocorticoids increased hormone sensitive lipase phosphorylation, but not Plin1 phosphorylation, in adipose tissue-specific Pik3r1-null (AKO) mice.

  3. Collectively, these findings showed that SA suppressed mammary gland development of pubertal mice, which was coincident with the SA-inhibited HC11 proliferation, and was associated with inhibition of PI3K/Akt signaling pathway through activation of GPR120.

  4. suggest that small-bowel resection reduces p85alpha and TP53 (zeige TP53 Proteine), which increases survivin (zeige BIRC5 Proteine) and intestinal epithelial cell expansion during therapeutic adaptation in patients with short bowel syndrome

  5. These results indicate that there is a tissue-specific regulation of IGF-1 (zeige IGF1 Proteine)/PI3K/Akt (zeige AKT1 Proteine) during normal aging and upon dietary restriction to help maintain the metabolic status of these tissues at those phases of animal's lifespan.

  6. Uncarboxylated osteocalcin (zeige BGLAP Proteine) inhibits high glucose-induced reactive oxygen species production and stimulates osteoblastic differentiation by inhibiting the activation of PI3K/Akt (zeige AKT1 Proteine) in MC3T3-E1 cells.

  7. miR-130a plays a critical role in attenuation of cardiac dysfunction and remodeling after myocardial infarction. The mechanisms involve activation of PI3K/Akt signaling via suppression of PTEN expression.

  8. PI3K/AKT (zeige AKT1 Proteine) pathway was partially involved in the modulation of the release HMGB-1 (zeige HMGB1 Proteine) from reactive astrocytes.

  9. These data demonstrate the ability of this heterozygous mutation to alter PI3K activity in vivo and the central role of PI3K in insulin (zeige INS Proteine)/growth factor action, adipocyte function, and glucose metabolism.

  10. These results suggested that cordycein is a highly selective treatment to induce MA-10 cells apoptosis via p38 (zeige CRK Proteine) MAPKs signaling.

Phosphotylinosital 3 Kinase (PI3K) Protein Überblick

Protein Überblick

Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling (By similarity).

Alternative names and synonyms associated with Phosphotylinosital 3 Kinase (PI3K)

  • phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) (Pik3r1)
  • AA414921 Protein
  • C530050K14 Protein
  • p50alpha Protein
  • p55alpha Protein
  • p85alpha Protein
  • PI3K Protein

Bezeichner auf Proteinebene für PI3K

PI3-kinase regulatory subunit alpha , PI3-kinase subunit p85-alpha , PI3K regulatory subunit alpha , phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha , phosphatidylinositol 3-kinase regulatory subunit alpha , ptdIns-3-kinase regulatory subunit alpha , ptdIns-3-kinase regulatory subunit p85-alpha

18708 Mus musculus
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