IL17A Proteine (IL17A)

Interleukin 17A Proteine (IL17A)
Auf finden Sie aktuell 110 Interleukin 17A (IL17A) Proteine von 18 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen IL17A Antikörper (512) und IL17A Kits (114) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 752 IL17A Produkte verfügbar.
ChIL-17, CTLA-8, Ctla8, IL-17, IL-17A, IL-17F, IL17, IL17A
alle Proteine anzeigen Gen GeneID UniProt
IL17A 25465  
IL17A 3605 Q16552
IL17A 16171 Q62386

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Am meisten referenzierte IL17A Proteine

  1. Mouse (Murine) IL17A Protein expressed in Escherichia coli (E. coli) - ABIN2667468 : Ouyang, Kolls, Zheng: The biological functions of T helper 17 cell effector cytokines in inflammation. in Immunity 2008 (PubMed)
    Zeige alle 10 Referenzen für 2667468

  2. Human IL17A Protein expressed in Escherichia coli (E. coli) - ABIN2667466 : Yu, Gaffen: Interleukin-17: a novel inflammatory cytokine that bridges innate and adaptive immunity. in Frontiers in bioscience : a journal and virtual library 2007 (PubMed)
    Zeige alle 7 Referenzen für 2667466

  3. Human IL17A Protein expressed in Escherichia coli (E. coli) - ABIN413453 : Bérubé, Roussel, Nattagh, Rousseau et al.: Loss of cystic fibrosis transmembrane conductance regulator function enhances activation of p38 and ERK MAPKs, increasing interleukin-6 synthesis in airway epithelial cells exposed to Pseudomonas ... in The Journal of biological chemistry 2010 (PubMed)
    Zeige alle 3 Referenzen für 413453

  4. Rat (Rattus) IL17A Protein expressed in Escherichia coli (E. coli) - ABIN413456 : Arif, Moore, Marks, Bouckenooghe, Dayan, Planas, Vives-Pi, Powrie, Tree, Marchetti, Huang, Gurzov, Pujol-Borrell, Eizirik, Peakman: Peripheral and islet interleukin-17 pathway activation characterizes human autoimmune diabetes and promotes cytokine-mediated β-cell death. in Diabetes 2011 (PubMed)

Weitere Proteine zu IL17A Interaktionspartnern

Rhesus Monkey Interleukin 17A (IL17A) Interaktionspartner

  1. Data indicate that IL-17/22-producing cells play an important role in maintenance of intestinal mucosa in gluten-sensitive primates.

Human Interleukin 17A (IL17A) Interaktionspartner

  1. High IL17 expression is associated with gastric cancer.

  2. Serum Levels of IL-17A and IL-23 (zeige IL23A Proteine) Are Associated with Decreased Vitamin D3 and Increased Pain in Osteoarthritis

  3. exogenous IL-17A is stored in intracellular granules and can subsequently be released in a bioactive form

  4. the results of this study suggest that changed patterns of expression of the IL-17 cytokine family ligands and receptors might be associated with infiltration of inflammatory cells and structural cells (CD90 (zeige THY1 Proteine)+ fibroblasts and CD31 (zeige HBA1 Proteine)+ blood vessels), which might also contribute to occurrence and development in bladder cancer

  5. mild psoriasis was characterized by higher numbers of T cells in skin lesions, higher IL-17A expression, and stronger expression of the core psoriasis transcriptome.

  6. The current study emphasizes the lack of association of IL23R (zeige IL23R Proteine) and IL17 polymorphisms with rheumatoid arthritis susceptibility in the Algerian population. However, the data showed the relationship between IL23R (zeige IL23R Proteine) and IL17A polymorphisms and the production of the different RF isotypes in rheumatoid arthritis patients

  7. High levels of IL-17 is associated with lyme disease.

  8. The presence of IL-17 in the synovial fluid identifies a substantial subset of primary end-stage osteoarthritis patients with distinct biological and clinical features. Stratification of patients on the basis of IL-17 may identify those responsive to therapeutic targeting.

  9. observed inverse relationship between the circulating levels of IFN-gamma (zeige IFNG Proteine) and IL-17 together with the reduction in the levels of memory-like CD4 (zeige CD4 Proteine)+ T cells expressing IL-17 in children with SMA (zeige SMN1 Proteine) may suggest possible relocation of these cells in the deeper tissues for their pathological effect

  10. Low levels of miR (zeige MLXIP Proteine)-635 and miR (zeige MLXIP Proteine)-578 expression were associated with high expression of IL-17A, suggesting that IL-17A and its targeting miRNAs contribute to the pathogenesis of OLP.

Mouse (Murine) Interleukin 17A (IL17A) Interaktionspartner

  1. these results identify a distinct pathway in which IL-17 production by splenic LSK (zeige LCK Proteine)- cells supports their differentiation into B cells in response to acute Plasmodium infection

  2. this study shows that an ocular commensal protects against corneal infection by driving an IL-17a response from mucosal TCR gamma delta T Cells

  3. IL-17 A showed two distinct peaks of expression in the ischemic hemisphere: the first occurring within 3 days and the second on day 28 after stroke.

  4. this study shows that that OX40 (zeige TNFRSF4 Proteine) stimulation inhibits IL-17 and reduces experimental autoimmune encephalomyelitis

  5. this study shows that anti-IL-17 monoclonal antibodies treatment protects against allergic rhinitis

  6. our results demonstrated that IL-17A was involved in intracerebral haemorrhage-induced microglial activation and neuroinflammation.

  7. these findings demonstrate a new role of IL-17 in promoting autoimmunity in part through directly enhancing B cell proliferation, differentiation, and plasma cell generation.

  8. The suppression of nasal inflammation due of IL-17A deficiency in allergic rhinitis is partly responsible for the regulation of CCL7 (zeige CCL7 Proteine) secretion and eosinophil infiltration, which may be regulated via the CCL7 (zeige CCL7 Proteine)/CCR3 (zeige CCR3 Proteine) pathway.

  9. IL-17A blockade led to an increase in the frequency of IL-17A-producing T-helper cell type 17 cells and gammadelta T cells in lung allografts, suggesting that IL-17A is a negative regulator of these T cells.

  10. this study shows that IL-17A contributes to asthma pathophysiology by increasing the capacity of IL-13 (zeige IL13 Proteine) to activate intracellular signaling pathways, such as STAT6 (zeige STAT6 Proteine) activation

Pig (Porcine) Interleukin 17A (IL17A) Interaktionspartner

  1. At week 15, skin cell infiltrates from pigs with crusted scabies had significantly higher CD8 (zeige CD8A Proteine)+ T cell, gammadelta T cell and IL-17+ cell numbers than those with ordinary scabies. Peripheral IL-17 levels were not increased, suggesting that localized skin IL-17-secreting T cells may play a critical role in the pathogenesis of crusted scabies development.

  2. Alterations in the IL-17 regulated pathway of porcine colon in response to dietary supplementation with seaweeds and yeast are reported.

  3. conclude that only two subpopulations of porcine WBCs are sources of IL-17 after non-specific stimulation: CD3 (zeige CD3 Proteine)(+)CD4 (zeige CD4 Proteine)(+) and CD3 (zeige CD3 Proteine)(+)gammadeltaTCR(+).

  4. Cloning and expression of interleukin-17.

Cow (Bovine) Interleukin 17A (IL17A) Interaktionspartner

  1. calves, like humans, mount a robust IL-17 response during respiratory syncytial virus infection.

  2. Data show that CD4 (zeige CD4 Proteine)(+) and WC1(+) gammadelta T-cells were induced to produce IL-17 termed Th17 and gammadelta17 cells.

  3. IL-17A was shown to be upregulated, supporting its investigation as a potential biomarker of bTB.

  4. IL-17A and IL-17F (zeige IL17F Proteine) have a potential to modulate the mammary gland immune response to mastitis-causing pathogens.

  5. The results of this study provide evidence of the role of IL-17 in the immunopathology of tuberculosis and support the use of IL-17 as a potential biomarker with predictive value of prognosis in bTB.

Horse (Equine) Interleukin 17A (IL17A) Interaktionspartner

  1. Data show increased interleukin 17 (IL-17) staining intensity in mediastinal lymph node from chronic recurrent airway obstruction (RAO (zeige AOC2 Proteine)) horses.

  2. cloning and characterization of interleukin-17 expressed gene sequence from mRNA obtained from intestinal tissue and interleukin-23 expressed gene sequence from mRNA obtained from peripheral blood mononuclear cells

  3. This study examined effects of in vitro exposure to solutions of hay (zeige GTF2H5 Proteine) dust, lipopolysaccharides, or beta-glucan on cytokine expression in pulmonary mononuclear cells isolated from healthy horses and horses with recurrent airway obstruction.

Guinea Pig Interleukin 17A (IL17A) Interaktionspartner

  1. molecular cloning and expression of recombinant IL-17A; homology modeling revealed that the three-dimensional structure resembles that of human IL-17A. The secondary structure predicted showed the presence of one extra helix in the N-terminal region.

Rabbit Interleukin 17A (IL17A) Interaktionspartner

  1. one of the interaction sites between IL17A and its receptor IL17RA (zeige IL17RA Proteine)

IL17A Protein Überblick

Protein Überblick

The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

Alternative names and synonyms associated with IL17A

  • interleukin 17A (Il17a)
  • interleukin 17A (IL17A)
  • interleukin 17A-like (LOC100339322)
  • interleukin 17F (IL17F)
  • ChIL-17 Protein
  • CTLA-8 Protein
  • Ctla8 Protein
  • IL-17 Protein
  • IL-17A Protein
  • IL-17F Protein
  • IL17 Protein
  • IL17A Protein

Bezeichner auf Proteinebene für Interleukin 17A Proteine (IL17A)

interleukin 17A , Interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8) , CTLA-8 , cytotoxic T-lymphocyte-associated antigen 8 , cytotoxic T-lymphocyte-associated protein 8 , interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8) , interleukin-17A , IL-17 , IL-17A , interleukin-17 , interleukin 17

25465 Rattus norvegicus
472029 Pan troglodytes
708123 Macaca mulatta
3605 Homo sapiens
16171 Mus musculus
301289 Rattus norvegicus
449530 Sus scrofa
282863 Bos taurus
100034142 Equus caballus
100735572 Cavia porcellus
100860877 Capra hircus
481837 Canis lupus familiaris
101103931 Ovis aries
100339322 Oryctolagus cuniculus
395111 Gallus gallus
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