anti-Aurora Kinase B (AURKB) Antikörper

Bezeichnung:
anti-Aurora Kinase B Antikörper (AURKB)
Auf www.antikoerper-online.de finden Sie aktuell 298 Aurora Kinase B (AURKB) Antikörper von 28 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Aurora Kinase B Proteine (21) und Aurora Kinase B Kits (11) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 342 Aurora Kinase B Produkte verfügbar.
Synonyme:
Aik2, AIM-1, Aim1, AIRK2, AL022959, ARK-2, Ark2, Aur B, aurB, aurkb, aurkb-sv1, aurkb-sv2, Aurora-B, aurora B, CG6620, CHUNP6896, DmAIRK2, DmAurB, DmAuroraB, Dmel\\CG6620, fa09g06, Ial, IAL1, IKK2, IPL1, PPP1R48, STK-1, Stk5, Stk12, stka, wu:fa09g06, XAIRK2

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anti-Human Aurora Kinase B Antikörper:

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Am meisten referenzierte anti-Aurora Kinase B Antikörper

  1. Human Polyclonal Aurora Kinase B Primary Antibody für ICC, IF - ABIN151760 : Adams, Eckley, Vagnarelli, Wheatley, Gerloff, Mackay, Svingen, Kaufmann, Earnshaw: Human INCENP colocalizes with the Aurora-B/AIRK2 kinase on chromosomes and is overexpressed in tumour cells. in Chromosoma 2001 (PubMed)
    Zeige alle 10 Referenzen für 151760

  2. Human Polyclonal Aurora Kinase B Primary Antibody für EIA, WB - ABIN117978 : Honda, Asato, Tanaka, Endo, Nishimura, Ito: Vidian nerve schwannoma with middle cranial fossa extension resected via a maxillary swing approach. in Head & neck 2008 (PubMed)
    Zeige alle 9 Referenzen für 117978

  3. Human Monoclonal Aurora Kinase B Primary Antibody für IF, WB - ABIN968357 : Chen, Jin, Tahir, Zhang, Liu, Sarthy, McGonigal, Liu, Rosenberg, Ng: Survivin enhances Aurora-B kinase activity and localizes Aurora-B in human cells. in The Journal of biological chemistry 2002 (PubMed)
    Zeige alle 5 Referenzen für 968357

  4. Human Polyclonal Aurora Kinase B Primary Antibody für ICC, IF - ABIN152999 : Qi, Tang, Yu: Phosphorylation- and polo-box-dependent binding of Plk1 to Bub1 is required for the kinetochore localization of Plk1. in Molecular biology of the cell 2006 (PubMed)
    Zeige alle 3 Referenzen für 152999

  5. Human Polyclonal Aurora Kinase B Primary Antibody für ELISA, WB - ABIN1043878 : Wheatley, Henzing, Dodson, Khaled, Earnshaw: Aurora-B phosphorylation in vitro identifies a residue of survivin that is essential for its localization and binding to inner centromere protein (INCENP) in vivo. in The Journal of biological chemistry 2004 (PubMed)

  6. Human Polyclonal Aurora Kinase B Primary Antibody für ELISA, WB - ABIN129612 : Mackay, Makise, Ullman: Defects in nuclear pore assembly lead to activation of an Aurora B-mediated abscission checkpoint. in The Journal of cell biology 2010 (PubMed)

  7. Human Polyclonal Aurora Kinase B Primary Antibody für ICC, IF - ABIN408113 : Togashi, Shirakawa, Orime, Kaji, Sakamoto, Tajima, Inoue, Nakamura, Tochino, Goshima, Shimomura, Terauchi: β-Cell proliferation after a partial pancreatectomy is independent of IRS-2 in mice. in Endocrinology 2014 (PubMed)

Weitere Antikörper gegen Aurora Kinase B Interaktionspartner

Fruit Fly (Drosophila melanogaster) Aurora Kinase B (AURKB) Interaktionspartner

  1. Aurora A (zeige AURKA Antikörper) and B kinases directly phosphorylate Lgl to promote its mitotic relocalization.

  2. Regulation of Polo (zeige PLK1 Antikörper) by Aurora B and Map205 is required for cytokinesis.

  3. We propose that mutual inhibitions between Aurora B a (zeige CDK1 Antikörper)nd Cyclin B regulate the duration of abscission and thereby the number of sister cells in each cyst.

  4. Aurora B kinase activity is not required during contractile ring ingression, providing insight into the mechanism of cytokinesis.

  5. Aurora B interacts with and requires the Cdc37 (zeige CDC37 Antikörper)/Hsp90 (zeige HSP90 Antikörper) complex for its stability.

  6. INCENP (zeige INCENP Antikörper) binds to the cohesion protector protein (zeige PRDX2 Antikörper) MEI-S332, which is also an excellent in vitro substrate for Aurora B kinase.

Human Aurora Kinase B (AURKB) Interaktionspartner

  1. Aurora B kinase interacts with and phosphorylates Sgo1 (zeige SGOL1 Antikörper). Aurora B-mediated phosphorylation of Sgo1 (zeige SGOL1 Antikörper) regulates the distribution of Sgo1 (zeige SGOL1 Antikörper) between centromeres and chromosome arms.

  2. AURKC (zeige AURKC Antikörper) rs758099 TT and (CC + CT) genotypes were positively associated with increased intestinal type gastric cancer (GC)risk, but not with an increased diffuse type GC risk. Based on these results, we can conclude that AURKA (zeige AURKA Antikörper) rs1047972 and AURKC (zeige AURKC Antikörper) rs758099 polymorphisms could affect the risk of GC development.

  3. Aurora-C (zeige AURKC Antikörper) interactions with members of the Chromosome Passenger Complex (CPC), Survivin (zeige BIRC5 Antikörper) and Inner Centromere Protein (INCENP (zeige INCENP Antikörper)) in reference to known Aurora-B interactions to understand the functional significance of Aurora-C (zeige AURKC Antikörper) overexpression in human cancer cells, is reported.

  4. Aurora kinase (zeige AURKA Antikörper) inhibitor danusertib negatively regulated AURKB/p70S6K (zeige RPS6KB1 Antikörper)/RPL15 (zeige RPL15 Antikörper) axis with the involvement of PI3K (zeige PIK3CA Antikörper)/Akt (zeige AKT1 Antikörper)/mTOR (zeige FRAP1 Antikörper), AMPK (zeige PRKAA1 Antikörper), and p38 MAPK (zeige MAPK14 Antikörper) signaling pathways, leading to the induction of apoptosis and autophagy in human leukemia cells.

  5. The kinase activity of Aurora B on serine 31 of histone H3.3 (zeige H3F3A Antikörper) was biochemically confirmed with nucleosomal substrates in vitro.

  6. in addition to its role in checkpoint signaling, MAD2 (zeige MAD2L1 Antikörper) ensures chromosome stability through the regulation of AURORA B.

  7. Ska promotes Aurora B activity to limit its own microtubule and kinetochore association.

  8. partial co-localization of AKT3 (zeige AKT3 Antikörper) with AURKB was observed during anaphase. Overall, this study suggests that AKT3 (zeige AKT3 Antikörper) could repress the antiproliferative effects of AURKi, with a novel activity particularly suppressing the aneuploidy induction.

  9. Our study mechanistically explains a p53 (zeige TP53 Antikörper)-independent mode of action of a chemical Aurora B inhibitor and suggests a potential triggering of antitumoral immune responses, following polyploidization of tumor cells, which might constrain recovery of aneuploid tumor cells.

  10. Our data demonstrate that the cytokinetic proteins epithelial cell transforming 2 and Aurora kinase B (AurkB) are localized to stress granules in human astrocytoma cells

Mouse (Murine) Aurora Kinase B (AURKB) Interaktionspartner

  1. Aurkb phosphorylates Oct4 (zeige POU5F1 Antikörper)(S229) during G2/M phase, leading to the dissociation of Oct4 (zeige POU5F1 Antikörper) from chromatin, whereas PP1 (zeige PPP1CC Antikörper) binds Oct4 (zeige POU5F1 Antikörper) and dephosphorylates Oct4 (zeige POU5F1 Antikörper)(S229) during M/G1 transition, which resets Oct4 (zeige POU5F1 Antikörper)-driven transcription for pluripotency and the cell cycle.

  2. Overexpression of Aurora B (zeige AURKC Antikörper) also results in a reduced DNA damage response and decreased levels of the p53 (zeige TP53 Antikörper) target p21(Cip1 (zeige CDKN1A Antikörper)) in vitro and in vivo.

  3. Chromsome stability is on of the tumor-suppressive functions of ARF (zeige CDKN2A Antikörper) as well as regulation of Aurora B (zeige AURKC Antikörper) expression in tumors.

  4. Using this mutant we show for the first time that AURKC has functions that do not overlap with AURKB. These functions include regulating localized CPC activity and regulating chromosome alignment and K-MT attachments at metaphase of meiosis I (Met I).

  5. reduced accumulation of Aurora B (zeige AURKC Antikörper) at the inner centromere region in cells lacking Pds5B (zeige PDS5B Antikörper) impairs its error correction function, promoting chromosome mis (zeige AMH Antikörper)-segregation and aneuploidy

  6. Aurora B (zeige AURKC Antikörper) and Ring1B (zeige RNF2 Antikörper) co-occupy active promoters in resting lymphocytes.

  7. FBXL2 (zeige FBXL2 Antikörper) mediates Aurora B (zeige AURKC Antikörper) ubiquitination and degradation within the midbody, which is sufficient to induce mitotic arrest and apoptosis.

  8. Inhibitions of Aurora B (zeige AURKC Antikörper) and Cyclin-dependent kinase 1 (zeige CDK1 Antikörper) activity in vertebrate cells also have opposite effects on the timing of abscission.

  9. Aurora B (zeige AURKC Antikörper) represses p21(Cip1 (zeige CDKN1A Antikörper)), preventing delayed DNA replication, Cdk (zeige CDK4 Antikörper) inhibition and premature mitotic exit.

  10. Calmodulin (zeige Calm2 Antikörper) protects Aurora B (zeige AURKC Antikörper) on the midbody to regulate the fidelity of cytokinesis.

Cow (Bovine) Aurora Kinase B (AURKB) Interaktionspartner

  1. Alterations in PGRMC1 (zeige PGRMC1 Antikörper) and/or AURKB localization account in part for the increased aneuploidy and low development competence of oocytes from ovaries with reduced antral follicle counts.

  2. AURKB associated with metaphase chromosomes.

Zebrafish Aurora Kinase B (AURKB) Interaktionspartner

  1. Aurora B kinase is essential for furrow induction and maturation in the zebrafish embryo.

Aurora Kinase B (AURKB) Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 19 and 20. These kinases participate in the regulation of segregation of chromosomes during mitosis and meiosis through association with microtubules. A pseudogene of this gene is located on chromosome 8. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Aurora Kinase B (AURKB)

  • IplI-aurora-like kinase (ial) Antikörper
  • aurora kinase B (aurkb) Antikörper
  • aurora kinase B (AURKB) Antikörper
  • aurora kinase B (Aurkb) Antikörper
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (Ikbkb) Antikörper
  • Aik2 Antikörper
  • AIM-1 Antikörper
  • Aim1 Antikörper
  • AIRK2 Antikörper
  • AL022959 Antikörper
  • ARK-2 Antikörper
  • Ark2 Antikörper
  • Aur B Antikörper
  • aurB Antikörper
  • aurkb Antikörper
  • aurkb-sv1 Antikörper
  • aurkb-sv2 Antikörper
  • Aurora-B Antikörper
  • aurora B Antikörper
  • CG6620 Antikörper
  • CHUNP6896 Antikörper
  • DmAIRK2 Antikörper
  • DmAurB Antikörper
  • DmAuroraB Antikörper
  • Dmel\\CG6620 Antikörper
  • fa09g06 Antikörper
  • Ial Antikörper
  • IAL1 Antikörper
  • IKK2 Antikörper
  • IPL1 Antikörper
  • PPP1R48 Antikörper
  • STK-1 Antikörper
  • Stk5 Antikörper
  • Stk12 Antikörper
  • stka Antikörper
  • wu:fa09g06 Antikörper
  • XAIRK2 Antikörper

Bezeichner auf Proteinebene für AURKB

AURORA-like , CG6620-PA , DmAuroraB , aurora , aurora B , aurora B kinase , aurora-B , auroraB , dAurora B , ial-PA , aurora/IPL1-related kinase 2 , serine/threonine-protein kinase 12 , serine/threonine-protein kinase aurora-B , xAurora-B , aurora kinase B , serine/threonine-protein kinase 12-like , ARK-2 , STK-1 , aurora 1 , aurora kinase B-Sv1 , aurora kinase B-Sv2 , aurora- and Ipl1-like midbody-associated protein 1 , aurora-1 , aurora-related kinase 2 , protein phosphatase 1, regulatory subunit 48 , serine/threonine kinase 12 , serine/threonine-protein kinase 5 , aurora- and IPL1-like midbody-associated protein 1 , serine/threonine kinase 5 , AIM-1 , Serine/threonine-protein kinase 12 , aurB , cei , cellular island , serine/threonine kinase a , I-kappa-B kinase 2 , I-kappa-B-kinase beta , IKK-B , IKK-beta , NFKBIKB , inhibitor of kappaB kinase beta , inhibitor of nuclear factor kappa B kinase beta subunit , inhibitor of nuclear factor kappa-B kinase subunit beta , nuclear factor NF-kappa-B inhibitor kinase beta

GENE ID SPEZIES
34504 Drosophila melanogaster
549613 Xenopus (Silurana) tropicalis
100301584 Oryzias latipes
100399490 Callithrix jacchus
100448258 Pongo abelii
100528532 Ictalurus punctatus
9212 Homo sapiens
20877 Mus musculus
114592 Rattus norvegicus
479492 Canis lupus familiaris
396955 Sus scrofa
360192 Bos taurus
455095 Pan troglodytes
791894 Danio rerio
84351 Rattus norvegicus
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