Reelin Proteine (RELN)

Bezeichnung:
Reelin Proteine (RELN)
Auf www.antikoerper-online.de finden Sie aktuell 17 Reelin (RELN) Proteine von 4 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Reelin Antikörper (50) und Reelin Kits (31) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 98 Reelin Produkte verfügbar.
Synonyme:
LIS2, MGC172539, PRO1598, Reelen, reeler, RELN, Rl
alle Proteine anzeigen Gen GeneID UniProt
RELN 19699 Q60841
RELN 5649 P78509
RELN 24718 P58751

Weitere Synonyme anzeigen

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Weitere Proteine zu Reelin Interaktionspartnern

Zebrafish Reelin (RELN) Interaktionspartner

  1. Developmental gene expression pattern of reelin, dab1 (zeige DAB1 Proteine), vldlr (zeige VLDLR Proteine), and apoer2 (zeige LRP8 Proteine) in the central nervous system of zebrafish was compared, and their remarkable expression was detected in the developing laminar structures and also non-laminated structures.

Mouse (Murine) Reelin (RELN) Interaktionspartner

  1. CHD7 (zeige CHD3 Proteine) is necessary for maintaining an open, accessible chromatin state at the Reln locus. Taken together, this study shows that Reln gene expression is regulated by chromatin remodeling, identifies CHD7 (zeige CHD3 Proteine) as a previously unrecognized upstream regulator of Reln, and provides direct in vivo evidence that a mammalian CHD (zeige CHRD Proteine) protein can control brain development

  2. ADAMTS-3 was identified as the protease that cleaves and inactivates Reelin in the cerebral cortex and hippocampus. ADAMTS-3 was expressed in the excitatory neurons of the embryonic and postnatal cerebral cortex and hippocampus.

  3. RELN R2290C heterozygous neurospheres reveals up-regulation of Protein Disulfide Isomerase (zeige P4HB Proteine) A1, best known as an endoplasmic reticulum-chaperone protein

  4. A C-terminal region truncation of the reelin protein causes abnormal phenotypes in the cerebral cortex and hippocampus.

  5. This study demonstrated that Reelin Maintain Postnatal CA1 (zeige CA1 Proteine) Hippocampus Integrity in mice.

  6. Sex-associated and brain region-specific differences in reelin expression appear long before Abeta (zeige APP Proteine)-plaque formation in AbetaPP mutant Alzheimer disease model.

  7. These findings suggest that circulating Reelin promotes atherosclerosis by increasing vascular inflammation, and that reducing or inhibiting circulating Reelin may present a novel approach for the prevention of cardiovascular disease.

  8. A new transgenic mouse model demonstrates that Reelin is a molecule which is critical for proper cortical development.

  9. androgenic hormones can influence cerebral reelin demethylation

  10. data suggest Kdm5b (zeige KDM5B Proteine) negatively regulates neurogenesis and represses reelin in neural stem cells from the adult subventricular zone.

Human Reelin (RELN) Interaktionspartner

  1. This study demonstrated that RELN DNA methylation (zeige HELLS Proteine) might contribute to the pathogenesis of schizophrenia.

  2. The present investigation, performed on a study sample from a population with one of the highest suicide rates in the world, indicated an association between rs2965087 in the reelin gene and the expression of suicidal threats a month before suicide in contrast to other symptoms of depression.

  3. Reelin is was low in primary breast cancer tissue, but higher in Her2 (zeige ERBB2 Proteine)(+) breast cancers (but not triple-negative ones) metastasizing to the brain, especially in the tumor periphery adjacent to surrounding astrocytes. In the neural niche, astrocytes epigenetically regulate Reelin expression and its interaction with Her2 (zeige ERBB2 Proteine) leading to increased proliferation and survival fitness.

  4. Heterozygous RELN mutations cause a typical Autosomal Dominant Lateral Temporal Lobe Epilepsy syndrome, indistinguishable from that associated with LGI1 (zeige LGI1 Proteine) mutations.

  5. We screened for mutations in RELN or VLDLR (zeige VLDLR Proteine) and compared the phenotype of these patients with that of previously reported patients. differences in clinical severity, involvement of the cerebellar hemispheres, together with the severity of the neocortical defect, enables RELN-mutated patients to be distinguished from VLDLR (zeige VLDLR Proteine)-mutated patients.

  6. Reelin signaling is a critical player in the modulation of synaptic function.

  7. Reelin was expressed by human hepatic stellate cells/myofibroblasts and the number of these cells increased significantly in the lobule as the liver fibrosis progressed, suggesting a role for Reelin in the activation of hepatic stellate cells/myofibroblasts during liver injury.

  8. The presence of reelin was elevated in junctional areas as in dysplastic nevi. VLDLR (zeige VLDLR Proteine) presented positive values in 16 cases (16/ 32) and ApoER2 (zeige LRP8 Proteine) was weak positive in 7 cases.

  9. common variants of GABRG2 (zeige GABRG2 Proteine), RELN and NRG3 (zeige NRG3 Proteine) and the GABRG2 (zeige GABRG2 Proteine)-RELN-PTCH1 (zeige PTCH1 Proteine) interaction networks might confer altered susceptibility to Hirschsprung disease.

  10. RELN is mapped at 7q22, which had been identified as a candidate region for autism by early genetic linkage study.

Pig (Porcine) Reelin (RELN) Interaktionspartner

  1. A peak in Reelin mRNA and protein expression is present in the pig embryonic brain during the period of major neurogenesis and neuronal migration.

Reelin (RELN) Protein Überblick

Protein Überblick

This gene encodes a large secreted extracellular matrix protein thought to control cell-cell interactions critical for cell positioning and neuronal migration during brain development. This protein may be involved in schizophrenia, autism, bipolar disorder, major depression and in migration defects associated with temporal lobe epilepsy. Mutations of this gene are associated with autosomal recessive lissencephaly with cerebellar hypoplasia. Two transcript variants encoding distinct isoforms have been identified for this gene. Other transcript variants have been described but their full length nature has not been determined.

Alternative names and synonyms associated with Reelin (RELN)

  • reelin (RELN)
  • reelin (reln)
  • reelin (Reln)
  • reelin-like (RELN)
  • LIS2 Protein
  • MGC172539 Protein
  • PRO1598 Protein
  • Reelen Protein
  • reeler Protein
  • RELN Protein
  • Rl Protein

Bezeichner auf Proteinebene für Reelin Proteine (RELN)

reelin , reelin-like , extracellular matrix serine protease , reelin, extracellular

GENE ID SPEZIES
100058621 Equus caballus
260303 Danio rerio
398547 Xenopus laevis
463635 Pan troglodytes
579060 Strongylocentrotus purpuratus
696372 Macaca mulatta
786373 Bos taurus
100013879 Monodelphis domestica
100049232 Oryzias latipes
100192371 Xenopus (Silurana) tropicalis
100403212 Callithrix jacchus
100480458 Ailuropoda melanoleuca
100552788 Anolis carolinensis
100593340 Nomascus leucogenys
19699 Mus musculus
5649 Homo sapiens
24718 Rattus norvegicus
427850 Gallus gallus
483273 Canis lupus familiaris
100127480 Sus scrofa
100723362 Cavia porcellus
281450 Bos taurus
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