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GRIK2 Proteine (GRIK2)

Bezeichnung:
Glutamate Receptor, Ionotropic, Kainate 2 Proteine (GRIK2)
Auf www.antikoerper-online.de finden Sie aktuell 11 Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2) Proteine von 5 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen GRIK2 Antikörper (87) und GRIK2 Kits (31) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 139 GRIK2 Produkte verfügbar.
Synonyme:
AW124492, EAA4, GLR6, GluK2, GLUK6, Glur-6, Glur6, Glurbeta2, GRIK2, grik2-A, GRIK5, MRT6
alle Proteine anzeigen Gen GeneID UniProt
GRIK2 2898 Q13002
Ratte GRIK2 GRIK2 54257 P42260
GRIK2 14806  

Weitere Synonyme anzeigen

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Weitere Proteine zu GRIK2 Interaktionspartnern

Human Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2) Interaktionspartner

  1. TTBK2 (zeige TTBK2 Proteine) down-regulates GluK2 activity by decreasing the receptor protein abundance in the cell membrane via RAB5 (zeige RAB5A Proteine)-dependent endocytosis.

  2. In the Han population in Central China, the polymorphisms of SNP rs9390754 in the GRIK2 gene may be associated with epilepsy susceptibility.

  3. Study demonstrates that co-assembly of recombinant kainate receptors (GluK1 (zeige GRIK1 Proteine) and GluK2) with the Neto1 (zeige NETO1 Proteine) and Neto2 (zeige NETO2 Proteine) auxiliary subunits alters their onset and recovery from desensitization in a subunit-dependent manner

  4. This study found in GRIK2 (glutamate (zeige GRIN1 Proteine) receptor, ionotropic kainate 2) was most significant and also showed significant correlations with gene expression.

  5. This study showed that Gluk2 association with obsessive-compulsive disorder.

  6. Parkin interac (zeige PARK2 Proteine)ts with the kainate receptor GluK2 subunit and regulates KAR function.

  7. High risk genetic markers of paranoid schizophrenia were GRIK2*ATG and GRIK2*TGG in Tatars.

  8. The present study reveals an additional mechanism for the regulation of GluK2-containing kainate receptors by Src (zeige SRC Proteine) family kinases, which may be of pathological significance in ischemic stroke.

  9. we found no association between rs1556995 in GRIK2 and clozapine-induced obsessive-compulsive (OC) symptoms, implying that that GRIK2 may not play a role in the development of OC symptoms in schizophrenia patients

  10. 14-3-3 (zeige YWHAQ Proteine) proteins are an important regulator of GluK2a-containing KARs (zeige KARS Proteine) and may contribute to the slow decay kinetics of native KAR (zeige HSD17B12 Proteine)-EPSCs.

Mouse (Murine) Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2) Interaktionspartner

  1. GluK2-mediated increase in KCC2 (zeige SLC12A5 Proteine) recycling to the surface membrane translates to a hyperpolarization of the reversal potential for GABA (EGABA).

  2. Loss of parkin (zeige PARK2 Proteine) function in primary cultured neurons causes GluK2 protein to accumulate in the plasma membrane.

  3. Interictal and ictal discharges are minimized in mice lacking the GluK2 subunit.

  4. 14-3-3 (zeige YWHAQ Proteine) proteins are an important regulator of GluK2a-containing KARs (zeige KARS Proteine) and may contribute to the slow decay kinetics of native KAR (zeige HSD17B12 Proteine)-EPSCs.

  5. This study demonistrated that grik2 gene expression in mouse dorsal raphe nucleus

  6. The results show that NETO2 (zeige NETO2 Proteine) is a kainate receptor subunit with significant effects on glutamate (zeige GRIN1 Proteine) signaling mechanisms in brain.

  7. GluR6 kainate receptors are critically involved in inhibiting transmission at both A delta and C fibre monosynaptic pathways. Presynaptic GluR5 (zeige GRIK1 Proteine) kainate receptors play limited role in inhibiting C fibre-activated pathway.

  8. Using kainate receptor knock-out mice, we show that subunits glutamate (zeige GRIN1 Proteine) receptor (GluR) 5 (zeige GRIK1 Proteine) and GluR6 play distinct roles in kainate-induced gamma oscillations and epileptiform burst activity.

  9. The facilitatory effects of kainate on mossy fiber synaptic transmission and plasticity are mediated by GLU (zeige GCG Proteine)(K6)-containing kainate receptors.

  10. In the present study, we used knock-out mice to explore the contribution of GluR5 (zeige GRIK1 Proteine) and GluR6 receptors to sensory responses, fear memory, and learning-related synaptic potentiation in the amygdala.

GRIK2 Protein Überblick

Protein Überblick

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation.

Alternative names and synonyms associated with GRIK2

  • glutamate receptor, ionotropic, kainate 2 (GRIK2)
  • glutamate receptor, ionotropic, kainate 2 (grik2-b)
  • glutamate receptor, ionotropic, kainate 2 (grik2)
  • glutamate receptor, ionotropic, kainate 2 (Grik2)
  • glutamate receptor, ionotropic, kainate 2 (beta 2) (Grik2)
  • glutamate receptor, ionotropic, kainate 5 (GRIK5)
  • AW124492 Protein
  • EAA4 Protein
  • GLR6 Protein
  • GluK2 Protein
  • GLUK6 Protein
  • Glur-6 Protein
  • Glur6 Protein
  • Glurbeta2 Protein
  • GRIK2 Protein
  • grik2-A Protein
  • GRIK5 Protein
  • MRT6 Protein

Bezeichner auf Proteinebene für GRIK2

glutamate receptor 6 , glutamate receptor, ionotropic kainate 2 , glutamate receptor, ionotropic, kainate 5 , bA487F5.1 , excitatory amino acid receptor 4 , gluR-6 , glutamate receptor form A , glutamate receptor form B , glutamate receptor form C , glutamate receptor form D , glutamate receptor form E , glutamate receptor ionotropic, kainate 2 , gluR beta-2 , glutamate receptor beta-2 , glutamate receptor, ionotropic, kainate 2

GENE ID SPEZIES
462899 Pan troglodytes
100294518 Xenopus laevis
378603 Xenopus laevis
2898 Homo sapiens
481938 Canis lupus familiaris
615226 Bos taurus
54257 Rattus norvegicus
556013 Danio rerio
100733104 Cavia porcellus
428628 Gallus gallus
101122701 Ovis aries
14806 Mus musculus
100356816 Oryctolagus cuniculus
100516526 Sus scrofa
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