anti-VANGL2 (VANGL2) Antikörper

anti-Vang-Like 2 (Van Gogh, Drosophila) Antikörper (VANGL2)
Auf finden Sie aktuell 74 Vang-Like 2 (Van Gogh, Drosophila) (VANGL2) Antikörper von 16 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen VANGL2 Kits (4) und VANGL2 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 85 VANGL2 Produkte verfügbar.
C530001F03Rik, loop-tail, Lp, LPP1, LTAP, ska17, ska, STB1, STBM, STBM1, strabismus, tri, vang, Vang1l2, VANGL2

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anti-Mouse (Murine) VANGL2 Antikörper:

anti-Human VANGL2 Antikörper:

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Am meisten referenzierte anti-VANGL2 Antikörper

  1. Mouse (Murine) Polyclonal VANGL2 Primary Antibody für WB - ABIN1881989 : Devenport, Fuchs: Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles. in Nature cell biology 2008 (PubMed)
    Zeige alle 5 Referenzen für 1881989

  2. Human Polyclonal VANGL2 Primary Antibody für ELISA, WB - ABIN190866 : Kibar, Vogan, Groulx, Justice, Underhill, Gros: Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail. in Nature genetics 2001 (PubMed)

Weitere Antikörper gegen VANGL2 Interaktionspartner

Mouse (Murine) Vang-Like 2 (Van Gogh, Drosophila) (VANGL2) Interaktionspartner

  1. Vangl2 is expressed in the inner dental epithelium (IDE (zeige IDE Antikörper)) and in the secondary enamel knots (SEKs) of bell stage tooth germs.

  2. a new and essential role for Vangl2-dependent planar cell polarity signaling in the intraretinal path-finding of retinal ganglion cell axons

  3. Vangl2-regulated polarisation and subsequent acquisition of an epithelial phenotype is essential to lengthen the tubular outflow vessel, a process that is essential for on-going cardiac morphogenesis (zeige XIRP1 Antikörper).

  4. Vangl2 regulates E-cadherin (zeige CDH1 Antikörper) in epithelial cells.

  5. Vangl2 function in podocytes is important for glomerular development and protects against glomerular injury in adult animals.

  6. Vangl1 (zeige Vangl1 Antikörper) and Vangl2 may play a key role in the embryo implantation of mice

  7. The first signal, controlled by cadherin, EGF (zeige EGF Antikörper)-like, laminin G-like, seven-pass, G-type receptor (Celsr) 2 (zeige CELSR2 Antikörper), Celsr3 (zeige CELSR3 Antikörper), Frizzled3 (Fzd3 (zeige FZD3 Antikörper)) and Van Gogh like2 (Vangl2) organizes multicilia in individual cells (single-cell polarity)

  8. Celsr2 (zeige CELSR2 Antikörper)-3 and Fzd3 (zeige FZD3 Antikörper) regulate axonal navigation in the forebrain by using mechanisms different from classical epithelial core planar cell polarity, and require interacting partners other than Vangl1 (zeige Vangl1 Antikörper)-2 that remain to be identified.

  9. Testin (zeige TES Antikörper) interacts with vangl2 genetically to regulate inner ear sensory cell orientation and the normal development of the female reproductive tract in mice.

  10. Apical boundary rearrangement is inhibited in Vangl2 mutant neural epithelium.

Zebrafish Vang-Like 2 (Van Gogh, Drosophila) (VANGL2) Interaktionspartner

  1. Results demonstrate that anterior guidance decisions by commissural primary ascending (CoPA (zeige COPA Antikörper)) axons are dependent on the function of planar cell polarity genes Fzd3a, Vangl2 and Scribble (zeige SCRIB Antikörper) both prior to and after midline crossing; experiments establish CoPA (zeige COPA Antikörper) axons as a model system to investigate the mechanism of planar cell polarity signaling in commissural axon guidance.

  2. dynamic Vangl2 intracellular distribution is coordinated with and necessary for the changes in convergence and extension cell behaviors during gastrulation

  3. we found that the critical period for Vangl2 function coincides with the initial stages of FBM neuron migration out of rhombomere 4.

  4. Vangl2 regulates FBM neuron migration by acting in floor plate cells, independently of cilia function

  5. VANGL2 regulates the endocytosis and cell-surface availability of MMP14 in a manner that is dependent on focal adhesion kinase.

  6. Vangl2(R259L) behaved like the wild-type allele in overexpression and morpholino knockdown/rescue assays in zebrafish embryos.

  7. Rack1 (zeige GNB2L1 Antikörper) has a dominant-negative effect on Vangl2 localization and gastrulation.

  8. data suggest that bbs8 (zeige TTC8 Antikörper) and vangl2 act synergistically on cell polarization to establish and maintain the appropriate length and number of cilia in the Kupffer's vesicle and thereby facilitate correct LR asymmetry

  9. Vangl2 is required for asymmetric localization and posterior tilting of primary motile cilia at the apical membrane of epithelial cells.

  10. show that anterior hindbrain (r2/r3) motor neuron migration appears to be independent of vangl2 and pk1b functions, and suggest that multiple mechanisms regulate motor neuron migration along the anterior-posterior axis of the zebrafish hindbrain

Human Vang-Like 2 (Van Gogh, Drosophila) (VANGL2) Interaktionspartner

  1. Our experimental data demonstrate that high expression of Prickle1 (zeige PRICKLE1 Antikörper) and Vangl2 reduce the growth of neuroblastoma (zeige ARHGEF16 Antikörper) cells and indicate different roles of PCP (zeige PRCP Antikörper) proteins in tumorigenic cells compared to normal cells.

  2. VANGL2 is overexpressed in basal breast cancers. It is involved in the proliferative signal cascade of the VANGL2-SQSTM1 (zeige SQSTM1 Antikörper)-JNK (zeige MAPK8 Antikörper) pathway.

  3. Propose that Arfrp1 (zeige ARFRP1 Antikörper) exposes a binding site on AP-1 (zeige FOSB Antikörper) that recognizes the Vangl2 sorting motif for capture into a transport vesicle destined for the proximal surface of a polarized epithelial cell.

  4. The aberrant VANGL2 promoter methylation and the decreased gene expression is associated with Tetralogy of Fallot.

  5. Asymmetry of VANGL2 in migrating lymphocytes as a tool to monitor activity of the mammalian WNT (zeige WNT2 Antikörper)/planar cell polarity pathway.

  6. Van-Gogh-like 2 is frequently methylated in MSI (zeige MSI1 Antikörper)-CRCs with BRAF (zeige BRAF Antikörper) mutation and may act as a tumour suppressor gene, counteracting WNT (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) signaling.

  7. these findings strongly implicate VANGL2 in the genetic causation of spinal NTDs in a subset of patients and provide additional evidence for a pathogenic role of PCP (zeige PRCP Antikörper) signaling in these malformations.

  8. Loss of membrane targeting of Vangl1 (zeige Vangl1 Antikörper) and Vangl2 proteins causes neural tube defects.

  9. The planar cell polarity genes Celsr1 (zeige CELSR1 Antikörper) and Vangl2 are required for normal lung branching morphogenesis.

  10. Van Gogh-Like 2 regulates tumor cell migration and matrix metalloproteinase-dependent invasion.

VANGL2 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a membrane protein involved in the regulation of planar cell polarity, especially in the stereociliary bundles of the cochlea. The encoded protein transmits directional signals to individual cells or groups of cells in epithelial sheets. This protein is also involved in the development of the neural plate.

Alternative names and synonyms associated with VANGL2

  • vang-like 2 (van gogh, Drosophila) (VANGL2) Antikörper
  • VANGL planar cell polarity protein 2 (vangl2) Antikörper
  • vang-like 2 (LOC100354291) Antikörper
  • vang-like 2 (van gogh, Drosophila) (Vangl2) Antikörper
  • vang-like 2 (van gogh, Drosophila) (vangl2) Antikörper
  • VANGL planar cell polarity protein 2 (VANGL2) Antikörper
  • VANGL planar cell polarity protein 2 (Vangl2) Antikörper
  • C530001F03Rik Antikörper
  • loop-tail Antikörper
  • Lp Antikörper
  • LPP1 Antikörper
  • LTAP Antikörper
  • ska17 Antikörper
  • ska Antikörper
  • STB1 Antikörper
  • STBM Antikörper
  • STBM1 Antikörper
  • strabismus Antikörper
  • tri Antikörper
  • vang Antikörper
  • Vang1l2 Antikörper
  • VANGL2 Antikörper

Bezeichner auf Proteinebene für VANGL2

vang-like 2 (van gogh, Drosophila) , Van Gogh , protein strabismus , van Gogh-like protein 2 , vang-like protein 2 , vang-like 2 , loop tail associated protein , loop-tail protein 1 , loop-tail-associated protein , vang (van gogh)-like 2 , protein trilobite , strabismus , trilobite , loop-tail protein 1 homolog , strabismus 1

610037 Canis lupus familiaris
426903 Gallus gallus
613073 Xenopus (Silurana) tropicalis
720239 Macaca mulatta
100354291 Oryctolagus cuniculus
93840 Mus musculus
245949 Danio rerio
520544 Bos taurus
57216 Homo sapiens
289229 Rattus norvegicus
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