MSI1 Proteine (MSI1)

Bezeichnung:
Musashi Homolog 1 (Drosophila) Proteine (MSI1)
Auf www.antikoerper-online.de finden Sie aktuell 5 Musashi Homolog 1 (Drosophila) (MSI1) Proteine von 4 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen MSI1 Antikörper (119) und MSI1 Kits (3) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 132 MSI1 Produkte verfügbar.
Synonyme:
anon-EST:Liang-2.35, CG5099, clone 2.35, Dmel\\CG5099, DMSIDNA, Dsim\\GD21224, dsim_GLEANR_4982, GD21224, m-Msi-1, msi, msi1h, Musahi1, musashi, Musashi-1, Musashi1, nrp-1B, SIDNA, XNrp-1
alle Proteine anzeigen Gen GeneID UniProt
MSI1 4440 O43347
MSI1 17690 Q61474
MSI1 259272 Q8K3P4

Weitere Synonyme anzeigen

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Weitere Proteine zu MSI1 Interaktionspartnern

Fruit Fly (Drosophila melanogaster) Musashi Homolog 1 (Drosophila) (MSI1) Interaktionspartner

  1. show specific evidence for a cell-autonomous requirement for Msi family proteins in regulating stem cell differentiation, leading to the identification of an RNA-binding protein required for spermatogonial stem cell maintenance

Human Musashi Homolog 1 (Drosophila) (MSI1) Interaktionspartner

  1. our results suggest a role for MSI1 in double-strand break repair and that its inhibition may enhance the effect of radiotherapy

  2. Results show that Meis1 (zeige MEIS1 Proteine) may have a positive feedback with Msi1 during the esophageal squamous cell carcinoma progression.

  3. Musashi-1 expression was higher in Barrett esophagus and early esophageal adenocarcinoma compared to advanced adenocarcinoma.

  4. miR (zeige MLXIP Proteine)-761 and MSI1 are inversely expressed in ovarian cancer tissues. In conclusion, we demonstrated that miR (zeige MLXIP Proteine)-761 repressed ovarian cancer proliferation and invasion by targeting MSI1

  5. Concomitant loss of function of both MSI1 is sufficient to abrogate the growth of human colorectal cancer cells, and Msi gene deletion inhibits tumorigenesis in several mouse models of intestinal cancer.

  6. Msi1 overexpression is associated with Esophageal Squamous Cell Carcinoma.

  7. studies highlight Msi reporters as a unique tool to identify therapy resistance, and define Msi signalling as a central regulator of pancreatic cancer

  8. Musashi-1 and ALDH1 (zeige ALDH1A1 Proteine) expression are closely related to metastasis of ovarian adenocarcinoma.

  9. Suggest high level of Musashi-1 protein expression is associated with poor survival in endometrioid adenocarcinoma patients.

  10. Our results demonstrate that miR (zeige MLXIP Proteine)-137 acts as a tumor-suppressive miRNA in colorectal cancers and negatively regulates oncogenic Musashi-1

Mouse (Murine) Musashi Homolog 1 (Drosophila) (MSI1) Interaktionspartner

  1. Msi-1 contributes to intestinal tumorigenesis driven by Apc (zeige APC Proteine) loss, and validate the pursuit of Msi-1 inhibitors as chemo-prevention agents to reduce tumor burden.

  2. Msi (zeige EBP Proteine) proteins are dispensable for normal homeostasis and self-renewal of the active intestinal stem cell.

  3. photoreceptors lack prototypical neuronal splicing factors and their splicing profile is driven to a significant degree by the Musashi 1 (MSI1) protein. A striking feature of the photoreceptor splicing program are exons that display a "switch-like" pattern of high inclusion levels in photoreceptors and near complete exclusion outside of the retina.

  4. Given that deregulated fatty acid metabolism plays a key role in kidney fibrosis, these results demonstrate a novel connection between fatty acid and Msi1, an RNA-binding protein, in kidney fibrosis

  5. A Mouse Model of Targeted Musashi1 Expression in Whole Intestinal Epithelium Suggests Regulatory Roles in Cell Cycle and Stemness.

  6. studies highlight Msi (zeige EBP Proteine) reporters as a unique tool to identify therapy resistance, and define Msi (zeige EBP Proteine) signalling as a central regulator of pancreatic cancer

  7. the RNA-binding protein Musashi 1 competes with miR130a and -206 for interaction with tachykinin mRNA

  8. MSI1 and MSI2 (zeige MSI2 Proteine) display distinct expression profiles during mammalian folliculogenesis and that MSI2 (zeige MSI2 Proteine) is required for pre-antral follicle development

  9. Osteoarticular expression of Msi1 protein is increased in joints with CIA (zeige NCOA5 Proteine)-induced lesion and absent in nonlesioned joints, suggesting that this protein is expressed when the lesion is produced in order to favor tissue repair.

  10. Msi1 is critical for constructing functional blood-testis barrier &maintaining spermatogenesis. Msi1 regulates Sertoli cell fate following heat-induced injury, likely through induction of stress granule formation & activation of p-ERK1/2 signaling

Xenopus laevis Musashi Homolog 1 (Drosophila) (MSI1) Interaktionspartner

  1. Genome-wide analysis of CPEB1- and Msi1-associated mRNAs identified 491 common targets, thus revealing a new layer of cytoplasmic polyadenylation elements-mediated translational control.

  2. specific association of Musashi with the noncanonical poly(A) polymerase (zeige PAPOLA Proteine) germ line development defective-2 (GLD2 (zeige PAPD4 Proteine))

  3. Xenopus Musashi proteins regulate translation of the Musashi1 mRNA during oocyte maturation.

  4. Ringo/cyclin-dependent kinase (zeige CDK1 Proteine) and mitogen-activated protein kinase (zeige MAPK1 Proteine) signaling pathways regulate the activity of the cell fate determinant Musashi to promote cell cycle re-entry in Xenopus oocytes.

  5. These findings indicate that Musashi function is necessary to establish the temporal order of maternal mRNA translation during Xenopus meiotic cell cycle progression.

  6. Msi-1 expression is upregulated in the adult progenitor cells and plays important roles in their maintenance and/or active proliferation during amphibian gastrointestinal remodeling.

  7. Visual deprivation for 2 days increased proliferation of musashi1-immunoreactive radial glial progenitors

MSI1 Protein Überblick

Protein Überblick

This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas. A pseudogene for this gene is located on chromosome 11q13.

Alternative names and synonyms associated with MSI1

  • musashi (msi)
  • musashi RNA-binding protein 1 (msi1)
  • GD21224 gene product from transcript GD21224-RA (Dsim\\msi)
  • musashi 1 (LOC100352797)
  • musashi homolog 1 (Drosophila) (MSI1)
  • musashi RNA-binding protein 1 (MSI1)
  • musashi RNA-binding protein 1 (Msi1)
  • anon-EST:Liang-2.35 Protein
  • CG5099 Protein
  • clone 2.35 Protein
  • Dmel\\CG5099 Protein
  • DMSIDNA Protein
  • Dsim\\GD21224 Protein
  • dsim_GLEANR_4982 Protein
  • GD21224 Protein
  • m-Msi-1 Protein
  • msi Protein
  • msi1h Protein
  • Musahi1 Protein
  • musashi Protein
  • Musashi-1 Protein
  • Musashi1 Protein
  • nrp-1B Protein
  • SIDNA Protein
  • XNrp-1 Protein

Bezeichner auf Proteinebene für MSI1

CG5099-PA , CG5099-PB , CG5099-PC , CG5099-PD , CG5099-PE , CG5099-PF , CG5099-PH , msi-PA , msi-PB , msi-PC , msi-PD , msi-PE , msi-PF , msi-PH , mushashi , musashi homolog 1 , Musashi 1 , Dsim\\GD21224-PA , Dsim\\msi-PA , GD21224-PA , msi , musashi 1 , RNA-binding protein Musashi homolog 1 , RNA-binding protein Musashi-1 , musashi-1 , musashi1 , Musashi homolog 1(Drosophila) , nrp-1B

GENE ID SPEZIES
43087 Drosophila melanogaster
496961 Xenopus (Silurana) tropicalis
6729631 Drosophila simulans
100352797 Oryctolagus cuniculus
527436 Bos taurus
4440 Homo sapiens
17690 Mus musculus
259272 Rattus norvegicus
399271 Xenopus laevis
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