Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Alle Spezies anzeigen
Weitere Synonyme anzeigen
Select your species
Mouse (Murine) EPAS1 ELISA Kit für Sandwich ELISA - ABIN426617
Cockle, Rajani, Zaidi, Kottke, Thompson, Diaz, Shim, Peterson, Parney, Short, Selby, Ilett, Melcher, Vile: Combination viroimmunotherapy with checkpoint inhibition to treat glioma, based on location-specific tumor profiling. in Neuro-oncology 2016
Over-expression of HIF-2alpha induced apoptosis in HCC (zeige FAM126A ELISA Kits) cells and increased the levels of pro-apoptotic proteins, Bak (zeige BAK1 ELISA Kits), ZBP-89 (zeige ZNF148 ELISA Kits) and PDCD4 (zeige PDCD4 ELISA Kits), whereas the inhibition of HIF-2alpha expression achieved opposite results. HIF-2alpha was decreased and played an anti-tumorigenic role in hepatocellular carcinoma.
Probiotic Bifidobacterium bifidum MIMBb75 may help attenuating EPAS1 overexpression associated with intestinal inflammation.
Data suggest that HIF2alpha mediates hypoxia-induced cancer growth/metastasis and that EFEMP1 (zeige FBLN3 ELISA Kits) is a downstream effector of hypoxia-induced HIF2alpha during breast tumorigenesis.
intestine HIF-2alpha regulates ceramide metabolism mainly from the salvage pathway, by positively regulating the expression of Neu3 (zeige Neu3 ELISA Kits), the gene encoding neuraminidase 3 (zeige Neu3 ELISA Kits). These results suggest that intestinal HIF-2alpha could be a viable target for hepatic steatosis therapy
demonstrated that MM cells are resistant to hypoxia-mediated apoptosis in vivo and in vitro, and that constitutive expression of HIF2alpha contributed to this resistance
HIF1A (zeige HIF1A ELISA Kits) and EPAS1 potentiate hypoxia-induced upregulation of INHA (zeige INHA ELISA Kits) expression in human term cytotrophoblasts in vitro.
Data show there was a significant negative correlation between PHGDH (zeige PHGDH ELISA Kits) copy-number alteration and EPAS1 (HIF2A) expression.
positive and bilateral HIF2-EGFR (zeige EGFR ELISA Kits) regulatory crosstalk promotes antiestrogen resistance in estrogen receptor alpha (zeige ESR1 ELISA Kits)-positive breast cancer
NAP peptide prevents outer blood retinal barrier breakdown by reducing HIF1alpha (zeige HIF1A ELISA Kits)/HIF2alpha, VEGF (zeige VEGFA ELISA Kits)/VEGFRs, and increasing HIF3alpha expression Moreover it is able to reduce the percentage of apoptotic cells by modulating the expression of two death related genes, BAX (zeige BAX ELISA Kits) and Bcl2 (zeige BCL2 ELISA Kits).
Data identify a previously unrecognized cellular process associated with hypoxia, and suggests that in vivo tumour hypoxia determines copper isotope fractionation in hepatocellular carcinoma and demonstrate that this effect of hypoxia is pH, HIF-1 (zeige HIF1A ELISA Kits) and -2 independent.
endothelial EPAS1 has a global protective role during glomerular hypertensive injuries without influencing the hypertensive effect of angiotensin II
findings indicate that HIF-2alpha increases cancer cell growth by up-regulating YAP1 (zeige YAP1 ELISA Kits) activity
Chronic activity of HIF2 in stromal progenitors impairs kidney development. Finally, these data confirm the concept that normal stroma function is essential for normal tubular differentiation.
this study shows that HIF-2alpha acts in resting macrophages as a phagocytosis suppressor implying an important relationship between the levels of HIF-2alpha and susceptibility to infection
in neurons HIF-1 (zeige HIF1A ELISA Kits) and HIF-2 have redundant functions for cellular survival under ischemic conditions. By contrast, lack of anti-survival factors in Hif1a (zeige HIF1A ELISA Kits)/Hif2a-deficient mice might protect from early acute neuronal cell death and neurological impairment, indicating a benefit of HIF-pathway inhibition in neurons in the very acute phase after ischemic stroke
HIF-2alpha is a novel regulator of neutrophil recruitment to colon tumors.
AQP1 (zeige AQP1 ELISA Kits) deficiency delays long-term ischemia-reperfusion resolution, partly through repressing angiogenesis mediated by destabilizing HIF-2alpha.
HIF1alpha (zeige HIF1A ELISA Kits) and HIF2alpha are dispensable for muscle stem cell function under normoxia but are required for maintaining satellite cell self-renewal in hypoxic environments.
eIF3e (zeige EIF3E ELISA Kits) is an angiogenesis suppressor. Silencing of eIF3e (zeige EIF3E ELISA Kits) promotes blood perfusion recovery after limb ischemia through stabilization of hypoxia-inducible factor 2alpha activity.
immunostaining for HIF-1alpha (zeige HIF1A ELISA Kits) and HIF-2alpha was observed during endochondral ossification; only HIF-2alpha was present at sites of intramembranous ossification
There was an association of an EPAS1 (HIF2alpha) double variant in the oxygen degradation domain of EPAS1 in Angus cattle with high altitude pulmonary hypertension (HAPH). There was upregulation of 26 of 27 HIF2alpha target genes in EPAS1 carriers with HAPH.
This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4.
endothelial PAS domain protein 1
, endothelial PAS domain-containing protein 1-like
, HIF-1-alpha-like factor
, HIF-1alpha-like factor
, PAS domain-containing protein 2
, basic-helix-loop-helix-PAS protein MOP2
, class E basic helix-loop-helix protein 73
, endothelial PAS domain-containing protein 1
, hypoxia-inducible factor 2 alpha
, hypoxia-inducible factor 2-alpha
, member of PAS protein 2
, HIF-related factor
, HIF1 alpha-like factor
, HIF1alpha-like factor
, HLF (HIF1alpha-like factor)
, Hif like protein
, hypoxia inducible transcription factor 2alpha
, HIF-2 alpha
, HIF2 alpha
, hypoxia inducible factor 2, alpha subunit
, hypoxia inducible factor 2a