WDR1 Proteine (WDR1)

Auf www.antikoerper-online.de finden Sie aktuell 8 WD Repeat Domain 1 (WDR1) Proteine von 5 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen WDR1 Antikörper (41) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 57 WDR1 Produkte verfügbar.
Aip1, D5Wsu185e, NORI-1, rede
alle Proteine anzeigen Gen GeneID UniProt
WDR1 9948 O75083
Maus WDR1 WDR1 22388 O88342
Ratte WDR1 WDR1 360950 Q5RKI0

WDR1 Proteine (WDR1) nach Spezies

Weitere Proteine zu WDR1 Interaktionspartnern

Human WD Repeat Domain 1 (WDR1) Interaktionspartner

  1. MRTF-A-miR (zeige MLXIP Proteine)-206-WDR1 form feedback loop to regulate breast cancer cell migration.

  2. homozygous missense L153F/L293F mutation in the actin regulatory gene WDR1 causes a new autoinflammatory disease in humans, with periodic fevers, immunodeficiency, and intermittent thrombocytopenia (PFIT).

  3. These data suggest that WDR1 plays an important role in suppressing platelet activity, where it alters the actin cytoskeleton dynamics, and downregulation of WDR1 may contribute to the platelet-mediated pathogenesis of cardiovascular disease.

  4. Mutations in WDR1 affect neutrophil morphology, motility, and function, causing a novel primary immunodeficiency

  5. Identify positive correlations between WDR1 and CLNK (zeige CLNK Proteine) gene polymorphisms in Chinese-Tibetan gout populations.

  6. Demonstrate a previously unanticipated role of Aip1 (zeige BIRC3 Proteine) in regulating the structure and remodeling of intestinal epithelial junctions and early steps of epithelial morphogenesis.

  7. When maternal environmental tobacco smoke was considered, fifteen of 135 single nucleotide polymorphism (SNPs) mapping to SLC2A9 and 9 of 59 SNPs in WDR1 gave P values approaching genome-wide significance.

  8. Data suggest that anti-WD repeat domain 1 (WDR1) antibody could be applied for serological screening of papillary thyroid carcinoma (PTC (zeige F9 Proteine)) and undifferentiated thyroid carcinoma (UTC), and could be an efficient and inexpensive biomarker.

  9. WD repeat-containing protein 1 was confirmed as being significantly overexpressed in interstitial fluid from ovarian carcinomas compared to healthy ovarian tissue.

  10. Studies suggest that vascular endothelial growth factor may be responsible for upregulated P-glycoprotein expression.

Mouse (Murine) WD Repeat Domain 1 (WDR1) Interaktionspartner

  1. WDR1 interacts with Lim domain kinase 1 (LIMK1 (zeige LIMK1 Proteine)), a well known phosphorylation kinase of Cofilin (zeige CFL1 Proteine).

  2. Wdr1 and cofilin (zeige CFL1 Proteine)/destrin (zeige DSTN Proteine)-mediated actomyosin remodelling are essential for generating or maintaining cortical tension within the developing epidermal sheet and driving the cell shape and planar orientation changes.

  3. Wdr1-regulated actin dynamics play essential roles in heart function in mice. F-actin accumulations caused by Wdr1 deletion result in disruption of sarcomeric structure.

  4. The QKI (zeige QKI Proteine) RNA-binding proteins regulate oligodendrocyte differentiation by modulating the expression of AIP-1.

  5. studies establish an essential requirement for Wdr1 in megakaryocytes and neutrophils

WDR1 Protein Überblick

Protein Überblick

This gene encodes a protein containing 9 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, mostly including a trp-asp at the C-terminal end. WD domains are involved in protein-protein interactions. The encoded protein may help induce the disassembly of actin filaments. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with WDR1

  • WD repeat domain 1 (WDR1)
  • WD repeat domain 1 (Wdr1)
  • Aip1 Protein
  • D5Wsu185e Protein
  • NORI-1 Protein
  • rede Protein

Bezeichner auf Proteinebene für WD Repeat Domain 1 Proteine (WDR1)

AIP1 , WD repeat-containing protein 1 , actin-interacting protein 1 , WD40 repeat protein 1 , WD repeat protein 1

422842 Gallus gallus
9948 Homo sapiens
533223 Bos taurus
22388 Mus musculus
360950 Rattus norvegicus
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