anti-SLC12A2 (SLC12A2) Antikörper

Bezeichnung:
anti-Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 2 Antikörper (SLC12A2)
Auf www.antikoerper-online.de finden Sie aktuell 97 Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 2 (SLC12A2) Antikörper von 16 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen SLC12A2 Proteine (9) und SLC12A2 Kits (2) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 114 SLC12A2 Produkte verfügbar.
Synonyme:
9330166H04Rik, BSC, bsc2, mBSC2, Nkcc1, sy-ns
Alle Antikörper anzeigen Gen GeneID UniProt
SLC12A2 6558 P55011
SLC12A2 83629  
SLC12A2 20496 P55012

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Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-SLC12A2 (SLC12A2) Antikörper

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anti-Human SLC12A2 Antikörper:

anti-Rat (Rattus) SLC12A2 Antikörper:

anti-Mouse (Murine) SLC12A2 Antikörper:

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Am meisten referenzierte anti-SLC12A2 Antikörper

  1. Cow (Bovine) Polyclonal SLC12A2 Primary Antibody für WB - ABIN2773831 : Panet, Eliash, Atlan: Na+/K+/Cl- cotransporter activates MAP-kinase cascade downstream to protein kinase C, and upstream to MEK. in Journal of cellular physiology 2005 (PubMed)
    Zeige alle 3 Referenzen für 2773831

  2. Human Polyclonal SLC12A2 Primary Antibody für EIA, IHC (fro) - ABIN1109023 : Hannemann, Flatman: Phosphorylation and transport in the Na-K-2Cl cotransporters, NKCC1 and NKCC2A, compared in HEK-293 cells. in PLoS ONE 2011 (PubMed)

  3. Human Polyclonal SLC12A2 Primary Antibody für ELISA, IHC - ABIN4339820 : Pawelczyk, Van Laer, Fransen, Rajkowska, Konings, Carlsson, Borg, Van Camp, Sliwinska-Kowalska: Analysis of gene polymorphisms associated with K ion circulation in the inner ear of patients susceptible and resistant to noise-induced hearing loss. in Annals of human genetics 2009 (PubMed)

Weitere Antikörper gegen SLC12A2 Interaktionspartner

Human Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 2 (SLC12A2) Interaktionspartner

  1. we introduce the molecular mechanism by which flavonoids, specifically quercetin, act through elevation of [Cl(-) ]c via activation of NKCC1 on important factors controlling various body and cellular functions, such as (1) antihypertensive actions controlling blood volume dependent on the amounts of renal Na(+) reabsorption via expression of the epithelial Na(+) channel

  2. NKCC1 and KCCs are coordinately regulated by L-WNK1 (zeige WNK1 Antikörper) isoforms.

  3. We also discovered and replicated three genome-wide significant variants in previously unreported loci for RDW (SLC12A2 rs17764730, PSMB5 (zeige PSMB5 Antikörper) rs941718), and hematocrit (PROX1 (zeige PROX1 Antikörper) rs3754140) and an upstream anti-sense long-noncoding RNA, LINC01184, as the likely causal variant

  4. NKCC1 high expression predicted a bad clinical outcome for lung adenocarcinoma patients and EGFR (zeige EGFR Antikörper)-mutated subgroup. Therefore, NKCC1 may play a role in lung adenocarcinoma and novel therapeutic tactics could be developed by targeting NKCC1 protein.

  5. Study describes a functional missense variant in SLC12A2 in human schizophrenia, and suggest that genetically encoded dysregulation of NKCC1 may be a risk factor for, or contribute to the pathogenesis of, schizophrenia

  6. The NKCC-1 is a Na(+)- dependent Cl(-) transporter that mediates the movement of Na(+), K(+), and Cl(-) ions across the plasma membrane and maintains cell volume and intracellular K(+) and Cl(-) homeostasis.

  7. NKCC1 labeling was seen only in the basolateral membrane of the secretory coils.

  8. Suggest that the expression of NKCC1 in esophageal squamous cell carcinoma may affect the G2/M checkpoint and may be related to the degree of histological differentiation of SCCs.

  9. Functional expression of human NKCC1 from a synthetic cassette-based cDNA: introduction of extracellular epitope tags and removal of cysteines.

  10. our data show a novel role for the WNK1 (zeige WNK1 Antikörper)/OSR1 (zeige OXSR1 Antikörper)/NKCC1 pathway in glioma migration

Mouse (Murine) Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 2 (SLC12A2) Interaktionspartner

  1. Study suggests that astaxanthin may exert neuroprotection following traumatic brain injury by ameliorating AQP4 (zeige AQP4 Antikörper)/NKCC1-mediated cerebral edema, and NKCC1 inactivation inhibitions the upregulation of AQP4 (zeige AQP4 Antikörper) after traumatic brain injury.

  2. GABAA (zeige GABRg1 Antikörper) receptor (GABAAR (zeige GABRG2 Antikörper)) and the Na(+)-K(+)-2Cl(-) cotransporter (zeige SLC12A1 Antikörper) (NKCC1), but not the K(+)-Cl(-) cotransporter (zeige SLC12A4 Antikörper) (KCC2 (zeige SLC12A5 Antikörper)), were expressed in the terminals of the CRH (zeige CRH Antikörper) neurons at the median eminence (ME). In contrast, CRH (zeige CRH Antikörper) neuronal somata were enriched with KCC2 (zeige SLC12A5 Antikörper) but not with NKCC1.

  3. These results identify NKCC1 as a novel target for Nedd4L (zeige NEDD4L Antikörper)-mediated down-regulation in vivo, which modulates ion and fluid transport in the distal colon together with epithelial Na(+) channel (ENaC (zeige SCNN1A Antikörper)).

  4. NKCC1 inhibition protects neurons from traumatic brain injury via regulation of the ERK (zeige EPHB2 Antikörper) signal pathway.

  5. We conclude that TRPV2 (zeige TRPV2 Antikörper) is involved in osmosensation in skeletal muscle fibres, acting in concert with P-SPAK (zeige STK39 Antikörper)-activated NKCC1

  6. KCC2 (zeige SLC12A5 Antikörper) expression supersedes NKCC1 in mature fiber cells in mouse and rabbit lenses.

  7. GnRH (zeige GNRH1 Antikörper) neurons were immunopositive for NKCC1 and AE2 (zeige SLC4A2 Antikörper).

  8. NKCC1 may have a role in periventricular leukomalacia, as shown by bumetanide protection against white matter injury in a rodent model

  9. our results suggest that NKCCs are involved in insulin (zeige INS Antikörper) secretion and that a single Slc12a2 allele may protect beta-cells from failure due to increased homeostatic expression of Slc12a1 (zeige SLC12A1 Antikörper).

  10. Repeated stress decreased KCC2 (zeige SLC12A5 Antikörper) expression and increased NKCC1 expression in membranes of granular and pyramidal cells in the hippocampus.

SLC12A2 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene mediates sodium and chloride transport and reabsorption. The encoded protein is a membrane protein and is important in maintaining proper ionic balance and cell volume. This protein is phosphorylated in response to DNA damage. Three transcript variants encoding two different isoforms have been found for this gene.

Alternative names and synonyms associated with SLC12A2

  • solute carrier family 12 (sodium/potassium/chloride transporters), member 2 (SLC12A2) Antikörper
  • solute carrier family 12 (sodium/potassium/chloride transporter), member 2 (SLC12A2) Antikörper
  • solute carrier family 12 (sodium/potassium/chloride transporter), member 2 (Slc12a2) Antikörper
  • solute carrier family 12, member 2 (Slc12a2) Antikörper
  • 9330166H04Rik Antikörper
  • BSC Antikörper
  • bsc2 Antikörper
  • mBSC2 Antikörper
  • Nkcc1 Antikörper
  • sy-ns Antikörper

Bezeichner auf Proteinebene für SLC12A2

solute carrier family 12 (sodium/potassium/chloride transporters), member 2 , solute carrier family 12 member 2-like , basolateral Na-K-Cl symporter , bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1 , solute carrier family 12 member 2 , solute carrier family 12, member 2 , basolateral NaK(2Cl) cotransporter , sodium/potassium/chloride cotransporters , sodium/potassium/chloride transporters

GENE ID SPEZIES
100464321 Ailuropoda melanoleuca
6558 Homo sapiens
83629 Rattus norvegicus
286845 Bos taurus
481490 Canis lupus familiaris
20496 Mus musculus
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