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KCNE1 Proteine (KCNE1)

Bezeichnung:
Potassium Voltage-Gated Channel, Isk-Related Family, Member 1 Proteine (KCNE1)
Auf www.antikoerper-online.de finden Sie aktuell 8 Potassium Voltage-Gated Channel, Isk-Related Family, Member 1 (KCNE1) Proteine von 3 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen KCNE1 Antikörper (65) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 78 KCNE1 Produkte verfügbar.
Synonyme:
IsK, JLNS, JLNS2, KCNE1, LQT2/5, LQT5, m, minK, nmf190, xkcne1
alle Proteine anzeigen Gen GeneID UniProt
KCNE1 3753 P15382
KCNE1 25471 P15383
KCNE1 16509 P23299

Weitere Synonyme anzeigen

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Weitere Proteine zu KCNE1 Interaktionspartnern

Xenopus laevis Potassium Voltage-Gated Channel, Isk-Related Family, Member 1 (KCNE1) Interaktionspartner

  1. TNIK (Traf2 and Nck-interacting kinase (zeige TNIK Proteine)) and MINK (Misshapen/NIKs-related kinase) MAP4K signalling kinases are integral components of both canonical and non-canonical pathways in Xenopus.

  2. KCNE1/KCNQ1 (zeige KCNQ1 Proteine) was expressed in Xenopus oocytes with and without beta-catenin (zeige CTNNB1 Proteine). Confocal microscopy revealed that beta-catenin (zeige CTNNB1 Proteine) enhanced the KCNE1/KCNQ1 (zeige KCNQ1 Proteine) protein abundance in the cell membrane.

  3. PIP(2) has a role in KCNE1 modulation of I(Ks) channels that may represent a common mechanism of auxiliary subunit modulation of many ion channels

  4. characterize a new component of the early bioelectrical circuit: the potassium channel (zeige KCNAB2 Proteine) KCNQ1 (zeige KCNQ1 Proteine) and its accessory subunit KCNE1

  5. phenylboronic acid (PBA) activates KCNQ1 (zeige KCNQ1 Proteine)/KCNE1 complexes

Human Potassium Voltage-Gated Channel, Isk-Related Family, Member 1 (KCNE1) Interaktionspartner

  1. Sphingomyelin synthase 1 (zeige SGMS1 Proteine) positively regulates KCNQ1 (zeige KCNQ1 Proteine)/KCNE1 channel density in a protein kinase D (zeige PRKD1 Proteine)-dependent manner.

  2. Receptor Species-dependent Desensitization Controls KCNQ1 (zeige KCNQ1 Proteine)/KCNE1 K+ Channels as Downstream Effectors of Gq Protein-coupled Receptors.(

  3. KCNE1 encodes a modulator of KCNQ1 (zeige KCNQ1 Proteine) and KCNH2 (zeige KCNH2 Proteine) channels. Long QT syndrome (LQTS) patients with KCNE1(G38S) had a rate-dependent repolarization abnormality similar to patients with LQT2 (zeige KCNH2 Proteine) and, therefore, may have a potential risk to develop lethal arrhythmias.

  4. A stoichiometry of 4:4 between the alpha KCNE1 and the beta KCNQ1 (zeige KCNQ1 Proteine)-subunits has been established.

  5. Analysis of QT-RR relationship could also evaluate the latent arrhythmogenicity of KCNE1(G38S).

  6. The incidence of AF among the senior Uygur population in Xinjiang territory was correlated with the KCNE1 (G38S) polymorphism, which may be an independent risk factor for Uygur AF patients.

  7. The KCNQ1 (zeige KCNQ1 Proteine) F279I mutation induces a gain of function of IKs due to an impaired gating modulation of Kv7.1 (zeige KCNQ1 Proteine) induced by KCNE1, leading to a shortening of the cardiac action potential

  8. This study aimed to assess the associations between polymorphisms on KCNE1, KCNQ1 (zeige KCNQ1 Proteine), and KCNH2 (zeige KCNH2 Proteine) with the risk of AF in a Chinese population.

  9. KCNE1 and KCNE3: The yin and yang of voltage-gated K(+) channel (zeige KCND3 Proteine) regulation

  10. Two phenylalanine residues on KCNQ1 (zeige KCNQ1 Proteine), Phe232 on S4 (VSD) and Phe279 on S5 (pore domain) to be responsible for the gating modulation by KCNE1.

Pig (Porcine) Potassium Voltage-Gated Channel, Isk-Related Family, Member 1 (KCNE1) Interaktionspartner

  1. study demonstrated that in the left ventricle,the level of the transcriptional product of KCNE1 was significantly higher than those of KCNQ1 (zeige KCNQ1 Proteine), KCNH2 (zeige KCNH2 Proteine), and KCNE2 (zeige KCNE2 Proteine)

Rabbit Potassium Voltage-Gated Channel, Isk-Related Family, Member 1 (KCNE1) Interaktionspartner

  1. miR-1 by anti-miR-1 inhibitor oligonucleotides alleviated the downregulation of KCNE1 and KCNB2 (zeige KCNB2 Proteine), the shortening of AERP, and the increase in the IKs

Cow (Bovine) Potassium Voltage-Gated Channel, Isk-Related Family, Member 1 (KCNE1) Interaktionspartner

  1. The localization of KCNE1 in the RPE (zeige RPE Proteine) basal membrane, where KCNQ5 (zeige KCNQ5 Proteine) was previously found to be present, suggests that this beta-subunit (zeige POLG Proteine) may contribute to M-type K(+) channels in this membrane.

Mouse (Murine) Potassium Voltage-Gated Channel, Isk-Related Family, Member 1 (KCNE1) Interaktionspartner

  1. The electrophysiological effects of BACE1 (zeige BACE Proteine) on KCNQ1 (zeige KCNQ1 Proteine) reported here were independent of its enzymatic activity.

  2. KCNE1 and KCNE3: The yin and yang of voltage-gated K(+) channel (zeige KCND3 Proteine) regulation

  3. KCNE1 and KCNE2 (zeige KCNE2 Proteine), auxiliary subunits of voltage-gated potassium channels, undergo sequential cleavage mediated by either alpha-secretase and presenilin(PS)/gamma-secretase or BACE1 (zeige BACE Proteine) and PS/gamma-secretase in cells.

  4. In clearance studies the KCNE1 knockout mice had an increased fractional excretion of Na+, Cl-, HCO3(-) and water.

  5. This study confirmed that KCNE1 channels are necessary for K+ secretion in developmental Saccule and Utricle in mice.

  6. both the voltage-dependence and kinetics of gating were found to depend on the relative densities of KCNQ1 (zeige KCNQ1 Proteine) and KCNE1, suggesting the heart rhythm may be regulated by the relative expression of the auxiliary subunit

  7. Findings directly implicate triggered electrical activity and spatial and temporal re-entrant mechanisms in the arrhythmogenesis observed in KCNE1 (-/-) hearts.

  8. intestinal Cl(-) secretion is independent from KCNE1 but requires KCNQ1 (zeige KCNQ1 Proteine) and in mouse pancreatic acini KCNQ1 (zeige KCNQ1 Proteine) probably co-assembled with KCNE1 leads to a voltage-dependent K(+) current that might be of importance for electrolyte and enzyme secretion.

  9. the spatial expression of minK-lacZ (zeige GLB1 Proteine) in the adult mouse heart has been shown, for the larger part, to be coincident with the conduction tissues

  10. The transitory transfection of kcne1 restores both Cl- and K+ swelling-activated currents, confirming the implication of KCNE1 protein in the cell-volume regulation in PCT (zeige UROD Proteine) cells in primary cultures.

KCNE1 Protein Überblick

Protein Überblick

The product of this gene belongs to the potassium channel KCNE family. Potassium ion channels are essential to many cellular functions and show a high degree of diversity, varying in their electrophysiologic and pharmacologic properties. This gene encodes a transmembrane protein known to associate with the product of the KVLQT1 gene to form the delayed rectifier potassium channel. Mutation in this gene are associated with both Jervell and Lange-Nielsen and Romano-Ward forms of long-QT syndrome. Alternatively spliced transcript variants encoding the same protein have been identified.

Alternative names and synonyms associated with KCNE1

  • potassium voltage-gated channel, Isk-related family, member 1 (kcne1)
  • potassium voltage-gated channel, Isk-related family, member 1 (KCNE1)
  • potassium voltage-gated channel, Isk-related family, member 1 (Kcne1)
  • potassium voltage-gated channel, Isk-related subfamily, member 1 (Kcne1)
  • IsK Protein
  • JLNS Protein
  • JLNS2 Protein
  • KCNE1 Protein
  • LQT2/5 Protein
  • LQT5 Protein
  • m Protein
  • minK Protein
  • nmf190 Protein
  • xkcne1 Protein

Bezeichner auf Proteinebene für KCNE1

potassium voltage-gated channel, Isk-related family, member 1 , voltage-gated potassium channel subunit MinK , potassium voltage-gated channel subfamily E member 1 , IKs producing slow voltage-gated potassium channel subunit beta Mink , cardiac delayed rectifier potassium channel protein , delayed rectifier potassium channel subunit IsK , minimal potassium channel , potassium voltage-gated channel, Isk-related subfamily, member 1 , voltage gated potassiun channel accessory subunit , mink , potassium (K+) channel protein, slowly activating (Isk) , potassium voltage-gated channel Shaw-related subfamily member 1 , delayed rectifier potassium channel protein , slow delayed rectifier K+ channel , voltage gated potassium channel accessory subunit cardiac splice , mISK

GENE ID SPEZIES
398417 Xenopus laevis
427980 Gallus gallus
474097 Pan troglodytes
100173028 Pongo abelii
3753 Homo sapiens
25471 Rattus norvegicus
493681 Felis catus
397331 Sus scrofa
100126000 Oryctolagus cuniculus
487743 Canis lupus familiaris
528014 Bos taurus
16509 Mus musculus
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