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GLUT1 Proteine (SLC2A1)

Bezeichnung:
Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 1 Proteine (SLC2A1)
Auf www.antikoerper-online.de finden Sie aktuell 6 Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 1 (SLC2A1) Proteine von 4 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen GLUT1 Antikörper (191) und GLUT1 Kits (54) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 253 GLUT1 Produkte verfügbar.
Synonyme:
0074/12, CG1086, CG13908, CG43946, Dmel\\CG43946, Dmel_CG1086, Dmel_CG13908, Dmglut1, DYT9, DYT17, DYT18, EAAT1, EIG12, GLAST, GLT1, GLU, GLUCOSE TRANSPORTER 1, GLUT, Glut-1, Glut1, GLUT1DS, GLUTB, GTG1, Gtg3, HTLVR, l(3)61Ea, l(3)L1H, l(3)S007412, PED, plastidic GLC translocator, RATGTG1, SLC2A1, T21H19.70, T21H19_70
alle Proteine anzeigen Gen GeneID UniProt
Ratte SLC2A1 SLC2A1 29483 P24942
SLC2A1 6513 P11166
SLC2A1 20525 P17809

Weitere Synonyme anzeigen

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Weitere Proteine zu GLUT1 Interaktionspartnern

Fruit Fly (Drosophila melanogaster) Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 1 (SLC2A1) Interaktionspartner

  1. Glut-1 expression globally depended on histological subtypes and the staining patterns (diffuse or zonal) were different between thymic carcinomas and type B3 thymomas

  2. Glut-1 glucose transporter expression in esophageal squamous cell carcinoma is associated with tumor aggressiveness.

  3. Glucose transporter 1 transcript levels were higher in the right ventricle than the left ventricle.

Arabidopsis thaliana Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 1 (SLC2A1) Interaktionspartner

  1. pGlcT, together with MEX1, contributes significantly to the export of starch degradation products from chloroplasts in A. thaliana leaves and and that this starch-mediated pathway for photoassimilate export via pGlcT and MEX1 is essential for the growth and development of A. thaliana. [pGlcT]

Human Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 1 (SLC2A1) Interaktionspartner

  1. These findings indicate that hyperglycemia is associated with poor survival. The putative biological mechanism might involve differential GLUT1 expression between hyperglycemic and normal states in patients with PCNSL.

  2. AKT (zeige AKT1 Proteine) inhibition blocks miR (zeige MLXIP Proteine)-124 silencing-induced AKT1 (zeige AKT1 Proteine)/2, glucose transporter 1, hexokinase II activation, cell proliferation, and glycolytic or energy metabolism changes. In summary, this study demonstrated that miR (zeige MLXIP Proteine)-124 is able to inhibit proliferation, glycolysis, and energy metabolism, potentially by targeting AKT1 (zeige AKT1 Proteine)/2-glucose transporter 1/hexokinase II in non-small cell lung cancer cells.

  3. interfering GLUT1 expression dampens IL-33 (zeige IL33 Proteine)-enhanced glucose uptake and glycolysis in NSCLC cells, thereby abrogates IL-33 (zeige IL33 Proteine)-induced NSCLC outgrowth and metastasis

  4. Here the authors report that activation of mTORC1 by Epstein-Barr virus LMP1 (zeige PDLIM7 Proteine) is a key modulator for activation of NF-kappaB (zeige NFKB1 Proteine) signaling to mediate aerobic glycolysis via Glut-1 upregulation.

  5. In oral squamous cell carcinoma , GLUT-1 expression increased with the degree of dysplasia and increasing grade.

  6. Interaction between Escherichia coli K1 OmpA and Ecgp96 downregulates peroxisome proliferator-activated receptor gamma (PPAR-gamma (zeige PPARG Proteine)) and glucose transporter 1 (GLUT-1) levels in human brain microvascular endothelial cells, causing disruption of barrier integrity and inhibition of glucose uptake.

  7. Low CSF (zeige CSF2 Proteine) glucose levels may be associated with pathogenic SLC2A1 mutations including deep intronic SLC2A1 variants in GLUT1 deficiency.

  8. Study provides evidence that overexpression of FOXM1 (zeige FOXM1 Proteine) and GLUT1 may play critical roles in hepatocellular carcinoma (HCC (zeige FAM126A Proteine)). FOXM1 (zeige FOXM1 Proteine) promotes HCC (zeige FAM126A Proteine) glycolysis by transactivating GLUT1 expression.

  9. GLUT-1 overexpression could be related to aggressiveness in ameloblastomas and ameloblastic carcinomas and must represent a normal metabolite in tooth germs

  10. We silenced Glut1 in triple-negative breast-cancer cell lines using a short hairpin RNA (shRNA) system. Knockdown of Glut1 resulted in decreased cell proliferation, glucose uptake, migration, and invasion through modulation of the EGFR (zeige EGFR Proteine)/MAPK (zeige MAPK1 Proteine) signaling pathway and integrin 1/Src (zeige SRC Proteine)/FAK (zeige PTK2 Proteine) signaling pathways. These results suggest that Glut1 also acts as a regulator of signaling cascades in the tumorigenesis of breast cancer.

Mouse (Murine) Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 1 (SLC2A1) Interaktionspartner

  1. Data (including data from studies using transgenic mice) suggest that Glut1 (glucose transporter type 1) is a critical downstream target of Hif1a (hypoxia-inducible factor 1 (zeige HIF1A Proteine), alpha subunit (zeige POLG Proteine)) mediating hyperglycemia-induced extracellular matrix accumulation in kidney via regulation of Nox4 (zeige NOX4 Proteine) (NADPH oxidase (zeige NOX1 Proteine) type 4) expression in nephropathy due to diabetes type 1.

  2. CRISPR/Cas9-mediated disruption of the Hdac2 gene increased Slc2a1 expression, suggesting that it is one of the responsible histone deacetylases (HDACs). These results confirm that b-OHB is a HDAC inhibitor and show that b-OHB plays an important role in fasting-induced epigenetic activation of a glucose transporter gene in the brain.

  3. Taken together, the data suggest that curcumin binds directly to GLUT1 at a site that overlaps with the cytochalasin B binding site and thereby inhibits glucose transport.

  4. overnutrition during early life induces short-term metabolic disturbances, impairment in heart insulin (zeige INS Proteine) signaling, up-regulates GLUT-1 (zeige SLC1A3 Proteine) and switch cardiac fuel preference in juvenile mice

  5. alpha(1)-AR activation is anti-apoptotic and protective during cardiac ischemia due to glucose deprivation and not hypoxia by enhancing glucose uptake into the heart via PKCdelta (zeige PKCd Proteine)-mediated GLUT (zeige SLC1A3 Proteine) translocation that may be specific to the alpha(1A)-AR subtype.

  6. Glut1 connects the enhanced glucose uptake in atheromatous plaques of ApoE (zeige APOE Proteine)(-/-) mice with their myelopoiesis through regulation of hematopoietic stem and multipotential progenitor cell maintenance and myelomonocytic fate.

  7. Enhanced GLUT1 expression in melanoma cells favors their metastatic behavior.

  8. bright-field microscopy designed to automatically identify and segment microvessels containing the protein glucose transporter 1.

  9. Morphological changes and GLUT1, GLUT3 (zeige SLC2A3 Proteine), and GLUT4 (zeige SLC2A4 Proteine) expression were evaluated in placentas by immunohistochemical and image analysis and correlated with iAs and arsenical species concentration, which were quantified by atomic absorption spectroscopy

  10. Nicotine pre-exposure reduced the ischemic-reperfusion-enhanced glucose transporter-1 function and expression at the blood brain barrier in a focal brain ischemia mouse model.

Cow (Bovine) Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 1 (SLC2A1) Interaktionspartner

  1. Low GLUT1 and GLUT3 (zeige SLC2A3 Proteine) expression in nonclassical monocytes was unaltered during differentiation into macrophages. GLUT4 (zeige SLC2A4 Proteine) mRNA was only detectable in unstimulated macrophages. Neither monocytes nor macrophages were insulin (zeige INS Proteine) responsive.

  2. the different conformations of the GLUT-1 transporter in luminal (blood facing) and abluminal (brain facing) membranes of bovine cerebral endothelial cells arise from differential phosphorylation of GLUT-1

  3. Significant increases in GLUT1 gene expression were observed during early lactation.

  4. Hyperthermia-induced Hsp90 (zeige HSP90 Proteine).eNOS (zeige NOS3 Proteine) preserves mitochondrial respiration in hyperglycemic endothelial cells by down-regulating Glut-1 and up-regulating G6PD (zeige G6PD Proteine) activity.

  5. distinct domains of the glucose transporter GLUT1 mediate HTLV envelope binding and virus entry

GLUT1 (SLC2A1) Protein Überblick

Protein Überblick

This gene encodes a major glucose transporter in the mammalian blood-brain barrier. The encoded protein is found primarily in the cell membrane and on the cell surface, where it can also function as a receptor for human T-cell leukemia virus (HTLV) I and II. Mutations in this gene have been found in a family with paroxysmal exertion-induced dyskinesia.

Alternative names and synonyms associated with GLUT1 (SLC2A1)

  • Glucose transporter 1 (Glut1)
  • solute carrier family 2 (facilitated glucose transporter), member 1 (SLC2A1)
  • plastidic glucose transporter (PGLCT)
  • glucose transporter type 1 (GLUT-1)
  • solute carrier family 1 (glial high affinity glutamate transporter), member 3 (Slc1a3)
  • solute carrier family 2 (facilitated glucose transporter), member 1 (Slc2a1)
  • solute carrier family 2, facilitated glucose transporter member 1-like (LOC100738195)
  • 0074/12 Protein
  • CG1086 Protein
  • CG13908 Protein
  • CG43946 Protein
  • Dmel\\CG43946 Protein
  • Dmel_CG1086 Protein
  • Dmel_CG13908 Protein
  • Dmglut1 Protein
  • DYT9 Protein
  • DYT17 Protein
  • DYT18 Protein
  • EAAT1 Protein
  • EIG12 Protein
  • GLAST Protein
  • GLT1 Protein
  • GLU Protein
  • GLUCOSE TRANSPORTER 1 Protein
  • GLUT Protein
  • Glut-1 Protein
  • Glut1 Protein
  • GLUT1DS Protein
  • GLUTB Protein
  • GTG1 Protein
  • Gtg3 Protein
  • HTLVR Protein
  • l(3)61Ea Protein
  • l(3)L1H Protein
  • l(3)S007412 Protein
  • PED Protein
  • plastidic GLC translocator Protein
  • RATGTG1 Protein
  • SLC2A1 Protein
  • T21H19.70 Protein
  • T21H19_70 Protein

Bezeichner auf Proteinebene für SLC2A1

CG43946-PB , CG43946-PC , CG43946-PD , CG43946-PE , CG43946-PJ , CG43946-PL , CG43946-PM , CG43946-PO , CG43946-PP , CG43946-PQ , CG43946-PR , CG43946-PS , CG43946-PT , CG43946-PU , CG43946-PV , CG43946-PW , CG43946-PX , Glut1-PB , Glut1-PC , Glut1-PD , Glut1-PE , Glut1-PJ , Glut1-PL , Glut1-PM , Glut1-PO , Glut1-PP , Glut1-PQ , Glut1-PR , Glut1-PS , Glut1-PT , Glut1-PU , Glut1-PV , Glut1-PW , Glut1-PX , glucose transporter , glucose transporter 1 , lethal (3) S007412 , solute carrier family 2 (facilitated glucose transporter), member 1 , solute carrier family 2, facilitated glucose transporter member 1 , solute carrier family 2 member 1 , Solute carrier family 2, facilitated glucose transporter member 1 , GLAST-1 , excitatory amino acid transporter 1 , glial glutamate transporter , glutamate transporter , glutamate/aspartate transporter , sodium-dependent glutamate/aspartate transporter 1 , solute carrier family 1, member 3 , GLUT-1 , glucose transporter type 1, erythrocyte/brain , hepG2 glucose transporter , human T-cell leukemia virus (I and II) receptor , Solute carrier family 2 a 1 (facilitated glucose transporter) brain , solute carrier family 2, member 1 , GT1 , glucose transporter protein , glucose transporter type 1 , glucose transport protein

GENE ID SPEZIES
38109 Drosophila melanogaster
482437 Canis lupus familiaris
698931 Macaca mulatta
831472 Arabidopsis thaliana
100173447 Pongo abelii
100381181 Papio anubis
443461 Ovis aries
29483 Rattus norvegicus
6513 Homo sapiens
24778 Rattus norvegicus
20525 Mus musculus
282356 Bos taurus
100125988 Oryctolagus cuniculus
396130 Gallus gallus
397404 Sus scrofa
100738195 Sus scrofa
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