DIAPH1 (DIAPH1) ELISA Kits

Bezeichnung:
Diaphanous Homolog 1 (Drosophila) ELISA Kits (DIAPH1)
Auf www.antikoerper-online.de finden Sie aktuell 4 Diaphanous Homolog 1 (Drosophila) (DIAPH1) ELISA Kits von 3 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen DIAPH1 Antikörper (67) und DIAPH1 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 85 DIAPH1 Produkte verfügbar.
Synonyme:
D18Wsu154e, DFNA1, DIA1, Diap1, Diaph1, DIAPH2, DRF1, hDIA1, LFHL1, mKIAA4062, p140mDia
list all ELISA KIts Gen GeneID UniProt
Ratte DIAPH1 DIAPH1 307483  
Maus DIAPH1 DIAPH1 13367 O08808
DIAPH1 1729 O60610

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DIAPH1 (DIAPH1) ELISA Kits nach Reaktivitäten

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Weitere ELISA Kits für DIAPH1 Interaktionspartner

Mouse (Murine) Diaphanous Homolog 1 (Drosophila) (DIAPH1) Interaktionspartner

  1. these results uncover a novel role for mDia1 in Abeta-mediated synaptotoxicity and demonstrate that inhibition of MT dynamics and accumulation of PTMs are driving factors for the induction of tau-mediated neuronal damage.

  2. Small Molecule Inhibition of Ligand-Stimulated RAGE (zeige AGER ELISA Kits)-DIAPH1 Signal Transduction.

  3. Diaphanous-related formin (zeige DIAPH3 ELISA Kits) signaling plays a role in heart and vascular development and the maintenance of SMC (zeige DYM ELISA Kits) phenotype.

  4. Liprin-alpha3 (zeige PPFIA3 ELISA Kits) uses an alpha-helical region to bind to mDia1, counteracting mouse Dia1 (zeige CYB5R3 ELISA Kits) activation by RhoA (zeige RHOA ELISA Kits).

  5. Depleting FMNL1 (zeige FMNL1 ELISA Kits), another Formin (zeige FMN1 ELISA Kits) family member, resulted in reduced mDia1 expression, while RhoA (zeige RHOA ELISA Kits) inhibition did not alter mDia1 expression, which indicated that there was a FMNL1 (zeige FMNL1 ELISA Kits)-mDia1-Profilin1 (zeige PFN1 ELISA Kits) signaling pathway in mouse oocytes.

  6. Mechanistically, mDia1 deficiency led to a downregulation of membrane-associated genes and a specific upregulation of CD14 (zeige CD14 ELISA Kits) messenger RNA in granulocytes, but not in other lineages.

  7. Mammalian diaphanous-related formin 1 regulates GSK3beta (zeige GSK3b ELISA Kits)-dependent microtubule dynamics required for T cell migratory polarization.

  8. mDia1 can efficiently put actin filaments under mechanical tension.

  9. The active form of mDia1 localized to the apical membrane in exocrine pancreas cells; introduction of an active form of mDia1 leads to a marked increase in actin bundle density along the secretory vesicle lumen perimeter.

  10. Dia1 (zeige CYB5R3 ELISA Kits) and Dia2 (zeige DIAPH3 ELISA Kits) are dynamic components of meiotic spindle and pole complex during meiotic maturation of oocytes.

Human Diaphanous Homolog 1 (Drosophila) (DIAPH1) Interaktionspartner

  1. Ligand-induced association of RAGE (zeige AGER ELISA Kits) homodimers on the cell surface increases the molecular dimension of the receptor, recruiting DIAPH1 and activating signaling pathways.

  2. The authors describe a novel patient-derived DIAPH1 mutation (c.3610C>T) in two unrelated families, which results in early termination prior to a basic amino acid motif (RRKR(1204-1207)) at the DAD C-terminus. The mutant DIA1 (zeige CYB5R3 ELISA Kits)(R1204X) disrupted the autoinhibitory DID-DAD interaction and was constitutively active.

  3. The description of a novel disorder of platelet formation and hearing loss extends the repertoire of DIAPH1-related disease, and provides new insight into the autoregulation of DIAPH1 activity.

  4. Studies indicate that diaphanous related formin 1 (DIAPH1) is essentially involved in microtubules (MTs (zeige TIMM8A ELISA Kits))-dependent early adhesion of colon cancer cells.

  5. A 51-year-old patient in a Korean family with ADNSHL was examined by pure-tone audiometry, and genetic analysis of DIAPH1 was performed. A novel variant, p.I530S (c.1589T > G), was identified in the DIAPH1 gene, and the mutation was located in the highly conserved coiled-coil domain of the DIA1 (zeige CYB5R3 ELISA Kits) protein.

  6. mDia1 is an important regulator of breast cancer cell invasion and that its effects may be mediated by MMP-2 (zeige MMP2 ELISA Kits) activity.

  7. Findings suggest that regulation of cellular trafficking and microtubule-mediated localization of MT1-MMP (zeige MMP14 ELISA Kits) by mDia1 is likely important in breast cancer invasion through the expression of cancer stem cell genes.

  8. Loss-of-function variants in DIAPH1 is associated with syndromic microcephaly, blindness, and early onset seizures.

  9. functional complementation experiments and optogenetics to show that mDia1 cooperates with the Arp2 (zeige ACTR2 ELISA Kits)/3 complex in initiating lamellipodia and ruffles.

  10. Capping protein and dia1 (zeige CYB5R3 ELISA Kits) functionally coregulate filament barbed-end assembly.

DIAPH1 Antigen-Profil

Beschreibung des Gens

This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Alternative names and synonyms associated with DIAPH1

  • diaphanous homolog 1 (Drosophila) (DIAPH1) Elisa Kit
  • diaphanous-related formin 1 (DIAPH1) Elisa Kit
  • diaphanous-related formin 1 (diaph1) Elisa Kit
  • diaphanous-related formin 1 (Diaph1) Elisa Kit
  • diaphanous homolog 1 (Drosophila) (diaph1) Elisa Kit
  • diaphanous homolog 1 (Drosophila) (Diap1) Elisa Kit
  • D18Wsu154e Elisa Kit
  • DFNA1 Elisa Kit
  • DIA1 Elisa Kit
  • Diap1 Elisa Kit
  • Diaph1 Elisa Kit
  • DIAPH2 Elisa Kit
  • DRF1 Elisa Kit
  • hDIA1 Elisa Kit
  • LFHL1 Elisa Kit
  • mKIAA4062 Elisa Kit
  • p140mDia Elisa Kit

Bezeichner auf Proteinebene für DIAPH1

diaphanous homolog 1 (Drosophila) , diaphanous homolog 1 , diaphanous homolog 2 , protein diaphanous homolog 1 , protein diaphanous homolog 1-like , diaphanous-related formin-1 , mDIA1

GENE ID SPEZIES
100684883 Canis lupus familiaris
700918 Macaca mulatta
786565 Bos taurus
733754 Xenopus (Silurana) tropicalis
100072186 Equus caballus
374040 Gallus gallus
307483 Rattus norvegicus
100457442 Pongo abelii
100478130 Ailuropoda melanoleuca
100562222 Anolis carolinensis
13367 Mus musculus
1729 Homo sapiens
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