COL1A1 Proteine (COL1A1)

Collagen, Type I, alpha 1 Proteine (COL1A1)
Auf finden Sie aktuell 13 Collagen, Type I, alpha 1 (COL1A1) Proteine von 6 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen COL1A1 Antikörper (175) und COL1A1 Kits (44) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 238 COL1A1 Produkte verfügbar.
Col1a-1, COL1A1, COL1A2, Cola-1, Cola1, COLIA1, MGC52532, Mov-13, Mov13, OI4
alle Proteine anzeigen Gen GeneID UniProt
COL1A1 1277 P02452
COL1A1 12842 P11087
COL1A1 29393 P02454

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Weitere Proteine zu COL1A1 Interaktionspartnern

Human Collagen, Type I, alpha 1 (COL1A1) Interaktionspartner

  1. In the individuals with a COL1A1 mutation, 70% (7/10) of those with a glycine substitution located C-terminal of p.Gly305 exhibited DGI (zeige DSG1 Proteine) in both dentitions while no individual (0/7) with a mutation N-terminal of this point exhibited DGI (zeige DSG1 Proteine) in either dentition

  2. we established a new regulatory model of COL1A1 regulation by HIF-1 (zeige HIF1A Proteine), and bring out its relationship with Sp3 transcription factor. In a fundamental level, these findings give insights in the mechanisms controlling COL1A1 gene expression.

  3. UBQLN4 (zeige UBQLN4 Proteine), APP (zeige APP Proteine), CTNNB1 (zeige CTNNB1 Proteine), SHBG (zeige SHBG Proteine), and COL1A1 might be involved in the development of nonalcoholic fatty liver disease, and are proposed as the potential markers for predicting the development of this condition

  4. Depletion of FKBP65 (zeige FKBP10 Proteine) and inhibition of FKBP65 (zeige FKBP10 Proteine) activity reduced the dimeric (active) form of LH2 (zeige PLOD2 Proteine) but did not affect the binding of monomeric (inactive) LH2 (zeige PLOD2 Proteine) to procollagen Ialpha1.

  5. COL11A1 as a highly specific biomarker of activated cancer-associated fibroblasts in epithelial cancers.

  6. miR (zeige MLXIP Proteine)-29b can reduce collagen biosynthesis during skin wound healing likely via post-transcriptional inhibition of HSP47 (zeige SERPINH1 Proteine) expression.

  7. overexpressed miR185 could inhibit hypertrophic scarring fibroblast growth, and the underlying mechanism was mediated, at least partly, through the suppression of TGFbeta1 and Col1 expression.

  8. TGFbeta (zeige TGFB1 Proteine) elevated the expression of CamK (zeige CAMK4 Proteine) IIbeta and CamK (zeige CAMK4 Proteine) IIdelta, while siRNA silencing of those two subtypes significantly reduced TGFbeta (zeige TGFB1 Proteine)-mediated expression of collagen A1 and fibronectin 1 (zeige FN1 Proteine).

  9. Femoral and tibial cartilage show a different behaviour concerning expression values for the genes Col1A1, Col2A1 (zeige COL2A1 Proteine) and Agg.

  10. COL1A2 (zeige COL1A2 Proteine) mRNA expression was significantly higher in malignant tissues from gastric cancer than in premalignant and normal tissues.

Mouse (Murine) Collagen, Type I, alpha 1 (COL1A1) Interaktionspartner

  1. Type I collagen was highly expressed in the spinal cord during the scar-forming phase and induced astrocytic scar formation via the integrin-N-cadherin (zeige CDH2 Proteine) pathway.

  2. collagen-I-mediated inhibition of proplatelet formation is specifically controlled by GPVI (zeige GP6 Proteine).

  3. miR (zeige MLXIP Proteine)-29b can reduce collagen biosynthesis during skin wound healing likely via post-transcriptional inhibition of HSP47 (zeige SERPINH1 Proteine) expression.

  4. Col1a1Jrt/+ mutant mice produce craniofacial and dental defects consistent with osteogenesis imperfecta (zeige COL1A2 Proteine) and Ehlers-Danlos syndrome

  5. the rate of collagen I degradation was increased in Poldip2 (zeige POLDIP2 Proteine)(+/-) vs. Poldip2 (zeige POLDIP2 Proteine)(+/+) MASMs. Conversely, activation of the PI3K/Akt (zeige AKT1 Proteine)/mTOR (zeige FRAP1 Proteine) signaling pathway, involved in regulation of protein synthesis, was significantly elevated in Poldip2 (zeige POLDIP2 Proteine)(+/-) MASMs as was beta1-integrin expression.

  6. Col1 expression was seen in the cartilage zone of the mandibular condyle cartilage.

  7. HRG (zeige HRG Proteine) binds to alpha2 integrin through low-affinity interactions in a heparin sulfate-independent manner, thereby blocking endothelial cells adhesion to collagen I.

  8. Calreticulin (zeige CALR Proteine) in mediates vascular smooth muscle cell responses to injury through the regulation of collagen deposition and neointima formation.

  9. Homocysteine Induces Collagen I Expression by Downregulating Histone Methyltransferase G9a (zeige EHMT2 Proteine)

  10. These data suggested that intestinal epithelial cells were injured after IM treatment through the pVHL (zeige VHL Proteine) overexpression-induced degradation of collagen I or HIF-1alpha (zeige HIF1A Proteine).

Cow (Bovine) Collagen, Type I, alpha 1 (COL1A1) Interaktionspartner

  1. These observations support a signaling network among JNKs, Smads, Snail1 (zeige SNAI1 Proteine), and cortactin (zeige CTTN Proteine) to regulate the invasion of MDA-MB-231 cells embedded in 3D collagen I, which may be targeted during screening of anti-invasion reagents.

  2. Data show that biglycan (zeige BGN Proteine), collagen type I, collagen type II, decorin (zeige DCN Proteine), and versican (zeige Vcan Proteine) were significantly affected by vibration duration, frequency, and amplitude.

  3. specific ADAMTS-2 domains cleave the aminopropeptide of fibrillar procollagens types I-III and V

  4. In advanced stage granulomas in Mycobacterium bovis-infected cattle, there was an increase in the expression of type I procollagen (zeige COL1A2 Proteine)

  5. These results demonstrate a novel and important functional role of the DDR2 (zeige DDR2 Proteine) extracellular domain that may contribute to collagen regulation via modulation of fibrillogenesis.

  6. Flow induced alpha2beta1 activation in cells on collagen, but not on fibronectin or fibrinogen. Conversely, alpha5beta1 and alphavbeta3 are activated on fibronectin and fibrinogen, but not collagen.

  7. A molecular model of collagen hydration is used to validate centrifugal dehydration force (CDF (zeige CTNNA2 Proteine)) and re-hydration isotherm (RHI) methods to measure and characterize hydration compartments on bovine tendon.

Pig (Porcine) Collagen, Type I, alpha 1 (COL1A1) Interaktionspartner

COL1A1 Protein Überblick

Protein Überblick

This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.

Alternative names and synonyms associated with COL1A1

  • collagen, type I, alpha 1 (col1a1)
  • collagen, type I, alpha 1 (COL1A1)
  • collagen 1a1 (col1a1)
  • collagen, type I, alpha 1 (Col1a1)
  • Col1a-1 Protein
  • COL1A1 Protein
  • COL1A2 Protein
  • Cola-1 Protein
  • Cola1 Protein
  • COLIA1 Protein
  • MGC52532 Protein
  • Mov-13 Protein
  • Mov13 Protein
  • OI4 Protein

Bezeichner auf Proteinebene für COL1A1

collagen, type I, alpha 1 , alpha 1 type I collagen , collagen, type I, alpha 2 , collagen type I alpha 1 , procollagen alpha 1 (I) , collagen 1a1 , alpha-1 type I collagen , collagen alpha 1 chain type I , collagen alpha-1(I) chain , collagen alpha-1(I) chain preproprotein , collagen of skin, tendon and bone, alpha-1 chain , pro-alpha-1 collagen type 1 , alpha-1 type 1 collagen , procollagen, type I, alpha 1 , alpha-1 collagen (I) , collagen alpha-1 chain , type I collagen pre-pro-alpha1(I) chain , prepro-alpha-1 collagen type I , type I collagen alpha 1 chain , type I collagen alpha1 , pro-alpha-1 type 1 collagen , collagen, type 1, alpha 1 , procollagen type I, alpha 1 , procollagen, type 1, alpha 1

380515 Xenopus laevis
443483 Ovis aries
455117 Pan troglodytes
574201 Macaca mulatta
100033877 Equus caballus
100135778 Oncorhynchus mykiss
1277 Homo sapiens
12842 Mus musculus
282187 Bos taurus
395532 Gallus gallus
403651 Canis lupus familiaris
100008952 Oryctolagus cuniculus
397571 Sus scrofa
100733209 Cavia porcellus
29393 Rattus norvegicus
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