anti-TRKB (NTRK2) Antikörper

Bezeichnung:
anti-Neurotrophic Tyrosine Kinase, Receptor, Type 2 Antikörper (NTRK2)
Auf www.antikoerper-online.de finden Sie aktuell 355 Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) Antikörper von 33 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TRKB Kits (50) und TRKB Proteine (38) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 469 TRKB Produkte verfügbar.
Synonyme:
AI848316, C030027L06Rik, GP145-TrkB, ntrk2, RATTRKB1, si:ch211-220b11.1, Tkrb, Trk-B, TrkB, trkb-b, TRKB1, trkB2, xtrkb

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Am meisten referenzierte anti-TRKB Antikörper

  1. Rat (Rattus) Monoclonal TRKB Primary Antibody für BI, FM - ABIN967745 : Armanini, McMahon, Sutherland, Shelton, Phillips: Truncated and catalytic isoforms of trkB are co-expressed in neurons of rat and mouse CNS. in The European journal of neuroscience 1995 (PubMed)
    Zeige alle 7 Referenzen für 967745

  2. Chicken Polyclonal TRKB Primary Antibody für IF, IP - ABIN223287 : Jang, Liu, Pradoldej, Tosini, Chang, Iuvone, Ye: N-acetylserotonin activates TrkB receptor in a circadian rhythm. in Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)
    Zeige alle 4 Referenzen für 223287

  3. Human Polyclonal TRKB Primary Antibody für WB - ABIN319265 : Dua, Singh, Thompson: Associative Classification of Mammograms using Weighted Rules. in Expert systems with applications 2011 (PubMed)
    Zeige alle 4 Referenzen für 319265

  4. Human Polyclonal TRKB Primary Antibody für WB - ABIN616053 : Lewis, Hunihan, Franco, Robertson, Palmer, Laurent, Balasubramanian, Li, Westphal: Identification and characterization of compounds that potentiate NT-3-mediated Trk receptor activity. in Molecular pharmacology 2006 (PubMed)
    Zeige alle 4 Referenzen für 616053

  5. Human Polyclonal TRKB Primary Antibody für IF - ABIN401582 : Woronowicz, Amith, De Vusser, Laroy, Contreras, Basta, Szewczuk: Dependence of neurotrophic factor activation of Trk tyrosine kinase receptors on cellular sialidase. in Glycobiology 2006 (PubMed)
    Zeige alle 4 Referenzen für 401582

  6. Human Polyclonal TRKB Primary Antibody für IHC, ELISA - ABIN1532221 : Nakagawara, Liu, Ikegaki, White, Yamashiro, Nycum, Biegel, Brodeur: Cloning and chromosomal localization of the human TRK-B tyrosine kinase receptor gene (NTRK2). in Genomics 1995 (PubMed)
    Zeige alle 2 Referenzen für 1532221

  7. Human Polyclonal TRKB Primary Antibody für FACS, IF (p) - ABIN725870 : Zhu, Xia, Han, Shao, Jing, Fan, Liu, Diao, Lv, Sun: Xiao Yao San Improves Depressive-Like Behavior in Rats through Modulation of ?-Arrestin 2-Mediated Pathways in Hippocampus. in Evidence-based complementary and alternative medicine : eCAM 2014 (PubMed)

  8. Human Monoclonal TRKB Primary Antibody für IHC (p), WB - ABIN410036 : Glueckert, Pritz, Roy, Dudas, Schrott-Fischer: Nanoparticle mediated drug delivery of rolipram to tyrosine kinase B positive cells in the inner ear with targeting peptides and agonistic antibodies. in Frontiers in aging neuroscience 2015 (PubMed)

  9. Human Polyclonal TRKB Primary Antibody für IHC (p), IHC - ABIN408506 : Simmons, Belichenko, Yang, Condon, Monbureau, Shamloo, Jing, Massa, Longo: A small molecule TrkB ligand reduces motor impairment and neuropathology in R6/2 and BACHD mouse models of Huntington's disease. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 (PubMed)

Weitere Antikörper gegen TRKB Interaktionspartner

Zebrafish Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) Interaktionspartner

  1. By immunohistochemistry, the localization of Neurotrophinss has been observed mainly in Purkinje cells; TrkA (zeige NTRK1 Antikörper) and TrkB-receptors in cells and fibers of granular and molecular layers. TrkC (zeige NTRK3 Antikörper) was faintly detected

  2. BDNF (zeige BDNF Antikörper)-TrkB influences the expression level of components of chemokine (zeige CCL1 Antikörper) signaling including Cxcr4b, and the generation of progenitors of mechanoreceptors, at the level of expression of Atoh1a-Atp2b1a.

  3. Light regulates the expression of the BDNF (zeige BDNF Antikörper)/TrkB2 system in the adult zebrafish retina.

Rhesus Monkey Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) Interaktionspartner

  1. Study showed that complex relationships exist between BDNF (zeige BDNF Antikörper)/TrkB gene expression and interneuron marker gene expression that appear to be dependent on the presence of testosterone at adolescence

Human Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) Interaktionspartner

  1. In the current work, we provide a global analysis of the physiological consequences of TrkB receptor activation in vitro and discuss the dynamic consequences of TrkB activation in vivo. Finally, we propose a clinically-feasible option for increasing BDNF (zeige BDNF Antikörper) expression in the hypothalamus to more readily utilize the oncolytic effects of BDNF (zeige BDNF Antikörper).

  2. ShcD (zeige SHC4 Antikörper) binds to active Ret (zeige RET Antikörper), TrkA (zeige NTRK1 Antikörper), and TrkB neurotrophic factor (zeige NTF3 Antikörper) receptors predominantly via its phosphotyrosine-binding (PTB (zeige PTBP1 Antikörper)) domain.

  3. These findings, while exploratory, indicate that the genotypes of NTRK2 and COMT (zeige COMT Antikörper) may contribute to relative risk for symptom burden during and shortly after the period of chemotherapy in women with early stage breast cancer.

  4. We demonstrated that downregulation of PHLDA1 (zeige PHLDA1 Antikörper) leads to a significant increase in expression of Aurora A (zeige AURKA Antikörper) and TRKB that are markers of poor prognosis in neuroblastoma (zeige ARHGEF16 Antikörper)

  5. The receptors, TrkB and p75 (zeige CUX1 Antikörper) are more highly expressed in deep infiltrating endometriosis than in peritoneal tissues.

  6. High expression of NTRK2 is associated with gastric cancer.

  7. Genetic variability of NTRK2, a susceptibility gene for psychiatric disorders, is related to emotional arousal and-independently-to brain white-matter properties in healthy individuals.

  8. High expression of TrkA (zeige NTRK1 Antikörper), TrkB, or TrkC (zeige NTRK3 Antikörper) was significantly associated with histopathology

  9. Results show up-regulation of TrkB and down-regulation of Runx3 (zeige RUNX3 Antikörper) and Keap1 (zeige KEAP1 Antikörper) in breast cancer cells and suggest that TrkB plays a key role in tumorigenicity and metastasis of breast cancer cells through suppression of Runx3 (zeige RUNX3 Antikörper) or Keap1 (zeige KEAP1 Antikörper).

  10. Our data revealed that anoikis-resistant ACHN (zeige LARP6 Antikörper) cells presented with tolerance to detachment-induced apoptosis, excessive proliferation and aggressive invasion, accompanied by upregulation of TrkB expression in contrast to parental cells

Mouse (Murine) Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) Interaktionspartner

  1. findings show that BDNF (zeige BDNF Antikörper)-TrkB signaling, rather than Dopamine signaling, in the Ventral Tegmental Area -Nuc (zeige SREBF2 Antikörper). Accumbens circuit is crucial for facilitating depressive-like depressive-like outcomes after Chronic Social Defeat Stress and they establish BDNF (zeige BDNF Antikörper)-TrkB signaling as a pathologic mechanism during periods of chronic stress.

  2. inhibition of Sig (zeige PICALM Antikörper)-1 R prevented cocaine-induced TrkB activation in hippocampal neurons.

  3. After spinal cord injury, astrocyte-specific TrkB knock-out mice showed reduced hyperpathic responses and improved motor coordination.

  4. Results imply that oleanolic acid ameliorates scopolamine-induced memory impairment by modulating the brain-derived neurotrophic factor (zeige BDNF Antikörper) -ERK1/2 (zeige MAPK1/3 Antikörper)-cAMP response element-binding protein pathway through tropomyosin receptor kinase (zeige NTRK1 Antikörper) B activation in mice, suggesting that oleanolic acid would be a potential therapeutic agent for the treatment of cognitive deficits.

  5. Data show that c-Jun NH2-terminal kinase (JNK (zeige MAPK8 Antikörper))-interacting protein-3 (JIP3 (zeige MAPK8IP3 Antikörper)) participates in the migration of cortical neurons during cortical development by mediating TrkB receptor axonal anterograde transport.

  6. findings reveal a spine-autonomous, autocrine signalling mechanism involving NMDAR (zeige GRIN1 Antikörper)-CaMKII (zeige CAMK2G Antikörper)-dependent BDNF (zeige BDNF Antikörper) release from stimulated dendritic spines and subsequent TrkB activation on these same spines that is crucial for structural and functional plasticity

  7. Following ethanol administration, phosphorylation of TrkB in the striatum was significantly reduced in wild-type mice.

  8. Results suggest that the therapeutic actions of atypical antidepressant drugs involve various neurocircuits, some of which, but not all, appears to involve BDNF (zeige BDNF Antikörper)/TrkB and downstream neuroplastic signaling

  9. Observations provide evidence that female-specific induction of estrogen receptor alpha (zeige ESR1 Antikörper) expression confers neuroprotection with TrkB agonist therapy via Src (zeige SRC Antikörper) family kinase activation and account for improved functional outcomes in female neonates post-hypoxia and ischemia.

  10. data suggest antidepressant effects of BDNF (zeige BDNF Antikörper)-TrkB in the NAc (zeige NLRP1 Antikörper), which could not be explained by activation of the transcription factors CREB (zeige CREB1 Antikörper) or beta-catenin (zeige CTNNB1 Antikörper). The effects TrkB has on depression-related behavior in different brain regions appear to critically depend on the targeted cell type.

Cow (Bovine) Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) Interaktionspartner

  1. These observations provided evidence that brain-derived naeurotrophic factor(BDNF (zeige BDNF Antikörper)) and its receptor (BDNF (zeige BDNF Antikörper) receptor) secreted by bovine sperm was important in regulation of insulin (zeige INS Antikörper) and leptin (zeige LEP Antikörper).

  2. Expressed in ganglionic neuron-like tumor cells, which may activate an embryonic autocrine pathwy involving bdnf (zeige BDNF Antikörper)-Trk-B

TRKB (NTRK2) Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with TRKB (NTRK2)

  • neurotrophic tyrosine kinase, receptor, type 2 (NTRK2) Antikörper
  • neurotrophic tyrosine kinase, receptor, type 2 (ntrk2-b) Antikörper
  • neurotrophic tyrosine kinase, receptor, type 2b (ntrk2b) Antikörper
  • neurotrophic tyrosine kinase, receptor, type 2 (ntrk2-a) Antikörper
  • neurotrophic tyrosine kinase, receptor, type 2 (ntrk2) Antikörper
  • neurotrophic tyrosine kinase, receptor, type 2 (Ntrk2) Antikörper
  • AI848316 Antikörper
  • C030027L06Rik Antikörper
  • GP145-TrkB Antikörper
  • ntrk2 Antikörper
  • RATTRKB1 Antikörper
  • si:ch211-220b11.1 Antikörper
  • Tkrb Antikörper
  • Trk-B Antikörper
  • TrkB Antikörper
  • trkb-b Antikörper
  • TRKB1 Antikörper
  • trkB2 Antikörper
  • xtrkb Antikörper

Bezeichner auf Proteinebene für NTRK2

neurotrophin receptor B xTrkB-alpha , BDNF/NT-3 growth factors receptor , neurotrophic tyrosine kinase, receptor, type 2 , BDNF/NT-3 growth factors receptor-like , neurotrophic tyrosine kinase receptor type 2 , trk-B , trkB tyrosine kinase , tyrosine kinase receptor , BDNF-tropomyosine receptor kinase B , tropomyosin-related kinase B , tyrosine kinase receptor B , GP145-TrkB/GP95-TrkB , neural receptor protein-tyrosine kinase (trkB) , trkB protein

GENE ID SPEZIES
100061700 Equus caballus
379266 Xenopus laevis
570240 Danio rerio
709757 Macaca mulatta
735394 Pan troglodytes
779173 Xenopus laevis
780110 Xenopus (Silurana) tropicalis
100388984 Callithrix jacchus
100441207 Pongo abelii
396157 Gallus gallus
4915 Homo sapiens
18212 Mus musculus
25054 Rattus norvegicus
484147 Canis lupus familiaris
505824 Bos taurus
100352548 Oryctolagus cuniculus
100723565 Cavia porcellus
100519209 Sus scrofa
101116015 Ovis aries
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