MDK Proteine (MDK)

Bezeichnung:
Midkine (Neurite Growth-Promoting Factor 2) Proteine (MDK)
Auf www.antikoerper-online.de finden Sie aktuell 40 Midkine (Neurite Growth-Promoting Factor 2) (MDK) Proteine von 14 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen MDK Antikörper (147) und MDK Kits (51) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 249 MDK Produkte verfügbar.
Synonyme:
ARAP, mdk, Mek, midkine, MK, MK-B, NEGF2, PTF-alpha-1, RIHB
alle Proteine anzeigen Gen GeneID UniProt
MDK 17242 P12025
MDK 81517 Q9R1S9
MDK 4192 P21741

Weitere Synonyme anzeigen

MDK Proteine (MDK) nach Spezies

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Am meisten referenzierte MDK Proteine

  1. Human MDK Protein expressed in Escherichia coli (E. coli) - ABIN666781 : Jin, Lahat, Korchin, Nguyen, Zhu, Wang, Lazar, Trent, Pollock, Lev: Midkine enhances soft-tissue sarcoma growth: a possible novel therapeutic target. in Clinical cancer research : an official journal of the American Association for Cancer Research 2008 (PubMed)
    Zeige alle 2 Referenzen für 666781

  2. Human MDK Protein expressed in Baculovirus infected Insect Cells - ABIN2002427 : Murasugi, Tohma-Aiba: Characterization of partially truncated human midkine expressed in Pichia pastoris. in Bioscience, biotechnology, and biochemistry 2002 (PubMed)

Weitere Proteine zu MDK Interaktionspartnern

Mouse (Murine) Midkine (Neurite Growth-Promoting Factor 2) (MDK) Interaktionspartner

  1. MK serves an indispensable role in the NFAT (zeige NFATC1 Proteine)-regulated activation of CD4 (zeige CD4 Proteine)(+) T cells and Th1 (zeige HAND1 Proteine) cell differentiation.

  2. Ethanol engages MDK (and ALK) signaling, which has important consequences for alcohol-induced neurotoxicity.

  3. Mdk plays a crucial role in the early inflammation phase and during the development of cartilaginous callus in the fracture healing process.

  4. This study demonistrated that a differential regulation of specific behavioural responses to ethanol by midkine.

  5. clonidine-induced analgesia was significantly enhanced in PTN (zeige PTN Proteine)-/- mice compared to MK-/- and WT+/+ mice in the tail-immersion test

  6. midkine plays a critical role in cardiac hypertrophy and remodelling.

  7. Midkine exerts a neuroprotective role against amphetamine-induced neurotoxicity in striatum.

  8. MK leads to a blockade of PAI-1 (zeige SERPINE1 Proteine), which is closely associated with the suppression of crescentic glomerulonephritis.

  9. Findings indicate a critical role for the midkine-Notch2 (zeige NOTCH2 Proteine) signaling axis in neuroblastoma (zeige ARHGEF16 Proteine) tumorigenesis, which implicates new strategies to treat neuroblastoma (zeige ARHGEF16 Proteine).

  10. This study concluded that MEK is essential for acquisition of gliogenic competence by radial progenitors and that levels of MEK activity regulate gliogenesis in the developing cortex.

Human Midkine (Neurite Growth-Promoting Factor 2) (MDK) Interaktionspartner

  1. Data suggest that mature KLK9 (kallikrein 9 (zeige KLK9 Proteine)) is a glycosylated chymotrypsin-like enzyme with strong preference for tyrosine over phenylalanine at P1 cleavage position; substrate specificity of KLK9 (zeige KLK9 Proteine) appears to extend to KLK10 (zeige KLK10 Proteine) and midkine; enzyme activity is enhanced by Mg2 (zeige MUC7 Proteine)+ and Ca2 (zeige CA2 Proteine)+, but is reversibly attenuated by Zn2+; KLK9 (zeige KLK9 Proteine) is inhibited in vitro by many naturally occurring or synthetic protease inhibitors.

  2. midkine may be a good inflammatory marker in renal transplant recipients as in other inflammatory diseases. Moreover, it seems that it is not affected by factors other than inflammation during the post-transplantation period.

  3. MDK plays an important role in non-small cell lung cancer progression and prognosis and may act as a convincing prognostic indicator for non-small cell lung cancer patients.

  4. The concentration of MDK in amniotic fluid declined with gestational age.MDK concentrations in amniotic fluid were far higher than in maternal plasma.

  5. The Circulating Levels of Selenium, Zinc, Midkine, Some Inflammatory Cytokines, and Angiogenic Factors in Mitral Chordae Tendineae Rupture.

  6. overexpression of midkine protein serves as an unfavorable prognostic biomarker in breast cancer patients

  7. our results suggest that midkine expression could be a clinically useful marker in predicting the presence of multiple lymph node metastases in BRAFV600E papillary thyroid carcinoma.

  8. PLSCR1 (zeige PLSCR1 Proteine) positively regulates hepatic carcinoma cell proliferation and migration through interacting with midkine

  9. Use hybrid-type modified chitosan derivative nanoparticles to deliver midkine-siRNA to HepG2 cells.

  10. SP1 (zeige PSG1 Proteine) directly up-regulated the expression of midkine (MDK), and the SP1 (zeige PSG1 Proteine)-MDK axis cooperated in glioma tumorigenesis.

Cow (Bovine) Midkine (Neurite Growth-Promoting Factor 2) (MDK) Interaktionspartner

  1. Data show that 9-cis-retinoic acid enhanced midkine gene expression, but not insulin-like growth factor-I (zeige IGF1 Proteine) gene expression, in cumulus-granulosa cells.

Rabbit Midkine (Neurite Growth-Promoting Factor 2) (MDK) Interaktionspartner

  1. Found that macrophages are the major source of midkine in the atherosclerotic neointima of in-stent restenosis in hypercholesterolemic rabbits.

Pig (Porcine) Midkine (Neurite Growth-Promoting Factor 2) (MDK) Interaktionspartner

  1. MK is able to maintain a proliferative PGC (zeige PGC Proteine) phenotype mediated by the suppression of DAZL (zeige DAZL Proteine) in early germ cells

MDK Protein Überblick

Protein Überblick

This gene encodes a member of a small family of secreted growth factors that binds heparin and responds to retinoic acid. The encoded protein promotes cell growth, migration, and angiogenesis, in particular during tumorigenesis. This gene has been targeted as a therapeutic for a variety of different disorders. Alternatively spliced transcript variants encoding multiple isoforms have been observed.

Alternative names and synonyms associated with MDK

  • midkine (neurite growth-promoting factor 2) (mdk-b)
  • midkine (Mdk)
  • midkine (neurite growth-promoting factor 2) (MDK)
  • midkine (neurite growth-promoting factor 2) (Mdk)
  • ARAP Protein
  • mdk Protein
  • Mek Protein
  • midkine Protein
  • MK Protein
  • MK-B Protein
  • NEGF2 Protein
  • PTF-alpha-1 Protein
  • RIHB Protein

Bezeichner auf Proteinebene für MDK

PTF-alpha-2 , X-PTF-alpha2 , midkine-B , pleiotrophic factor-alpha-2 , pleiotrophic factor-alpha2 , retinoic acid-induced differentiation factor , MK , amphiregulin-associated protein , midgestation and kidney protein , midkine , neurite outgrowth-promoting factor 2 , retinoic acid inducible factor , RI-HB , retinoic acid-induced heparin-binding protein

GENE ID SPEZIES
399256 Xenopus laevis
17242 Mus musculus
81517 Rattus norvegicus
4192 Homo sapiens
280852 Bos taurus
100008929 Oryctolagus cuniculus
100713073 Cavia porcellus
100359358 Sus scrofa
423196 Gallus gallus
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