Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Alle Spezies anzeigen
Weitere Synonyme anzeigen
Select your species
Human IGF1R ELISA Kit für Sandwich ELISA - ABIN417695
Bahhnassy, Mohanad, Shaarawy, Ismail, El-Bastawisy, Ashmawy, Zekri et al.: Transforming growth factor-β, insulin-like growth factor I/insulin-like growth factor I receptor and vascular endothelial growth factor-A: prognostic and predictive markers in triple-negative and ... in Molecular medicine reports 2015
Results show a significant over-expression of EGFR and IGF1R in adrenocortical carcinoma (ACC) tissue.
Data show that single-nucleotide polymorphisms (SNPs) of the IGF1R (rs12423791), and IGF1 (zeige IGF1 ELISA Kits) (rs2162679, rs5742612, rs35767) genes were significantly associated with tumor response to oxaliplatin, 5-fluorouracil, and leucovorin (FOLFOX).
Amla extract (Emblica officinalis, AE) decreases the gene and protein expression of IGF1R, a target of miR (zeige MLXIP ELISA Kits)-375, and SNAIL1 (zeige SNAI1 ELISA Kits), a transcription factor that represses E-cadherin (zeige CDH1 ELISA Kits) expression.
GSK1904529A, a Potent IGF-IR Inhibitor, Reverses MRP1 (zeige MDM4 ELISA Kits)-Mediated Multidrug Resistance
There is an accelerated loss of IGF1R, following loss of UBQLN1 (zeige UBQLN1 ELISA Kits) in lung adenocarcinoma cells.
data show that the GSK3B (zeige GSK3b ELISA Kits)-FOXO3 (zeige FOXO3 ELISA Kits) pathway is activated after partial hepatectomy, and this may be one of the mechanisms that lead to upregulation of hepatic IGF1R after partial hepatectomy.
selective impairment of IGF-1 (zeige IGF1 ELISA Kits)-induced DNA synthesis in lymphocytes of CDG patients through decreased gene expression and hypoglycosylation of the IGF-1 (zeige IGF1 ELISA Kits) receptor
The INSR (zeige INSR ELISA Kits) purified in n-dodecyl-beta-D-maltoside showed ligand-stimulated autophosphorylation and kinase activity, suggesting an intact transmembrane signaling mechanism.
Our findings suggest a novel mechanism by which CCE procyanidins can promote proteasome-independent degradation of nuclear Nrf2 (zeige GABPA ELISA Kits) through IGF-1R phosphorylation and cysteine protease (zeige CTSB ELISA Kits) activation.
Data suggest that, as part of DNA repair in nucleus of embryonic stem cells, IGF1R interacts with and phosphorylates PCNA at tyrosine residues 60, 133, and 250; this is followed by mono- and polyubiquitination of PCNA by RAD18 and SHPRH. (IGF1R = insulin-like growth factor 1 receptor; PCNA = proliferating cell nuclear antigen; RAD18 = E3 ubiquitin-protein ligase RAD18; SHPRH = E3 ubiquitin-protein ligase SHPRH)
A total of 1169 cows of 4 pure breeds (Polish Holstein Friesian, Montbeliarde, Jersey and Holstein Friesian) were genotyped. The T (IGF1R/e2/MspI) and G (IGF1R/e2/TaqI) alleles were found to be prevalent. 3 combinations of genotypes (TT/GG, TT/AG and CT/GG) were associated with the highest productivity (milk, protein and fat yields) among the breeds studied, as opposed to individuals carrying the worst CC/AA combination.
study determined IGFR1 and PAPP-A (zeige PAPPA ELISA Kits) expression both in follicles at different stages of development and in ovarian cysts; data indicate that animals with cystic ovarian disease (COD (zeige SNRPB ELISA Kits)) have an altered regulation of the IGF system in the ovary and thus allow postulating IGFR1 expression and PAPP-A (zeige PAPPA ELISA Kits) secretion as a modulator of IGF1 (zeige IGF1 ELISA Kits) in cattle with COD (zeige SNRPB ELISA Kits)
Results of the present study showed, for the first time, that the polymorphism in IGF1R is associated with superovulation traits, and indicated that the IGFIR gene can be used as a potential marker for donor selection.
two SNPs in the coding region of the insulin-like growth factor 1 receptor gene may have a role in growth of Angus cattle
insulin (zeige INS ELISA Kits)-like growth factor (IGF) receptor glycosylation is critical to the maintenance of vascular smooth muscle phenotype in the presence of factors promoting osteogenic differentiation and mineralization
The objective of this study was to estimate the allele and genotype frequencies of the IGF-IR/TaqI, m-calpain (zeige CAPN2 ELISA Kits)/HhaI, and UCP-3 (zeige UCP3 ELISA Kits)/BglI polymorphisms and to determine association between these polymorphisms and growth traits in Chinese indigenous cattle breed.
Data describes the long-term changes to skeletal muscle growth and IGF1 (zeige IGF1 ELISA Kits), 2, 1R, and 2R mRNA expression in progeny after exposure to high and low levels of maternal nutrient intake during the first two trimesters of gestation in the bovine.
Results do not support the premise that increased apoptosis associated with high levels of IGF1 (zeige IGF1 ELISA Kits) is mediated via downregulation of the IGF1R as previously found in preimplantation mouse embryos.
IGF-I (zeige IGF1 ELISA Kits) down-regulated functional IGF-I receptor via GSK-3beta (zeige GSK3b ELISA Kits) inhibition and mTOR (zeige FRAP1 ELISA Kits) activation; constitutive activity of GSK-3beta (zeige GSK3b ELISA Kits) maintained IGF-I receptor level in nonstimulated cells.
IGF-1 (zeige IGF1 ELISA Kits) and IGF-1r gene polymorphisms in East Anatolian Red and South Anatolian Red cattle breeds.
IGF-I (zeige IGF1 ELISA Kits), IGF-II, and IGFBP-3 (zeige IGFBP3 ELISA Kits) mRNA were positively correlated with IGF-IR from 50E to 180D, suggesting that the expression of IGF-system genes exhibits specific developmental patterns in the skeletal muscle tissues.
IL-1beta (zeige IL1B ELISA Kits) impaired the actions of IGF-I (zeige IGF1 ELISA Kits) at a point distal to the IGF receptor
IGF-1R is expressed in porcine somatostatin (zeige SST ELISA Kits)-containing islet D-cells
This study suggests an association between the affinity of insulin (zeige INS ELISA Kits) receptors and number of IGF-1 (zeige IGF1 ELISA Kits) receptors with placental and/or fetal growth.
mRNA expression of IGF-I receptor
This study found that expressions of Cav3.2 (zeige CACNA1H ELISA Kits) and IGF-1R, and their colocalization were not increased in DRGs of mice following axotomy. In addition, Cav3.2 (zeige CACNA1H ELISA Kits) or IGF-1R subpopulation neurons did not acquire significant switch in expression phenotype after sciatic nerve axotomy.
The present observations indicate that IGF-IR regulates glucose transporter 1 (zeige SLC2A1 ELISA Kits) activity in astrocytes.
Epithelial IGF1R is dispensable for IGF2-mediated enhanced intestinal adaptation after small bowel resection in retinoblastoma-deficient mice.
these data suggest that the decreased mammary gland tumor latency time caused by chronic IGF1R activation is related to modulation of tumor progression rather than increased tumor initiation.
Data show that tumors lacking PSMA (zeige FOLH1 ELISA Kits) had less than half the abundance of type 1 insulin (zeige INS ELISA Kits)-like growth factor receptor (zeige RYK ELISA Kits) (IGF-1R), less activity in the survival pathway mediated by PI3K-AKT (zeige AKT1 ELISA Kits) signaling, and more activity in the proliferative pathway mediated by MAPK (zeige MAPK1 ELISA Kits)-ERK1/2 (zeige MAPK1/3 ELISA Kits) signaling.
let-7g regulates autophagy in mouse granulosa cells by targeting insulin-like growth factor 1 receptor and downregulating protein kinase B (zeige AKT1 ELISA Kits)/mammalian target of rapamycin (zeige FRAP1 ELISA Kits) signaling
VEGF (zeige VEGFA ELISA Kits) and IGF1 (zeige IGF1 ELISA Kits) were critical factors for the spontaneous cardiac differentiation of BATDCs, and MEK (zeige MDK ELISA Kits)/ERK (zeige EPHB2 ELISA Kits) signaling was involved in the role of VEGF (zeige VEGFA ELISA Kits) and IGF1 (zeige IGF1 ELISA Kits).
miR (zeige MLXIP ELISA Kits)-223/IGF-IR signalling pathway is regulated in parallel in both the lung vasculature and the right ventricle under conditions of hypoxia induced pulmonary hypertension.
Data (including data from studies using heterozygous transgenic mice) suggest that gene expression in liver is altered in a model of inflammation of liver due to partial deficiency of Igf1 (zeige IGF1 ELISA Kits); this leads to over-expression of Igf1 (zeige IGF1 ELISA Kits) receptor, inflammation mediators, and acute-phase proteins, but under-expression of cytoskeletal proteins, extracellular matrix proteins, and tight junction proteins.
This study evaluated the expression of IGF-1 (zeige IGF1 ELISA Kits) receptor, insulin receptor (zeige INSR ELISA Kits) AND IGF-1 (zeige IGF1 ELISA Kits) in the lammelar tissue of horses with insulin (zeige INS ELISA Kits)-induced hyperinsulinemia.
The laminar cell types expressing insulin receptor (zeige INSR ELISA Kits) and/or insulin-like growth factor-1 receptor and the effect of dietary carbohydrates on their expression are reported.
Somatomedin (IGF-I (zeige IGF1 ELISA Kits)) is localized in equine spermatogenic and Leydig cells, and IGF-I receptor is present in spermatogonia, spermatocytes and Leydig cells.[IGF-I receptor]
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.
, insulin-like growth factor I receptor
, soluble IGF1R variant 1
, soluble IGF1R variant 2
, insulin-like growth factor receptor tyrosine kinase
, insulin-like growth factor-I receptor
, type 1 IGF receptor
, tyrosine kinase
, IGF-1 receptor
, insulin-like growth factor 1 receptor beta subunit
, insulin-like growth factor receptor 1
, insulin-like growth factor-1 receptor
, receptor tyrosine kinase
, insulin-like growth factor 1 receptor
, line 186
, insulin-like growth factor-1 receptor beta subunit