GDNF Proteine (GDNF)

Bezeichnung:
Glial Cell Line Derived Neurotrophic Factor Proteine (GDNF)
Auf www.antikoerper-online.de finden Sie aktuell 76 Glial Cell Line Derived Neurotrophic Factor (GDNF) Proteine von 20 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen GDNF Antikörper (159) und GDNF Kits (90) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 335 GDNF Produkte verfügbar.
Synonyme:
AI385739, ATF, ATF1, ATF2, BDPLT5, GDNF, gdnfa, HFB1-GDNF, HSCR3, QPD, u-PA, UPA, URK
alle Proteine anzeigen Gen GeneID UniProt
GDNF 5328 P00749
GDNF 25453 Q07731
GDNF 14573 P48540

Weitere Synonyme anzeigen

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Am meisten referenzierte GDNF Proteine

  1. Human GDNF Protein expressed in Escherichia coli (E. coli) - ABIN2667420 : Carnicella, Ron: GDNF--a potential target to treat addiction. in Pharmacology & therapeutics 2009 (PubMed)
    Zeige alle 5 Referenzen für 2667420

  2. Human GDNF Protein expressed in Escherichia coli (E. coli) - ABIN1686334 : Pelletier, Lagacé, St-Amour, Arsenault, Cisbani, Chabrat, Fecteau, Lévesque, Cicchetti: The morphological and molecular changes of brain cells exposed to direct current electric field stimulation. in The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2015 (PubMed)

Weitere Proteine zu GDNF Interaktionspartnern

Human Glial Cell Line Derived Neurotrophic Factor (GDNF) Interaktionspartner

  1. suggest that the low endogenous levels of uPA (zeige PRAP1 Proteine) in blood are actively regulated, and that the regulatory mechanisms are disrupted in QPD in a megakaryocyte-specific manner

  2. an intricate link between caveolin-1 (zeige CAV1 Proteine) and Src kinase (zeige CSK Proteine)-mediated cell signaling and alveolar epithelial cell apoptosis due to loss of SP-C (zeige SFTPC Proteine) expression through p53 (zeige TP53 Proteine) and uPA (zeige PRAP1 Proteine) system-mediated cross-talk, is reported.

  3. there is a decrease in epidermal GDNF and GFRalpha-1 protein expression in normal human skin with ageing

  4. In SOD1(G93A) spinal cords, we verified a strict correlation in the expression of the TNFalpha, TNFR1 and GDNF triad at different stages of disease progression. Yet, ablation of TNFR1 completely abolished GDNF rises in both SOD1(G93A) astrocytes and spinal cords, a condition that accelerated motor neuron degeneration and disease progression

  5. results show that the uPA (zeige PRAP1 Proteine)/uPAR (zeige PLAUR Proteine)/LRP1 (zeige LRP1 Proteine) system is a potential target for the development of therapeutic strategies to promote axonal recovery following a CNS injury

  6. In functional dyspepsia patients, duodenal expression of GDNF protein was significantly increased compared with controls. GDNF was localized in enteric glial cells, eosinophils, and epithelial cells.

  7. The present research concluded that aspirin suppressed prostate cancer cell invasion by reducing MMP-9 (zeige MMP9 Proteine) activity and uPA (zeige PRAP1 Proteine) expression through decreasing of IKK-beta (zeige IKBKB Proteine)-mediated NF-kappaB (zeige NFKB1 Proteine) activation, indicating that the ability of aspirin to inhibit cell invasion might be useful in the chemoprevention of metastatic prostate cancer.

  8. Suppression of miR (zeige MLXIP Proteine)-383 may increase the therapeutic potential of human bone-marrow-derived MSCs in treating spinal cord injury via augmentation of GDNF protein levels.

  9. These studies identify uPA (zeige PRAP1 Proteine)-dependent de-repression of vegfr1 (zeige FLT1 Proteine) and vegfr2 (zeige KDR Proteine) gene transcription through binding to HHEX/PRH (zeige HHEX Proteine) as a novel mechanism by which uPA (zeige PRAP1 Proteine) mediates the pro-angiogenic effects of VEGF (zeige VEGFA Proteine) and identifies a potential new target for control of pathologic angiogenesis.

  10. Our results suggest that GDNF rs3096140 might be involved in the genetic background of smoking, independent of anxiety characteristics.

Mouse (Murine) Glial Cell Line Derived Neurotrophic Factor (GDNF) Interaktionspartner

  1. identified IFNg (zeige IFNG Proteine), Neurturin (Nrtn (zeige NRTN Proteine)), and glial-derived neurotrophic factor (GDNF) as ligands with unexpected roles in promoting neurogenic differentiation (zeige NEUROD1 Proteine) of Neural Precursor Cells in vivo.

  2. Using an organ culture system for prostate development and Ret (zeige RET Proteine) mutant mice, we demonstrate that RET (zeige RET Proteine)-mediated GDNF signaling in UGS increases proliferation of mesenchyme cells and suppresses androgen-induced proliferation and differentiation of prostate epithelial cells, inhibiting prostate development.

  3. The GDNF-GFRalpha1 (zeige GFRA1 Proteine) complex is essential for proper hippocampal circuit development.

  4. In SOD1(G93A) spinal cords, we verified a strict correlation in the expression of the TNFalpha, TNFR1 and GDNF triad at different stages of disease progression. Yet, ablation of TNFR1 completely abolished GDNF rises in both SOD1(G93A) astrocytes and spinal cords, a condition that accelerated motor neuron degeneration and disease progression

  5. GDNF signals were able to induce the stratified aggregate formation of GFRalpha1 (zeige GFRA1 Proteine)-positive undifferentiated spermatogonia

  6. Our results show the existence of two subpopulations of peptidergic nociceptors characterized by the presence of CGRP (zeige CALCA Proteine), one expressing BDNF (zeige BDNF Proteine) (plus SP), the other expressing GDNF (plus SST (zeige SST Proteine)), suggesting a different role for these two neurotrophic factors in the discrimination of specific painful stimuli modalities.

  7. The data of this study suggested that short-term exposure to hyperoxic conditions can affect the regulation and expression of BDNF (zeige BDNF Proteine) potentially leading to alterations in neural development.

  8. The Gdnf cKO males sired up to two litters but became infertile due to collapse of spermatogenesis and loss of undifferentiated spermatogonia

  9. Our results reveal the role of GDNF in nigrostriatal dopamine system postnatal development and adult function, and highlight the importance of correct spatial expression of GDNF

  10. Mice overexpressing GDNF had significantly reduced P62 (zeige GTF2H1 Proteine) protein levels suggestive of accelerated autophagy. They also had reduced PPAR-gamma (zeige PPARG Proteine) and CD36 (zeige CD36 Proteine) gene expression and protein levels, and lower expression of mRNA coding for enzymes involved lipogenesis.

GDNF Protein Überblick

Protein Überblick

This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene may be associated with Hirschsprung disease.

Alternative names and synonyms associated with GDNF

  • plasminogen activator, urokinase (PLAU)
  • glial cell derived neurotrophic factor (Gdnf)
  • glial cell derived neurotrophic factor a (gdnfa)
  • glial cell derived neurotrophic factor (GDNF)
  • glial cell line derived neurotrophic factor (Gdnf)
  • glial cell derived neurotrophic factor (gdnf-a)
  • AI385739 Protein
  • ATF Protein
  • ATF1 Protein
  • ATF2 Protein
  • BDPLT5 Protein
  • GDNF Protein
  • gdnfa Protein
  • HFB1-GDNF Protein
  • HSCR3 Protein
  • QPD Protein
  • u-PA Protein
  • UPA Protein
  • URK Protein

Bezeichner auf Proteinebene für GDNF

U-plasminogen activator , plasminogen activator, urinary , urokinase-type plasminogen activator , ATF , Glial cell line derived neutrophic factor , astrocyte-derived trophic factor , glial cell line derived neurotrophic factor , glial cell line-derived neurotrophic factor , zGDNF , glial cell line-derived neurotrophic factor long form , glial cell derived neurotrophic factor , glial cell-line derived neurotrophic factor , mGDNF , neurotrophic factor , glial cell line-derived neurotrophic factor a , xGDNF , glia-derived neurotrophic growth factor

GENE ID SPEZIES
5328 Homo sapiens
25453 Rattus norvegicus
79379 Danio rerio
386587 Bos taurus
395569 Gallus gallus
471566 Pan troglodytes
489224 Canis lupus familiaris
706345 Macaca mulatta
100322894 Sus scrofa
14573 Mus musculus
779087 Xenopus laevis
2668 Homo sapiens
100067053 Equus caballus
101117619 Ovis aries
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