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anti-ERBB3 (ERBB3) Antikörper

anti-V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) Antikörper (ERBB3)
Auf finden Sie aktuell 513 V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) Antikörper von 32 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen ERBB3 Proteine (43) und ERBB3 Kits (31) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 616 ERBB3 Produkte verfügbar.
c-erbB-3, c-erbB3, C76256, Erbb-3, ERBB3, erbB3-S, Erbb3r, Her3, LCCS2, MDA-BF-1, nuc-ErbB3, p45-sErbB3, p85-sErbB3, p180-ErbB3

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Am meisten referenzierte anti-ERBB3 Antikörper

  1. Human Polyclonal ERBB3 Primary Antibody für FACS, IHC (p) - ABIN391949 : Katoh, Yazaki, Sugimura, Terada: c-erbB3 gene encodes secreted as well as transmembrane receptor tyrosine kinase. in Biochemical and biophysical research communications 1993 (PubMed)
    Zeige alle 7 Referenzen für ABIN391949

  2. Human Polyclonal ERBB3 Primary Antibody für IP, WB - ABIN117962 : Liu, Carvajal, Carraway, Carraway, Pflugfelder: Expression of the receptor tyrosine kinases, epidermal growth factor receptor, ErbB2, and ErbB3, in human ocular surface epithelia. in Cornea 2001 (PubMed)
    Zeige alle 4 Referenzen für ABIN117962

  3. Human Polyclonal ERBB3 Primary Antibody für IF, IHC (p) - ABIN319383 : Holbro, Beerli, Maurer, Koziczak, Barbas, Hynes: The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation. in Proceedings of the National Academy of Sciences of the United States of America 2003 (PubMed)
    Zeige alle 4 Referenzen für ABIN319383

  4. Human Monoclonal ERBB3 Primary Antibody für IHC (p) - ABIN1687349 : Wang, Huang, Lyu, Cai, Yang, Li, Tan, Edgerton, Thor, Lee, Liu: Therapeutic targeting of erbB3 with MM-121/SAR256212 enhances antitumor activity of paclitaxel against erbB2-overexpressing breast cancer. in Breast cancer research : BCR 2014 (PubMed)
    Zeige alle 2 Referenzen für ABIN1687349

  5. Human Monoclonal ERBB3 Primary Antibody für IHC (p) - ABIN1687359 : Huang, Wang, Lyu, Cai, Yang, Wang, Liu: The anti-erbB3 antibody MM-121/SAR256212 in combination with trastuzumab exerts potent antitumor activity against trastuzumab-resistant breast cancer cells. in Molecular cancer 2014 (PubMed)
    Zeige alle 2 Referenzen für ABIN1687359

  6. Human Monoclonal ERBB3 Primary Antibody für ICC, ELISA - ABIN969114 : Sakai, Yokote, Murakami-Murofushi, Tamura, Saijo, Nishio: Pertuzumab, a novel HER dimerization inhibitor, inhibits the growth of human lung cancer cells mediated by the HER3 signaling pathway. in Cancer science 2007 (PubMed)
    Zeige alle 2 Referenzen für ABIN969114

  7. Human Monoclonal ERBB3 Primary Antibody für EIA, FACS - ABIN119014 : Rajkumar, Gullick: A monoclonal antibody to the human c-erbB3 protein stimulates the anchorage-independent growth of breast cancer cell lines. in British journal of cancer 1994 (PubMed)

  8. Cow (Bovine) Polyclonal ERBB3 Primary Antibody für WB - ABIN782970 : van der Horst, Weber, Ullrich: Tyrosine phosphorylation of PYK2 mediates heregulin-induced glioma invasion: novel heregulin/HER3-stimulated signaling pathway in glioma. in International journal of cancer. Journal international du cancer 2004 (PubMed)

Weitere Antikörper gegen ERBB3 Interaktionspartner

Rhesus Monkey V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) Interaktionspartner

  1. Widespread expression of ErbB3 receptor mRNAs was found throughout the telencephalon of juvenile and adult monkeys with in situ hybridization.

Pig (Porcine) V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) Interaktionspartner

  1. data confirmed that an ErbB3-driven pathway mediates a net positive influence in an in vivo model closely resembling human repair

Human V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) Interaktionspartner

  1. the phosphorylation levels of ErbB2 (zeige ERBB2 Antikörper), ErbB3 and Akt (zeige AKT1 Antikörper) and the protein levels of cyclin D1 (zeige CCND1 Antikörper) were decreased by lapatinib treatment of HSC3, HSC4 and Ca9 (zeige CA9 Antikörper)-22 cells

  2. In high-grade serous ovarian carcinoma (HGSC), high HER3 mRNA expression was a favorable prognostic factor for survival, while for high HER3 protein expression, a trend towards better survival was seen. A subgroup of HGSC with negative HER3 staining and negative HER3 mRNA levels showed most unfavorable survival.

  3. ERBB3 and ERBB4 (zeige ERBB4 Antikörper) have roles in lung adenocarcinoma

  4. Results suggest that silibinin is a potential anti-cancer drug to inhibit proliferative and invasive characteristics of the epithelial ovarian cancer (EOC) cells that exhibit an autocrine heregulin (HRG (zeige NRG1 Antikörper))/HER3 protein (HRG (zeige NRG1 Antikörper)/HER3) pathway.

  5. findings suggest that HBx promotes the progression of hepatocellular carcinoma by decreasing the stability of Nrdp1 (zeige RNF41 Antikörper), which results in up-regulation of ErbB3

  6. High HER3 expression in colon cancer was associated to distal colon location and low-grade tumor.

  7. Correlate ERBB3 gene SNPs with rheumatoid arthritis susceptibility.

  8. Nrdp1S is a tumour suppressor that which potentiates the Nrdp1 (zeige RNF41 Antikörper)-mediated ubiquitination and degradation of ErbB3. An Nrdp1S deficiency may also be an important factor in the loss of Nrdp1 (zeige RNF41 Antikörper).

  9. In response to trastuzumab, both HER3 and the metalloprotease (zeige ADAM8 Antikörper) ADAM10 (zeige ADAM10 Antikörper) are simultaneously upregulated. The proteolytic activity of the latter then releases the HER3 ligand heregulin (zeige NRG1 Antikörper) from the cell surface to activate HER3 and confer resistance to trastuzumab by inducing compensatory growth factor receptor (zeige RYK Antikörper) signaling.

  10. the identification of HER3-V855A and its functional properties for the first time clearly implicates genomic HER3 activation in the pathogenesis of lung cancer.

Mouse (Murine) V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) Interaktionspartner

  1. nuc-ErbB3 directly regulates levels of H3K27me3 in Schwann cells

  2. Data indicate that Sonic hedgehog (Shh (zeige SHH Antikörper)) stimulate branching morphogenesis (BrM (zeige SMARCA2 Antikörper)) and induced synthesis of mRNAs for Ptch1 (zeige PTCH1 Antikörper) protein, epidermal growth factor (EGF (zeige EGF Antikörper)) and receptors of the ErbB (zeige EGFR Antikörper) receptors ErbB1 (zeige EGFR Antikörper), ErbB2 (zeige ERBB2 Antikörper) and ErbB3.

  3. ERBB3 is required for wound healing and for the progression of skin tumors in mice.

  4. The expression of ERBB3 in combination with ERBB4 (zeige ERBB4 Antikörper) significantly amplifies proliferation of lymphocytes upon ligand stimulation.

  5. Data indicate that increased expression of erbB3 plays a pivotal role in activating downstream PI-3K/Akt (zeige AKT1 Antikörper) pathway and promoting erbB2 (zeige ERBB2 Antikörper)-driven mammary/breast tumorigenesis.

  6. Suggest that ERBB3 may promote hepatocellular carcinoma through STAT3 (zeige STAT3 Antikörper) activation.

  7. ERBB3 is crucial for the proliferation of Bergmann glia in the developing cerebellum.

  8. ErbB3 plays a key role in migration, as well as in myelination, in mouse Schwann lineage cells.

  9. Knock-down of Erbb3 with siRNA during early differentiation inhibits cardiomyogenesis in embryonic stem cells.

  10. Myocilin (zeige MYOC Antikörper) binds to ErbB2 (zeige ERBB2 Antikörper)/ErbB3, activates these receptors, and affects the downstream PI3K-AKT (zeige AKT1 Antikörper) signaling pathway

ERBB3 Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported, but they have not been thoroughly characterized.

Alternative names and synonyms associated with ERBB3

  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) (ERBB3) Antikörper
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 (ERBB3) Antikörper
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 (Erbb3) Antikörper
  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) (Erbb3) Antikörper
  • c-erbB-3 Antikörper
  • c-erbB3 Antikörper
  • C76256 Antikörper
  • Erbb-3 Antikörper
  • ERBB3 Antikörper
  • erbB3-S Antikörper
  • Erbb3r Antikörper
  • Her3 Antikörper
  • LCCS2 Antikörper
  • MDA-BF-1 Antikörper
  • nuc-ErbB3 Antikörper
  • p45-sErbB3 Antikörper
  • p85-sErbB3 Antikörper
  • p180-ErbB3 Antikörper

Bezeichner auf Proteinebene für ERBB3

v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) , receptor tyrosine kinase ErbB3 , receptor tyrosine-protein kinase erbB-3-like , proto-oncogene-like protein c-ErbB-3 , receptor tyrosine-protein kinase erbB-3 , tyrosine kinase-type cell surface receptor HER3 , avian erythroblastosis oncogene B 3 , c-erbB-3 , c-erbB3 , v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 , avian erythroblastosis oncogene B 3 receptor , glial growth factor receptor , receptor tyrosine kinase

481105 Canis lupus familiaris
711407 Macaca mulatta
100008807 Oryctolagus cuniculus
100126862 Sus scrofa
100468735 Ailuropoda melanoleuca
2065 Homo sapiens
29496 Rattus norvegicus
13867 Mus musculus
Ausgewählte Anbieter für anti-ERBB3 (ERBB3) Antikörper
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