anti-ERBB3 (ERBB3) Antikörper

Bezeichnung:
anti-V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) Antikörper (ERBB3)
Auf www.antikoerper-online.de finden Sie aktuell 546 V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) Antikörper von 32 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen ERBB3 Proteine (44) und ERBB3 Kits (37) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 657 ERBB3 Produkte verfügbar.
Synonyme:
c-erbB-3, c-erbB3, C76256, Erbb-3, ERBB3, erbB3-S, Erbb3r, Her3, LCCS2, MDA-BF-1, nuc-ErbB3, p45-sErbB3, p85-sErbB3, p180-ErbB3

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Am meisten referenzierte anti-ERBB3 Antikörper

  1. Human Polyclonal ERBB3 Primary Antibody für FACS, IHC (p) - ABIN391949 : Katoh, Yazaki, Sugimura, Terada: c-erbB3 gene encodes secreted as well as transmembrane receptor tyrosine kinase. in Biochemical and biophysical research communications 1993 (PubMed)
    Zeige alle 7 Referenzen für 391949

  2. Human Monoclonal ERBB3 Primary Antibody für FACS - ABIN4896267 : MacLeod, Elgadi, Bossi, Sankar, Pisio, Agopsowicz, Sharon, Graham, Hitt: HER3 targeting of adenovirus by fiber modification increases infection of breast cancer cells in vitro, but not following intratumoral injection in mice. in Cancer gene therapy 2012 (PubMed)
    Zeige alle 5 Referenzen für 4896267

  3. Human Monoclonal ERBB3 Primary Antibody für ELISA (Capture), FACS - ABIN4899526 : Liu, Leng, Gunasekaran, Pentony, Shen, Howard, Stoops, Manchulenko, Razinkov, Liu, Fanslow, Hu, Sun, Hasegawa, Clark, Foltz, Yan: A Novel Antibody Engineering Strategy for Making Monovalent Bispecific Heterodimeric IgG Antibodies by Electrostatic Steering Mechanism. in The Journal of biological chemistry 2015 (PubMed)
    Zeige alle 5 Referenzen für 4899526

  4. Human Polyclonal ERBB3 Primary Antibody für IF, IHC (p) - ABIN319383 : Holbro, Beerli, Maurer, Koziczak, Barbas, Hynes: The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation. in Proceedings of the National Academy of Sciences of the United States of America 2003 (PubMed)
    Zeige alle 4 Referenzen für 319383

  5. Human Monoclonal ERBB3 Primary Antibody für IHC (p) - ABIN1687349 : Wang, Huang, Lyu, Cai, Yang, Li, Tan, Edgerton, Thor, Lee, Liu: Therapeutic targeting of erbB3 with MM-121/SAR256212 enhances antitumor activity of paclitaxel against erbB2-overexpressing breast cancer. in Breast cancer research : BCR 2014 (PubMed)
    Zeige alle 2 Referenzen für 1687349

  6. Human Monoclonal ERBB3 Primary Antibody für IHC (p) - ABIN1687359 : Huang, Wang, Lyu, Cai, Yang, Wang, Liu: The anti-erbB3 antibody MM-121/SAR256212 in combination with trastuzumab exerts potent antitumor activity against trastuzumab-resistant breast cancer cells. in Molecular cancer 2014 (PubMed)
    Zeige alle 2 Referenzen für 1687359

  7. Human Monoclonal ERBB3 Primary Antibody für FACS - ABIN4896259 : Sie, den Dunnen, Lourens, Meeuwsen-de Boer, Scherpen, Zomerman, Kampen, Hoving, de Bont: Growth-factor-driven rescue to receptor tyrosine kinase (RTK) inhibitors through Akt and Erk phosphorylation in pediatric low grade astrocytoma and ependymoma. in PLoS ONE 2015 (PubMed)

  8. Human Monoclonal ERBB3 Primary Antibody für EIA, FACS - ABIN119014 : Rajkumar, Gullick: A monoclonal antibody to the human c-erbB3 protein stimulates the anchorage-independent growth of breast cancer cell lines. in British journal of cancer 1994 (PubMed)

  9. Human Polyclonal ERBB3 Primary Antibody für ELISA, WB - ABIN185461 : van der Horst, Weber, Ullrich: Tyrosine phosphorylation of PYK2 mediates heregulin-induced glioma invasion: novel heregulin/HER3-stimulated signaling pathway in glioma. in International journal of cancer. Journal international du cancer 2004 (PubMed)

Weitere Antikörper gegen ERBB3 Interaktionspartner

Rhesus Monkey V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) Interaktionspartner

  1. Widespread expression of ErbB3 receptor mRNAs was found throughout the telencephalon of juvenile and adult monkeys with in situ hybridization.

Pig (Porcine) V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) Interaktionspartner

  1. data confirmed that an ErbB3-driven pathway mediates a net positive influence in an in vivo model closely resembling human repair

Human V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) Interaktionspartner

  1. Pretreatment with the soluble ErbB3 N418Q mutant suppressed heregulin (zeige NRG1 Antikörper) beta1-induced HIF-1alpha (zeige HIF1A Antikörper) activation in MCF7 cells.

  2. we show that WASF3 (zeige WASF3 Antikörper) is present in the HER2 (zeige ERBB2 Antikörper) immunocomplex and suppression of WASF3 (zeige WASF3 Antikörper) function leads to suppression of invasion even in the presence of HER2 (zeige ERBB2 Antikörper) expression.The engagement of WASF3 (zeige WASF3 Antikörper) with the HER2 (zeige ERBB2 Antikörper)/HER3 complex facilitates its phospho-activation and transcriptional upregulation, which is facilitated by HER2 (zeige ERBB2 Antikörper)/HER3 activation of JAK (zeige JAK3 Antikörper)/STAT (zeige STAT1 Antikörper) signaling.

  3. This study demonstrates novel regulatory circuits involving miR (zeige MLXIP Antikörper)-148a-3p/ERBB3/AKT2 (zeige AKT2 Antikörper)/c-myc (zeige MYC Antikörper) and DNMT1 (zeige DNMT1 Antikörper) that controls bladder cancer progression, which may be useful in the development of more effective therapies against bladder cancer.

  4. HRG (zeige NRG1 Antikörper)/HER2 (zeige ERBB2 Antikörper)/HER3 signaling promotes AhR (zeige AHR Antikörper)-mediated Memo-1 (zeige MEMO1 Antikörper) expression and migration in colorectal cancer

  5. Simultaneous suppression of ErbB (zeige EGFR Antikörper) kinases and androgen signaling by Celecoxib represents a novel strategy to interrupt the vicious cycle of AR/ErbB (zeige EGFR Antikörper) cross-talk with the primary purpose of undermining their resilient signaling in prostate cancer progression.

  6. Targeting both HER2 (zeige ERBB2 Antikörper) and HER3 resulted in an improved treatment effects on HER2 (zeige ERBB2 Antikörper)-positive gastric cancer.

  7. HER3 is frequently overexpressed in high-grade dysplastic lesions of the gastroesophageal junction and may be a marker of invasive progression

  8. the mechanistic regulation and linkage of the ROR1 (zeige ROR1 Antikörper)-HER3 and Hippo-YAP (zeige YAP1 Antikörper) pathway in a cancer-specific context

  9. There were significant differences in human epidermal growth factor receptor (zeige EGFR Antikörper) 2 and human epidermal growth factor receptor (zeige EGFR Antikörper) 3 serum levels between the patients with tissue human epidermal growth factor receptor (zeige EGFR Antikörper) 2-positive and tissue human epidermal growth factor receptor (zeige EGFR Antikörper) 2-negative ( p = 0.0026, p = 0.000011) tumors, but not in the serum levels of human epidermal growth factor receptor (zeige EGFR Antikörper) 4 ( p = 0.054).

  10. Results from circular dichroism spectroscopy, size exclusion chromatography with multiangle light scattering, dynamic light scattering, analytical ultracentrifugation, and small angle X-ray scattering each provide evidence that the EGFR (zeige EGFR Antikörper) and HER3 C-terminal tails are intrinsically disordered with extended, non-globular structure in solution.

Mouse (Murine) V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) Interaktionspartner

  1. Our results support a role for the hepatocellular ERBB (zeige EGFR Antikörper) tyrosine kinases in fibrogenesis. Maximal impact to fibrogenesis occurred in the ERBB3 and EGFR (zeige EGFR Antikörper)-ERBB3 DKO models, suggesting that EGFR (zeige EGFR Antikörper)-ERBB3 heterodimeric signaling in damaged hepatocytes may play a more important role in liver fibrosis than EGFR-EGFR (zeige EGFR Antikörper) homodimeric signaling.

  2. nuc-ErbB3 directly regulates levels of H3K27me3 in Schwann cells

  3. Data indicate that Sonic hedgehog (Shh (zeige SHH Antikörper)) stimulate branching morphogenesis (BrM (zeige SMARCA2 Antikörper)) and induced synthesis of mRNAs for Ptch1 (zeige PTCH1 Antikörper) protein, epidermal growth factor (EGF (zeige EGF Antikörper)) and receptors of the ErbB (zeige EGFR Antikörper) receptors ErbB1 (zeige EGFR Antikörper), ErbB2 (zeige ERBB2 Antikörper) and ErbB3.

  4. ERBB3 is required for wound healing and for the progression of skin tumors in mice.

  5. The expression of ERBB3 in combination with ERBB4 (zeige ERBB4 Antikörper) significantly amplifies proliferation of lymphocytes upon ligand stimulation.

  6. Data indicate that increased expression of erbB3 plays a pivotal role in activating downstream PI-3K/Akt (zeige AKT1 Antikörper) pathway and promoting erbB2 (zeige ERBB2 Antikörper)-driven mammary/breast tumorigenesis.

  7. Suggest that ERBB3 may promote hepatocellular carcinoma through STAT3 (zeige STAT3 Antikörper) activation.

  8. ERBB3 is crucial for the proliferation of Bergmann glia in the developing cerebellum.

  9. ErbB3 plays a key role in migration, as well as in myelination, in mouse Schwann lineage cells.

  10. Knock-down of Erbb3 with siRNA during early differentiation inhibits cardiomyogenesis in embryonic stem cells.

ERBB3 Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported, but they have not been thoroughly characterized.

Alternative names and synonyms associated with ERBB3

  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) (ERBB3) Antikörper
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 (ERBB3) Antikörper
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 (Erbb3) Antikörper
  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) (Erbb3) Antikörper
  • c-erbB-3 Antikörper
  • c-erbB3 Antikörper
  • C76256 Antikörper
  • Erbb-3 Antikörper
  • ERBB3 Antikörper
  • erbB3-S Antikörper
  • Erbb3r Antikörper
  • Her3 Antikörper
  • LCCS2 Antikörper
  • MDA-BF-1 Antikörper
  • nuc-ErbB3 Antikörper
  • p45-sErbB3 Antikörper
  • p85-sErbB3 Antikörper
  • p180-ErbB3 Antikörper

Bezeichner auf Proteinebene für ERBB3

v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) , receptor tyrosine kinase ErbB3 , receptor tyrosine-protein kinase erbB-3-like , proto-oncogene-like protein c-ErbB-3 , receptor tyrosine-protein kinase erbB-3 , tyrosine kinase-type cell surface receptor HER3 , avian erythroblastosis oncogene B 3 , c-erbB-3 , c-erbB3 , v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 , avian erythroblastosis oncogene B 3 receptor , glial growth factor receptor , receptor tyrosine kinase

GENE ID SPEZIES
481105 Canis lupus familiaris
711407 Macaca mulatta
100008807 Oryctolagus cuniculus
100126862 Sus scrofa
100468735 Ailuropoda melanoleuca
2065 Homo sapiens
29496 Rattus norvegicus
13867 Mus musculus
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