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Human Betacellulin ELISA Kit für Sandwich ELISA - ABIN625268
Lim, Yoo, Kim, Hur, Lee, Hur, Lee, Lee, Park, Lee, Chang, Kim, Kang, Hong, Kim, Kim, Yoon, Nam, Yang, Kim, Cho, Won: GC1118, an Anti-EGFR Antibody with a Distinct Binding Epitope and Superior Inhibitory Activity against High-Affinity EGFR Ligands. in Molecular cancer therapeutics 2016
Our results suggest that betacellulin induces ovarian cancer migration and Slug-dependent E-cadherin (zeige CDH1 ELISA Kits) down-regulation
CXCL8 (zeige IL8 ELISA Kits) production from lung cancer cells could be initiated by an autocrine mechanism or external sources of BTC.
Data suggest that BTC (betacellulin), AREG (amphiregulin (zeige AREG ELISA Kits)), and EREG (epiregulin (zeige EREG ELISA Kits)) induced prostaglandin E2 production by induction of COX-2 (prostaglandin-endoperoxide synthase 2 (zeige PTGS2 ELISA Kits)) through MAP kinase (zeige MAPK1 ELISA Kits) signaling in granulosa cells.
BTC has properties of increasing retinal vascular leakage that could contribute to the development of diabetic retinopathy.
Data suggest a novel receptor-independent role for betacellulin intracellular-domain fragment signaling due to its ability to inhibit cell growth in vitro.
These are the first data that demonstrate an influence of betacellulin upon mesenchymal stem cells and the first to implicate HIF-alpha in betacellulin-mediated proliferation.
The solution structure of the EGF (zeige EGF ELISA Kits)-like domain of betacellulin has been determined using two-dimensional nuclear magnetic resonance spectroscopy
Betacellulin and heregulin/NDF (zeige NRG1 ELISA Kits)-alpha are involved in epidermal morphogenesis and/or in maintenance of the differentiated phenotype.
although BTC and EGF share overlapping signaling properties, the ability of BTC to enhance Erk activation occurs independent of Ras.
BTC may play a pivotal role as a local growth factor in promoting the differentiated villous trophoblastic function via ErbB-1 (zeige EGFR ELISA Kits) in early placentas and in contributing to placental growth through EVT cell function via ErbB-4 (zeige ERBB4 ELISA Kits) in term placentas.
The results of this study suggested a novel regulatory role of Btc in axon-Schwann cell interactions involved in myelin formation and nerve repair.
BTC induces expansion of neural stem cells and neuroblasts, and promotes neurogenesis in the olfactory bulb and dentate gyrus.
Betacellulin exerts proliferative activity on beta cells through the activation of ErbB-1 (zeige EGFR ELISA Kits) and ErbB-2 (zeige ERBB2 ELISA Kits) receptors
BTC overexpression enhances glucose-induced insulin (zeige INS ELISA Kits) secretion in Mesenchyma Stem Cells
Betacellulin protects from pancreatitis by activating stress-activated protein kinase.
Excess of betacellulin exerts no deleterious effects on the structure or function of the male reproductive tract in mice.
structure of the BTC gene
Defective valvulogenesis in HB-EGF and TACE-null mice is associated with aberrant BMP signaling.
epidermal growth factor (EGF (zeige EGF ELISA Kits)) family members amphiregulin (zeige AREG ELISA Kits), epiregulin (zeige EREG ELISA Kits), and beta-cellulin are paracrine mediators that propagate the LH signal throughout the ovulatory follicle
Mice overexpressing BTC exhibit high early postnatal mortality, reduced body weight gain, impaired longitudinal growth, cataract, retinal and bone abnormalities, and lung disease.
The protein encoded by this gene is a member of the EGF family of growth factors. It is synthesized primarily as a transmembrane precursor, which is then processed to mature molecule by proteolytic events. This protein is a ligand for the EGF receptor.