TDRD1 Proteine (TDRD1)

Bezeichnung:
Tudor Domain Containing 1 Proteine (TDRD1)
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Synonyme:
CT41.1, im:7155161, MTR-1
alle Proteine anzeigen Gen GeneID UniProt
TDRD1 56165 Q9BXT4
TDRD1 83561 Q99MV1
TDRD1 292129  

Weitere Synonyme anzeigen

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Weitere Proteine zu TDRD1 Interaktionspartnern

Human Tudor Domain Containing 1 (TDRD1) Interaktionspartner

  1. TDRD1 protein is expressed in the majority of human prostate tumors, but not in normal prostate tissue.

  2. the involvement of TDRD1 genetic polymorphisms in piRNA processing genes in the risk of spermatogenic impairment in a Han Chinese population

  3. ERG (zeige ERG Proteine) induces epigenetic activation of Tudor domain-containing protein 1 (TDRD1) in ERG (zeige ERG Proteine) rearrangement-positive prostate cancer.

  4. TDRD1 is the first identified upregulated direct ERG (zeige ERG Proteine) target gene that is strongly associated with ERG (zeige ERG Proteine) overexpression in primary prostate cancer

Mouse (Murine) Tudor Domain Containing 1 (TDRD1) Interaktionspartner

  1. TDRD1 can accommodate different peptides from different proteins, and can therefore act as a scaffold protein (zeige HOMER1 Proteine) for complex assembly in the piRNA pathway.

  2. Data suggest that the formation of complexes between MILI, MIWI (zeige PIWIL1 Proteine) and TDRD1/MTR-1 is critical for the integrated subcellular localizations of these proteins, and is presumably essential for spermatogenesis.

  3. isolated Mouse tudor repeat-1 (Mtr-1) which encodes a MYND domain and four copies of the tudor domain. Mtr-1 is expressed in germ-line cells and is most abundant in fetal prospermatogonia and postnatal primary spermatocytes.

  4. targeted mutation in Tudor domain containing 1/mouse tudor repeat 1 (Tdrd1/Mtr-1), a tudor-related gene in mice, leads to male sterility because of postnatal spermatogenic defects

  5. Results suggest that Mili interacts with Tdrd1 in the nuage and chromatoid body, and that this interaction does not contribute to piRNA biogenesis but represents a regulatory mechanism that is critical for spermatogenesis.

  6. Tdrd1 ensures the entry of correct transcripts into the normal piRNA pool.

Zebrafish Tudor Domain Containing 1 (TDRD1) Interaktionspartner

  1. Tdrd1 is required for efficient Piwi-pathway activity and proper nuage formation. It binds Ziwi & Zili, with sequence specificity in the interaction between Tdrd1 tudor domains & symmetrically dimethylated arginines in Zili.

TDRD1 Protein Überblick

Protein Überblick

This gene is similar to a mouse gene that encodes a tudor domain protein. Alternatively spliced transcript variants have been described but their full length sequences have not been determined.

Alternative names and synonyms associated with TDRD1

  • tudor domain containing 1 (TDRD1)
  • tudor domain containing 1 (Tdrd1)
  • tudor domain containing 1 (tdrd1)
  • tudor domain-containing protein 1-like (LOC536516)
  • CT41.1 Protein
  • im:7155161 Protein
  • MTR-1 Protein

Bezeichner auf Proteinebene für TDRD1

tudor domain containing 1 , tudor domain containing protein 1 , cancer/testis antigen 41.1 , tudor domain-containing protein 1

GENE ID SPEZIES
423906 Gallus gallus
698388 Macaca mulatta
100027328 Monodelphis domestica
100068184 Equus caballus
56165 Homo sapiens
477826 Canis lupus familiaris
83561 Mus musculus
292129 Rattus norvegicus
553522 Danio rerio
536516 Bos taurus
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