anti-LIMD1 (LIMD1) Antikörper

Bezeichnung:
anti-LIM Domains Containing 1 Antikörper (LIMD1)
Auf www.antikoerper-online.de finden Sie aktuell 79 LIM Domains Containing 1 (LIMD1) Antikörper von 14 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen LIMD1 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 87 LIMD1 Produkte verfügbar.
Synonyme:
AW822033, D9Ertd192e, LIMD1, xlimd1
Alle Antikörper anzeigen Gen GeneID UniProt
LIMD1 494021  
LIMD1 8994 Q9UGP4
LIMD1 29806 Q9QXD8

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Weitere Synonyme anzeigen

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anti-Rat (Rattus) LIMD1 Antikörper:

anti-Human LIMD1 Antikörper:

anti-Mouse (Murine) LIMD1 Antikörper:

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Am meisten referenzierte anti-LIMD1 Antikörper

  1. Mouse (Murine) Polyclonal LIMD1 Primary Antibody für IHC (p), WB - ABIN657056 : Ghosh, Ghosh, Maiti, Mukherjee, Dutta, Roy, Roychoudhury, Panda: LIMD1 is more frequently altered than RB1 in head and neck squamous cell carcinoma: clinical and prognostic implications. in Molecular cancer 2010 (PubMed)
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Weitere Antikörper gegen LIMD1 Interaktionspartner

Human LIM Domains Containing 1 (LIMD1) Interaktionspartner

  1. These results suggested that LIMD1 is a novel BRCA2-interacting protein and is involved in the centrosome localization of BRCA2 (zeige BRCA2 Antikörper) and suppression of LIMD1, causing abnormal cell division in EC cells.

  2. Thus, the LIMD1-MYBL1 (zeige MYBL1 Antikörper) Index had considerable clinical value for DLBCL subtype classification and prognosis.

  3. Cyclic stretch is associated with a JNK (zeige MAPK8 Antikörper)-dependent increase in binding of a LATS (zeige LATS1 Antikörper) inhibitor, LIMD1, to the LATS1 (zeige LATS1 Antikörper) kinase and that reduction of LIMD1 expression suppresses the activation of YAP (zeige YAP1 Antikörper) by cyclic stretch.

  4. LIMD1 prevents retinoblastoma phosphorylation and downregulates of E2F1 (zeige E2F1 Antikörper) protein and blocks entry of cells into S-phase.

  5. Data show that the tumour suppressor protein LIMD1 acts as a molecular scaffold, simultaneously binding the PHDs and VHL (zeige VHL Antikörper), thereby assembling a PHD (zeige PDC Antikörper)-LIMD1-VHL (zeige VHL Antikörper) protein complex and creating an enzymatic niche that enables efficient degradation of HIF-1alpha (zeige HIF1A Antikörper).

  6. PU.1 is a major transcriptional activator of LIMD1

  7. LIMD1 inactivation as primary event than inactivation of RB1 (zeige RB1 Antikörper) in head and neck squamous cell carcinoma development.

  8. LIMD1 is a tumor-suppressor gene, the protein product of which functionally interacts with pRB (zeige RB1 Antikörper) and the loss of which promotes lung carcinogenesis

  9. These results suggest that some breast tumors have altered expression of LIMD1 RNA and that LIMD1 may be involved in cell anchoring via focal adhesions and in the cell cycle, particularly during mitosis.

  10. study demonstrates that LIMD1 represents a novel prognostic marker for breast cancer. Combined with the fact that LIMD1 expression is downregulated in lung cancers this clearly indicates that LIMD1 may represent a critical tumor suppressor gene

Mouse (Murine) LIM Domains Containing 1 (LIMD1) Interaktionspartner

  1. Limd1 regulates AP-1 (zeige JUN Antikörper) activation through an interaction with Traf6 (zeige TRAF6 Antikörper) to influence osteoclast development

  2. Limd1 influences not only stress osteoclastogenesis but also osteoblast function and osteoblast progenitor commitment. Together, these data identify Limd1 as a novel regulator of both bone osetoclast and bone osteoblast development and function.

LIMD1 Antigen-Profil

Beschreibung des Gens

Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, cell-cell adhesion, cell differentiation, proliferation and migration. Positively regulates microRNA (miRNA)-mediated gene silencing and is essential for P-body formation and integrity. Acts as a hypoxic regulator by bridging an association between the prolyl hydroxylases and VHL enabling efficient degradation of HIF1A. Acts as a transcriptional corepressor for SNAI1- and SNAI2/SLUG- dependent repression of E-cadherin transcription. Negatively regulates the Hippo signaling pathway and antagonizes phosphorylation of YAP1. Inhibits E2F-mediated transcription, and suppresses the expression of the majority of genes with E2F1- responsive elements. Regulates osteoblast development, function, differentiation and stress osteoclastogenesis. Enhances the ability of TRAF6 to activate adapter protein complex 1 (AP-1) and negatively regulates the canonical Wnt receptor signaling pathway in osteoblasts. May act as a tumor suppressor by inhibiting cell proliferation (By similarity).

Alternative names and synonyms associated with LIMD1

  • LIM domains containing 1 (limd1) Antikörper
  • LIM and cysteine-rich domains 1 (Lmcd1) Antikörper
  • LIM domains containing 1 (LIMD1) Antikörper
  • LIM domains containing 1 (Limd1) Antikörper
  • AW822033 Antikörper
  • D9Ertd192e Antikörper
  • LIMD1 Antikörper
  • xlimd1 Antikörper

Bezeichner auf Proteinebene für LIMD1

LIM domain-containing protein 1 , LIM and cysteine-rich domains protein 1 , dyxin , LIM domains-containing protein 1

GENE ID SPEZIES
549360 Xenopus (Silurana) tropicalis
494021 Rattus norvegicus
779085 Xenopus laevis
8994 Homo sapiens
484796 Canis lupus familiaris
29806 Mus musculus
617525 Bos taurus
316101 Rattus norvegicus
420701 Gallus gallus
100738579 Sus scrofa
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