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In zebrafish hair cells exogenous Ribeye (zeige CTBP2 ELISA Kits) B-domain and CtBP1 localize to the basal ends of synaptic ribbons.
Tel (zeige ETV6 ELISA Kits) orchestrates endothelial sprouting by binding to the generic co-repressor, CtBP (zeige CTBP2 ELISA Kits)
the importance of the oligomeric state of CtBP for coactivation of NeuroD1-dependent transcription, was investigated.
C-terminal binding protein 1 is a critical factor linking changes in cell metabolism to cell phenotype in hypoxic and other forms of pulmonary hypertension
CtBP1 increased breast tumor growth in MeS (zeige ME1 ELISA Kits) mice modulating multiple genes and miRNA expression implicated in cell proliferation, progenitor cells phenotype, epithelial to mesenchymal transition, mammary development and cell communication in the xenografts.
These data uncovered that CtBP1 protein is a valuable marker of glioma pathogenic process and that CtBP1 can serve as a novel prognostic marker for glioma therapy.
human chorionic gonadotropin stimulated miR (zeige MLXIP ELISA Kits)-212, which down-regulated OLFM1 (zeige OLFM1 ELISA Kits) and CTBP1 expression in fallopian and endometrial epithelial cells to favor spheroid attachment
It is a putative target gene of miR (zeige MLXIP ELISA Kits)-137 in breast neoplasms.
CtBP physically interacted with TCF-4, and this interaction was significantly inhibited in the presence of MTOB. The above findings point to a novel role of CtBPs in the promotion of CSC growth and self-renewal
High CtBP1 expression is associated with Prostate tumor.
C-terminal-binding protein (CtBP (zeige CTBP2 ELISA Kits)) was found to have an essential role in promoting glutaminolysis by directly repressing the expression of SIRT4 (zeige SIRT4 ELISA Kits).
MCRIP1, an ERK (zeige EPHB2 ELISA Kits) substrate, mediates ERK (zeige EPHB2 ELISA Kits)-induced gene silencing during epithelial-mesenchymal transition by regulating the co-repressor CtBP (zeige CTBP2 ELISA Kits).
Study determined that PCBP2 (zeige PCBP2 ELISA Kits) specifically associates with components of this kinase cascade and regulates the activities of its downstream transcriptional coactivators.
data suggest that PCBP2 (zeige PCBP2 ELISA Kits) regulates p73 (zeige ARHGAP24 ELISA Kits) expression via mRNA stability and p73 (zeige ARHGAP24 ELISA Kits)-dependent biological function in ROS (zeige ROS1 ELISA Kits) production and cellular senescence.
PCBP2 (zeige PCBP2 ELISA Kits) overexpression rescues the Meis1 (zeige MEIS1 ELISA Kits) effects of Akt (zeige AKT1 ELISA Kits)-mTOR (zeige FRAP1 ELISA Kits) pathway and hypertrophy of cardiomyocytes.
These data reveal that Pcbp1 (zeige PCBP1 ELISA Kits) and Pcbp2 (zeige PCBP2 ELISA Kits) are individually essential for mouse embryonic development and have distinct impacts on embryonic viability and that Pcpb2 has a nonredundant in vivo role in hematopoiesis.
PCBP2 (zeige PCBP2 ELISA Kits) knockdown promoted angiotensin II-induced hypertrophy (increase in cell size, protein synthesis and activation of fetal genes) of cardiomyocytes, while PCBP2 (zeige PCBP2 ELISA Kits) overexpression obtained oppose effects.
Our analysis of PCBP1 (zeige PCBP1 ELISA Kits) and PCBP2 (zeige PCBP2 ELISA Kits) expression demonstrates robust expression of these two proteins within the gastric epithelium with high concordance for both proteins in their cell-type specificities and intracellular distributions.
This study demonstrates for the first time that alpha-CP2 (zeige PCBP2 ELISA Kits) functions as a transcriptional activator by binding to a single-stranded poly(C) sequence.
This study provides evidence that PCBP2 (zeige PCBP2 ELISA Kits) and hnRNP A1 (zeige HNRNPA1 ELISA Kits) bind to the 5' and 3' ends of the murine norovirus 1 viral RNA and contribute to RNA circularization, playing a role in the virus life cycle.
CtBP1 protein is not essential for the formation of functional ribbon synapses in the retina.
This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.
C-terminal binding protein 1
, C-terminal-binding protein 1
, C-terminal-binding protein 1-like
, c-terminal-binding protein 1-like
, brefeldin A-ribosylated substrate
, C-terminal-binding protein A
, 50 kDa BFA-dependent ADP-ribosylation substrate
, 50-kDa BFA-induced ADP-ribosylated substrate
, C-terminal-binding protein 3
, C-terminus binding protein 3/brefeldin A (BFA) adenosine diphosphate-ribosylated substrate
, brefeldin A-ADP-riboslyated substrate
, heterogeneous nuclear ribonucleoprotein X
, hnRNP X
, poly(rC)-binding protein 2
, putative heterogeneous nuclear ribonucleoprotein X