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anti-Human SPAG9 Antikörper:
anti-Mouse (Murine) SPAG9 Antikörper:
anti-Rat (Rattus) SPAG9 Antikörper:
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SPAG9 mRNA and protein overexpression in lung cancer tissue, and the presence of SPAG9 IgG antibody in peripheral blood of lung cancer patients indicates that it has potential as a biomarker for lung cancer diagnosis.
SPAG9-elevated expression contributes to malignant behavior and poor prognosis of breast cancer and may support a potential indicator in treatment selection.
Study suggest that suppression of miR (zeige MLXIP Antikörper)-141 may cause an aberrant overexpression of SPAG9 promoting growth and metastasis of hepatocellular carcinoma cells.
expression of SPAG9 in ECC cells with TGF-beta1 (zeige TGFB1 Antikörper) treatment and spheroids formation was increased
PLK1 (zeige PLK1 Antikörper) binding to JIP4 was found in G2 phase and mitosis, and PLK1 (zeige PLK1 Antikörper) binding was self-primed by PLK1 (zeige PLK1 Antikörper) phosphorylation of JIP4.
Based on in vitro assays, we found miR (zeige MLXIP Antikörper)-200a-3p significantly inhibit cancer cell proliferation by inducing apoptosis.
FOXK1 (zeige FOXK2 Antikörper) protein levels and activity are regulated by associating with JLP and PLK1 (zeige PLK1 Antikörper)
SPAG9 overexpression in gastric cancer correlates with poor prognosis and contributes to gastric cancer cell proliferation
SPAG9 was upregulated in nonmelanoma skin cancer when compared with normal skin.
SPAG9 expression is significantly increased in prostate cancer and it may be involved in the process of prostate cancer cell motility, migration and angiogenesis.
JLP-deficiency impaired T-cell proliferation.
data establish JSAP1 (zeige MAPK8IP3 Antikörper) and JLP as positive regulators of kinesin-1-dependent axonal transport, which prevents neuronal degeneration.
JSAP1 (zeige MAPK8IP3 Antikörper) and JLP play critical roles in kinesin-1-dependent axonal transport
JSAP1 (zeige MAPK8IP3 Antikörper) and JLP, which might be paralogous to each other, are critical and functionally redundant in cytokinesis and control ARF6 (zeige ARF6 Antikörper) localization to the midbody by forming a tripartite complex of JSAP1 (zeige MAPK8IP3 Antikörper)/JLP, active ARF6 (zeige ARF6 Antikörper), and kinesin-1.
JLP in skin basal keratinocytes plays an important role in UVB-induced apoptosis by modulating p38 MAPK (zeige MAPK14 Antikörper) signaling pathways.
Data indicate a role of a scaffolding protein JLP in the regulation of surface CD40 (zeige CD40 Antikörper) expression and fine-tuning of dendritic cell (DC) function.
A functional role for JLP in the gep (zeige GRN Antikörper) oncogene (zeige RAB1A Antikörper)-regulated neoplastic signaling pathway.
describe a protein, JLP, which acts as a scaffolding protein to bring mitogen-activated protein kinases and their target transcription factors together for the execution of specific signaling pathways
The JIP4 scaffold protein (zeige HOMER1 Antikörper) therefore appears to be a new component of the p38 MAP kinase (zeige MAPK14 Antikörper) signaling pathway
analysis of a novel protein-protein interaction between KLC1 and JLP that involves leucine zipper-like domains
This gene encodes a member of the cancer testis antigen gene family. The encoded protein functions as a scaffold protein that structurally organizes mitogen-activated protein kinases and mediates c-Jun-terminal kinase signaling. This protein also binds to kinesin-1 and may be involved in microtubule-based membrane transport. This protein may play a role in tumor growth and development. Alternate splicing results in multiple transcript variants.
JNK-associated leucine-zipper protein
, sperm associated antigen 9
, C-Jun-amino-terminal kinase-interacting protein 4
, C-Jun-amino-terminal kinase-interacting protein 4-like
, c-Jun-amino-terminal kinase-interacting protein 4-like
, JNK interacting protein
, JNK/SAPK-associated protein
, Max-binding protein
, c-Jun NH2-terminal kinase-associated leucine zipper protein
, cancer/testis antigen 89
, human lung cancer oncogene 6 protein
, lung cancer oncogene 4
, mitogen-activated protein kinase 8-interacting protein 4
, proliferation-inducing gene 6
, protein highly expressed in testis
, sperm surface protein
, sunday driver 1
, JNK-interacting leucine zipper
, JNK-interacting protein 4
, JNK/SAPK-associated protein 2
, sperm-associated antigen 9