anti-MEGF10 (MEGF10) Antikörper

Bezeichnung:
anti-Multiple EGF-Like-Domains 10 Antikörper (MEGF10)
Auf www.antikoerper-online.de finden Sie aktuell 16 Multiple EGF-Like-Domains 10 (MEGF10) Antikörper von 2 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen MEGF10 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 23 MEGF10 Produkte verfügbar.
Synonyme:
3000002B06Rik, EMARDD, Gm331
Alle Antikörper anzeigen Gen GeneID UniProt
MEGF10 291445  
MEGF10 84466 Q96KG7
MEGF10 70417 Q6DIB5

Alle Spezies anzeigen

Weitere Synonyme anzeigen

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anti-Rat (Rattus) MEGF10 Antikörper:

anti-Human MEGF10 Antikörper:

anti-Mouse (Murine) MEGF10 Antikörper:

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Weitere Antikörper gegen MEGF10 Interaktionspartner

Human Multiple EGF-Like-Domains 10 (MEGF10) Interaktionspartner

  1. Concentrating on hypermethylated genes to identify candidate tumor suppressor loci, the study found the cell engulfment and adhesion factor gene MEGF10 to be epigenetically repressed by DNA hypermethylation or by H3K27/K9 methylation in neuroblastoma (zeige ARHGEF16 Antikörper) cell lines.

  2. MEGF10 mutations can cause myopathy with adult-onset respiratory insufficiency

  3. results indicate that myogenin (zeige MYOG Antikörper) is a positive regulator in transcriptional regulation of MEGF10 in skeletal muscle

  4. Mutations in MEGF10 cause a recessive congenital myopathy with minicores and suggest satellite cell dysfunction as the pathogenic mechanism

  5. Mutations in MEGF10, a regulator of satellite cell myogenesis, cause early onset myopathy, areflexia, respiratory distress and dysphagia (EMARDD)

  6. The results of this study suggested that no association between schizophrenia and rs27388 of the MEGF10 gene in Chinese case-control sample.

  7. MEGF10 is involved in the uptake of amyloid-beta peptide (Abeta42) in the brain.

  8. in a system of forced expression by transfection, MEGF10 function can be modulated by the ATP binding cassette transporter ABCA1, ortholog to CED-7

  9. Human MEGF10 is an ortholog of Ced1 (zeige IFT122 Antikörper).

  10. An interaction between MEGF10 and clathrin assembly protein complex 2 medium chain (AP50 (zeige AP2M1 Antikörper)), a component of clathrin-coated pits was identified.

Mouse (Murine) Multiple EGF-Like-Domains 10 (MEGF10) Interaktionspartner

  1. Megf10 binds with high affinity to C1q, an eat-me signal for apoptotic cells. Cells expressing Megf10 with EMARDD mutations have impaired apoptotic cell clearance and impaired binding to C1q.

  2. studies reveal a novel role for astrocytes in mediating synapse elimination in the developing and adult brain, identify MEGF10 and MERTK (zeige MERTK Antikörper) as critical proteins in the synapse remodelling underlying neural circuit refinement

  3. Cysteine mutations cause defective tyrosine phosphorylation in MEGF10 myopathy.

  4. These results indicated that both Jedi-1 (zeige PEAR1 Antikörper) and MEGF10 can mediate phagocytosis independently through the recruitment of Syk (zeige SYK Antikörper).

  5. in mouse, two related transmembrane proteins, MEGF10 and MEGF11 (zeige MEGF11 Antikörper), have critical roles in the formation of mosaics by two retinal interneuron subtypes, starburst amacrine cells and horizontal cells

  6. Megf10 represents a novel transmembrane protein that impinges on Notch (zeige NOTCH1 Antikörper) signaling to regulate the satellite cell population balance between proliferation and differentiation.

MEGF10 Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the multiple epidermal growth factor-like domains protein family. The encoded protein plays a role in cell adhesion, motility and proliferation, and is a critical mediator of apoptotic cell phagocytosis as well as amyloid-beta peptide uptake in the brain. Expression of this gene may be associated with schizophrenia, and mutations in this gene are a cause of early-onset myopathy, areflexia, respiratory distress, and dysphagia (EMARDD) as well as congenital myopathy with minicores. Alternatively spliced transcript variants have been observed for this gene.

Alternative names and synonyms associated with MEGF10

  • multiple EGF-like domains 10 (Megf10) Antikörper
  • multiple EGF-like-domains 10 (MEGF10) Antikörper
  • multiple EGF-like-domains 10 (Megf10) Antikörper
  • 3000002B06Rik Antikörper
  • EMARDD Antikörper
  • Gm331 Antikörper

Bezeichner auf Proteinebene für MEGF10

multiple epidermal growth factor-like domains protein 10 , multiple EGF-like domains protein 10

GENE ID SPEZIES
291445 Rattus norvegicus
84466 Homo sapiens
70417 Mus musculus
427126 Gallus gallus
474665 Canis lupus familiaris
100515713 Sus scrofa
539136 Bos taurus
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