SP1 Proteine (SP1)

Bezeichnung:
Sp1 Transcription Factor Proteine (SP1)
Auf www.antikoerper-online.de finden Sie aktuell 9 Sp1 Transcription Factor (SP1) Proteine von 6 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen SP1 Antikörper (286) und SP1 Kits (25) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 334 SP1 Produkte verfügbar.
Synonyme:
1110003E12Rik, AA450830, AI845540, fc18h09, SP1, Sp1-1, wu:fc18h09, zgc:85950
alle Proteine anzeigen Gen GeneID UniProt
SP1 6667 P08047
Ratte SP1 SP1 24790 Q01714
SP1 20683 O89090

Weitere Synonyme anzeigen

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Weitere Proteine zu SP1 Interaktionspartnern

Zebrafish Sp1 Transcription Factor (SP1) Interaktionspartner

  1. A hierarchic gene expression of copper homeostatic genes was demonstrated between atp7a (zeige ATP7A Proteine), sp1 and sod1 (zeige SOD1 Proteine) in zebrafish.

  2. zebrafish Sp1-like protein is structurally and functionally comparable to human Sp1

Human Sp1 Transcription Factor (SP1) Interaktionspartner

  1. Data indicate that DNMT3A (zeige DNMT3A Proteine) allele G of rs1550117 was associated with an increased risk of non-small cell lung cancer (NSCLC) susceptibility and binding affinity of transcription repressor SP1 (zeige PSG1 Proteine).

  2. Sp1 (zeige PSG1 Proteine)-DNA binding affinity is reduced under Cu replete conditions but increased under reduced Cu conditions.

  3. Triptolide downregulates Sp1 (zeige PSG1 Proteine) and HSP70 (zeige HSP70 Proteine) mRNA in gastric cancer cell lines.

  4. Data indicate that interleukin 1alpha (IL-1alpha) propiece can activate NF-kappa B (NFkappaB (zeige NFKB1 Proteine)) and Sp1 transcription factor (SP1).

  5. miR (zeige MLXIP Proteine)-31-5p acted as a tumor suppressor to regulate SP1 (zeige PSG1 Proteine), miR (zeige MLXIP Proteine)-31-5p could be used as a therapeutic target for the treatment ofhepatocellular carcinoma.

  6. the overexpression of miR (zeige MLXIP Proteine)-141 augments anoikis resistance in ovarian cancer cells by targeting and repressing the expression of KLF12 (zeige KLF12 Proteine), which, in turn, competes for binding sites in the survivin (zeige BIRC5 Proteine) promoter with Sp1 (zeige PSG1 Proteine). The subsequent increase in survivin (zeige BIRC5 Proteine) then protects ovarian cancer cells against anoikis by blocking the intrinsic apoptotic activity.

  7. this study uncovered the mechanism through which mithramycin inhibits epithelial-to-mesenchymal transition and invasion in salivary adenoid cystic carcinoma cell lines, namely, via downregulating specificity protein 1 and SNAI1 (zeige SNAI1 Proteine) expression, which suggests mithramycin may be a promising therapeutic option for salivary adenoid cystic carcinoma.

  8. the two Q-domains of Sp1 (zeige PSG1 Proteine) and four Q-domains of TAF4 (zeige TAF4 Proteine) were disordered under physiological conditions.

  9. Taken together, these findings collectively demonstrate that microRNA-337 exerts its tumor-suppressing roles in cervical cancer by directly targeting specificity protein 1, thereby indicating a potential novel potential therapeutic target for patients with cervical cancer.

  10. findings support the idea that RYBP (zeige RYBP Proteine) may represent a target for cancer therapy and suggest that it may be useful as a prognostic biomarker for HCC (zeige FAM126A Proteine), either alone or in combination with KLF4 (zeige KLF4 Proteine) and Sp1 (zeige PSG1 Proteine)

Cow (Bovine) Sp1 Transcription Factor (SP1) Interaktionspartner

  1. study demonstrates the co-expression of DLX3 (zeige DLX3 Proteine), PPARG (zeige PPARG Proteine) and SP1 in trophoblast binucleated cell (BNC)nuclei; this suggests a possible role of these transcription factors through BNC specific genes at the time of pre-placental differentiation

  2. likely involvement of the Sp family in regulating PTH (zeige PTH Proteine) gene expression through interactions with an Sp1 DNA element in the hormone's promoter.

  3. These results demonstrate that the single nucleotide polymorphism alters the bovine FASN promoter activity in vitro and the Sp1/Sp3 binding ability of the sequence.

  4. The coordinate regulation of the bovine PRNP (zeige PRNP Proteine) promoter suggests the two Sp1 binding site polymorphisms control Sp1 binding to the PRNP (zeige PRNP Proteine) promoter and its activity.

Mouse (Murine) Sp1 Transcription Factor (SP1) Interaktionspartner

  1. Results suggest that 25-hydroxycholesterol (25-HC) induced the interaction between NFATc1 (zeige NFATC1 Proteine) and Sp1, reducing the level of free Sp1 to inhibit microRNA miR (zeige MLXIP Proteine)-139-5p expression and promote osteoclastogenesis.

  2. data indicated that (-)-Epicatechin inhibited AngII-induced cardiac hypertrophy by activating the SP1/SIRT1 (zeige SIRT1 Proteine) signaling pathway.

  3. This resulted in Sp1 displacement from the promoter and binding of Sp3 to it, leading to p300 recruitment and histone acetylation, activating transcription. This is the first study addressing the mechanisms of physiological TLR5 expression in the intestine. Additionally, a novel insight is gained into Sp1/Sp3-mediated gene regulation that may apply to other genes

  4. adrenergic stimulation induced complex formation between Ifrd1 (zeige IFRD1 Proteine), Sp1 and mSIN3B, which is a component of the SIN (zeige POLR3E Proteine) complex containing histone deacetylase (zeige HDAC1 Proteine), in brown adipocytes. These findings, therefore, suggest that Ifrd1 (zeige IFRD1 Proteine) could be a pivotal negative regulator of sympathetic regulation of thermogenic and mitochondrial gene expression in brown adipocytes by interacting with Sp1 and the mSIN3 complex.

  5. Dp71 (zeige DMD Proteine) expression in hepatic cells is carried out, in part, by YY1 (zeige YY1 Proteine)-, Sp1- and Sp3-mediated transcription from the Dp71 (zeige DMD Proteine) promoter.

  6. SP1 expression was up-regulated in the tubular epithelial cells after acute kidney injury induced by ischemia-reperfusion.MiR-204 regulates epithelial-mesenchymal transition by targeting SP1 in the tubular epithelial cells.

  7. miR (zeige MLXIP Proteine)-124, -128, and -137 act synergistically to regulate Sp1 expression.

  8. YY1 (zeige YY1 Proteine) and SP1 independently and cooperatively govern the Mesp1 (zeige MESP1 Proteine) expression during embryogenesis.

  9. Taken together, these results indicate that the transcription factor Sp1 upregulates the proximal promoter activity of the mouse Col11a1 gene in chondrocytes.

  10. In the initial stage of myocyte differentiation, transcription of the YB-1 (zeige YBX1 Proteine) gene was regulated by E2F1 (zeige E2F1 Proteine) and Sp1, and was then gradually replaced under the control of both MyoD (zeige MYOD1 Proteine) and myogenin (zeige MYOG Proteine).

SP1 Protein Überblick

Protein Überblick

The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with SP1

  • sp1 transcription factor (sp1)
  • Sp1 transcription factor (sp1)
  • Sp1 transcription factor (SP1)
  • Sp1 transcription factor (LOC100351317)
  • Sp1 transcription factor (Sp1)
  • trans-acting transcription factor 1 (Sp1)
  • 1110003E12Rik Protein
  • AA450830 Protein
  • AI845540 Protein
  • fc18h09 Protein
  • SP1 Protein
  • Sp1-1 Protein
  • wu:fc18h09 Protein
  • zgc:85950 Protein

Bezeichner auf Proteinebene für Sp1 Transcription Factor Proteine (SP1)

Sp1-like protein , transcription factor Sp1 , transcription factor , Sp1 transcription factor , transcription factor Sp1-like , specificity protein 1 , specific protein-1 , trans-acting transcription factor 1

GENE ID SPEZIES
324109 Danio rerio
394744 Xenopus (Silurana) tropicalis
451939 Pan troglodytes
702710 Macaca mulatta
100351317 Oryctolagus cuniculus
100407824 Callithrix jacchus
100440745 Pongo abelii
100474983 Ailuropoda melanoleuca
100553756 Anolis carolinensis
100585963 Nomascus leucogenys
6667 Homo sapiens
540741 Bos taurus
24790 Rattus norvegicus
397314 Sus scrofa
431939 Xenopus laevis
395303 Gallus gallus
486507 Canis lupus familiaris
100303456 Ovis aries
20683 Mus musculus
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